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周剑
2023-05-10 19:33
  • 周剑
  • 周剑 - 教授 博导-华东师范大学-化学与分子工程学院-个人资料

近期热点

资料介绍

个人简历


2008.11 - 至今:华东师范大学化学系‚教授、博导\r
2005.10 - 2008.9:德国马普煤炭研究所Benjamin List教授小组进行博士后研究\r
2004. 9 - 2005. 8:日本东京大学药学院Shu Kobayashi教授小组进行博士后研究\r
1999. 9-2004. 7:上海有机化学研究所‚在唐勇研究员指导下进行硕博连读‚研究生会主席\r
1997. 7 - 1999. 8:四川教育学院组织人事处‚助教;\r
1993. 9 - 1997. 7:四川师范大学化学系‚校学生会主席

研究领域


"""""具有四取代碳手性中心的不对称催化构建\r
四取代碳手性中心广泛存在于天然产物和药物分子中

近期论文


B.-S. Mu, X.-Y. Cui, X.-P. Zeng, J.-S. Yu and J. Zhou. Modular synthesis of chiral 1,2-dihydropyridines via Mannich/Wittig/cycloisomerization sequence that internally reuses waste. Nature Communications, 2021, In press.\r
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K. Liao, Y. Gong, R.-Y. Zhu, C. Wang, F. Zhou* and J. Zhou*. Highly Enantioselective CuAAC of Functional Tertiary Alcohols Featuring an Ethynyl Group and Their Kinetic Resolution. Angew. Chem. Int. Ed. 2021, doi.org/10.1002/anie.202016286\r
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X.-S. Hu, J.-X. He, S.-Z. Dong, Q.-H. Zhao, J.-S. Yu and J. Zhou*. Regioselective Markovnikov hydrodifluoroalkylation of alkenes using difluoroenoxysilanes. Nature Communications, 2020, doi.org/10.1038/s41467-020-19387-4.\r
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P.-G. Ding, X.-S. Hu, J.-S. Yu* and J. Zhou*. Diastereodivergent Synthesis of α-Chiral Tertiary Azides through Catalytic Asymmetric Michael Addition. Org. Lett. 2020, doi/10.1021/acs.orglett.0c03178.\r
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Y. Shi, B.‐W. Pan, J.‐S. Yu. Y. Zhou, J. Zhou*. Recent Advances in Applying Carbonyl‐stabilized Phosphorus Ylides for Catalysis. ChemCatChem, 2020, 12, doi.org/10.1002/cctc.202001371.\r
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F. Zhou*, L. Zhu, B.-W. Pan, Y. Shi, Y.-L. Liu, J. Zhou*. Catalytic enantioselective construction of vicinal quaternary carbon stereocenters. Chem. Sci. 2020, 11, 9341–9365.\r
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W.-B. Wu, J.-S. Yu, J. Zhou*. Catalytic Enantioselective Cyanation: Recent Advances and Perspectives. ACS Catal. 2020, 10, 7668−7690.\r
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Q. Xiao, J.-S. Yu, Y.-F. Wang, D.-J. Ma, J. Zhou*, and X. Lou*. 3-Difluoroalkyl Quaternary Oxindoles Inhibit Macrophage Pyroptosis by Blocking Inflammasome Recruitment of Caspase-1. ACS Med. Chem. Lett. 2020, 11, 1392−1401.\r
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C. Wang, F. Zhou, J. Zhou* .Recent Advances in the Enantioselective Copper(I)-Catalyzed Azide-Alkyne Cycloaddition Reaction. Chin. J. Org. Chem. 2020, 40, DOI: 10.6023/cjoc202005020.\r
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F. Zhou*, J. Zhou*.Ni-Catalyzed Desymmetrization of Malononitriles to Cycloenones with a Nitrile-Containing All-Carbon Quaternary Center. Chin. J. Org. Chem. 2020, 40, 2180-2181.\r
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P.-G. Ding, F. Zhou, X. Wang, Q.-H. Zhao, J.-S. Yu and J. Zhou*. H-Bond donor-directed switch of diastereoselectivity in the Michael addition of α-azido ketones to nitroolefins. Chem. Sci. 2020, DOI: 10.1039/D0SC00475H.\r
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C. Chen, W.-B. Wu, Y.-H. Li, Q.-H. Zhao, J.-S. Yu, J. Zhou*. Activation of Chiral (Salen)TiCl2 Complex by Phosphorane for the Highly Enantioselective Cyanation of Nitroolefins. Org. Lett. 2020, 22, 2099−2104.\r
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W.-B. Wu, X.-P. Zeng, J. Zhou* Carbonyl-Stabilized Phosphorus Ylide as an Organocatalyst for Cyanosilylation Reactions Using TMSCN. J. Org. Chem. 2020, DOI: 10.1021/acs.joc.9b03347\r
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C. Wang, R.-Y. Zhu, K. Liao, F. Zhou, J. Zhou* . Enantioselective Cu(I)-Catalyzed Cycloaddition of Prochiral Diazides with Terminal or 1-Iodoalkynes. Org. Lett. 2020‚ 22, 1270-1274.\r
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Y.-H. Wang, Z.-Y. Cao, Q.-H. Li, G.-Q. Lin, J. Zhou*, and P. Tian*. Activating Pronucleophiles with High pKa Values: Chiral Organo-Superbases. Angew. Chem. Int. Ed. 2020, DOI:10.1002/anie.201913484\r
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Y.-H. Wang, J.-S. Tian, P.-W. Tan, Q. Cao, X.-X. Zhang, Z.-Y. Cao, F. Zhou, X. Wang, and J. Zhou*. Regiodivergent Intramolecular Nucleophilic Addition of Ketimines for the Diverse Synthesis of Azacycles. Angew. Chem. Int. Ed. 2020, 59, 1634 –1643.\r
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R.-Y. Zhu, L. Chen, X.-S. Hu, F. Zhou and J. Zhou*. Enantioselective synthesis of P-chiral tertiaryphosphine oxides with an ethynyl group via Cu(I)-catalyzed azide–alkyne cycloaddition. Chem. Sci. 2020, 11, 97–106.\r
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S.-L. Xie, X.-T Gao, F. Zhou, H.-H. Wu, J. Zhou*. Enantioselective carboxylative cyclization of propargylic alcohol with carbondioxide under mild conditions. Chin. Chem. Lett. 2020, 31, 324–328.\r
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Y. Gong, Z.-Y. Cao, Y.-B. Shi, F. Zhou, Y. Zhou and J. Zhou*. A highly efficient Hg(OTf)2-mediated Sakurai–Hosomiallylation of N-tert butyloxycarbonylamino sulfones, aldehydes, fluoroalkylketones and α,β-unsaturated enones usingallyltrimethylsilane. Org. Chem. Front. 2019, 6, 3989–3995.\r
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Y.-P. Tian, Y. Gong, X.-S. Hu, J.-S. Yu, Y. Zhou and J. Zhou*. HClO4 catalysedaldol-type reaction of fluorinated silyl enol ethers with acetals or ketalstoward fluoroalkyl ethers. Org. Biomol. Chem. 2019, 17, 9430–9434.

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