个人简历

教育经历\r
2011.09 - 2016.06 华东师范大学 化学与分子工程学院 博士 (导师：周剑教授)\r
2007.09 - 2011.07 江西师范大学 化学化工学院 学士 (导师：丁秋平教授)\r
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工作经历\r
2019.02 - 至今： 华东师范大学 化学与分子工程学院 青年研究员 （紫江青年学者）\r
2017.01 - 2019.01 日本微生物化学研究所 (JSPS博士后，导师：Masakatsu Shibasaki教授)\r
2016.07 - 2017.01 上海药明康德新药开发有限公司 (高级研究员)

研究领域

"""""含氟、含硅有机化合物的高效高选择性构建及其应用研究；绿色农药创制研究"

近期论文

W.-B. Wu, B.-S. Mu, J.-S. Yu*, J. Zhou, Me2(CH2=CH)SiCN: a bifunctional ethylene equivalent for Diels-Alder reaction based controllable tandem synthesis. Chem. Sci. 2022, 13, 3519-3525.\r
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X.-X. Zhang, Y. Zhang, L. Liao, Y. Gao, H. E. M. Su*, J.-S. Yu*, Catalytic Asymmetric Isomerization of (Homo)Allylic Alcohols: Recent Advances and Challenges. ChemCatChem 2022, 14, e202200126.\r
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B.-S. Mu, X.-Y. Cui, X.-P. Zeng, J.-S. Yu,* J. Zhou,* Modular synthesis of chiral 1,2-dihydropyridines via Mannich/Wittig/cycloisomerization sequence that internally reuses waste. Nat. Commun. 2021, 12, 2219.\r
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C.-W. Lei, B.-S. Mu, F. Zhou,* J.-S. Yu,* Y. Zhou,* J. Zhou, Organocatalytic enantioselective reactions involving prochiral carbocationic intermediates. Chem. Commun. 2021, 57, 9178-9191.\r
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J.-X. He, Y. Zhang, B.-S. Mu, X.-Y. Cui, J. Zhou, J.-S. Yu,* Catalyst-Free and Solvent-Controlled Divergent Synthesis of Difluoromethylene-Containing S-Heterocycles.J. Org. Chem. 2021, 86, 9206-9217.\r
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X.-S. Hu, J.-X. He, Y. Zhang, J. Zhou, J.-S. Yu,* Highly Stereoselective Positional Isomerization of Styrenes via Acid-Catalyzed Carbocation Mechanism. Chin. J. Chem. 2021, 39, 2227-2233.\r
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X.-X. Zhang, Y. Gao, X.-S. Hu, C.-B. Ji,* Y.-L. Liu, J.-S. Yu*, Recent Advances in Catalytic Enantioselective Synthesis of Fluorinated alpha- and beta-Amino Acids. Adv. Synth. Catal. 2020,362, 4763 (VIP, Cover picture).\r
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Q. Xiao, J.-S. Yu (co-first author), Y. Wang, D. Ma, J. Zhou*, and X. Lou*, 3-Difluoroalkyl Quaternary Oxindoles Inhibit Macrophage Pyroptosis by Blocking Inflammasome Recruitment of Caspase-1. ACS Med. Chem. Lett.2020, 11, 1392–1401.\r
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X.-S. Hu, J.-X. He, S.-Z. Dong, Q.-H. Zhao, J.-S. Yu*, J. Zhou*, Regioselective Markovnikov hydrodifluoroalkylation of mono-, di-, tri-, and tetrasubstituted alkenes using difluoroenoxysilanes. Nature Commun. 2020, 11, 5500.\r
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P.-G. Ding, X.-S. Hu, J.-S. Yu*, J. Zhou*, Diastereodivergent Synthesis of α-Chiral Tertiary Azides through Catalytic Asymmetric Michael Addition. Org. Lett. 2020, DOI: 10.1021/acs.orglett.0c03123.\r
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B.-W. Pan, Y. Shi, Y.-P. Tian, J.-S. Yu*, Y. Zhou*, J. Zhou*, Synthesis of Multifunctional α,α-Difluoroketones through Allylic Alkylation of Difluoroenoxysilanes with MBH Carbonates. Chem. Asian J. 2020, DOI: 10.1002/asia.202001145.\r
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Y. Shi, B.-W. Pan, J.-S. Yu*, Y. Zhou,* J. Zhou*, Recent Advances in Applying Carbonyl-stabilized Phosphorus Ylides for Catalysis. ChemCatChem 2020, DOI: 10.1002/cctc.202001371.\r
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Y.-J. Hao, Y. Gong, Y. Zhou,* J. Zhou, J.-S. Yu*, Construction of beta-Quaternary α,α-Difluoroketones via Catalytic Nucleophilic Substitution of Tertiary Alcohols with Difluoroenoxysilanes. Org. Lett. 2020, DOI: 10.1021/acs.orglett.0c03123.\r
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W.-B. Wu, J.-S. Yu*, J. Zhou* Catalytic Enantioselective Cyanation: Recent Advances and Perspectives. ACS Catal. 2020, 10, 7668.\r
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Y.-J. Hao, X.-S. Hu, Y. Zhou*, J. Zhou, J.-S. Yu*, Catalytic Enantioselective α-Arylation of Carbonyl Enolates and Related Compounds. ACS Catal. 2020, 10, 955-993.\r
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X.-S. Hu, J.-S. Yu*, J. Zhou*, Catalytic selective mono- and difluoroalkylation using fluorinated silyl enol ethers. Chem. Commun. 2019, 55, 13638-13648.\r
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X.-S. Hu, P.-G. Ding, J.-S. Yu*, J. Zhou*, A Sc(OTf)3 catalyzed Mukaiyama-Mannich reaction of difluoroenoxysilanes with unactivated ketimines. Org. Chem. Front. 2019, 6, 2500-2505.\r
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Y.-P. Tian, Y. Gong, Hu, X.-S. Hu, J.-S. Yu*, Y. Zhou*, J. Zhou*, HClO4 catalysed aldol-type reaction of fluorinated silyl enol ethers with acetals or ketals toward fluoroalkyl ethers. Org. Biomol. Chem. 2019, 17, 9430-9434.\r
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K. Liao, X.-S. Hu, R.-Y. Zhu, R.‐H. Rao, J.-S. Yu*, F. Zhou, J. Zhou*, Catalytic Enantioselective Protonation of Monofluorinated Silyl Enol Ethers towards Chiral α-Fluoroketones. Chin. J. Chem. 2019, 37, 799-806. (封面文章)\r
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P.-W. Xu, J.-S. Yu*, C. Chen, Z.-Y. Cao, F. Zhou, J. Zhou*, Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters. ACS Catal. 2019, 9, 1820-1882.