个人简历
学习、工作经历 2015.12-至今 华东师范大学生命医学研究所,研究员,博士生导师； 2010.1-2015.12 华东师范大学生命医学研究所，副教授（破格）； 2007.7-2009．12华东师范大学生命医学研究所，讲师； 2005.11-2007.6 博士学位，美国Texas A&M University与华东师范大学联合培养； 2004.6-2005.11 博士生，华东师范大学生命科学学院； 2001.9-2004.6 硕士学位，湖南师范大学生命科学学院； 2012.10 上海市委党校/组织部第27期留学回国人员研修班。
研究领域
1、抗肿瘤新药研发（前列腺癌、乳腺癌、结肠癌、胰腺癌、淋巴瘤、白血病等）；2、新型医用材料研发。
近期论文
2. A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer.通讯作者3. Yu QHan YWang XQin CZhai DChang JXiao YWu CACS Nano.通讯作者4. An aligned porous electrospun fibrous membrane with controlled drug delivery- an efficient strategy to accelerate diabetic wound healing with improved angiogenesis.通讯作者5. ,,,,,,,,,,,,,.Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer. EBioMedicine.2018May;31:276-286. doi: 10.1016/j.ebiom.2018.05.003 年6. Wang XLv FLi THan YACS Nano. 7. A conducive bioceramic/polymer composite biomaterial for diabetic wound healing.通讯作者8. The synthesis and antitumor activity of lithocholic acid and its derivatives.9. Novel hemostatic agents based on gelatin-microbial transglutaminase mix.通讯作者10. Ailanthone: a new potential drug for castration-resistant prostate cancer.通讯作者11. 通讯作者12. 通讯作者13. 通讯作者14. The synthesis and antistaphylococcal activity of 9, 13-disubstituted berberine derivatives.通讯作者年15. *, Yi Z*, Liu M*. Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer. Nature communications. 2016 Dec 13;7:13122. doi: 10.1038/ncomms13122. (SCI,IF =11.5,通讯作者16. Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways.通讯作者17. Novel 3,4-seco bile acid diamides as selective anticancer proliferation and migration agents.通讯作者18. Wang YY, He Y, Yang LF, Peng SH, He XL, Wang JH, Lv F, Hao Y, Liu MY, Yi Z*, Qiu WW*. Synthesis of novel diterpenoid analogs with in-vivo antitumor activity. Eur J Med Chem. 2016 May 2;120:13-25. (SCI,IF =3.5,通讯作者).,Siwko S,Zeng L,Li J,Yi Z,Liu M. Prostate- specificG-protein-coupled receptorcollaborateswithlossofPTENtopromoteprostatecancer progression. Oncogene. 2015 Jun 1. doi: 10.1038/onc.2015.170.年, Wang J, Lin L, He L, Wu Y, Zhang L, Yi Z, Chen Y, Pang X, Liu M. Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Mol Cancer Ther. 2012 Feb;11(2):277-87. 19. Wang X, Lin Q, Lv F, Liu N, Xu Y, Liu M, Chen Y*,Yi Z*. LG-362B targets PML-RARα and blocks ATRA resistance of acute promyelocytic leukemia. Leukemia. 2016 Jul; 30 (7): 1465- 74.(SCI,IF =12.104 通讯作者). 20. Li J, Zhai D, Lv F, Yu Q, Ma H, Yin J, Yi Z*, Liu M, Chang J, Wu C*. Preparation of copper- containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing. Acta Biomater. 2016 May; 36:254-66. (SCI,IF =6.025. 通讯作者).
