李春霞
近期热点
资料介绍
个人简历
李春霞,博士,华东师范大学心理与认知科学学院认知所副研究员。华东师范大学获理学博士学位(生理学),美国麻省理工学院大脑与认知科学系Mcgovern大脑研究所博士后。课题主要是综合利用多学科手段,整合分子生物学、遗传学、形态学、药理学和行为学等方法,主要研究记忆障碍的分子及细胞机制,以及精神疾病的发生机理。 主持的科研项目:上海市自然科学基金项目(20ZR1416600),2020-2023华东师范大学科研创新基金,2019-2020上海市自然科学基金项目(16ZR1410100),2016-2019国家自然科学基金项目(30800312),2009-2011教育部高等学校博士学科点专项科研新教师基金项目(20070269026),2008-2010上海高校选拔培养优秀青年教师科研专项基金(hsd-07029),2008-2009华东师范大学科研创新基金项目 2010-2011 参与的科研项目:国家863项目,2003-2007国家自然科学基金面上项目,2011-2013上海市科委科研计划项目,2011-2014 主讲和参讲课程:《学习记忆与可塑性》(主讲)、《认知神经科学概论》、《认知神经科学方法与技术》研究领域
1)脑疾病认知障碍的神经机制及调控 2)精神疾病中异常行为的发生机制 3)长期记忆再巩固的神经及环路机制""近期论文
(1). Beijun Wu, Chunxia Li, Huimeng Lei. SAPAP4 Deletion Causes Synaptic Dysfunction in the nucleus accumbens. Biochemical and Biophysical Research Communications. Biochemical and Biophysical Research Communications. 2018 Oct 12. pii: S0006-291X(18)32158-2. doi: 10.1016/j.bbrc.2018.10.016. [Epub ahead of print](2). Ting Cao, Xiaojuan Zhou, Xianjie Zheng, Yue Cui, Joe Z Tsien, Chunxia Li*, Huimin Wang*.Histone deacetylase inhibitor alleviates the neurodegenerative phenotypes and histone dysregulation in presenilins-deficient mice.Frontier in Aging Neuroscience. 2018;10:137. doi: 10.3389/fnagi.2018.00137. eCollection 2018.( *通讯作者)(3). Chunxia Li, Ning Zhang, Yinghe Hu, Huimin Wang. NR2B overexpression leads to the enhancement of specific protein phosphorylation in the brain. Brain Research. 2014. 1588:127-134(4). Chunxia Li, Men Su, Huimin Wang, Yinghe Hu. Global view of transcriptome in the brains of aged NR2B transgenic mice. Neural Regeneration Research. 2013.Volume 8,Number 29 2734-2743(5). Suzhen Dong1,Qingwen Zeng1, E.Siobhan Mitchell, Jin Xiu, Yale Duan1, Chunxia Li1, Jyoti K. Tiwari, Yinghe Hu, Xiaohua Cao, Zheng Zhao. Curcumin Enhances Neurogenesis and Cognition in Aged Rats: Implications for Transcriptional Interactions Related to Growth and Synaptic Plasticity. PloS One. 2012;7(2):e31211. doi: 10.1371/journal.pone.0031211. Epub 2012 Feb 16 (1 共同第一作者)(6). Chunxia Li, Suzhen Dong, Huimin Wang, Yinghe Hu. Microarray analysis of gene expression changes in the brains of NR2B-induced memory-enhanced mice. Neuroscience. 2011, 197: 121-131(7). Chunxia Li, Wenze Niu, Cecilia H. Jiang, Yinghe Hu. Effects of enriched environment on gene expression and signal pathways in cortex of hippocampal CA1 specific NMDAR1 knockout mice. Brain Research Bulletin 71 (2007) 568–577(8). Bing Mei1, Chunxia Li1, Suzhen Dong1, Cecilia H. Jiang, Huimin Wang, Yinghe Hu. Distinct gene expression profiles in hippocampus and amygdala after fear conditioning. Brain Research Bulletin 67:1–12, 2005. (1 共同第一作者)(9). Suzhen Dong, Chunxia Li, Pu Wu, Joe Z. Tsien, Yinghe Hu. Environment enrichment rescues the neurodegenerative phenotype in Presenilin-deficient mice. European Journal of Neuroscience 2007. 26(1):101-112, 2007.(10). Liyan Fang, Mancang Zhang, Chunxia Li, Suzhen Dong, Yinghe Hu. Chemical Genetic Analysis Reveals the Effects of NMU2R on the Expression of Peptide Hormones. Neuroscience Letters. 404:148–153, 2006.(11). 张宁,李春霞*.前脑特异性过表达NR2B基因对小鼠社会交往能力的影响 华东师范大学学报(自然科学版) 2012, 4:75-82(*通讯作者)(12). 李世佳,徐敏华,李春霞,周天舒,孟博,梅兵. 前脑特异性过表达NR2B基因对小鼠焦虑样行为无明显影响。生理学报。2009, 61 (3): 272-278.担任Neurobiology of learning and memory、Neuropharmcology、Journal of Neuroinflammation、Cellular and molecular life sciences、Neural Regeneration Research等杂志的审稿人 相关热点