个人简历

何德富，博士，副教授，研究室主任。1993年毕业于湖南师范大学生物系。1993年-1998年在南华大学从事教研工作。1998年-2003年在华东师范大学读硕士及博士研究生。2003年至今工作于华东师范大学生态与环境科学学院，主要从事微塑料等新型污染物、环境化学污染与毒理学方面研究。现课题组关注的重点在微塑料污染及其生态环境风险、固体废弃物及土壤污染治理等方面。2006年5月年到2007年9月在新加坡从事合作研究。近年来在国内外共发表论文40余篇。
所开主要课程：《环境生理与毒理学》，《环境与健康》
指导研究生名录：张贝、东春阳、王广鹤、许海燕、陈瑞瑞、蔡晓妍、陈娜、朱恩惠、刘梦芸、李嘉、杨永胜、李丹、徐天天、李平、吴思雨、雷丽丽、陆诗博、刘梦婷、宋杨、胡佳妮、邱荣、李昕羽、陈颖鑫、张晓婷。
已毕业研究生中多名获得国家奖学金、优秀毕业论文和优秀毕业生。欢迎环境科学、生物学等相关专业学生报考研究生。
科研项目
主持或参与国家重大科技专项、重点研发项目、自然基金等项目。
学术专著
Book

Microplastics in Terrestrial Environments
Emerging Contaminants and Major Challenges
Dr. Defu He, Dr. Yongming Luo in The Handbook of Environmental Chemistry(2020)

研究领域

"（1）微塑料污染与生态环境风险；
（2）固体废弃物及土壤修复；
（3）持久性有机污染物及毒理学机制。"

近期论文

Xinyu Li, Jiani Hu, Rong Qiu, Xiaoting Zhang, Yingxin Chen, Defu He*. Joint toxic effects of polystyrene nanoparticles and organochlorine pesticides (chlordane and hexachlorocyclohexane) on Caenorhabditis elegans.Environ. Sci.: Nano, 2020. https://doi.org/10.1039/D0EN00654H
Yang Song, Rong Qiu, Jiani Hu, Xinyu Li, Xiaoting Zhang, Yingxin Chen, Wei-MinWu*, Defu He*. Biodegradation and disintegration of expanded polystyrene by land snails Achatina fulica. Science of The Total Environment 2020, 746, 141289.
Weiwei Lv Quan Yuan Defu He Weiguang Lv Wenzong Zhou. Microplastic contamination caused by different rearing modes of Asian swamp eel (Monopterus albus). Aquaculture Research 2020, https://doi.org/10.1111/are.14847
Yingxin Chen, Yun Ling, Xinyu Li, Jiani Hua, Chengjin Cao, Defu He*. Size-dependent cellular internalization and effects of polystyrene microplastics in microalgae P. helgolandica var. tsingtaoensis and S. quadricauda. Journal of Hazardous Materials 2020, 399, 123092
Lu S, Qiu R, Hu J, Li X, Chen Y, Zhang X, Cao C, Shi H., Xie B, Wu W*, He Defu.* Prevalence of microplastics in animal-based traditional medicinal materials: Widespread pollution in terrestrial environments. Science of the Total Environment, 2020, 709.
Liu Mengting, Song Yang, Lu Shibo, Qiu Rong, Hu Jiani,Li Xinyu, Bigalke Moritz, Shi Huahong, He Defu*. A method for extracting soilmicroplastics through circulation of sodium bromide solutions. Science of TheTotal Environment, 2019, 691: 341-347.
Song Yang, Cao Chenjing, Qiu Rong, Hu Jiani, Liu Mengting, Lu Shibo, Shi Huahong, Raley-Susman KM, He Defu*. Uptake and adverse effects ofpolyethylene terephthalate microplastics fibers on terrestrial snails (Achatina fulica) after soil exposure. Environment Pollution. 2019. 250: 447-455.
Lv Weiwei, Zhou Wenzong, Lu Shibo, Huang Weiwei, Yuan Quan, Tian Minglu, Lv Weiguang*, He Defu*. Microplastic pollution in rice-fish co-culture system: A report of three farmland stations in Shanghai, China. Science of The Total Environment. 2019. 652: 1209-1218.（高被引）
He Defu*, Luo Yongming, Lu Shibo, Liu Mengting, Song Yang, Lei Lili. Microplastics in soils: analytical methods, pollution characteristics and ecological risks. Trends in Analytical Chemistry. 2018.109: 163-172.(封面论文，高被引)
Lei Lili, Wu Siyu, Lu Shibo, Liu Mengting, Song Yang, Fu Zhenhuan, Shi Huahong, Raley-Susman Kathleen M., He Defu*. Microplastic particles cause intestinal damage and other adverse effects in zebrafish Danio rerio and nematode Caenorhabditis elegans. Science of The Total Environment. 2018. 619-620: 1-8. (高被引和热点论文)
Liu Mengting, Lu Shibo, Song Yang, Lei Lili, Hu Jiani, Lv Weiwei, Zhou Wenzong, Cao Chengjin, Shi Huahong, Yang Xiaofeng, He Defu*. Microplastic and mesoplastic pollution in farmland soils in suburbs of Shanghai, China. Environmental Pollution. 2018. 242: 855-862. (高被引和热点论文)
Lei Lili, Liu Mengting, Song Yang, Lu Shibo, Hu Jiani, Cao Chengjin, Xie Bing, Shi Huahong, He Defu*. Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damages and other adverse effects in Caenorhabditis elegans. Environment Science: Nano. 2018. 5: 2009-2020.
Wu Siyu, Lei Lili, Liu Mengting, Song Yang, Lu Shibo, Li Dan, Shi Huahong, Raley-Susman Kathleen M., He Defu*. Single and mixture toxicity of strobilurin and SDHI fungicides to Xenopus tropicalis embryos. Ecotoxicology and Environmental Safety. 2018. 153: 8-15.
Wu Siyu, Lei Lili, Song Yang, Liu Mengting, Lu Shibo, Lou Dan, Shi Yonghong, Wang Zhibin*, He Defu*. Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism. Experimental Neurology. 2018. 309: 67-78.
Xu Tiantian, Zhang Manke, Hua Jiani, Li Zihan, Wu Taipu, Bao Jianing, WuSiyu, Lei Lili, He Defu*. Behavioral deficits and neural damage of Caenorhabditis elegans induced by three rare earth elements. Chemosphere. 2017. 181: 55-62.
Xu Tiantian, Li Ping, Wu Siyu, Lei Lili, He Defu*. Tris(2-chloroethyl) phosphate (TCEP) and tris(2-chloropropyl) phosphate (TCPP) induce locomotor deficits and dopaminergic degeneration in Caenorhabditis elegans. Toxicology Research. 2017, 6: 63-72.
Li Ping, Xu Tiantian, Wu Siyu, Lei Lili, He Defu*. Chronic exposure to graphene-based nanomaterials induces behavioral deficits and neural damages in Caenorhabditis elegans. Journal of Applied Toxicology. 2017, 37(10): 1140-1150.
Li Dan, Liu Mengyun, Yang Yongsheng, Shi Huahong, Zhou Junliang, He Defu*. Strong lethality and teratogenicity of strobilurins on Xenepus tropicalis embryo: basing on ten agricultural fungicides. Environmental Pollution. 2016, 208: 868-874.
Xu Tiantian, Li Ping, Wu Siyu, Li Dan, Wu Jingxuan, Raley-SusmanKathleen M., He Defu*. Chronicexposure to perfluorooctane sulfonate reduces lifespan of Caenorhabditiselegans through insulin/IGF-1 signaling. Bulletin of Environmental Contamination and Toxicology. 2016, 97: 119-123.
Li Jia, Li Dan, Yang Yongsheng, Xu Tiantian, Li Ping, He Defu*. Acrylamide induces locomotor defects and degeneration of dopamine neurons in Caenorhabditis elegans. Journal of Applied Toxicology, 2016, 36: 60-67.
Zhu Enhui, Chen Na, Liu MengYun, Li Jia, Li Dan, Yang Yongsheng, ZhangYing, He Defu*. Isomers and theirmetabolites of endosulfan induced cytotoxicity and oxidative damage in SH-SY5Ycells. Environmental Toxicology, 2016, 31(4): 496-504.
He Defu*, Chen Ruirui, Zhu Enhui, Chen Na, Shi Huahong, Huang Minsheng. Toxicity bioassays for water from black-odor rivers in Wenzhou, China. Environmental Science and Pollution Research, 2015, 22(3):1731-1741.
Chen Na, Li Jia, Li Dan, Yang Yongsheng, He Defu*. Chronic Exposure to Perfluorooctane Sulfonate Induces Behavior Defects and Neurotoxicity through Oxidative Damages, In Vivo and In Vitro. 2014, PLoS One, 9(11): e113453.
Xu Haiyan, Chen Ruirui, Cai Xiaoyan, He Defu*. Differential effects of activating D1 and D2 receptors on electrophysiology of neostriatal neurons in a rat model of Parkinson’s disease induced by paraquat and maneb. Neuroscience Research, 2011; 71(4): 411-20.
He Defu, Ma DL, Tang YC, Engel J, Bragin A, Tang FR*. Morpho-physiologic characteristics of dorsal subicular network in mice after pilocarpine- induced status epilepticus. Brain Pathology, 2010; 20(1): 80-95.
Environmental Science & Technology, Environment International, The Science of total environment, Environmental Pollution, Environmental Science: Nano, Nature Comunication, Scientific Reports, ES&T letters, Trends in Analytical Chemistry, Journal of Applied Toxicology, Environmental Science and Pollution Research, Ecotoxicology, Ecotoxicology and Environmental Safe, Neurotoxicity Research 等杂志长期审稿人。欧盟、国家自然科学基金、上海市科委等项目评审专家。