刘淑霞
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获奖:1、细胞因子在狼疮性肾炎发病中的作用及机制研究。河北省科技进步二等奖2018年第一完成人课题:TRIM27在狼疮性肾炎肾小球内皮细胞损伤中的作用、机制及其调控。国家自然科学基金面上项目(81970600),2020.1.1-2023.12.31,另:作为项目负责人完成国家自然科学基金项目1项,教育部新世纪优秀人才支持计划1项,教育部博士点基金项目1项,河北省杰出青年基金1项,省基金2项,其他省级、厅级课题10余项。近期论文
1HMGB1proteinpromotesglomerularmesangialmatrixviaTLR2inlupusnephritis.JCellPhysiol,2019,235(6):5111-5119.通讯作者。2KnockdownofTRIM27expressionsuppressesthedysfunctionofmesangialcellsinlupusnephritisbyFoxO1pathway.JCellPhysiol.2019;234(7):11555-11566.通讯作者3Anti-OSMantibodyinhibitstubulointerstitiallesioninamurinemodeloflupusnephritis.MediatorInflammation.2017;2017:3038514.通讯作者4RoleofPI3K/AktsignalpathwayonproliferationofmesangialcellinducedbyHMGB1.TissueCell.2016,48(2):121-125.通讯作者;5MiR-148a-3poverexpressioncontributestoglomerularcellproliferationbytargetingPTENinlupusnephritis.AmJPhysiolCellPhysiol.2016,310(6):C470-8.通讯作者6TLR2PlaysaCriticalRoleinHMGB1-InducedGlomeruliCellProliferationThroughtheFoxO1SignalingPathwayinLupusNephritis.JInterferonCytokineRes.2016,36(4):258-66,通讯作者。7PhosphorylationofPRAS40-Thr246involvesinrenallipidaccumulationofdiabetes.JCellPhysiol.2014;229(8):1069-77.通讯作者8ThePTEN/PI3K/AktsignalingpathwaymediatesHMGB1-inducedcellproliferationbyregulatingtheNF-κB/CyclinD1pathwayinmousemesangialcells.AmJPhysiolCellPhysiol,2014,306(12):C1119-28.第一作者9IFN-γinduceslipogenesisinmousemesangialcellsviatheJAK2/STAT1pathway.AmJPhysiolCellPhysiol,2013,304(8):c760-767.通讯作者10HMGB1mediatesIFN-γ-inducedcellproliferationinMMCcellsthroughregulationofcyclinD1/CDK4/p16pathway.JCellBiochem.2012,113(6):2009-2019.通讯作者11、High-fatdietcausesincreasedseruminsulinandglucosewhichsynergisticallyleadtorenaltubularlipiddepositionandextracellularmatrixaccumulation.BritJNutr,2012,107(1):74-85.通讯作者标签: 河北医科大学 河北医科大学基础医学院
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