个人简历

赵书林，博士，教授。湖南大学获学士学位，四川大学获博士学位，美国杰克逊州立大学访问学者（1999-2001年），俄罗斯莫斯科大学化学系合作研究（2013-2015年；2021-2022年）。2012-2016年任广西师范大学化学与药学学院院长。2011至今任化学与药学学院学术委员会主任，二级教授，博士生导师。是中国化学会有机分析专业委员会委员，曾担任国家自然科学基金委员会化学部专家评审组成员，国家自然科学基金重点项目、科学仪器专项、杰出青年基金、优秀青年基金项目评审和结题验收专家。在Science Advances,Chemical Science, Analytical Chemistry, Chem.Commun, Chemical EngineeringJournal, Biosensors and Bioelectronics, Advanced Healthcare Materials, ACSAppl. Mater. Interfaces, 中国科学-化学，等国内外学术期刊上发表学术论文400余篇，并被SCI引用8600余次，H指数47；获国家授权发明专利15项。参写中英文专著5部。负责制定国家标准2项。科研成果获广西自然科学奖一等奖3项，二等奖2项，三等奖1项。广西科技进步奖二等奖1项，三等奖1项。

研究领域

"""""1、单细胞分析新技术\r
2、生物传感新方法\r
3、生物成像新技术\r
1）光声成像探针的设计合成及应用\r
2）荧光成像探针的设计合成及应用\r
4、诊疗一体化纳米体系的设计和构建\r
5、药物靶向转运体系的设计和构建"

近期论文

Shulong Wang,Liangliang Zhang*, Jingjin Zhao, Min He, Yong Huang, Shulin Zhao*. A tumor microenvironment–induced absorption red-shifted polymernanoparticle for simultaneously activated photoacoustic imaging and photothermaltherapy. Science Advances, 2021, 7, eabe3588.（TOP期刊）\r
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Chaobang Zhang, Zhidong Qiu, LiangliangZhang,* Qiufang Pang, Zhengmin Yang, Jiang-Ke Qin, Hong Liang, Shulin Zhao.* Design and synthesisof a ratiometric photoacoustic imaging probe activated by selenol for visualmonitoring of pathological progression of autoimmune hepatitis. Chemical Science, 2021,12, 4883–4888.（TOP期刊）\r
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Jingjin Zhao,‡ Mengbing Zou,‡Mengjiao Huang, Liangliang Zhang, Keqin Yang, Shulin Zhao,* Yi-Ming Liu.*Amultifunctional nanoprobe for targeting tumors and mitochondria with singletoxygen generation and monitoring mitochondrion pH changes in cancer cells byratiometric fluorescence imaging Latexin deficiency attenuatesadipocyte differentiation and protects mice against obesity and metabolicdisorders induced by high-fat diet.Chemical Science, 2020,11, 3636–3643.（TOP期刊）\r
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Yulong Bai, Jingjin Zhao, LiangliangZhang*, Shulong Wang, Jing Hua, Shulin Zhao*,Hong Liang*. A Smart Near-Infrared Carbon Dot-Metal Organic Framework Assemblies forTumor Microenvironment-Activated Cancer Imaging and Chemodynamic-PhotothermalCombined Therapy, Adv. Healthcare Mater., 2022,2102759.（TOP期刊）\r
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Shulong Wang, Jingjin Zhao, LiangliangZhang*, Chaobang Zhang, Zhidong Qiu, ShulinZhao*. Yong Huang, Hong Liang*.A Unique Multifunctional Nanoenzyme Tailored for Triggering TumorMicroenvironment Activated NIR-II Photoacoustic Imaging and Chemodynamic/PhotothermalCombined Therapy. Adv. Healthcare Mater., 2021,2102073.（TOP期刊）\r
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Yulong Bai, Jingjin Zhao,* Shulong Wang,Tianran Lin, Fanggui Ye, Shulin Zhao*. Carbon Dots withAbsorption Red-Shifting for Two-Photon Fluorescence Imaging of Tumor Tissue pHand Synergistic Phototherapy. ACS Appl. Mater. Interfaces, 2021, 13, 35365−35375.\r
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Bingfang Shi, Yubin Su, LiangliangZhang,* Mengjiao Huang, Rongjun Liu, Shulin Zhao.* Nitrogen and PhosphorusCo-Doped Carbon Nanodots as a Novel Fluorescent Probe for Highly SensitiveDetection of Fe3+ in Human Serum and Living Cells.ACSAppl. Mater. Interfaces, 2016, 8,10717−10725. （TOP期刊）\r
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Zhidong Qiu,Chaobang Zhang, Liangliang Zhang,* Shulong Wang, Shengqiang Hu, Shulin Zhao.*Precise in VivoInflammation Imaging in the NIR-II Window Using 1065 nm Photoacoustic Probe forin Situ Visual Monitoring of Pathological Processes Related to Hepatitis. ACSSens., 2022,7, 641−648.（TOP期刊）\r
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ShengyuChen, Jingjin Zhao,* Ivan Yu Sakharov, Jiayao Xu, Chunhuan Xu, Shulin Zhao.* An ultrasensitivemultivariate signal amplification strategy based on microchip platform tailoredfor simultaneous quantification of multiple microRNAs in single cell, Biosensors and Bioelectronics, 2022, 203,114053. （TOP期刊）\r
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Chunhuan Xu, Jingjin Zhao,* ShengyuChen, Ivan Yu Sakharov, Shengqiang Hu, ShulinZhao.* An ultrasensitive bunge bedstraw herb type DNA machine for absolutequantification of mRNA in single cell.Biosensors and Bioelectronics, 2022, 217,114702.（TOP期刊）\r
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BingfangShi, YubinSu, Liangliang Zhang, RongjunLiu, MengjiaoHuang, Shulin Zhao.* Nitrogen-rich functional groupscarbon nanoparticles based fluorescent pH sensor with broad-range responding forenvironmental and live cells applications.Biosensors and Bioelectronics, 2016, 82,233–239.（TOP期刊）\r
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LiyunLin, Yuefang Hu, Liangliang Zhang*, Yong Huang, Shulin Zhao*. Photoluminescence light-up detection of zinc ion andimaging in living cells based on the aggregation induced emission enhancementof glutathione-capped copper nanoclusters. Biosensors and Bioelectronics, 2017, 94, 523–529.\r
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Guoxing Qin, Shulin Zhao,* Yong Huang, Jing Jiang, Yi-Ming Liu*. A sensitive goldnanoparticles sensing platform based on resonance energy transfer forchemiluminescence light on detection of biomolecules.Biosensors and Bioelectronics, 2013, 46, 119–123.（TOP期刊）\r
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ShulongWang, Liangliang Zhang,* Yanni Luo, Yulong Bai, Yong Huang, Shulin Zhao*. A Circular Dichroism and Photoacoustic Dual-Mode Probe for DetectionIn Vitro and Imaging In Vivo of Hydroxyl Radicals.Anal. Chem., 2022, 94, 2453−2464.（TOP期刊）\r
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Chaobang Zhang, Zhidong Qiu,Liangliang Zhang, Shulong Wang, ShulinZhao,* Qiufang Pang, Hong Liang*. Mitochondria-Targeted Fluorescence/ PhotoacousticDual-Modality Imaging Probe Tailored for Visual Precise Diagnosis ofDrug-Induced Liver Injury. Anal. Chem., 2022, 94, 6251−6260.（TOP期刊）\r
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Shengyu Chen, Jingjin Zhao, Chunhuan Xu,Ivan Yu. Sakharov, Shulin Zhao*. Absolute Quantification of MicroRNAs in a Single Cell with ChemiluminescenceDetection Based on Rolling Circle Amplification on a Microchip Platform. Anal. Chem., 2021, 93, 9218−9225.（TOP期刊）\r
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Chaobang Zhang,# RongkangGao,# Liangliang Zhang, Chengbo Liu,* Zhengmin Yang, Shulin Zhao*. Design and Synthesis of aRatiometric Photoacoustic Probe for In Situ Imaging of Zinc Ions in Deep TissueIn Vivo. Anal. Chem., 2020, 92, 6382−6390. （TOP期刊）\r
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Kun Hu, Yuanxia Lv, Fanggui Ye,* Tao Chen, Shulin Zhao*. Boric-Acid-Functionalized Covalent Organic Framework for Specific Enrichment and DirectDetection of cis-Diol-Containing Compounds by Matrix-Assisted LaserDesorption/Ionization Time-of-Flight Mass Spectrometry. Anal. Chem., 2019,91, 6353−6362. （TOP期刊）\r
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Rongjun Liu, Liangliang Zhang,* YunyunChen, Zirong Huang, Yong Huang, ShulinZhao*. Design of a New Near-InfraredRatiometric Fluorescent Nanoprobe for Real-Time Imaging of Superoxide Anionsand Hydroxyl Radicals in Live Cells and in Situ Tracing of the InflammationProcess in Vivo. Anal. Chem., 2018, 90, 4452−4460. （TOP期刊）\r
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Dongxia Chen, Jingjin Zhao, Liangliang Zhang,* RongjunLiu, Yong Huang, Chuanqing Lan, ShulinZhao*.Capsicum-DerivedBiomass Quantum Dots Coupled with Alizarin Red S as an Inner-Filter-MediatedIlluminant Nanosystem for Imaging of Intracellular Calcium Ions. Anal. Chem., 2018, 90, 13059−13064.（TOP期刊）