个人简历
姓名:王金全性别:男出生年月:1979.07学历（学位）:博士工作部门:生命科学与生物制药学院职务:无职称:副教授从事专业:生物制药招生专业:药学学习、工作经历（从大学阶段开始，按时间顺序写）1998.09-2003.07华北理工大学公共卫生学院本科，预防医学2003.09-2006.07华北理工大学公共卫生学院硕士，药物毒理学2011.09-2014.12中山大学化学学院博士，化学生物学2006.09-2008.12广东药科大学生命科学与生物制药学院助教2009.01-2019.08广东药科大学生命科学与生物制药学院讲师2019.01-至今广东药科大学生命科学与生物制药学院副教授目前承担项目1.主持国家自然科学基金面上项目(65万，2018.01.01-2021.12.31)：靶向肿瘤细胞线粒体的RGD肽偶联钌配合物的研究。(21771042)2.主持广东省科技计划项目(30万，2016.01.01-2018.12.31)：靶向肿瘤细胞线粒体的RGD肽-钌偶联药物临床前研究。(2015A020211037)3.主持广东省自然科学基金项目(10万，2016.06.01-2019.06.01)：具有靶向杀伤及显像双功能的NGR肽偶联钌配合物研究。(2016A030310298)4.主持广州市科技计划项目(20万，2016.04.01-2018.03.31)：靶向肿瘤细胞线粒体的RGD肽偶联钌配合物药理毒理学研究。(201607010087)
研究领域
主要研究方向：金属配合物抗肿瘤药理毒理学研究
近期论文
1.DanWang*,Jin-QuanWang*,Hai-EnHuang,Zi-ZhuoZhao,P.A.Gunatillake,Xiao-JuanHao*.Brush-shapedRAFTpolymermicellesasnanocarriersforaruthenium(II)complexphotodynamicanticancerdrug.Eur.Polym.J.,113:267-275,2019.(Co-CorrespondentAuthor,IF:3.7)2.Zi-ZhuoZhao1,Jia-YiWu1,Xiao-Di.Liu1,MingLiang,Xin-ChuanZhou,ShiOuyang,Ji-YiYao,Jin-QuanWang*,Bao-MingLuo*,Insufficientradiofrequencyablationpromotesproliferationofresidualhepatocellularcarcinomaviaautophagy.CancerLett,421:73-81,2018.(Co-CorrespondentAuthor,IF:6.3)3.KeLin,Zi-ZhuoZhao,Hua-BenBo,Xiao-JuanHao*,Jin-QuanWang*.Applicationsofrutheniumcomplexintumordiagnosisandtherapy,Front.Pharmacol.9:1323,2018.(Co-CorrespondentAuthor，IF:4.2)4.Kang-QiangQiu1,Jin-QuanWang1,T.W.Rees,Liang-NianJi,Qian-LingZhang*,HuiChao*.Amitochondria-targetingphotothermogenicnanozymeforMRI-guidedmildphotothermaltherapy.Chem.Commun.,54:14108,2018.(Co-FirstAuthor,IF:6.3)5.Jin-QuanWang*,Zi-zhuoZhao,ShuZhou,Xian-HuanZhang,Hua-BenBo*.Theantitumoreffectandtoxicityofaruthenium(II)complexinvivo.Inorg.Chem.Commun.,87:49-52,2018.(IF：1.6)6.Qiu-MiaoXiao1,Zi-ZhuoZhao1,KeLin,Jin-QuanWang*.Aphosphorescentcyclometalatediridium(III)complexasmitochondriatargetedtheranosticanticanceragent,Inorg.Chem.Commun.,94:75-79,2018.(IF：1.6)7.Jin-QuanWang*,Jun-FengKou,Zi-ZhuoZhao,Kang-QiangQiu,HuiChao*.Anthraquinone-bridgeddiruthenium(II)complexesinhibitmigrationandinvasionofhumanhepatocarcinomaMHCC97-Hcells,Inorg.Chem.Front.,4:1003-1012,2017.(IF：4.0)8.Jin-QuanWang*,Jun-FengKou,Xiao-JuanHou,Zi-ZhuoZhao,HuiChao*.Aruthenium(II)anthraquinonecomplexasthetheranosticagentcombininghypoxiaimagingandHIF-1ainhibition,Inorg.Chim.Acta.,345:176-183,2017.(IF：2.0)9.Ping-YuZhang1,Jin-QuanWang1,Huai-YiHuang,Kang-QiangQiu,Juan-JuanHuang,Liang-NianJi,HuiChao*.EnhancingthephotothermalstabilityandphotothermalefficacyofAuNRsandAuNTsbygraftingwithRu(II)complexes,J.Mater.Chem.B.,2017.(Co-FirstAuthor,IF：4.5)10.Kang-QiangQiu,Jin-QuanWang,Cui-LanSong,Li-LiWang,Hong-YiZhu,Huai-YiHuang,Juan-JuanHuang,HuiWang,Liang-NianJi,HuiChao*.CrossfireforTwo-PhotonPhotodynamicTherapywithFluorinatedRuthenium(II)Photosensitizers,ACSAppl.Mater.Interfaces,9,18482-18492,2017.(IF:7.5)11.Jin-QuanWang*,Xiao-JuanHou,Zi-ZhuoZhao,Hua-BenBo,Qi-ZhuChen.Acyclometalatediridium(III)complexthatinhibitsthemigrationandinvasionofMDA-MB-231cells.Inorg.Chem.Commun.,67:40-43,2016.(IF：1.6)12.Jin-QuanWang*,Xiao-juanHou,Cheng-zhiJin,HuiChao*.Acyclometalatediridium(III)complexservesasaphosphorescentprobeforspecificmitochondrialimaginginlivingcells,Chin.J.Chem.34:583-588,2016.(IF：1.8)13.Jin-QuanWang*,Zi-ZhuoZhao,Hua-BenBo,Qi-ZhuChen.Synthesis,characterization,andantitumorpropertiesofruthenium(II)anthraquinonecomplexes,J.Coord.Chem.,69,177-189,2016.(IF：1.8)14.Jin-QuanWang,Ping-YuZhang,Liang-NianJi,HuiChao*.Aruthenium(II)complexinhibitstumorgrowthinvivowithfewerside-effectscomparedwithcisplatin,J.Inorg.Biochem.,146:89-96,2015.(IF:3.2)15.Jin-QuanWang*,Xiao-JuanHou,Hua-BenBo,Qi-ZhuChen.Acyclometalatediridium(III)complexthatinducesapoptosisincisplatin-resistantcancercells,Inorg.Chem.Commun.,61:31-34,2015.(IF：1.7)16.Ping-YuZhang1,Jin-QuanWang1,Huai-YiHuang,Bo-LeYu,Kang-QiangQiu,Shu-TaoWang,LeiJiang,GillesGasser,Liang-NianJia,HuiChao*.Unexpectedhighphotothemalconversionefficiencyofgoldnanospheresupongraftingwithtwo-photonluminescentruthenium(II)complexes:Awaytowardscancertherapy?Biomaterials,63:102-114,2015.(Co-FirstAuthor,IF:8.3)17.Jin-QuanWang,Ping-YuZhang,ChenQian,Xiao-JuanHou,Liang-NianJi,HuiChao*.Mitochondriaaretheprimarytargetintheinductionofapoptosisbychiralruthenium(II)polypyridylcomplexesincancercells,J.Biol.Inorg.Chem.,19:335-348,2014.(IF:2.5)18.Ping-YuZhang1,Jin-QuanWang1,Huai-YiHuang,Hong-MingChen,Rui-LinGuan,YuChen,Liang-NianJi,HuiChao*.RuNH2@AuNPsastwo-photonluminescentprobesforthiolsinlivingcellsandtissues.Biomaterials,35,9003-9011,2014.(Co-FirstAuthor,IF:8.3)19.ChenQian,Jin-QuanWang,Cui-LanSong,Li-LiWang,Liang-NianJi*,HuiChao*.Theinductionofmitochondria-mediatedapoptosisincancercellsbyruthenium(II)asymmetriccomplexes.Metallomics,5:844-854,2013.(IF:3.5)20.Ping-YuZhang,Jin-QuanWang,Huai-YiHuang,Li-PingQiao,Liang-NianJi,HuiChao*.Chiralruthenium(II)complexeswithphenolichydroxylgroupsasdualpoisonsoftopoisomerasesIandIiα,DaltonTrans.,42:8907-8917,2013.(IF:3.8)21.Ping-YuZhang,Ling-MinPei,YuChen,Wen-ChaoXu,Qi-TianLin,Jin-QuanWang,Jing-HengWu,YongShen,Liang-NianJi,HuiChao*.Adinuclearruthenium(II)complexasaone-andtwo-photonluminescentprobeforbiologicalCu2+detection,Chem.Eur.J.,19:15494-15503,2013.(IF:5.7)22.Guan-YingLi,YuChen,Jin-QuanWang,QianLin,JingZhao,Liang-NianJi,HuiChao*.Adinucleariridium(III)complexasavisualspecificphosphorescentprobeforendogenoussulphiteandbisulphiteinlivingcells,Chem.Sci.,4:4426-4433,2013.(IF:9.2)23.Guan-YingLi,Ke-JieDu,Jin-QuanWang,Jie-WenLiang,Jun-FengKou,Xiao-JuanHou,Liang-NianJi,HuiChao*.Synthesis,crystalstructure,DNAinteractionandanticanceractivityoftridentatecopper(II)complexes,J.Inorg.Biochem.,119:43-53,2013.(IF:3.2)24.Jun-FengKou,ChenQian,Jin-QuanWang,XiangChen,Li-LiWang,HuiChao*,Liang-NianJi.Chiralruthenium(II)anthraquinonecomplexesasdualinhibitorsoftopoisomerasesIandII.J.Biol.Inorg.Chem.,17:81-96,2012.(IF:2.8)25.Ke-JieDu,Jin-QuanWang,Jun-FengKou,Guan-YingLi,HuiChao*,Liang-NianJi.Synthesis,DNA-bindingandtopoisomeraseinhibitoryactivityofruthenium(II)polypyridylcomplexes.Eur.J.Med.Chem.,46:1056-1065,2011.(IF:3.2)26.FengGao,XingChen,Jin-QuanWang,YuChen,HuiChao*,Liang-NianJi*.Invitrotranscriptioninhibitionbyruthenium(II)polypyridylcomplexeswithelectropositiveancillaryligands.Inorg.Chem.,48:5599-5601,2009.《Eur.J.Med.Chem.》,《Inorg.Chem.Commun.》,《J.Coord.Chem.》审稿人。
