个人简历

教育背景
2008-2010 香港理工大学应用生物与化学技术系、手性科学国家重点实验室（博士后）
2003-2008 中山大学药学院药物化学专业（硕博连读）（理学博士）
1999-2003 中山大学化工学院应用化学专业（理学学士）
工作经历
2011-至今 广东工业大学 副教授
2010-2011广东工业大学 讲师

研究领域

现主要研究方向为药物化学和有机化学；主要从事新靶点抗肿瘤药物的设计、合成和活性研究及药物作用分子机制研究，特别是天然药物的设计改造及其靶向抗肿瘤活性的研究；此外，也从事药物合成及工艺路线研究、生物传感器及化学生物学的研究。

近期论文

1. Yu-Jing Lu, Qiang Deng, Dong-Ping Hu,Zheng-Ya Wang, Bao-Hua Huang, Zhi-Yun Du, Yan-Xiong Fang, Wing-Leung Wong, KunZhang and Cheuk-Fai Chow, A molecular fluorescent dye for specific staining andimaging of RNA in live cells: a novel ligand integration from classicalthiazole orange and styryl compounds. Chem. Commun., 2015, 51, 15241-15244.（SCIⅡ区）
2. Yu-Jing Lu, Dong-Ping Hu, Qiang Deng,Zheng-Ya Wang, Bao-Hua Huang, Yan-Xiong Fang, Kun Zhang and Wing-Leung Wong,Sensitive and selective detection of uracil-DNA glycosylase activity with a newpyridinium luminescent switch-on molecular probe. Analyst, 2015,140, 5998-6004.（SCIⅡ区）
3. Yu-Jing Lu, Zheng-Ya Wang, Dong-Ping Hu, Qiang Deng,Bao-Hua Huang, Yan-Xiong Fang, Kun Zhang, Wing-Leung Wong, Cheuk-Fai Chow.Benzothiazole-substituted benzofuroquinolinium dyes as new fluorescent probesfor G-quadruplex DNA. Dyes and Pigments, 2015, 122, Pages 94–102.（SCIⅡ区）
4. Yu-Jing Lu, Wing-Leung Wong, Cheuk-FaiChow, A surfactant-like ionic liquid with permanganate dissolved as a highlyselective epoxidation system. Catalysis Communications, 2015, 69, 25–28.（SCI3区）
5. Jiaqiang Liu, Chang Sun, Wenliang Ma,Yu-Jing Lu, Lin Yu, Kun Zhang and Huaqiang Zeng, A conformationally switchablefluorescent oligophenol foldamer for selective sensing of copper(II) ions. RSCAdvances, 2014, 4, 54469-54473.
6. Sun N, Chan FY, Lu YJ, Neves MA, Lui HK,Wang Y, Chow KY, Chan KF, Yan SC, Leung YC, Abagyan R, Chan TH, Wong KY.Rational design of berberine-based FtsZ inhibitors with broad-spectrumantibacterial activity. PLoS One. 2014, 13, 9(5): e97514.
7. Wang HQ, Li DL, Lu YJ, Cui XX, Zhou XF,Lin WP, Conney AH, Zhang K, Du ZY, Zheng X. Anticancer activity of Acanthopanaxtrifoliatus (L) Merr extracts is associated with inhibition of NF-kB activityand decreased Erk1/2 and Akt phosphorylation. Asian Pac J Cancer Prev. 2014;15(21):9341-6.
8. Yue Wu, Li-Peng Zan, Xiao-Dong Wang,Yu-Jing Lu, Tian-Miao Ou, Jing Lin, Zhi-Shu Huang, Lian-Quan Gu, Stabilizationof VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives.Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840, 2970–2977. （SCIⅡ区）
9. Pan-Pan Wu , Kun Zhang, Yu-Jing Lu, PingHe, Su-Qing Zhao, In vitro and in vivo evaluation of the antidiabetic activityof ursolic acid derivatives. European Journal of Medicinal Chemistry, 2014, 80,502-508.
10. Chang Sun, Ying Liu, Jiaqiang Liu,Yu-Jing Lu, Lin Yu, Kun Zhang, and Huaqiang Zeng, Computational Insights intoProcesses Underlying the Amine-Induced Fluorescence Quenching of aStimuli-Responsive Phenol-Based Hexameric Foldamer Host. J. Org. Chem., 2014, 79, 2963–2973.（SCIⅡ区）
11. Bin Qiu, Ya-shan zhang, Yi-bing Lin,Yu-Jing Lu, Zhen-yu Lin, Kwok-Yin Wong, Guo-nan Chen, A novel fluorescentbiosensor for detection of target DNA fragment from the transgene cauliflowermosaic virus 35S promoter. Biosensors and Bioelectronics, Volume 41, 15 March2013, Pages 168–171. （SCI 1区）
12. Yi-Yong Yan, Jia-Heng Tan, Yu-Jing Lu,Siu-Cheong Yan, Kwok-Yin Wong, Ding Li, Lian-Quan Gu, Zhi-Shu Huang,G-Quadruplex conformational change driven by pH variation with potentialapplication as a nanoswitch. BBA - General Subjects, 2013, 1830, 4935-4942. （SCIⅡ区）
13. Yu-Jing Lu, Na Ma, Yu-jun Li, Zhen-yuLin, Bin Qiu, Guo-nan Chen, Kwok-Yin Wong. Styryl quinolinium/G-quadruplexcomplex for dual-channel fluorescent sensing of Ag+ and cysteine. Sensors andActuators B, 2012, 173, 295– 299.（SCIⅡ区）
14. Yu-Jing Lu, Siu-Cheong Yan, Fung-YiChan, Lan Zou, Wai-Hong Chung, Wing-Leung Wong, Bin Qiu, Ning Sun, Pak-Ho Chan,Zhi-Shu Huang, Lian-Quan Gu, and Kwok-Yin Wong. Benzothiazole-substitutedbenzofuroquinolinium dye: a selective switch-on fluorescent probe forG-quadruplex. Chemical Communication. 2011, 47, 4971-4973.（SCIⅡ区）
15. Yu-Jing Lu, Tian-Miao Ou, Jia-Heng Tan,Jin-Qiang Hou, Wei-Yan Shao, Dan Peng, Ning Sun, Xiao-Dong Wang, Wei-Bin Wu,Xian-Zhang Bu, Zhi-Shu Huang, Dik-Lung Ma, Kwok-Yin Wong, Lian-Quan Gu.5-N-Methylated Quindoline Derivatives as Telomeric G-Quadruplex StabilizingLigands: Effects of 5-N Positive Charge on Quadruplex Binding Affinity and CellProliferation. Journal of Medicinal Chemistry, 2008, 51, 6381-6392.（SCIⅡ区）
16. Tian-Miao Ou, Jing Lin, Yu-Jing Lu,Jin-Qiang Hou, Jia-Heng Tan, Shu-Han Chen, Zeng Li, Yan-Ping Li, Ding Li,Lian-Quan Gu, Zhi-Shu Huang, Inhibition of Cell Proliferation by QuindolineDerivative (SYUIQ-05) through its Preferential Interaction with c-myc PromoterG-Quadruplex, Journal of Medicinal Chemistry, 2011, 54, 5671–5679.（SCIⅡ区）
17. Bin Qiu, Zhen-Zhu Zheng, Yu-Jing Lu,Zhen-Yu Lin, Kwok-Yin Wong, Guo-Nan Chen, G-quadruplex DNAzyme as the turn onswitch for fluorimetric detection of genetically modified organisms, ChemicalCommunications, 2011, 47, 1437-1439.（SCIⅡ区）
18. Xiao-Dong Wang, Tian-Miao Ou, Yu-JingLu, Zeng Li, Zheng Xu, Lian-Quan Gu, Zhi-Shu Huang. Turning off transcriptionof the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindolinederivatives. Journal of Medicinal Chemistry, 2010, 53, 4390-4398.（SCIⅡ区）
19. Tian-Miao Ou, Yu-Jing Lu，Chi Zhang,Zhi-Shu Huang, Xiao-Dong Wang, Jia-Heng Tan, Yuan Chen, Dik-Lung Ma, Kwok-YinWong, Johnny Cheuk-On Tang, Albert Sun-Chi Chan , Lian-Quan Gu. Stabilizationof G-quadruplex DNA and down-regulation of oncogene c-myc by quindolinederivatives. Journal of Medicinal Chemistry, 2007, 50, 1465-1474. (Contributedequally with 1st author)（SCIⅡ区）
20. Jia-Heng Tan, Tian-Miao Ou, Jin-QiangHou, Yu-Jing Lu, Shi-Liang Huang, Hai-Bin Luo, Jian-Yong Wu, Zhi-Shu Huang, Kwok-Yin Wong, Lian-Quan Gu,Isaindigotone Derivatives: A New Class of Highly Selective Ligands forTelomeric G-Quadruplex DNA, Journal of Medicinal Chemistry, 2009, 52, 2825–2835.（SCIⅡ区）