个人简历

近年来，主持国家自然科学基金2项，主持省部级科研课题3项，科研累积经费80余万。以主要获奖人获得贵州省科技进步三等奖2项，贵州省医学会科技进步一等奖1项，三等奖1项。作为“贵州省特色天然药物资源活性研究科技创新团队”、“贵州省高等学科中药民族药系统研究与开发利用创新团队”及贵州医科大学“天然药物资源优效利用重点实验室”的核心技术骨干，参与了多个创新药物的药理毒理研究，中药创新药物评价。

研究领域

研究方向为心血管药理学、民族药药效物质基础及机制研究。

近期论文

1.Yanyan Zhang, Yuan Zhang, Jiayu Tang, Shuang Zhao, Chen Lia, Yongpan Huang, Minhan Yi.Oxymatrineinhibitss homocysteine-mediatedautophagy via MIF/mTORsignaling in human Umbilical Vein Endothelial cells. Cell PhysiolBiochem, 2018,45:1893-1903. 2018.3 2.Yan-Yan Zhang，Minhan Yi，Yongpan Huang. Oxymatrine Ameliorates DoxorubicinInduced Cardiotoxicity in Rats. Cell PhysiolBiochem, 2017,43:626-635. 2017.9 3.Tao-Li Sun, Zhi Liu, Zheng-Jun Qi, Yong-Pan Huang, Xiao-Qin Gao, Yan-Yan Zhang（通讯作者）. (-)-Epigallocatechin-3-gallate（EGCG）attenuates arsenin-induced cardiotoxicity in rats.Food and Chmical Toxicology, 93(2016):102-110. 4.Han XD, Yan-Yan Zhang,Wang KL,Huang YP,Yang ZB,Liu Z. The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO2-induced hepatotoxicity.Oncotarget,2017;8(39):65302-65312.doi:10.18632/oncotarget.18582. 5.Nenling Zhang, Birong Tian, Shuang Zhao, Xu Zhang, Di Pan, Xiangchun Shen，Yanyan Zhang. A new formylatedchalcone from Humuluslupulus with protective effect on HUVECs injury byangiotensin II. Natural Product Research,2017DOI:10.1080/14786419.2017.1402318.