个人简历
北京师范大学化学系学士（1995）、中国科学院上海药物研究所药物化学博士（2007）。曾师从中科院院士岳建民教授、中国工程院院士张伯礼教授以及代谢组学领域国际知名专家Oliver Fiehn 教授。主持国家自然科学基金3项，以及贵州省优秀青年科技人才专项资金、贵州省人民政府省长基金等10多个项目的研究；参与了民族药与中药开发应用教育部工程研究中心等多个教学科研平台的建设。主讲有《高等天然药物化学》等研究生课程。指导的学生发表SCI论文10余篇，获贵州省优秀硕士论文等奖项。目前已发表论文100余篇（论文被引用1100余次），其中SCI期刊论文50余篇，总影响因子超过150；申请专利26项，已获得专利7项。在化学类顶级期刊Chemical Reviews（最新影响因子52.613），Springer国际出版机构以第一作者身份撰写权威评论各一篇。
研究领域
中药、民族药的药效物质及其开发应用研究、中药及其他健康产品开发、药物代谢与代谢组学等。
近期论文
[1] Meng Zhou, Rui Li, Xiang-Ming Liao, Zheng Wang, Guo-Bo Xu, Zi-Peng Gong, Yuan Lu, Xun He, Yong-Jun Li, Yong-Lin Wang, Lin Zheng, Shang-Gao Liao*. Screening and analysis of potential active components in Shengxiong glucose injection using UHPLC coupled with photodiode array detection and MS/MS. Journal of Separation Science 2018, 41(10): 2130-2138. [2] Guo-Bo Xu, Yao-Hua Xiao, Qing-Yan Zhang, Meng Zhou, Shang-Gao Liao*. Hepatoprotective natural triterpenoids. European Journal of Medicinal Chemistry 2018, 145: 691-716. [3] Xiang-Ming Liao, Xun He, Guo-Bo Xu, Zhen Wang, Jing Li, Huan-Yu Guan, Meng Zhou, Yong-Jun Li, Yong-Lin Wang, Li-She Gan, Shang-Gao Liao*. Two Nitrogen-containing Compounds from Pseudostellaria heterophylla. Natural Product Communications 2018, 13(3): 343-346. [4] Xu Sun, Chengfen Yao, Dandan Xiong, Bao Zhang, Jia Sun, Shanggao Liao, Aimin Wang, Yanyu Lan, Yongjun Li. Simultaneous Quantification of Seven Caffeoylquinic Acids in Ecotypes of Blumea balsamifera at Various Life Stages by High-Performance Liquid Chromatography. Analytical Letters 2018, 51(11): 1642-1653. [5] Peng Liao, Shi-Qin Hu, Hong Zhang, Liang-Bi Xu, Jing-Zi Liu, Bin He, Shang-Gao Liao, Yong-Jun Li. Study on Anti-Proliferative Activity in Cancer Cells and Preliminary Structure–Activity Relationship of Pseudo-Peptide Chiral Thioureas. Bulletin of the Korean Chemical Society 2018, 39(3): 300-304. [6] Meng Zhou, Rong-Hong Zhang, Min Wang, Guo-Bo Xu, Shang-Gao Liao*. Prodrugs of triterpenoids and their derivatives. European Journal of Medicinal Chemistry 2017, 131: 222-236. [7] Meng Zhou, Min Wang, Rui-Feng Zhong, Xiang-Ming Liao, Lian-Li Deng, Guo-Bo Xu, Xun He, Jing Li, Yong-Jun Li, Ting Liu, Yong-Lin Wang, Shang-Gao Liao*. Discovery and structure-activity relationship of auriculatone: A potent hepatoprotective agent against acetaminophen-induced liver injury. Bioorganic & Medicinal Chemistry Letters 2017, 27(16): 3636-3642. [8] Guo-Bo Xu Min Wang, Jun Liu, Yue-Hao Zhang, Jun-Hong Liu, Jing Li, Meng Zhou, Yao-Hua Xiao, Xun He, Shang-Gao Liao. Buxusoside, a Flavonoid Disaccharide from Buxus sinica. Natural Product Communications 2017, 12(4): 525-526. [9] Yong Huang, Hui-Yuan Sun, Xiao-Li Qin, Yong-Jun Li, Shang-Gao Liao, Zi-Peng Gong, Yuan Lu, Yong-Lin Wang, Ai-Min Wang, Yan-Yu Lan, Lin Zheng. A UPLC-MS/MS Method for Simultaneous Determination of Free and Total Forms of a Phenolic Acid and Two Flavonoids in Rat Plasma and Its Application to Comparative Pharmacokinetic Studies of Polygonum capitatum Extract in Rats. Molecules 2017, 22(3): 353. [10] Huan-yu Guan, Peng-fei Li, Xiao-ming Wang, Jia-jing Yue, Yang He, Xiao-mei Luo, Mei-feng Su, Shang-gao Liao, Yue Shi. Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity. Frontiers in Pharmacology 2017, 8(769). [11] Huanyu Guan, Xiaoming Wang, Shiping Wang, Yang He, Jiajing Yue, Shanggao Liao, Yuanda Huang, Yue Shi. Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample preparation and LC-MS/MS. RSC Advances 2017, 7(69): 43621-43635. [12] Dong-Hua Cao, Shang-Gao Liao, Lin Yang, Xiao-Nian Li, Bin Wu, Ping Zhang, Juan Guo, Chun-Fen Xiao, Hua-Bin Hu, You-Kai Xu. Trichiliasinenoids A–C, three 6,7-secomexicanolide limonoids with a 7,29-linkage from Trichilia sinensis. Tetrahedron Letters 2017, 58(33): 3283-3286. [13] Shang-Gao Liao, Jian-Min Yue, Dimeric Sesquiterpenoids. In Progress in the Chemistry of Organic Natural Products 101, A. D. Kinghorn,H. Falk,S. Gibbons,J. i. Kobayashi, Eds. Springer International Publishing: Cham, 2016; pp 1-112. [14] Kai-Long Ji, Xiao-Nian Li, Shang-Gao Liao, Hua-Bin Hu, Ren Li, You-Kai Xu. Cytotoxic limonoids from the leaves of Walsura robusta. Phytochemistry Letters 2016, 15: 53-56. [15] Huan-Yu Guan, Yan Yan, Yong-Lin Wang, Ai-Min Wang, Jun-Hong Liu, Xun He, Yong-Jun Li, Yong Huang, Shang-Gao Liao*. Isolation and characterization of two new 2-isobutylmalates from Bletilla striata. Chinese Journal of Natural Medicines 2016, 14(11): 871-875. [16] Li Cheng, Kai-long Ji, Shang-gao Liao, Li-she Gan, Lin Yang, Dong-hua Cao, Ying-qian Liu, Juan Guo, Ping Zhang, Chuan-li Lu. Diterpenoids and phenanthrenones from the leaves and stems of Strophioblachia fimbricalyx. Tetrahedron Letters 2016, 57(21): 2262-2265. [17] Rui-Feng Zhong, Guo-Bo Xu, Zheng Wang, Ai-Min Wang, Huan-Yu Guan, Jing Li, Xun He, Jun-Hong Liu, Meng Zhou, Yong-Jun Li, Yong-Lin Wang, Shang-Gao Liao*. Identification of anti-inflammatory constituents from Kalimeris indica with UHPLC-ESI-Q-TOF-MS/MS and GC-MS. Journal of Ethnopharmacology 2015, 165: 39-45. [18] Ya-Xin Yang, Ai-Min Wang, Zheng Wang, Yong-Lin Wang, Jin Zhang, Jun-Hong Liu, Xun He, Yong-Jun Li, Xiao-Yan Hao, Shang-Gao Liao*. Chemical Fingerprinting and Multi-marker Determination of the Roots of Indigofera stachyoides by UHPLC-Q-TOF/MS. Current Pharmaceutical Analysis 2015, 11(4): 260-268. [19] You-Kai Xu, Lin Yang, Shang-Gao Liao, Pei Cao, Bin Wu, Hua-Bin Hu, Juan Guo, Ping Zhang. Koumine, humantenine, and yohimbane alkaloids from Gelsemium elegans. Journal of Natural Products 2015, 78(7): 1511-1517.
