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巩仔鹏
2023-05-10 11:26
  • 巩仔鹏
  • 巩仔鹏 - 教授-贵州医科大学-药学院-个人资料

近期热点

资料介绍

个人简历


2011年9月进入中国中医科学院中药研究所攻读博士学位,并于2014年7月博士毕业,获医学博士学位;同年9月进入贵州医科大学贵州省药物制剂重点实验室从事科研工作,同时在贵州医科大学药学院药剂学教研室承担本科生《药剂学》、《生物药剂学与药物动力学》以及研究生《高等药物动力学》、《药物转运体基础与应用》、《高等生物药剂学与药物动力学》的教学工作; 现为贵州医科大学贵州省药物制剂重点实验室药物代谢与代谢毒理学研究室副主任,先后被评为贵州医科大学高层次人才(第四层次)、青年骨干教师,同时也是河北省科技奖励通讯评审专家、贵州省科技厅项目通讯评审专家、贵州省卫生和计划生育委员会项目通讯评审专家。

研究领域


中药药代动力学及其PK-PD(药动学-药效学)结合模型的建立。

近期论文


(1) Siying Chen#,Mei Li#,Yueting Li,Hejia Hu,Ying Li,Yong Huang,Lin Zheng,Yuan Lu,Jie Hu,Yanyu Lan,Aimin Wang,Yongjun Li,Zipeng Gong*,Yonglin Wang*. A UPLC-ESI-MS/MS Method for Simultaneous Quantitation of Chlorogenic Acid, Scutellarin, and Scutellarein in Rat Plasma: Application to a Comparative Pharmacokinetic Study in Sham-Operated and MCAO Rats after Oral Administration of Erigeron breviscapus Extract. Molecules. 2018, 23(7), pii: E1808. (2) Guangcheng Wang*, Zhiyun Peng, Jiebing Zhang, JieQiu, Zhenzhen Xie, Zipeng Gong*. Synthesis, biological evaluation and molecular docking studies of aminochalcone derivatives as potential anticancer agents by targeting tubulin colchicine binding site. Bioorganic Chemistry. 2018, 78:332-340. (3) Zipeng Gong#, Ying Chen#, Ruijie Zhang, et al. Pharmacokinetic Difference of Berberine between Normal and Chronic Visceral Hypersensitivity Irritable Bowel Syndrome Rats and its mechanism. Archives of Pharmacal Research. 2015, 38(10): 1888-1896. (4) Zipeng Gong, Ying Chen, Ruijie Zhang, et al. Pharmacokinetic Comparison of Berberine in Rat Plasma after Oral Administration of Berberine hydrochloride in Normal and post Inflammation Irritable Bowel Syndrome Rats. International Journal of Molecular Sciences. 2014, 15(1):456-467. (5) Zipeng Gong#, Ying Chen#, Ruijie Zhang, et al. Pharmacokinetics of two Alkaloids after Oral Administration of RhizomaCoptidis Extract in Normal Rats and Irritable Bowel Syndrome Rats. Evidence-Based complementary and alternative medicine. 2014, doi: 10.1155/2014/845048.

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