个人简历

教育工作经历：1992/09 - 1995/07 中山大学医学院麻醉专业硕士导师：陈秉学；1985/09 - 1990/07 江西医学院医疗系获学士；2009/11 -至今广州医科大学附属广州市妇女儿童医疗中心，麻醉科主任，主任医师，教授，硕士生导师；1995/7 -2009/11 广东省人民医院心血管病研究所，麻醉科，主任医师；2006 年到美国麻省总医院和波士顿儿童医院参观学习。
正在承担的与本项目相关的科研项目情况：
1. 申请人承担的课题项目： 81671116 ， 国家自然科学基金面上基金项目 NRG1-ErbB4 信号介导的NMDA 受体紊乱在七氟醚神经毒性中的作用和机制研究， 2017/01- 2020/12，59 万元，在研，主持
2. 主要参与人承担的课题项目：国家自然科学基金青年科学基金项目，81503172，母体七氟醚暴露致子代情绪障碍：突触粘附分子β-neurexin/neuroligin 1 的作用及机制，2016/01- 2018/12，17.9 万元，在研，第一参与人
3. 申请人承担的课题项目：广东省自然科学基金项目，2014A030313648，Alpha2受体激动剂抑制谷氨酸分泌降低利多卡因神经毒性机制研究，2014/10/01-2017/10/01, 10 万元，在研，主持
4. 申请人承担的课题项目：广东省承担政府特定任务项目，2011B061200001，钙振荡在七氟醚影响胎鼠海马神经元树突棘发育中的作用,2011/10/01 -2013/10/01, 5 万元，已结题，主持专利：共获得5项专利
一种椎管内麻醉剂及其制备方法和应用，2015年，应用型，专利号：ZL 201510187623.9
一种人体气管气压测量装置，2015年，发明型，专利号：201520523068.8
一种基于食道封堵胃肠减压的通气装置，2016年，应用型，专利号：201620349827.8
一种医用食道导管及其制备方法和通气装置，2017年，应用型，专利号：2016108825919
一种椎管内麻醉剂及其制备方法及应用，2017年，发明型，专利号：2015101876239

研究领域

小儿麻醉及神经保护。

近期论文

1: Li BL, Zhang N, Song X*. Intranasal dexmedetomidine with and without buccal midazolam for procedural sedation in autistic children: a double-blind randomised controlled trial.The Lance. t2017 Dec;Volume 390, Special Issue, S26.
2：Zhao B, Pan Y, Xu H, Song X*. Hyperbaric oxygen attenuates neuropathic pain and reverses inflammatory signaling likely via the Kindlin-1/Wnt-10a signaling pathway in the chronic pain injury model in rats. J Headache Pain. 2017 Dec;18(1):1. doi: 10.1186/s10194-016-0713-y. Epub 2017 Jan 5. PubMed PMID:28058534; PubMed Central PMCID: PMC5216011.
3: Zhao B, Pan Y, Wang Z, Xu H, Song X*. Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via p38 Mitogen-Activated Protein Kinase in a Rat Model. Yonsei Med J. 2017 Jan;58(1):131-138. doi:10.3349/ymj.2017.58.1.131. PubMed PMID: 27873505.
4: Zhang W, Fan Y, Zhao T, Chen J, Zhang G, Song X*. Median Effective Dose of Intranasal Dexmedetomidine for Rescue Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging. Anesthesiology. 2016 Dec;125(6):1130-1135. PubMed PMID: 27627818.
5:Zhao B, Pan Y, Wang Z, Tan Y, Song X*. Intrathecal Administration of Tempol Reduces Chronic Constriction Injury-Induced Neuropathic Pain in Rats by Increasing SOD Activity and Inhibiting NGF Expression. Cell Mol Neurobiol. 2016 Aug;36(6):893-906. doi: 10.1007/s10571-015-0274-7. Epub 2015 Oct 3. PubMed PMID: 26433732.
6: Zhao T, Li C, Wei W, Zhang H, Ma D, Song X*, Zhou L. Prenatal ketamine exposure causes abnormal development of prefrontal cortex in rat. Sci Rep. 2016 May 26;6:26865. doi: 10.1038/srep26865. PubMed PMID: 27226073; PubMed Central PMCID: PMC4881038.
7: Li BL, Zhang N, Huang JX, Qiu QQ, Tian H, Ni J, Song XR*, Yuen VM, Irwin MG. A comparison of intranasal dexmedetomidine for sedation in children administered either by atomiser or by drops. Anaesthesia. 2016 May;71(5):522-8. doi:10.1111/anae.13407. PubMed PMID: 26936022.
8: Tian H, Hou L, Xiong YM, Huang JX, Zhang WH, Pan YY, Song XR*. miR-132 targeting E2F5 suppresses cell proliferation, invasion, migration in ovarian cancer cells. Am J Transl Res. 2016 Mar 15;8(3):1492-501. PubMed PMID: 27186275; PubMed Central PMCID: PMC4859634.
9: Zhang W, Wang Z, Song X*, Fan Y, Tian H, Li B. Comparison of rescue techniques for failed chloral hydrate sedation for magnetic resonance imaging scans--additional chloral hydrate vs intranasal dexmedetomidine. Paediatr Anaesth. 2016 Mar;26(3):273-9. doi: 10.1111/pan.12824. PubMed PMID: 26714442.
10: Chen JH, Yu GF, Jin SY, Zhang WH, Lei DX, Zhou SL, Song XR*. Activation of α2 adrenoceptor attenuates lipopolysaccharide-induced hepatic injury. Int J Clin Exp Pathol. 2015 Sep 1;8(9):10752-9. PubMed PMID: 26617786; PubMed Central PMCID:PMC4637601.
11:Li BL, Ni J, Huang JX, Zhang N, Song XR*，Yuen VM. Intranasal dexmedetomidine for sedation in children undergoing transthoracic echocardiography study--a prospective observational study. Paediatr Anaesth. 2015 Sep;25(9):891-6. doi:10.1111/pan.12687. Epub 2015 May 9. PubMed PMID: 25959165.
12: Zhao BS, Song XR*, Hu PY, Meng LX, Tan YH, She YJ, Ding YY. Hyperbaric oxygen treatment at various stages following chronic constriction injury produces different antinociceptive effects via regulation of P2X4R expression and apoptosis. PLoS One. 2015 Mar 19;10(3):e0120122. doi: 10.1371/journal.pone.0120122. PubMed PMID: 25789619; PubMed Central PMCID: PMC4366063.
13: She YJ, Wang HZ, Huang JX, Tan YH, Wang ZX, Tian H, Song XR*. Effect of a bolus dose of fentanyl on the ED50 and ED95of sevoflurane in neonates. Med Sci Monit. 2014 Dec 14;20:2658-65. doi: 10.12659/MSM.891276. PubMed PMID: 25503557; PubMedCentral PMCID: PMC4271805.
14: Tian H, Hou L, Xiong YM, Huang JX, She YJ, Bi XB, Song XR*. miR-218 suppresses tumor growth and enhances the chemosensitivity of esophageal squamous cell carcinoma to cisplatin. Oncol Rep. 2015 Feb;33(2):981-9. doi:10.3892/or.2014.3657. PubMed PMID: 25482044.
15: She YJ, Xie GT, Tan YH, Kuang XH, Yu GF, Lian GH, Song XR*. A prospective study comparing the onset and analgesic efficacy of different concentrations of levobupivacaine with/without dexmedetomidine in young children undergoing caudal blockade. J Clin Anesth. 2015 Feb;27(1):17-22. doi:10.1016/j.jclinane.2014.09.005. PubMed PMID: 25468576.
16: She YJ, Zhang ZY, Song XR*. Caudal dexmedetomidine decreases the required concentration of levobupivacaine for caudal block in pediatric patients: a randomized trial. Paediatr Anaesth. 2013 Dec;23(12):1205-12. doi:10.1111/pan.12278. PubMed PMID: 24383602.
中华医学会第十二届麻醉分会小儿学组副组长，中国医师协会麻醉学分会第五届常务委员，广东省医师协会麻醉学分会第四届主任委员，广东省医学会麻醉学分会第十届副主任委员，广东省医学会第6届常务委员，广东省妇幼保健协会麻醉与镇痛专业委员会第一届副主任委员，广东省麻醉医疗质量控制中心专家，广东和谐医患纠纷人民调解委员会医学专家顾问，“中华麻醉学杂志”第十一届编委会编委，“临床麻醉学杂志”第九届编委会通讯编委。曾多次担任广东省高级职称评审委员会专家。