个人简历

曾军，男，41岁，广州医科大学遗传细胞教研室教研人员；化学致癌所研究人员。具体研究方向是对肿瘤表达的特异或相关抗原对肿瘤微环境中的间质细胞如MSCs、TAMs和TADCs的表型影响进行探索；对MSCs及免疫细胞在化学致癌肿瘤微环境中的分化及在肿瘤间质建成中的作用和分子机制进行探索。意欲从中发现药物作用的特异靶点，并在微环境水平研究生物靶向治疗的可能性。

研究领域

肿瘤表达的特异或相关抗原对肿瘤微环境中的间质细胞如MSCs、TAMs和TADCs的表型影响进行探索；对MSCs及免疫细胞在化学致癌肿瘤微环境中的分化及在肿瘤间质建成中的作用和分子机制进行探索。意欲从中发现药物作用的特异靶点，并在微环境水平研究生物靶向治疗的可能性。"肿瘤微环境及相关生物靶向药物研制；苯并芘致癌与肿瘤微环境关系"

近期论文

（1）Jun Zeng, Shaohui Cai, Yanmei Yi, Yuwen He, Zhen Wang, Guanmin Jiang, Xiaokun Li, Jun Du. Prevention of spontaneous tumor development in a ret transgenic mice model by Ret peptide vaccination with Indoleamine 2, 3-dioxygenase inhibitor, 1MT. Cancer Research. 2009 May; 69: (9): 3963-3970. (IF: 8.234)
（2）Jun Du, Jun Zeng, Xueling Ou, Xianda Ren, Shaohui Cai. Methylglyoxal downregulates Raf-1 protein through a ubiquitination-mediated mechanism. Int J Biochem Cell Biol. 38(7):1084-1091. 2006. (IF: 4.956)
（3）Guanmin Jiang, Yuwen He, Rui Fang, Ge Zhang, Jun Zeng, Yanmei Yi, Shu Zhang, Xianzhang Bu, Shaohui Cai, Jun Du. Sodium butyrate down-regulation of indoleamine 2, 3-dioxygenase at the transcriptional and post-transcriptional levels. Int J Biochem Cell Biol. 2010 Nov;42(11):1840-1846. Epub 2010 Aug. (IF: 4.956)
（4）Yanmei Yi, Ge Zhang, Jun Zeng, Sichao Huang, Lingling Li, Rui Fang, Guanmin Jiang, Xianzhang Bu, Shaohui Cai, Jun Du. A new tumor vaccine FAPτ-MT elicits effective antitumor response by targeting indolamine-2,3-dioxygenase in antigen presenting cells. Cancer Biology & Therapy. 2011 May 15, 11(10):1-8.(IF: 2.907)
（5）Xueling Ou, Shaohui Cai, Peng Liu, Jun Zeng, Jun Du. Enhancement of dendritic cell-tumor fusion vaccine potency by indoleamine-pyrrole 2,3-dioxygenase inhibitor, 1-MT. J Cancer Res Clin Oncol; 2008 May;134(5): 525-533. (IF: 2.485)