林翔
近期热点
资料介绍
个人简历
教育工作经历:2000-2004 年 厦门大学 学士学位2004-2010年 厦门大学 博士学位2008-2010 年 美国休斯顿 Institute of Biosciences and Technology, Health Science Center, Texas A&M University 进修,从事 FGF 信号通路研究。2010年-至今 福州大学 助理研究员教学简介:本科生《生物化学》、《无机与分析化学》主讲教师。研究生专业课《实验动物学》主讲教师。 科研简介:主持2项福州大学科技发展基金,参与国家自然科学基金委面上项目1项,青年基金1项,省自然科学基金1项。目前已在 Development,European Journal of Organic Chemistry,International Journal of Biological Sciences, Circulation Research等国际杂志上发表过多篇 SCI 文章。 科研项目:参与课题 1、福州大学科技发展基金《小鼠干细胞分化为黑色素细胞的研究》2、福州大学科技发展基金《小鼠胚胎干细胞早期分化的细胞信号网络分析》3、国家自然科学基金青年项目《化疗脱发中p53对Sonic Hedgehog信号通路调控机制研究》4、福建省自然科学基金《Shh信号通路在化疗引起的脱发中的作用及其机制研究》5、国家自然科学基金面上项目《非经典Wnt信号途径调控羽毛细胞形状及形态构建》研究领域
发育生物学,主要研究方向包括干细胞分化及羽毛发育研究。""近期论文
代表性论文:(*为通讯作者)1、Lin, X. , Gao,Q, , Zhu,L. , Zhou, G.,Ni, S , Han, H. and Yue, Z. Long non-coding RNAs regulate Wnt signaling during feather regeneration. Development 2018, 145 (21): dev1623882、Lin, X., Zhang, Y., Liu, L., McKeehan, W.L., Shen, Y., Song, S. and Wang, F. . FRS2α is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts. International Journal of Biological Sciences 2011, 7(8):1114-1121. 3、Lin, T., Lin, X.(co-first author), Lu, C., Hu, Z., Huang, W., Huang, Y. and Shen, Y. . Secondary metabolites of Phomopsis sp. XZ-26, an endophytic fungus from Camptotheca acuminate. European Journal of Organic Chemistry 2009, 2009(18):2975-2982 .4、Yuan, L., Lin, X.(co-first author), Zhao, P., Ma, J., Huang, Y. and Shen, Y. . New polyketides from endophytic Diaporthe sp. XZ-07. Helvetica Chimica Acta 2009, 92(6):1184-1190.5、Lin, X., Lu, C., Huang, Y., Zheng, Z., Su, W. and Shen, Y.. Endophytic fungi from a pharmaceutical plant, Camptotheca acuminata: isolation, identification and bioactivity. World Journal of Microbiol and Biotechnology 2007, 23(7):1037–1040. 6、林翔, 周桂炫, 陈菲,黄炜娟,乐志操. 色素细胞发育分化的分子调控机制. 福州大学学报(自然科学版)2011. 39(5):649-657. 7、Chen X., Liao C., Chu Q., Zhou G., Lin X., Li X., Lu H., Xu B., Yue Z.. Dissecting the Molecular Mechanism of Ionizing Radiation-Induced Tissue Damage in the Feather Follicle. Plosone 2014, 10.1371/journal.pone.0089234. 8、Chu Q, Cai L, Fu Y, Chen X, Yan Z, Lin, X., Zhou G, Han H, Widelitz RB, Chuong CM, Wu W, Yue Z. Dkk2/Frzb in the dermal papillae regulates feather regeneration. Dev Biol. 2014,387(2):167-78. 9、Liu, Y., Hu, Z. Lin, X. Lu, C. Shen, Y. . A new polyketide from Diaporthe sp. SXZ-19, an endophytic fungal strain of Camptotheca acuminate. Nat Prod Res 2013, 27(22):2100-2104. 10、Lin, T., Wang, G., Lin, X., Hu, Z., Chen, Q., Xu, Y., Zhang, X. and Chen, H. Three new oblongolides from Phomopsis sp. XZ-01, an endophytic fungus from Camptotheca acuminate. Molecules, 2011, 16, 3351-3359. 11、Zhang, J., Chang, J. Y, Huang, Y., Lin, X., Luo, Y., Schwartz, R. J., Martin, J. F. and Wang, F. . The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. Circulation Research 2010, 107(10): 1209-1219. 12、Lu, C., Lin, X. and Shen, Y. . A new dihydroisocoumarin from the strain A spergillus sp. CMM, an endophytic fungus of Cephalotaxus mannii. Chemistry of Natural Compounds (Impact Factor: 0.5). 2008, 44(5):569-571. 13、Tan, Q., Yan, X., Lin, X., Huang, Y., Zheng, Z., Song, S., Lu, C. and Shen, Y. . Chemical Constituents of the Endophytic Fungal Strain Phomopsis sp. NXZ-05 of Camptotheca acuminata. Helvetica Chimica Acta 2007, 90(9):1811-1817. 相关热点