个人简历

教育经历：
2019年6月 至今 福州大学 生物科学与工程学院
美国加州理工学院 Caltech | Biochemistry and Molecular Biophysics |博士
厦门大学 | 生物技术 | 学士

教学简介：
主要承担《生物化学》、《合成生物技术》、《系统生物工程》等课程的教学任务。

Our group mainly focuses on prototyping and building novel biological circuits in both cell-free systems and cells, and using synthetic biology tools to advance the discovery of new enzymes. We are interested in utilizing cell-free systems to assist the research in synthetic biology by performing fast prototyping on biological parts and modules, with the goals of building novel biological circuits and metabolic pathways to tackle various problems.
在研项目：
1. 国家自然科学基金青年科学基金项目：利用无细胞转录翻译系统和生物回路实现植物糖基转移酶的高通量研究（2020年-2023年）
2. 福建省中青年教师教育科研项目：制备用于合成生物学研究的高效无细胞转录表达体系（2019年-2022年）

研究领域

合成生物学，生物工程，分子生物学"主要研究领域为：
（1）无细胞转录翻译系统 Cell-free transcription-translation systems；
（2）基因回路与生物探测器 Genetic circuits and biosensors；
（3）蛋白质高通量表达和筛选 High-throughput screening of proteins/enzymes."

近期论文

代表性论著：
1. Wei, Z.; Shi, X.; Lian, R.; Wang, W.; Hong, W.; Guo, S., Exclusive Production of Gentamicin C1a from Micromonospora purpurea by Metabolic Engineering. Antibiotics (Basel) 2019, 8 (4).
2. Guo, S.; Murray, R. M., Construction of Incoherent Feedforward Loop Circuits in a Cell-Free System and in Cells. ACS Synth Biol 2019, 8 (3), 606-610.
3. Vaish, A.; Guo, S.; Murray, R. M.; Grandsard, P. J.; Chen, Q., On-chip membrane protein cell-free expression enables development of a direct binding assay: A curious case of potassium channel KcsA-Kv1. 3. Analytical Biochemistry 2018, Volume 556, 70-77.
4. Vaish, A.; Chen, C.; Guo, S., Cell-free expression of biologically active integral membrane protein. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017; Vol. 253.
5. Guo, S.; Hori, Y.; Murray, R., Systematic design and implementation of a novel synthetic fold-change detector biocircuit in vivo. 2015 Winter Q-Bio Conference 2015.
6. Yeung, E.; Guo, S.; Murray, R. M., System identification of the phosphorylation based insulator in an in vitro cell-free expression system. 2014 Winter Q-bio Conference 2014.
7. Guo, S.; Yeung, E.; Nilgiriwala, K. S.; Del Vecchio, D.; Murray, R. M., Implementation And Simulation Of Phosphorylation-Based Insulator In Transcription-Translation Platform. In 2014 Winter Q-bio Conference, 2014.