严海丹
近期热点
资料介绍
个人简历
严海丹,女,1986年11月出生,医学博士。2014年8月来福建医科大学任职,2018年6月毕业于哈尔滨医科大学生物医学工程专业获得医学博士学位。主要从事肿瘤生物信息学研究,研究方向为癌症预警、诊断、预后和耐药标志物的识别及肿瘤个体化子通路算法开发。主持国家自然科学基金青年项目1项,福建省自然科学基金和福建省教育厅项目各1项。在BriefingsinBioinformatics、JournalofTranslationalMedicine、NucleicAcidsResearch和BMCgenomics等杂志上发表论文10余篇,其中以第一作者发表论文8篇。研究领域
肿瘤生物信息学近期论文
1.YanH#(严海丹),LiM#,CaoL,ChenH,LaiH,GuanQ,ChenH,ZhouW,ZhengB,GuoZ,ZhengC.Arobustqualitativetranscriptionalsignatureforthecorrectpathologicaldiagnosisofgastriccancer.JTranslMed.2019Feb28;17(1):63.2.GuanQ#,ZengQ#,YanH#(严海丹),XieJ,ChengJ,AoL,HeJ,ZhaoW,ChenK,GuoY,GuanG,GuoZ.Aqualitativetranscriptionalsignaturefortheearlydiagnosisofcolorectalcancer.CancerSci.2019Jul23.3.YanH#(严海丹),CaiH#,GuanQ,HeJ,ZhangJ,GuoY,HuangH,LiX,LiY,GuY,QiL,GuoZ.IndividualizedanalysisofdifferentiallyexpressedmiRNAswithapplicationtotheidentificationofmiRNAsderegulatedcommonlyinlungcancertissues.BriefBioinform.2018Sep28;19(5):793-802.4.YanH#(严海丹),GuanQ#,HeJ,LinY,ZhangJ,LiH,LiuH,GuY,GuoZ,HeF.IndividualizedanalysisrevealsCpGsiteswithmethylationaberrationsinalmostalllungadenocarcinomatissues.JTranslMed.2017Feb8;15(1):26.5.YanH#(严海丹),HeJ#,GuanQ,CaiH,ZhangL,ZhengW,QiL,ZhangS,LiuH,LiH,ZhaoW,YangS,GuoZ.IdentifyingCpGsiteswithdifferentdifferentialmethylationfrequenciesincolorectalcancertissuesbasedonindividualizeddifferentialmethylationanalysis.Oncotarget.2017Jul18;8(29):47356-47364.6.GuanQ#,YanH#(严海丹),ChenY#,ZhengB,CaiH,HeJ,SongK,GuoY,AoL,LiuH,ZhaoW,WangX,GuoZ.Quantitativeorqualitativetranscriptionaldiagnosticsignatures?Acasestudyforcolorectalcancer.BMCGenomics.2018Jan29;19(1):99. 相关热点