个人简历

1987年毕业于上海医科大学公共卫生学系；1990年在上海医科大学神经生物学教研室获硕士学位。1990年至今，在上海医科大学神经生物学系，复旦大学医学神经生物学国家重点实验和脑科学研究院工作，历任助教、副教授和研究员。期间在2002年获复旦大学博士学位

研究领域

应激与脑老化促进与AD相关tau病理改变，以及Fyn抑制剂抗应激诱导tau蛋白磷酸化和聚集的机制；
细胞表面蛋白DR6和ATP合酶介导Aβ神经毒性作用的机制；
小分子化合物抗老年痴呆的研究

近期论文

Shan Y, Wang DD, Xu YX, Wang C, Cao L, Liu YS, Zhu CQ*(2016). Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid. J Alzheimers Dis. 49(3):829-844
Xu Y, Wang D, Luo Y, Li W, Shan Y, Tan X, Zhu CQ*(2015). Beta amyloid-induced upregulation of death receptor 6 accelerates the toxic effect of N-terminal fragment of amyloid precursor protein. Neurobiol Aging. 36(1):157-168
Xu Y, Zhang P, Wang C, Shan Y, Wang D, Qian F, Sun M, Zhu CQ*(2013). Effect of ginsenoside Rg3 on tyrosine hydroxylase and related mechanisms in the forced swimming-induced fatigue rats. J Ethnopharmacol. 150(1):138-147
Wang HQ, Xu YX, Zhu CQ*(2012). Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity. Neurotox Res. 21(4):368-378
Yan J, Sun XB, Wang HQ, Zhao H, Zhao XY, Xu YX, Guo JC, Zhu CQ*(2010).Chronic restraint stress alters the expression and distribution of phosphorylated tau and MAP2 in cortex and hippocampus of rat brain. Brain Res. 1347:132-141