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叶定伟
2023-05-10 09:45
  • 叶定伟
  • 叶定伟 - 副教授 硕导-复旦大学-生物医学研究院-个人资料

近期热点

资料介绍

个人简历


工作经历
1986.7―2002.5,第二军医大学附属长海医院泌尿外科(历任住院医师、主治医师、副主任医师、副教授、硕士研究生导师)
1996.9―1998.12,美国MDAndersonCancerCenter(访问学者、博士后)
2002.5―至今,复旦大学附属肿瘤医院(历任泌尿外科科主任、主任医师、教授、博士生导师)
2007.10―至今,复旦大学附属肿瘤医院副院长
教育经历
1981-09至1986-07,第二军医大学军医系,大学生
1990-09至1993-07,第二军医大学外科学系泌尿外科专业,硕士生
1997-09至2000-07,第二军医大学外科学系泌尿外科专业,博士生
所获人才项目
国家卫计委有突出贡献中青年专家,国家卫计委,2015
国务院特殊津贴,国务院,2013
上海领军人才,中共上海市委组织部,2011
上海医学领军人才,上海市卫生局,2011
恩德思医学科学技术奖杰出成就奖,恩德思医学科学技术奖评奖委员会,2011
复旦大学优秀人才院长奖金奖,复旦大学上海医学院,2010
上海市优秀学科带头人A类计划,上海市科委,2009
吴阶平泌尿外科医学奖,吴阶平泌尿外科医学基金会,1996
所获奖项
中国抗癌协会科技奖二等奖(第一完成人),中国抗癌协会,2016
上海市优秀发明选拔赛优秀发明金奖,上海市总工会,2016
国家科技进步一等奖(第三完成人),国务院,2012
上海市科技进步奖一等奖(第一完成人),上海市,2012
教育部科技进步奖二等奖(第一完成人),教育部,2012
上海市医学会科技奖一等奖(第一完成人),上海市医学会,2012
上海市科技进步一等奖(第一完成人),上海市,2010
中国抗癌协会科技奖二等奖(第一完成人),中国抗癌协会,2010
中华医学科技进步奖二等奖(第一完成人),中华医学会,2010
高等学校科技进步奖一等奖(第一完成人),教育部,2010
上海医学科技奖二等奖(第一完成人),上海市医学会,2010

近期论文


Ye,D.,Mendelsohn,J.,andFan,Z.(1999)Androgenandepidermalgrowthfactordown-regulatecyclin-dependentkinaseinhibitorp27Kip1andcostimulateproliferationofMDAPCa2aandMDAPCa2bprostatecancercells.Clinicalcancerresearch:anofficialjournaloftheAmericanAssociationforCancerResearch5,2171-2177
Ye,D.,Mendelsohn,J.,andFan,Z.(1999)Augmentationofahumanizedanti-HER2mAb4D5inducedgrowthinhibitionbyahuman-mousechimericanti-EGFreceptormAbC225.Oncogene18,731-738
Dai,B.,Ye,D.W.,Kong,Y.Y.,Yao,X.D.,Zhang,H.L.,andShen,Y.J.(2006)PredictingregionallymphnodemetastasisinChinesepatientswithpenilesquamouscellcarcinoma:theroleofhistopathologicalclassification,tumorstageanddepthofinvasion.TheJournalofurology176,1431-1435;discussion1435
Zhu,Y.,Zhou,X.Y.,Yao,X.D.,Dai,B.,andYe,D.W.(2007)Theprognosticsignificanceofp53,Ki-67,epithelialcadherinandmatrixmetalloproteinase-9inpenilesquamouscellcarcinomatreatedwithsurgery.BJUinternational100,204-208
Cao,D.L.,Ye,D.W.,Zhang,H.L.,Zhu,Y.,Wang,Y.X.,andYao,X.D.(2011)Amultiplexmodelofcombininggene-based,protein-based,andmetabolite-basedwithpositiveandnegativemarkersinurinefortheearlydiagnosisofprostatecancer.TheProstate71,700-710
Xu,J.,Mo,Z.,Ye,D.,Wang,M.,Liu,F.,Jin,G.,Xu,C.,Wang,X.,Shao,Q.,Chen,Z.,Tao,Z.,Qi,J.,Zhou,F.,Wang,Z.,Fu,Y.,He,D.,Wei,Q.,Guo,J.,Wu,D.,Gao,X.,Yuan,J.,Wang,G.,Xu,Y.,Wang,G.,Yao,H.,Dong,P.,Jiao,Y.,Shen,M.,Yang,J.,Ou-Yang,J.,Jiang,H.,Zhu,Y.,Ren,S.,Zhang,Z.,Yin,C.,Gao,X.,Dai,B.,Hu,Z.,Yang,Y.,Wu,Q.,Chen,H.,Peng,P.,Zheng,Y.,Zheng,X.,Xiang,Y.,Long,J.,Gong,J.,Na,R.,Lin,X.,Yu,H.,Wang,Z.,Tao,S.,Feng,J.,Sun,J.,Liu,W.,Hsing,A.,Rao,J.,Ding,Q.,Wiklund,F.,Gronberg,H.,Shu,X.O.,Zheng,W.,Shen,H.,Jin,L.,Shi,R.,Lu,D.,Zhang,X.,Sun,J.,Zheng,S.L.,andSun,Y.(2012)Genome-wideassociationstudyinChinesemenidentifiestwonewprostatecancerrisklociat9q31.2and19q13.4.Naturegenetics44,1231-1235
Ye,L.,Li,S.,Ye,D.,Yang,D.,Yue,F.,Guo,Y.,Chen,X.,Chen,F.,Zhang,J.,andSong,X.(2013)LivinexpressionmayberegulatedbymiR-198inhumanprostatecancercelllines.Europeanjournalofcancer(Oxford,England:1990)49,734-740
Zhu,Y.,Zhou,X.Y.,Yao,X.D.,Zhang,S.L.,Dai,B.,Zhang,H.L.,Shen,Y.J.,andYe,D.W.(2013)PrognosticvalueofcarbonicanhydraseIXexpressioninpenilesquamouscellcarcinoma:apilotstudy.Urologiconcology31,706-711
Zhu,Y.,andYe,D.W.(2014)Prostatecancer:alkalinephosphatasevelocityinnonmetastaticCRPC.Naturereviews.Urology11,666-667
Gu,W.,Zhang,G.,Sun,L.,Ma,Q.,Cheng,Y.,Zhang,H.,Shi,G.,Zhu,Y.,andYe,D.(2015)Nutritionalscreeningisstronglyassociatedwithoverallsurvivalinpatientstreatedwithtargetedagentsformetastaticrenalcellcarcinoma.Journalofcachexia,sarcopeniaandmuscle6,222-230
Li,F.,He,X.,Ye,D.,Lin,Y.,Yu,H.,Yao,C.,Huang,L.,Zhang,J.,Wang,F.,Xu,S.,Wu,X.,Liu,L.,Yang,C.,Shi,J.,He,X.,Liu,J.,Qu,Y.,Guo,F.,Zhao,J.,Xu,W.,andZhao,S.(2015)NADP(+)-IDHMutationsPromoteHypersuccinylationthatImpairsMitochondriaRespirationandInducesApoptosisResistance.Molecularcell60,661-675
Li,Q.,Gu,C.,Zhu,Y.,Wang,M.,Yang,Y.,Wang,J.,Jin,L.,Zhu,M.L.,Shi,T.Y.,He,J.,Ye,D.,andWei,Q.(2015)TwonovelPRKCIpolymorphismsandprostatecancerriskinanEasternChineseHanpopulation.Molecularcarcinogenesis54,632-641
Zhu,Y.,Dai,B.,Zhang,H.,Shi,G.,Shen,Y.,andYe,D.(2016)Longnon-codingRNALOC572558inhibitsbladdercancercellproliferationandtumorgrowthbyregulatingtheAKT-MDM2-p53signalingaxis.Cancerletters380,369-374
Wan,F.,Zhu,Y.,Han,C.,Xu,Q.,Wu,J.,Dai,B.,Zhang,H.,Shi,G.,Gu,W.,andYe,D.(2017)Identificationandvalidationofaneight-geneexpressionsignatureforpredictinghighFuhrmangraderenalcellcarcinoma.Internationaljournalofcancer140,1199-1208
Fu,H.,Zhu,Y.,Wang,Y.,Liu,Z.,Zhang,J.,Wang,Z.,Xie,H.,Dai,B.,Xu,J.,andYe,D.(2017)TumorInfiltratingMastCells(TIMs)ConfersaMarkedSurvivalAdvantageinNonmetastaticClear-CellRenalCellCarcinoma.Annalsofsurgicaloncology24,1435-1442
Tang,B.,Han,C.T.,Zhang,G.M.,Zhang,C.Z.,Yang,W.Y.,Shen,Y.,Vidal,A.C.,Freedland,S.J.,Zhu,Y.,andYe,D.W.(2017)Waist-hipRatio(WHR),aBetterPredictorforProstateCancerthanBodyMassIndex(BMI):ResultsfromaChineseHospital-basedBiopsyCohort.Scientificreports7,43551
Wang,Y.,Dai,B.,andYe,D.W.(2017)Serumtestosteronelevelpredictstheeffectivetimeofandrogendeprivationtherapyinmetastaticprostatecancerpatients.Asianjournalofandrology19,178-183
Qu,Y.,Gu,C.,Wang,H.,Chang,K.,Yang,X.,Zhou,X.,Dai,B.,Zhu,Y.,Shi,G.,Zhang,H.,andYe,D.(2016)DiagnosisofadultsXp11.2translocationrenalcellcarcinomabyimmunohistochemistryandFISHassays:clinicopathologicaldatafromethnicChinesepopulation.Scientificreports6,21677
Zhu,Y.P.,Wan,F.N.,Shen,Y.J.,Wang,H.K.,Zhang,G.M.,andYe,D.W.(2015)ReactivestromacomponentCOL6A1isupregulatedincastration-resistantprostatecancerandpromotestumorgrowth.Oncotarget6,14488-14496

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