个人简历

复旦大学生命科学学院教授、博士生导师(2011至今)，医至今学神经生物学国家重点实验室研究员(2013)。兰州大学物理系学士(1995)，南京大学凝聚态物理学博士(2001)，美国卡耐基梅隆大学计算神经科学博士后(2001-2004)，耶鲁大学计算神经科学研究科学家(2010-2012),耶鲁大学定量核磁共振成像中心高级访问学者(2017), 上海高校教授‘东方学者’（2013）和跟踪计划（2017）。Frontiers in Computational Neuroscience和Cognitive Neurodynamics等杂志编委。应用物理学理论和数学模型，结合实验方法进行跨学科研究大脑脑皮层神经电活动规律和信息处理机制、脑认知计算方式和能量代谢机制。在Nature, PNAS, Neuron, Physical Review Letters, Journal of Neuroscience, PLoS Compuational Biology，EBioMedicine等SCI学术期刊发表论文50余篇

研究领域

1 计算神经科学
2 神经信息处理机制
3 神经活动能量效率
4 学习和记忆认知功能的脑复杂网络研究
5 癫痫等脑疾病的神经电生理实验研究"计算神经科学和神经电生理学
专长：在物理学、生物物理、神经生物学实验和计算神经科学等多学科接受了系统学术训练，掌握了应用跨学科技术方法对神经科学的前沿课题进行综合交叉研究的技术和方法。目前主要应用数学模型、非线性动力学、统计和信息理论，并结合神经电生理实验等多学科技术手段，综合交叉研究脑皮层神经信号的能量效率和信息编码机制、神经计算机理、脑电信号活动规律、神经活动紊乱的动力学变化规律等关键科学问题。目前，课题组已经结合复旦大学数学学院计算系统生物学中心的计算资源、耶鲁大学神经生物学系的神经生物学实验数据、复旦大学脑研究院的神经疾病实验研究的实验数据，在神经元水平上重点研究脑电信号高效节能的生物物理机制，在皮层网络水平上着重研究脑疾病发生发展过程中的能量紊乱特征、信号活动规律和病理状态的神经信息处理缺陷机制，推动对如癫痫、脑瘤、缺血缺氧等脑疾病的多学科交叉研究，揭示脑疾病的能量紊乱机制。目前已经在国际一流学术期刊发表学术论文30多篇，研究成果分别发表在国际顶级学术刊物如《Nature》、《PhysicalReviewLetters》、《JournalofNeuroscience》、《Neuron》、《PNAS》和《PLoSComputationalBiology》等上面。并被NatureReviewNeuroscience

近期论文

Du MM, *Yu YG and *Wu Y, (2018) Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure, PLoS Comp. Biol. 14(3): e1005877
Zhang W, Fan BQ, Agarwal D, Li T and *Yu YG (2018). Axonal sodium and potassium conductance density determines spiking dynamical properties of regular- and fast-spiking neurons, Nonlinear Dynamics, https://doi.org/10.1007/s11071-018-4613-3
Yu, L., Shen, Z., Wang, C., & *Yu YG (2018). Efficient coding and energy efficiency are promoted by balanced excitatory and inhibitory synaptic currents in neuronal network. Frontiers in cellular neuroscience, 12, 123.
Wang YY, Wang PX and *Yu YG, (2018) Decoding English alphabet letters using EEG phase information, Frontiers in Neuroscience. 12:62. doi: 10.3389/fnins.2018.00062.
*Yu YG, Herman P, Rothman DL, Agarwal D and Hyder F, (2017) Evaluating the gray and white matter energy budgets of human brain function, Journal of Cerebral Blood Flow & Metabolism, 0271678X17708691, DOI: 10.1177/0271678X17708691
Ju H, Hines ML, *Yu YG, (2016) Cable energy function of cortical axons, Sci Rep. 6:29686.
Pan XL. et al., ... *Yu YG and *Zhong, C.J. (*Co-PI) (2016) Measurement of Blood Thiamine Metabolites for Alzheimer’s disease Diagnosis, EBioMedicine, 26(3):155-162.
*Yu, Y.G., Migliore, M, Hines ML, and Shepherd GM， (2014) Sparse coding and lateral inhibition arising from balanced and unbalanced dendrodendritic excitation and inhibition, Journal of Neuroscience, 34: 13701-13713.
Yu YG, McTavish TS, Valenti C, Hines ML, Shepherd GM and Migliore M. (2013) Sparse distributed representation of odors in a large-scale olfactory bulb circuit. PLoS Comp. Biol., 2013 9(3): e1003014.
Yu YG, Hill A. and McCormick DA. (2012). Warm body temperature facilitates energy efficient cortical action potentials. PLoS Comp. Biol., 8(4) e1002456.
Yu YG, Maureira C and McCormick DA (2010) P/Q and N channels control baseline and spike-triggered calcium levels in neocortical axons and synaptic boutons, J Neurosci, 30: 118580-11869.
Haider B, Krause MR, Duque A, Yu YG, Touryan J, Mazer JA, McCormick DA (2010) Synaptic and network mechanisms of sparse and reliable visual cortical activity during non-classical receptive field stimulation. Neuron, 65: 107-121.
Yu YG, Shu Y, Duque A, Haider B and McCormick DA (2008) Cortical Action Potential Back-propagation Explains Spike Threshold Variability and Rapid-Onset Kinetics. J Neurosci, 28: 7260-7272.
McCormick DA, Shu Y and Yu YG (2007) Hodgkin and Huxley model—still standing? Nature. 445: E1-E2.
Shu Y, Hasenstaub A, Duque A, Yu YG and McCormick DA (2006) Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential. Nature 441(7094):761-5.
*Yu YG, Richard RD and Lee TS (2005) Preference of sensory neural coding for 1/f signals. Phys Rev Lett, 94, 1081031-4.
*Yu YG and Lee TS (2003) Dynamical mechanisms underlying contrast gain control in single neurons. Phys Rev E 68, 0119011-0119017.
*Yu YG, Wang, W., Wang, J.F., and Liu, F. Resonance-enhanced signal detection and transduction in Hodgkin-Huxley neuronal systems. Phys Rev E, 63, 0219071-02190712, (2001).