个人简历

工作经历
青年研究员，复旦大学，生物医学研究院/儿科医院（2018.9-今）
博士后，美国圣裘德儿童研究医院（2014.6-2018.8）
高级研究员/生信组长，上海药明康德基因组学中心（现药明明码）（2011.9-2014.5）
教育经历
遗传学博士，中国科学院上海生命科学研究院/中国科学院大学(2004.9-2011.5)
理学学士，浙江大学，生命科学院（2000.9-2004.7）

近期论文

1.QianM#,XuH#,Perez-AndreuV,RobertsKG,ZhangH,YangW,ZhangS,ZhaoX,SmithC,DevidasM,Gastier-FosterJM,RaetzE,LarsenE,BurchardEG,WinickN,BowmanWP,MartinPL,BorowitzM,WoodB,Antillon-KlussmannF,PuiCH,MullighanCG,EvansWE,HungerSP,RellingMV,LohML,andYangJJ.NovelsusceptibilityvariantsattheERGlocusforchildhoodacutelymphoblasticleukemiainHispanics.Blood.2018.(Accepted).
2.ChurchmanML#,QianM#,TeKronnieG#,ZhangR,YangW,ZhangH,LanaT,TedrickP,BaskinR,VerbistK,PetersJL,DevidasM,LarsenE,MooreIM,GuZ,QuC,YoshiharaH,PorterSN,Pruett-MillerSM,WuG,RaetzE,MartinPL,BowmanWP,WinickN,MardisE,FultonR,StanullaM,EvansWE,RellingMV,PuiCH,HungerSP,LohML,HandgretingerR,NicholsKE,YangJJ*,MullighanCG*.GermlineGeneticIKZF1VariationandPredispositiontoChildhoodAcuteLymphoblasticLeukemia.CancerCell.2018May14;33(5):937-948.e8.doi:10.1016/j.ccell.2018.03.021.Epub2018Apr19.PMID:29681510.
3.QianM,CaoX,DevidasM,YangW,ChengC,DaiY,CarrollA,HeeremaNA,ZhangH,MoriyamaT,Gastier-FosterJM,XuH,RaetzE,LarsenE,WinickN,BowmanWP,MartinPL,MardisER,FultonR,ZambettiG,BorowitzM,WoodB,NicholsKE,CarrollWL,PuiCH,MullighanCG,EvansWE,HungerSP,RellingMV,LohML,YangJJ.TP53GermlineVariationsInfluencethePredispositionandPrognosisofB-CellAcuteLymphoblasticLeukemiainChildren.JClinOncol.2018Jan4;JCO2017755215.PMID:29300620.
4.LiL#,QianM#,ChenIH,FinkelsteinD,Onar-ThomasA,JohnsonM,CalabreseC,BahramiA,López-TerradaDH,YangJJ,TaoWA,ZhuL.AcquisitionofCholangiocarcinomaTraitsduringAdvancedHepatocellularCarcinomaDevelopmentinMice.AmJPathol.2017Dec14;PMID:29248454.
5.HuS#,QianM#,ZhangH#,GuoY#,YangJ,ZhaoX,HeH,LuJ,PanJ,ChangM,DuG,LinTN,KhamSK,QuahTC,AriffinH,TanAM,ChengY,LiC,YeohAE,PuiCH,SkanderupAJ,YangJJ.Whole-genomenoncodingsequenceanalysisinT-cellacutelymphoblasticleukemiaidentifiesoncogeneenhancermutations.Blood.2017Jun15;129(24):3264-3268.PMID:28408461.
6.QianM#,ZhangH#,KhamSK,LiuS,JiangC,ZhaoX,LuY,GoodingsC,LinTN,ZhangR,MoriyamaT,YinZ,LiZ,QuahTC,AriffinH,TanAM,ShenS,BhojwaniD,HuS,ChenS,ZhengH,PuiCH,YeohAE*,YangJJ*.Whole-transcriptomesequencingidentifiesadistinctsubtypeofacutelymphoblasticleukemiawithpredominantgenomicabnormalitiesofEP300andCREBBP.GenomeRes.2017Feb;27(2):185-195.PMID:27903646.
7.ZhangY#,GaoY#,ZhangH#,ZhangJ,HeF,HnízdaA,QianM,LiuX,GochoY,PuiCH,ChengT,WangQ,YangJJ*,ZhuX*,LiuX*.PDGFRBmutationandtyrosinekinaseinhibitorresistanceinPh-likeacutelymphoblasticleukemia.Blood,2018May17;131(20):2256-2261.PMID:29434033.
8.MoriyamaT#,MetzgerML#,WuG#,NishiiR,QianM,DevidasM,YangW,ChengC,CaoX,QuinnE,RaimondiS,Gastier-FosterJM,RaetzE,LarsenE,MartinPL,BowmanWP,WinickN,KomadaY,WangS,EdmonsonM,XuH,MardisE,FultonR,PuiCH,MullighanC,EvansWE,ZhangJ,HungerSP,RellingMV,NicholsKE,LohML,YangJJ.GermlinegeneticvariationinETV6andriskofchildhoodacutelymphoblasticleukaemia:asystematicgeneticstudy.LancetOncol.2015Dec;16(16):1659-66.doi:10.1016/S1470-2045(15)00369-1.PMID:26522332.
9.XuH#,ZhangH#,YangW,YadavR,MorrisonAC,QianM,DevidasM,LiuY,Perez-AndreuV,ZhaoX,Gastier-FosterJM,LupoPJ,NealeG,RaetzE,LarsenE,BowmanWP,CarrollWL,WinickN,WilliamsR,HansenT,HolmJC,MardisE,FultonR,PuiCH,ZhangJ,MullighanCG,EvansWE,HungerSP,GuptaR,SchmiegelowK,LohML,RellingMV,YangJJ.InheritedcodingvariantsattheCDKN2Alocusinfluencesusceptibilitytoacutelymphoblasticleukaemiainchildren.NatCommun.2015Jun24;6:7553.doi:10.1038/ncomms8553.PMID:26104880.
10.FangDD#,ZhangB#,GuQ,LiraM,XuQ,SunH,QianM,ShengW,OzeckM,WangZ,ZhangC,ChenX,ChenKX,LiJ,ChenSH,ChristensenJ,MaoM,ChanCC.HIP1-ALK,anovelALKfusionvariantthatrespondstocrizotinib.JThoracOncol.2014Mar;9(3):285-94.doi:10.1097/JTO.0000000000000087.PMID:24496003.
11.QianM,JinW,ZhuX,JiaX,YangX,DuY,WangK,ZhangJ.Structurallydifferentiatedcis-elementsthatinteractwithPU.1arefunctionallydistinguishableinacutepromyelocyticleukemia.JHematolOncol.2013Apr2;6:25.doi:10.1186/1756-8722-6-25.PMID:23547873.
12.ZhuX#,ZhangH#,QianM,ZhaoX,YangW,WangP,ZhangJ,WangK.ThesignificanceoflowPU.1expressioninpatientswithacutepromyelocyticleukemia.JHematolOncol.2012May8;5:22.doi:10.1186/1756-8722-5-22.PMID:22569057.
13.WangK#,WangP#,ShiJ#,ZhuX#,HeM,JiaX,YangX,QiuF,JinW,QianM,FangH,MiJ,YangX,XiaoH,MindenM,DuY,ChenZ,ZhangJ.PML/RARalphatargetspromoterregionscontainingPU.1consensusandRAREhalfsitesinacutepromyelocyticleukemia.CancerCell.2010Feb17;17(2):186-97.doi:10.1016/j.ccr.2009.12.045.PMID:20159610.