个人简历

工作经历
研究员，复旦大学，生物医学研究院/附属肿瘤医院（2016.12-今）
教授，中国科学技术大学，生命科学学院（2012.11-2016.11）
研究助理教授，美国密西根大学（2010.10-2012.10）
助理研究员，美国密西根大学（2006.10-2010.09）
博士后，美国密西根大学（2003.12-2006.09）
教育经历
博士，美国俄亥俄州立大学，生物学系（1997-2003）
学士，中国科学技术大学，生物系（1992-1997）
所获人才项目
国家优秀青年科学基金，国家自然科学基金，2014
所获奖项
中美抗癌协会-美国国家癌症基金学术奖，中美抗癌协会，2014
SusanG.KomenScholarinTrainingAward，美国癌症协会，2010
MerckScholarinTrainingAward，美国癌症协会，2006

近期论文

Qin,Y.,Chen,W.,Liu,B.,Zhou,L.,Deng,L.,Niu,W.,Bao,D.,Cheng,C.,Li,D.,Liu,S.*,Niu,C.*.(2017)MiR-200cInhibitstheTumorProgressionofGliomaviaTargetingMoesin.Theranostics7(6):1663-1673.
Liu,Y.,Burness,M.L.,Martin-Trevino,R.,Guy,J.,Bai,S.,Harouaka,R.,Brooks,M.D.,Shang,L.,Fox,A.,Luther,T.K.,Davis,A.,Baker,T.L.,Colacino,J.,Clouthier,S.G.,Shao,Z.M.,Wicha,M.S.,andLiu,S.*(2017)RAD51MediatesResistanceofCancerStemCellstoPARPInhibitioninTriple-NegativeBreastCancer.Clinicalcancerresearch:anofficialjournaloftheAmericanAssociationforCancerResearch23,514-522
Zhao,Z.,Li,S.,Song,E.,andLiu,S.*(2016)TherolesofncRNAsandhistone-modifiersinregulatingbreastcancerstemcells.Protein&cell7,89-99
Liu,R.,Shi,P.,Nie,Z.,Liang,H.,Zhou,Z.,Chen,W.,Chen,H.,Dong,C.,Yang,R.,Liu,S.,andChen,C.(2016)MifepristoneSuppressesBasalTriple-NegativeBreastCancerStemCellsbyDown-regulatingKLF5Expression.Theranostics6,533-544
Ke,J.,Zhao,Z.,Hong,S.H.,Bai,S.,He,Z.,Malik,F.,Xu,J.,Zhou,L.,Chen,W.,Martin-Trevino,R.,Wu,X.,Lan,P.,Yi,Y.,Ginestier,C.,Ibarra,I.,Shang,L.,McDermott,S.,Luther,T.,Clouthier,S.G.,Wicha,M.S.,andLiu,S.*(2015)RoleofmicroRNA221inregulatingnormalmammaryepithelialhierarchyandbreastcancerstem-likecells.Oncotarget6,3709-3721
Sun,S.,Liu,S.,Duan,S.Z.,Zhang,L.,Zhou,H.,Hu,Y.,Zhou,X.,Shi,C.,Zhou,R.,andZhang,Z.(2014)Targetingthec-Met/FZD8signalingaxiseliminatespatient-derivedcancerstem-likecellsinheadandnecksquamouscarcinomas.CancerRes74,7546-7559
Lombardi,S.,Honeth,G.,Ginestier,C.,Shinomiya,I.,Marlow,R.,Buchupalli,B.,Gazinska,P.,Brown,J.,Catchpole,S.,Liu,S.,Barkan,A.,Wicha,M.,Purushotham,A.,Burchell,J.,Pinder,S.,andDontu,G.(2014)GrowthHormoneIsSecretedbyNormalBreastEpitheliumuponProgesteroneStimulationandIncreasesProliferationofStem/ProgenitorCells.StemCellReports2,780-793
Liu,S.*,Cong,Y.,Wang,D.,Sun,Y.,Deng,L.,Liu,Y.,Martin-Trevino,R.,Shang,L.,McDermott,S.P.,Landis,M.D.,Hong,S.,Adams,A.,D'Angelo,R.,Ginestier,C.,Charafe-Jauffret,E.,Clouthier,S.G.,Birnbaum,D.,Wong,S.T.,Zhan,M.,Chang,J.C.,andWicha,M.S.(2014)BreastCancerStemCellsTransitionbetweenEpithelialandMesenchymalStatesReflectiveoftheirNormalCounterparts.StemCellReports2,78-91
Deng,L.,Shang,L.,Bai,S.,Chen,J.,He,X.,Martin-Trevino,R.,Chen,S.,Li,X.-Y.,Meng,X.,Yu,B.,Wang,X.,Liu,Y.,McDermott,S.P.,Ariazi,A.E.,Ginestier,C.,Ibarra,I.,Ke,J.,Luther,T.,Clouthier,S.G.,Xu,L.,Shan,G.,Song,E.,Yao,H.,Hannon,G.J.,Weiss,S.J.,Wicha,M.S.,andLiu,S.*(2014)MicroRNA100InhibitsSelf-RenewalofBreastCancerStem-likeCellsandBreastTumorDevelopment.Cancerresearch74,6648-6660
Luo,M.,Zhao,X.,Chen,S.,Liu,S.,Wicha,M.S.,andGuan,J.-L.(2013)DistinctFAKActivitiesDetermineProgenitorandMammaryStemCellCharacteristics.CancerResearch73,5591-5602
Liu,S.*,Patel,S.H.,Ginestier,C.,Ibarra,I.,Martin-Trevino,R.,Bai,S.,McDermott,S.P.,Shang,L.,Ke,J.,Ou,S.J.,Heath,A.,Zhang,K.J.,Korkaya,H.,Clouthier,S.G.,Charafe-Jauffret,E.,Birnbaum,D.,Hannon,G.J.,andWicha,M.S.(2012)MicroRNA93RegulatesProliferationandDifferentiationofNormalandMalignantBreastStemCells.PlosGenetics8
Liu,S.,Clouthier,S.G.,andWicha,M.S.(2012)RoleofmicroRNAsintheRegulationofBreastCancerStemCells.JournalofMammaryGlandBiologyandNeoplasia17,15-21
Korkaya,H.,Kim,G.-i.,Davis,A.,Malik,F.,Henry,N.L.,Ithimakin,S.,Quraishi,A.A.,Tawakkol,N.,D'Angelo,R.,Paulson,A.K.,Chung,S.,Luther,T.,Paholak,H.J.,Liu,S.,Hassan,K.A.,Zen,Q.,Clouthier,S.G.,andWicha,M.S.(2012)ActivationofanIL6InflammatoryLoopMediatesTrastuzumabResistanceinHER2+BreastCancerbyExpandingtheCancerStemCellPopulation.MolecularCell47,570-584
Liu,S.*,Ginestier,C.,Ou,S.J.,Clouthier,S.G.,Patel,S.H.,Monville,F.,Korkaya,H.,Heath,A.,Dutcher,J.,Kleer,C.G.,Jung,Y.,Dontu,G.,Taichman,R.,andWicha,M.S.(2011)BreastCancerStemCellsAreRegulatedbyMesenchymalStemCellsthroughCytokineNetworks.CancerResearch71,614-624
Korkaya,H.,Liu,S.,andWicha,M.S.(2011)Breastcancerstemcells,cytokinenetworks,andthetumormicroenvironment.JournalofClinicalInvestigation121,3804-3809
Liu,S.,andWicha,M.S.(2010)TargetingBreastCancerStemCells.JournalofClinicalOncology28,4006-4012
Ginestier,C.,Liu,S.,Diebel,M.E.,Korkaya,H.,Luo,M.,Brown,M.,Wicinski,J.,Cabaud,O.,Charafe-Jauffret,E.,Birnbaum,D.,Guan,J.-L.,Dontu,G.,andWicha,M.S.(2010)CXCR1blockadeselectivelytargetshumanbreastcancerstemcellsinvitroandinxenografts.JournalofClinicalInvestigation120,485-497
Ginestier,C.,Liu,S.,andWicha,M.S.(2009)GettingtotheRootofBRCA1-DeficientBreastCancer.CellStemCell5,229-230
Liu,S.,Ginestier,C.,Charafe-Jauffret,E.,Foco,H.,Kleer,C.G.,Merajver,S.D.,Dontu,G.,andWicha,M.S.(2008)BRCA1regulateshumanmammarystem/progenitorcellfate.ProceedingsoftheNationalAcademyofSciencesoftheUnitedStatesofAmerica105,1680-1685
Ginestier,C.,Hur,M.H.,Charafe-Jauffret,E.,Monville,F.,Dutcher,J.,Brown,M.,Jacquemier,J.,Viens,P.,Kleer,C.G.,Liu,S.,Schott,A.,Hayes,D.,Birnbaum,D.,Wicha,M.S.,andDontu,G.(2007)ALDH1isamarkerofnormalandmalignanthumanmammarystemcellsandapredictorofpoorclinicaloutcome.CellStemCell1,555-567
Liu,S.,Dontu,G.,Mantle,I.,Patel,S.,Ahn,N.,Jackson,K.,Suri,P.,andWicha,M.(2006)HedgehogsignalingandBmi-1regulateself-renewalofnormalandmalignanthumanmammarystemcells.CancerResearch66,6063-6071