个人简历

2012.12月-至今：复旦大学上海医学院免疫学系 教授，博士生导师，课题组长
2009.11-2012.11：复旦大学上海医学院免疫学系 副研究员，博士生导师，课题组长
2004.9---2009.10：哈佛大学波士顿儿童医院免疫学系 博士后
1999.9 ---2004.7：中国协和医科大学 医学博士
1994.9 ---1999.7：华西医科大学临床医学本科

研究领域

粘膜免疫和肿瘤炎症的调节机制"在研项目
2019.5.1-2021.4.30上海市“优秀学科带头人”（19XD1400200）负责人
肿瘤相关成纤维细胞调控髓样细胞促肿瘤干性能力的机制研究
2018.1-2021.12NSFC面上项目（81771679）负责人
LTB4-BLT1轴对IL-33和2型固有淋巴样细胞（ILC2）的作用及其介导过敏性气道炎症的机制研究
2016.9-2020.12科技部重点专项（2016YFC1305100）子课题负责人
“1型糖尿病的遗传与免疫发病机制和相关防控技术研究”
2018.5.1-2021.4.30上海市“科技创新行动计划”（18140903300）负责人“联合条件敲除pDC的气道致敏诱发小鼠哮喘模型的建立以及pDC调节呼吸道病毒感染诱发哮喘的研究”
已结题项目
017.01-2019.12NSFC重大研究计划（91642112）负责人
“肠上皮STAT6活化导致肠道免疫紊乱和肠炎/癌发生发展的机制研究”
2015.1-2018.12NSFC优秀青年项目；免疫炎症调节
国家自然科学基金面上项目（81471555）负责人
“Chemerin抑制肝癌及调控肝癌炎症微环境的机制研究”
2015.1-2020.1科技部“973”项目（2015CB553400）研究骨干
“大气细颗粒物引发呼吸道损伤的病理生理学机制与干预研究”
2012.1-2015.12国家自然科学基金面上项目（81172797）负责人
“Chemerin对免疫炎症的影响及作用机制的研究”"

近期论文

Xiao L, Yang X, Lin Y, Li S, Jiang J, Qian S, Tang Q, He R*, Li X*. Large adipocytes function as antigen presenting cells to activate CD4+ T cells via up-regulating MHCII in obesity. Int J Obes 2015 Aug 7. [Epub ahead of print]. IF: 5.08
Lv J, Zou L, Zhao L, Yang W, Xiong Y, Li B, He R*. LTB4-BLT1 axis promotes OXA-induced contact dermatitis by directing skin homing of neutrophils and CD8+ T cells. Immunology 2015 May 9. [Epub ahead of print]. IF: 3.8
Wang L, Ray A, Jiang X, Wang JY, Basu S, Liu X, Qian T, He R, Dittel BN, Chu Y. T regulatory cells and B cells cooperate to form a regulatory loop that maintains gut homeostasis and suppresses dextran sulfate sodium-induced colitis. 2015 Mar 25. Mucosal Immunol [Epub ahead of print].
IF: 7.54
Liang M, Lv J, Zou L, Yang W, Xiong Y, Chen X, Guan M, He R*, Zou H*. A modified murine model of systemic sclerosis: bleomycin given by pump infusion induced skin and pulmonary inflammation and fibrosis. Lab Invest. 2015 Mar;95(3):342-50. IF:3.7
Li X, Xu J, Lv Z, Wang J, Sun S, Zhu W, Wang B, He R, Qu D. Inadequate activation of the HBsAg-specific Th cells by APCs leads to hyporesponsiveness to HBsAg vaccine in B10.S mice. Hum Vaccin Immunother. 2015 Jun 17:0. [Epub ahead of print]. IF: 2.4
Liu WR, Tian MX1, Yang LX, Lin YL, Jin L, Ding ZB, Shen YH, Peng YF, Gao DM, Zhou J, Qiu SJ, Dai Z, He R, Fan J, Shi YH. PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma. Oncotarget. 2015 Jan 20;6(2):846-61. IF:6.4
Zhao L, Yang W, Yang X, Lin Y, Lv J, Dou X, Luo Q, Dong J, Chen Z, Chu Y and He R*. Chemerin suppresses murine allergic asthma by inhibiting CCL2 production and subsequent airway recruitment of inflammatory dendritic cells. Allergy 2014 Jun;69(6):763-74. IF: 6
Lin Y, Yang X, Yue W, Xu X, Li B, Zou L and He R*. Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization. Cellular & Molecular Immunol 2014 Jul;11(4):355-66. IF: 4.1
Yin Q, Xu X, Lin Y, Lv J, Zhao L, and He R*. Ultraviolet B irradiation induces skin accumulation of plasmacytoid dendritic cells: A possible role for chemerin. Autoimmunity 2014 May;47(3):185-92. IF: 2.7
Wang L, Zhao L, Lv J, Yin Q, Liang X, Chu Y and He R*. BLT1-dependent alveolar recruitment of CD4+CD25+ Foxp3+ regulatory T cells is important for resolution of acute lung injury. Am J Respir Crit Care Med 2012, 186(10):989-98. IF: 13
Oyoshi MK, He R (Co-first author), Li Y, Mondal, S, Yoon J, Afshar R, Chen M ,Lee DM, Luo HR, Luster AD, Cho JS, Miller LS, Larson A, Murphy GF and Geha RS. LTB4 driven neutrophil recruitment to the skin is essential for allergic skin inflammation Immunity 2012, 37(4):747-58. IF: 21.6
Oyoshi MK, He R, Elkhal A, Kawamoto S, Lewis C, Kanaoka Y, Austen KF, and Geha RS. Eosinophil-derived LTC4 signals via CysLT2R to promote skin thickening and collagen deposition in a mouse model of allergic skin inflammation. Proc Natl Acad Sci U S A 2012;109(13):4992-7. IF: 9.7
He R, Oyoshi MK, Wang JY, Hodge MR, Jin H, and Geha RS. The prostaglandin D(2) receptor CRTH2 is important for allergic skin inflammation after epicutaneous antigen challenge. J Allergy Clin Immunol. 2010; 126(4):784-90. IF: 11.5
He R, Kim HY, Yoon J, Oyoshi MK, MacGinnitie A, Goya S , Bryce P, Freyschmidt EJ, McKenzie AJ, Umetsu DT, Oettgen HC and Geha RS. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol 2009; 124(4):761-770.e1. IF: 11.5
He R and Geha RS. Thymic Stromal Lymphopoietin. Ann N Y Acad Sci. 2010;1183:13-24. IF: 4.4
Oyoshi MK, Elkhal A, Kumar L, Scott J, Koduru S, He R, Leung DY, Howell MD, Oettgen HC, Murphy GF, and Geha RS. IL-17 promotes dissemination of vaccinia virus in a mouse model of eczema vaccinatum. Proc Natl Acad Sci U S A 2009;106(35):14954-9. IF: 9.7
Oyoshi MK, He R, Kumar L, Yoon J and Geha RS. Cellular and molecular mechanisms in Atopic dermatitis. Adv Immunol 2009;102:135-226. IF: 6
He R, Oyoshi MK, Garibyan L, Kumar L, Ziegler SF and Geha RS. TSLP acts on infiltrating effector T cells to drive allergic skin inflammation. Proc Natl Acad Sci U S A 2008; 105(33):11875-80.
IF: 9.7
He R, Oyoshi MK, Jin H, Geha RS. Epicutaneous antigen exposure induces a TH17 response that drives airway inflammation after inhalation challenge. Proc Natl Acad Sci USA 2007; 104(40): 15817-22. IF: 9.7
Jin H, He R ( Co-first author), Oyoshi MK, Geha RS. Animal models of atopic dermatitis. J Invest Dermatol; 2009; 129(1):31-40. IF: 7.2
Yalcindag A, He R*( Co-first author), Laouini D, Alenius H, Carroll M, Oettgen HC, Geha RS. The complement component C3 plays a critical role in both Th1 and Th2 responses to antigen. J Allergy Clin Immunol. 2006; 117(6):1455-61. IF: 11.5
Elkhal A, Pichavant M, He R, Scott J, Meyer E, Goya S, Geha RS, Umetsu DT. CD1d restricted natural killer T cells are not required for allergic skin inflammation. J Allergy Clin Immunol. 2006;118(6):1363-8. IF: 11.5
Xu ZS, Liu YJ, Lv LL, Han ZB, He R, Lu SH, Wang T, Xu B, Chen ZZ, Han ZC. Bone marrow stromal cells transduced with human hemangiopoietin gene support hematopoiesis in vitro. Haematologica. 2005;90(2):157-65. IF: 5.87
He R, Liu B, Yang C, Yang RC, Tobelem G, Han ZC. Inhibition of K562 leukemia angiogenesis and growth by expression of antisense vascular endothelial growth factor (VEGF) sequence. Cancer Gene Ther. 2003;10(12):879-86. IF: 2.55
中国免疫学会女科学家工作委员会委员
中国免疫学会科学普及教育工作委员会委员
中国细胞生物学会免疫细胞生物分会委员
中国病理生理学会免疫专业委员会委员
中国抗癌协会肿瘤微环境专业委员会委员
上海免疫学会第十二届理事会理事