个人简历

工作经历
特聘教授，复旦大学附属中山医院（2019.11-至今）
研究员（破格），复旦大学附属中山医院（2016.12-至今）
副主任医师，复旦大学附属中山医院（2015.12-至今）
主治医师，复旦大学附属中山医院（2009.7-2015.11）
住院医师，复旦大学附属中山医院（2008.7-2009.06）
教育经历
硕博连读复旦大学附属中山医院（2003.9-2008.7）
学士蚌埠医学院临床医学系（1998.9-2003.7）
所获人才项目
长江学者奖励计划“特聘教授”(2018)
国家优秀青年科学基金(2016)
长江学者奖励计划“青年学者”(2015)
万人计划“青年拔尖人才”(2015)
上海市优秀学科带头人(2017)
上海市优秀学术带头人(2019)
上海市“曙光计划”（2017）
上海市优秀青年医学人才(2013)
上海市“青年科技启明星计划”（2010）
所获奖项
教育部青年科学奖（2017）
教育部自然科学一等奖（2016）
上海市科技创新“市长奖”（2015）
树兰医学青年奖（2015）
吴孟超医学青年奖（2013）
上海市“银蛇奖”二等奖（2013）
卫生系统“全国青年岗位能手”（2012）
复旦大学“十大医务青年”（2011）
全国优秀博士学位论文（2010）
复旦大学“校长奖”（2008）

研究领域

肿瘤异质性和个体化治疗

近期论文

(1)GaoQ,ZhuH,DongL,ShiW,ChenR,SongZ,HuangC,LiJ,DongX,ZhouY,LiuQ,MaL,WangX,ZhouJ,LiuY,BojaE,RoblesAI,MaW,WangP,LiY,DingL,WenB,ZhangB,RodriguezH,GaoD,ZhouH,FanJ.IntegratedProteogenomicCharacterizationofHBV-RelatedHepatocellularCarcinoma.Cell.2019Oct3;179(2):561-577.e22.
(2)LiuLZ,ZhangZ,ZhengBH,ShiY,DuanM,MaLJ,WangZC,DongLQ,DongPP,ShiJY,ZhangS,DingZB,KeAW,CaoY,ZhangXM,XiR,ZhouJ,FanJ#,WangXY#,GaoQ#.CCL15RecruitsSuppressiveMonocytestoFacilitateImmuneEscapeandDiseaseProgressioninHepatocellularCarcinoma.Hepatology.2019Jan;69(1):143-159.
(3)DuanM,GoswamiS,ShiJY,WuLJ,WangXY,MaJQ,ZhangZ,ShiY,MaLJ,ZhangS,XiRB,CaoY,ZhouJ,FanJ#,ZhangXM#,GaoQ#.ActivatedandExhaustedMAITCellsFosterDiseaseProgressionandIndicatePoorOutcomeinHepatocellularCarcinoma.ClinCancerRes.2019Jun1;25(11):3304-3316.
(4)DongLQ,ShiY,MaLJ,YangLX,WangXY,ZhangS,WangZC,DuanM,ZhangZ,LiuLZ,ZhengBH,DingZB,KeAW,GaoDM,YuanK,ZhouJ,FanJ#,XiR#,GaoQ#.Spatialandtemporalclonalevolutionofintrahepaticcholangiocarcinoma.JHepatol.2018Jul;69(1):89-98.
(5)MaLJ,FengFL,DongLQ,ZhangZ,DuanM,LiuLZ,ShiJY,YangLX,WangZC,ZhangS,DingZB,KeAW,CaoY,ZhangXM,ZhouJ,FanJ,WangXY#,GaoQ#.ClinicalsignificanceofPD-1/PD-Lsgeneamplificationandoverexpressioninpatientswithhepatocellularcarcinoma.Theranostics.2018Nov10;8(20):5690-5702.
(6)LiZ,ZhangJ,LiuX,LiS,WangQ,DiChen,HuZ,YuT,DingJ,LiJ,YaoM,FanJ,HuangS,GaoQ#,ZhaoY#,HeX#.TheLINC01138drivesmalignanciesviaactivatingargininemethyltransferase5inhepatocellularcarcinoma.NatCommun.2018Apr20;9(1):1572.
(7)DuanM,HaoJ,CuiS,WorthleyDL,ZhangS,WangZ,ShiJ,LiuL,WangX,KeA,CaoY,XiR,ZhangX,ZhouJ,FanJ#,LiC#,GaoQ#.DiversemodesofclonalevolutioninHBV-relatedhepatocellularcarcinomarevealedbysingle-cellgenomesequencing.CellRes.2018Mar;28(3):359-373.
(8)MaLJ,WangXY,DuanM,LiuLZ,ShiJY,DongLQ,YangLX,WangZC,DingZB,KeAW,CaoY,ZhangXM,ZhouJ,FanJ#,GaoQ#.Telomerelengthvariationintumorcellsandcancer-associatedfibroblasts:potentialbiomarkerforhepatocellularcarcinoma.JPathol.2017Dec;243(4):407-417.
(9)GaoQ,WangZC,DuanM,LinYH,ZhouXY,WorthleyDL,WangXY,NiuG,XiaY,DengM,LiuLZ,ShiJY,YangLX,ZhangS,DingZB,ZhouJ,LiangCM,CaoY,XiongL,XiR,ShiYY,FanJ.CellCultureSystemforAnalysisofGeneticHeterogeneityWithinHepatocellularCarcinomasandResponsetoPharmacologicAgents.Gastroenterology.2017Jan;152(1):232-242.e4.
(10)WangZC*,GaoQ*,ShiJY,GuoWJ,YangLX,LiuXY,LiuLZ,MaLJ,DuanM,ZhaoYJ,WuYN,GaoDM,WangXY,ShiGM,DingZB,KeAW,TangQQ,CaoY,ZhouJ,FanJ.ProteintyrosinephosphatasereceptorSactsasametastaticsuppressorinhepatocellularcarcinomabycontrolofepithermalgrowthfactorreceptor-inducedepithelial-mesenchymaltransition.Hepatology.2015Oct;62(4):1201-14.
(11)YangLX*,GaoQ*,ShiJY,WangZC,ZhangY,GaoPT,WangXY,ShiYH,KeAW,ShiGM,CaiJB,LiuWR,DuanM,ZhaoYJ,JiY,GaoDM,ZhuK,ZhouJ,QiuSJ,CaoY,TangQQ,FanJ.Mitogen-activatedproteinkinasekinasekinase4deficiencyinintrahepaticcholangiocarcinomaleadstoinvasivegrowthandepithelial-mesenchymaltransition.Hepatology.2015Dec;62(6):1804-16.
(12)GaoQ,WangXY,ZhouJ,FanJ.Heterogeneityofintermediate-stageHCCnecessitatespersonalizedmanagementincludingsurgery.NatRevClinOncol.2015Jan;12(1):10.
(13)GaoQ,WangXY,ZhouJ,FanJ.MultiplecarcinogenesiscontributestotheheterogeneityofHCC.NatRevGastroenterolHepatol.2015Jan;12(1):13.
(14)ShiJY,YangLX,WangZC,WangLY,ZhouJ,WangXY,ShiGM,DingZB,KeAW,DaiZ,QiuSJ,TangQQ,GaoQ#,FanJ#.CCchemokinereceptor-like1functionsasatumoursuppressorbyimpairingCCR7-relatedchemotaxisinhepatocellularcarcinoma.JPathol.2015Mar;235(4):546-58.
(15)GaoQ,ZhaoYJ,WangXY,GuoWJ,GaoS,WeiL,ShiJY,ShiGM,WangZC,ZhangYN,ShiYH,DingJ,DingZB,KeAW,DaiZ,WuFZ,WangH,QiuZP,ChenZA,ZhangZF,QiuSJ,ZhouJ,HeXH,FanJ.ActivatingmutationsinPTPN3promotecholangiocarcinomacellproliferationandmigrationandareassociatedwithtumorrecurrenceinpatients.Gastroenterology.2014May;146(5):1397-407.
(16)ShiJY*,GaoQ*,WangZC,ZhouJ,WangXY,MinZH,ShiYH,ShiGM,DingZB,KeAW,DaiZ,QiuSJ,SongK,FanJ.Margin-infiltratingCD20(+)Bcellsdisplayanatypicalmemoryphenotypeandcorrelatewithfavorableprognosisinhepatocellularcarcinoma.ClinCancerRes.2013Nov1;19(21):5994-6005.
(17)GaoQ,ZhaoYJ,WangXY,QiuSJ,ShiYH,SunJ,YiY,ShiJY,ShiGM,DingZB,XiaoYS,ZhaoZH,ZhouJ,HeXH,FanJ.CXCR6upregulationcontributestoaproinflammatorytumormicroenvironmentthatdrivesmetastasisandpoorpatientoutcomesinhepatocellularcarcinoma.CancerRes.2012Jul15;72(14):3546-56.
(18)GaoQ,WangXY,QiuSJ,YamatoI,ShoM,NakajimaY,ZhouJ,LiBZ,ShiYH,XiaoYS,XuY,FanJ.OverexpressionofPD-L1significantlyassociateswithtumoraggressivenessandpostoperativerecurrenceinhumanhepatocellularcarcinoma.ClinCancerRes.2009Feb1;15(3):971-9.
(19)GaoQ,QiuSJ,FanJ,ZhouJ,WangXY,XiaoYS,XuY,LiYW,TangZY.IntratumoralbalanceofregulatoryandcytotoxicTcellsisassociatedwithprognosisofhepatocellularcarcinomaafterresection.JClinOncol.2007Jun20;25(18):2586-93.