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仇缀百
2023-05-10 09:08
  • 仇缀百
  • 仇缀百 - 教授 博士生导师-复旦大学-药学院-个人资料

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近期论文


Highly selective and potent mu-opioid ligands by unexpected substituent on morphine skeleton. Bioorg, Med. Chem Lett. 2010, 20(1), 418-421.
The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad. J. Med. Chem., 2009, 52 (8): 2543-2549.
High-yield synthesis of androst-4-ene-3,6,17-trione and androst-4-ene-3b,6b-17b-triol. Organic Preparations And Procedures International, 2008, 40(4): 395-398.
Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on Amyloid-β aggregation. J. Med. Chem. 2008, 51(7): 2027-2036.
An efficient synthesis of 5 alpha-androst-1-ene-3,17-dione Steroids 2006, 71(13-14): 1088-1090.6、Investigation of the binding mode of (−)-meptazinol and bis-meptazinol derivatives on acetylcholinesterase using a molecular docking method. J. Mol. Modeling 2006, 12(4): 390-397.
QSAR study of 4-phenylpiperidine derivatives as mu opioid agonists by neutral network method. Eur. J. Med. Chem. 2006, 41(2): 226-232.
Synthesis and Relative Bioavailability of Meptazinol Benzoyl Esters as Prodrugs. Bioorg. Med. Chem. Lett. 2005, 15(10): 2607-2609.
Design, synthesis and bioavailability evaluation of a coumarin-based prodrug of meptazinol. Bioorg. Med. Chem. Lett. 2005, 15(22): 4953-4956.
Molecular modeling and 3D-QSAR studies on indolomorphinan derivatives as kappa opioid antagonists. Bioorg. Med. Chem. 2006, 14(3): 601-610

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