个人简历
教育、工作情况： 2002-2006年，清华大学化学系，理学学士； 2006-2011年，清华大学化学系，理学博士，导师为尉志武教授； 2011-2013年，美国密歇根大学化学系，博士后，导师为Prof. Zhan Chen（陈战教授）； 2013年2月加入东南大学生物科学与医学工程学院，2013年4月被评为教授，2013年12月被评为博士生导师。
研究领域
"""""（1）细胞及亚细胞（细胞膜、线粒体、溶酶体、细胞核等）荧光成像及分析； \r（2）生化检测、生物传感器； \r（3）细胞表面工程及其在生物医学领域（抗癌、抗菌、成像、生物检测等）的应用； \r（4）基于细胞自噬、癌细胞耐药性、肿瘤免疫疗法等思路寻找生物材料或生物分子的抗癌新应用。"
近期论文
(1) Xiaokai Chen#, Xiaodong Zhang#, Yuxin Guo, Ya-Xuan Zhu, Xiaoyang Liu, Zhan Chen,* and Fu-Gen Wu*. Smart Supramolecular “Trojan Horse”-Inspired Nanogels for Realizing Light-Triggered Nuclear Drug Influx in Drug-Resistant Cancer Cells. Adv. Funct. Mater. 2019, DOI: 10.1002/adfm.201807772. (Inside Back Cover) (2) Hao-Ran Jia#, Ya-Xuan Zhu#, Ke-Fei Xu, Guang-Yu Pan, Xiaoyang Liu, Ying Qiao, and Fu-Gen Wu*. Efficient cell surface labelling of live zebrafish embryos: wash-free fluorescence imaging for cellular dynamics tracking and nanotoxicity evaluation. Chem. Sci. 2019, DOI: 10.1039/C8SC04884C. (3) Wei Sun, Xiaodong Zhang, Hao-Ran Jia, Ya-Xuan Zhu, Yuxin Guo, Ge Gao, Yan-Hong Li, and Fu-Gen Wu*. Water-Dispersible Candle Soot-Derived Carbon Nano-Onion Clusters for Imaging-Guided Photothermal Cancer Therapy. Small 2019, DOI: 10.1002/smll.201804575. (4) Ge Gao#, Yao-Wen Jiang#, Hao-Ran Jia, and Fu-Gen Wu*. Near-infrared light-controllable on-demand antibiotics release using thermo-sensitive hydrogel-based drug reservoir for combating bacterial infection. Biomaterials 2019, 188, 83−95. (5) Xiaodong Zhang#, Xiaokai Chen#, Hong-Yin Wang, Hao-Ran Jia, and Fu-Gen Wu*. Supramolecular Nanogel-Based Universal Drug Carriers Formed by “Soft–Hard” Co-Assembly: Accurate Cancer Diagnosis and Hypoxia-Activated Cancer Therapy. Adv. Therap. 2019, DOI: 10.1002/adtp.201800140. (6) Ya-Xuan Zhu#, Hao-Ran Jia#, Guang-Yu Pan, Nathan W. Ulrich, Zhan Chen*, and Fu-Gen Wu*. Development of a Light-Controlled Nanoplatform for Direct Nuclear Delivery of Molecular and Nanoscale Materials. J. Am. Chem. Soc. 2018, 140(11), 4062−4070. (Cover) (7) Xiaokai Chen#, Xiaodong Zhang#, Liu-Yuan Xia, Hong-Yin Wang, Zhan Chen*, and Fu-Gen Wu*. One-Step Synthesis of Ultrasmall and Ultrabright Organosilica Nanodots with 100% Photoluminescence Quantum Yield: Long-Term Lysosome Imaging in Living, Fixed, and Permeabilized Cells. Nano Lett. 2018, 18(2), 1159−1167. (8) Yan-Wen Bao#, Xian-Wu Hua#, Xiaokai Chen, and Fu-Gen Wu*. Platinum-doped carbon nanoparticles inhibit cancer cell migration under mild laser irradiation: Multi-organelle-targeted photothermal therapy. Biomaterials 2018, 183, 30−42. (9) Hao-Ran Jia, Ya-Xuan Zhu, Ke-Fei Xu, Xiaoyang Liu, and Fu-Gen Wu*. Plasma membrane-anchorable photosensitizing nanomicelles for lipid raft-responsive and light-controllable intracellular drug delivery. J. Control. Release 2018, 286, 103−113. (10) Hao-Ran Jia, Yao-Wen Jiang, Ya-Xuan Zhu, Yan-Hong Li, Hong-Yin Wang, Xiaofeng Han, Zhi-Wu Yu, Ning Gu, Peidang Liu, Zhan Chen*, and Fu-Gen Wu*. Plasma membrane activatable polymeric nanotheranostics with self-enhanced light-triggered photosensitizer cell influx for photodynamic cancer therapy. J. Control. Release 2017, 255, 231−241. (11) Xiaodong Zhang,# Xiaokai Chen,# Jingjing Yang, Hao-Ran Jia, Yan-Hong Li, Zhan Chen,* and Fu-Gen Wu*. Quaternized Silicon Nanoparticles with Polarity-Sensitive Fluorescence for Selectively Imaging and Killing Gram-Positive Bacteria. Adv. Funct. Mater. 2016, 26, 5958−5970. (Front Cover & Highlighted by MaterialsViewsChina) (12) Xiaodong Zhang, Xiaokai Chen, Siqi Kai, Hong-Yin Wang, Jingjing Yang, Fu-Gen Wu* and Zhan Chen*. Highly Sensitive and Selective Detection of Dopamine Using One-Pot Synthesized Highly Photoluminescent Silicon Nanoparticles. Anal. Chem.2015, 87, 3360–3365. (13) Xiaodong Zhang, Fu-Gen Wu,* Peidang Liu, Ning Gu and Zhan Chen*. Enhanced Fluorescence of Gold Nanoclusters Composed of HAuCl4 and Histidine by Glutathione: Glutathione Detection and Selective Cancer Cell Imaging. Small2014, 10, 5170–5177. (Highlighted by MaterialsViewsChina)
