个人简历

西北师范大学博士，东南大学博士后，浸会大学、美国贝勒医学院和美国埃默里大学访问学者。

研究领域

生物信息学：表观基因组学、癌症基因组学。通过建立模型和算法，解析生物医学大数据(尤其是组学数据)，发现与癌症、退行性疾病等相关的分子、基因和通路，识别新的诊断标志物和治疗靶点；针对靶点，筛选治疗药物。

近期论文

1.Liu H.D., Luo K., Luo D. H., (2018). Guanosine monophosphate reductase 1 is a potential therapeutic target for Alzheimer’s disease, Scientific reports 8:2759. 2.Liu L.J., Xie J.M., Luo K., Sun X., Qin Steve Z.H., Liu H.D.* (2017). An approach of identifying differential nucleosome regions in multiple samples. BMC Genomics, 18:135. 3.Liu H.D., Luo K., Zhou Z.K., Mu Y., Wan Y.K. (2014). Histone chaperone Chz1 facilitates the disfavoring property of Spt16 to H2A.Z-containing genes in Saccharomyces cerevisiae. Biochem. J. 460, 387-397. 4.Liu H.D., Duan X.Y., Yu S.X., Sun X. (2011). Analysis of nucleosome positioning determined by DNA helix curvature in the human genome. BMC Genomics. 12:72. 5.Liu H.D., Wu J.S., Xie J.M., Yang X.N., Lu Z.H., Sun X. (2008). Characteristics of nucleosome core DNA and their applications in predicting nucleosome positions, Biophys. J. 94(12), 4597-4604.