个人简历

顾宁教授，教育部长江学者特聘教授，国家杰出青年基金获得者。 现任江苏省生物材料与器件重点实验室主任、东南大学纳米科学与技术研究中心主任。 曾任东南大学生物科学与医学工程学院院长、国家纳米科技重大专项专家委员会纳米生物与医药专家组成员、国家中长期规划“战略高技术与高新技术产业化研究专题组”成员、担任国家纳米科技协调指导委员会成员、国家重大科学研究计划“纳米研究”专家组专家、教育部留学回国人员科研启动基金评审专家、中国真空学会表面与纳米科学专委会副主任委员、中国生物医学工程学会常务理事、江苏省生物医学工程学会理事长 及 纳米医药专业委员会主任委员、江苏省新材料创新示范工程专家组专家等。

研究领域

"""""从事分子功能材料薄膜、纳米加工以及纳米材料制备、表征、及其在生物医（药）学领域中的应用研究。完成并正在承担十多项国家级及部省级科研项目，其中在生物纳米结构的扫描力显微术表征、生物医学纳米材料制备与构效关系研究以及原型纳米器件研制等方面的主要结果，包括在国内最早采用改装电子束装置制备出线宽小于70纳米的结构；在国际上采用原子力显微镜较系统地研究了人体腰椎间盘组织中的胶原等生物组织的纳米结构及其与相关病症，如腰椎间盘突出等相关的原因，并相继开展对生物杆状纳米结构进行了结构结合力学模量测量分析的研究；研究制备出一系列磁性纳米材料，研究将其应用与临床诊断与治疗肿瘤的功能、相关器械以及设备;研制出尖端直径纳米量级以及锥角可控的光纤探针与热电偶，可望在超高灵敏度生物检测方面获得应用等。目前主要研究兴趣还包括单分子与单细胞检测、磁性纳米材料与器件的生物医学应用、分子与生物纳米器件及其生物医学应用等。"

近期论文

Zhichao Lou*, He Han, Ming Zhou, Jinfeng Wan, Qian Sun, Xiaoyan Zhou, Ning Gu*, Fabrication of Magnetic Conjugation Clusters via Intermolecular Assembling for Ultrasensitive Surface Plasmon Resonance (SPR) Detection in a Wide Range of Concentrations, Analytical chemistry 2017.\r
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Yijun Liang, Hui Yu, Guodong Feng, Linlin Zhuang, Wei Xi, Ming Ma, Jun Chen*, Ning Gu*, Yu Zhang*, High-Performance Poly(lactic-co-glycolic acid)-Magnetic Microspheres Prepared by Rotating Membrane Emulsification for Transcatheter Arterial Embolization and Magnetic Ablation in VX2 Liver Tumors, ACS applied materials & interfaces 2017.\r
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Ling Chen, Jun Xie, Haoan Wu, Fengchao Zang, Ming Ma, Zichun Hua*, Ning Gu*, Yu Zhang*, Improving sensitivity of magnetic resonance imaging by using a dual-targeted magnetic iron oxide nanoprobe, Colloids and Surfaces B: Biointerfaces 2017, 161, 339-346.\r
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Zuoheng Zhang, Xubo Lin, Ning Gu*, Effects of temperature and PEG grafting density on the translocation of PEGylated nanoparticles across asymmetric lipid membrane, Colloids and Surfaces B: Biointerfaces 2017, 160(1), 92-100.\r
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Fengguo Fan, Jia Liu, Jianfei Sun*, Peng Wang, Ning Gu*, Magnetic energy-based understanding the mechanism of magnetothermal anisotropy for macroscopically continuous film of assembled Fe3O4 nanoparticles, AIP Advances 2017, 7(8), 085109.\r
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Yan Yang, Qiwei Wang, Lina Song, Xuan Liu, Peng Zhao, Feimin Zhang, Ning Gu*, Jianfei Sun*, Uptake of magnetic nanoparticles for adipose-derived stem cells with multiple passage numbers, SCIENCE CHINA Materials 2017, 60(9), 892-902.\r
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Haoan Wu, Lina Song, Ling Chen, Yixin Huang, Yang Wu, Fengchao Zang, Yanli An, Hanbai Lyu, Ming Ma, Jun Chen, Ning Gu*, Yu Zhang*, Injectable thermosensitive magnetic nanoemulsion hydrogel for multimodal-imaging-guided accurate thermoablative cancer therapy, Nanoscale 2017, 9(42), 16175-16182.\r
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Fei Xiong*, Ke Hu, Haol Yu, Lijun Zhou, Lina Song, Yu Zhang, Xiuhong Shan, Jianping Liu, Ning Gu*, A Functional Iron Oxide Nanoparticles Modified with PLA-PEG-DG as Tumor-Targeted MRI Contrast Agent, Pharmaceutical Research 2017, 34(8), 1683-1692.\r
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Jilai Tian, Caiyun Yan, Kunliang Liu, Juan Tao, Zhenchao Guo, Jianping Liu, Yu Zhang, Fei Xiong*, Ning Gu*., Paclitaxel-Loaded Magnetic Nanoparticles: Synthesis, Characterization, and Application in Targeting, Journal of Pharmaceutical Sciences 2017, 106(8), 2115-2122.\r
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Dewen Ye, Qiwei Wang, Weiguo Zhang, Jianfei Sun and Ning Gu*, Recent progress in magnetic labeling for stem cell, Chinese Science Bulletin 2017, 62(20), 2301-2311.\r
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Yang Liu, Mingxi Li, Fang Yang, Ning Gu, Magnetic drug delivery systems, SCIENCE CHINA Materials 2017, 60(6), 471-486.\r
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Yue Zhang, Zhichao Lou, Xubo Lin, Qiwei Wang, Meng Cao and Ning Gu*. , Optimizing purification process of MIM-I-BAR domain by introducing atomic force microscope and dynamics simulations, Colloids and Surfaces B: Biointerfaces 2017, 157, 391-397.\r
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Yijun Liang, Fengguo Fan, Ming Ma, Jianfei Sun, Jun Chen, Yu Zhang*, Ning Gu*, Size-Dependent Electromagnetic Properties and the Related Simulations of Fe3O4 Nanoparticles Made by Microwave-Assisted Thermal Decomposition, Colloids and Surfaces A: Physicochemical and Engineering Aspects 2017, 530(5), 191-199.\r
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Tuantuan Wang, Chuxiao Yuan, Bingyang Dai, Yang Liu, Mingxi Li, Zhenqiang Feng, Qing Jiang, Zhihong Xu, Ningwei Zhao, Ning Gu* and Fang Yang*, Click chemistry-mediated rapid microbubble catching for acute thrombus ultrasound molecular imaging, ChemBioChem 2017, 18(14), 1364–1368.\r
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Yuwei Zhou, Ke Hu, Zhaobin Guo, Kun Fang, Xing Wang, Fang Yang, Ning Gu*, PLLA microcapsules combined with silver nanoparticles and chlorhexidine acetate showing improved antibacterial effect, Materials Science and Engineering: C 2017, 78, 349-353.\r
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Shijia Tang, Ke Hu, Jianfei Sun, Yang Li, Zhaobin Guo, Mei Liu, Qi Liu, Feimin Zhang* and Ning Gu*, High quality multicellular tumor spheroid induction platform based on anisotropic magnetic hydrogel , ACS Applied Materials & Interfaces 2017, 9(12), 10446-10452.\r
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Lingying Zhu, Dawei Guo, Lili Sun, Zhihai Huang, Xiuyan Zhang, Wenjuan Ma, Jie Wu, Lun Xiao, Yun Zhao, Ning Gu*, Activation of autophagy by elevated reactive oxygen species rather than released silver ions promotes cytotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in hematopoietic cells, Nanoscale 2017, 9(17), 5489-5498.\r
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陈博，顾宁*, 药用铁基纳米材料及其发展前景, 中国材料进展 2017, 36(3), 211-218.\r
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Lushen Li, Shaneen S. Baxter, Ning Gu, Min Ji, Xi Zhan*, Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitination and interaction with small Rab GTPases, Journal of Cell Science 2017, 130(8), 1475-1485.\r
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Wei Zhang, Jinlai Dong, Yang Wu, Peng Cao, Lina Song, Ming Ma, Ning Gu*, Yu Zhang* , Shape-dependent enzyme-like activity of Co3O4 nanoparticles and their conjugation with his-tagged EGFR single-domain antibody, Colloids and Surfaces B: Biointerfaces 2017, 154, 55–62.