个人简历

教育经历
1991.9 -- 1994.7
崂山一中 无
2003.3 -- 2009.7
大连理工大学 生物化工 博士
1998.9 -- 2001.3
大连轻工业学院 发酵工程 硕士
1994.9 -- 1998.7
山东师范大学 食品科学与工程 学士
工作经历
2013.1 -- 至今
大连理工大学 副教授
2005.1 -- 2012.12
大连理工大学 讲师
2001.4 -- 2004.12
大连理工大学 助教

专利
一种利用微量通气提高菌株对微生物抗性的方法（授权）
一种提高酿酒酵母对纤维素水解液抑制物耐受性的方法（授权）
一种来源于马克斯克鲁维酵母的高表达启动子及其表达系统（授权）
一种来源于马克斯克鲁维酵母的烷基过氧化物还原酶和硫氧还蛋白还原酶及其应用（授权）
一株具有广谱抗菌活性的海洋链霉菌S187
一种重组酿酒酵母发酵菊芋生产乙醇的方法
著作成果
Advances in Feedstock Conversion Technologies for Alternative Fuels and Bioproducts
科研项目
重金属切流吸附柱中支撑体加工与性能指标测试, 企事业单位委托科技项目, 2018/04/27-2018/12/31, 完成
化学品生物转化过程与装备-菊芋块茎生产乙醇的CBP技术, 2012/02/29, 完成
蛋白表面展示絮凝酿酒酵母高效生产丙谷二肽, 企事业单位委托科技项目, 2016/10/27-2019/10/27, 进行
基于辅酶工程的纤维素水解液抑制物脱毒策略及混合糖发酵, 其他课题, 2016/04/14-2018/10/15, 完成
基于中泰农业生产及加工废弃物生产燃料乙醇基础研究, 国家自然科学基金项目, 2015/12/01, 完成
重金属吸附材料的非特异性吸附性能与重金属脱落测试, 企事业单位委托科技项目, 2015/12/09-2016/05/31, 完成
科研奖励
科技进步奖
优秀教学成果奖
大连市自然科学优秀学术论文
辽宁省自然科学学术成果奖
其他奖励
教学质量优良奖 （2019年）
校教学成果优良奖 （2017年）

研究领域

研究方向
（1）生物能源
（2）微生物代谢工程
（3）合成生物学""

近期论文

[1] Tian, Qizhe,Ye, Junwei,Yuan, Wenjie,Zhang, Siqi,Shi, Lei,Zhong, Jianchu,Ning, Guiling.Highly effective antibacterial activity of lithium-dopedmagnesium oxide particles synthesized by the microwave-assisted hydrothermal route[J],POWDER TECHNOLOGY,2020,371:130-141
[2] Du, Cong,Li, Yimin,Zong, Han,Yuan, Tangguo,Yuan, Wenjie,Jiang, Yu.Production of bioethanol and xylitol from non -detoxified corn cob via a two-stage fermentation strategy[J],BIORESOURCE TECHNOLOGY,2020,310
[3] Gao, Jiaoqi,Yuan, Wenjie,Li, Yimin,Xiang, Ruijuan,Hou, Shengbo,Zhong, Shijun,Bai, Fengwu.Transcriptional analysis of Kluyveromyces marxianus for ethanol production from inulin using consolidated bioprocessing technology[J],BIOTECHNOLOGY FOR BIOFUELS,2015,8(1):115
[4] Du, Cong,Li, Yinmin,Zhao, Xiaoyang,Pei, Xuze,Yuan, Wenjie,Bai, Fengwu,Jiang, Yu.The production of ethanol from lignocellulosic biomass by Kluyveromyces marxianus CICC 1727-5 and Spathaspora passalidarum ATCC MYA-4345[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2019,103(6):2845-2855
[5] Li, Yi-Min,Gao, Jiao-Qi,Pei, Xu-Ze,Du, Cong,Fan, Chao,Yuan, Wen-Jie,Bai, Feng-Wu.Production of l-alanyl-l-glutamine by immobilized Pichia pastoris GS115 expressing -amino acid ester acyltransferase[J],MICROBIAL CELL FACTORIES,2019,18(1):27
[6] Du Cong,Li Yinmin,Zhao Xiaoyang,Pei Xuze,Yuan Wenjie,Bai Fengwu,Jiang Yu.The production of ethanol from lignocellulosic biomass by Kluyveromyces marxianus CICC 1727-5 and Spathaspora passalidarum ATCC MYA-4345[J],Applied microbiology and biotechnology,2019,103(6):2845-2855
[7] 袁文杰,姬芳玲,孜力汗,贾凌云.新工科形势下的生产实习与管理模式探索[J],高校生物学教学研究（电子版）,2018,8(6):31-34
[8] 高洁,李益民,杜聪,裴绪泽,卢慧敏,赵孝阳,袁文杰.褐藻胶裂解酶基因的克隆表达与酶学性质[J],生物工程学报,2018,34(7):1178-1188
[9] 孜力汗,杨君,袁文杰,贾凌云,高晓蓉.生物工程专业实验自主学习开放教学改革[J],实验科学与技术,2018,16(5):139-144,169
[10] 孜力汗,贾凌云,杨君,修志龙,包永明,袁文杰,牟英,唐颖.通过科研与教学的结合建设生物工程专业校内实习实训基地[J],化工高等教育,2018,35(3):75-81
[11] 吕阳,袁文杰,刘涛.Experimental study of fungal release characteristics in central air conditioning systems[A],2018
[12] Li, Yimin,Yuan, Wenjie,Gao, Jiaoqi,Fan, Chao,Wu, Wenzhong,Bai, Fengwu.Production of L-alanyl-L-glutamine by recycling E. coli expressing alpha-amino acid ester acyltransferase[J],BIORESOURCE TECHNOLOGY,2017,245(,SI):1603-1609
[13] Li, Jinmei,Jiang, Yu,Yan, Gonghong,Liu, Sichi,Jiang, Tong,Zhong, Mingming,Yuan, Wenjie,Chen, Shaoxian,Zheng, Yin,Jiang, Yong.Target of rapamycin complex 1 and Tap42-associated phosphatases are required for sensing changes in nitrogen conditions in the yeast Saccharomyces cerevisiae[J],MOLECULAR MICROBIOLOGY,2017,106(6):938-948
[14] 冯华良,高教琪,侯胜博,李益民,袁文杰.ORP调控对马克斯克鲁维酵母发酵纤维素水解液的影响[J],化工学报,2017,68(11):4279-4287
[15] Gao, Jiaoqi,Yuan, Wenjie,Li, Yimin,Bai, Fengwu,Jiang, Yu.Synergistic effect of thioredoxin and its reductase from Kluyveromyces marxianus on enhanced tolerance to multiple lignocellulose-derived inhibitors[J],MICROBIAL CELL FACTORIES,2017,16(1):181
[16] Gao, Jiaoqi,Yuan, Wenjie,Li, Yimin,Bai, Fengwu,Jiang, Yu.Characterization of inulinase promoter from Kluyveromyces marxianus for intensive protein expression in industrial biotechnology[J],FEMS YEAST RESEARCH,2017,17(6)
[17] Lv, Yang,Hu, Guangyao,Wang, Chunyang,Yuan, Wenjie,Wei, Shanshan,Gao, Jiaoqi,Wang, Boyuan,Song, Fangchao.Actual measurement, hygrothermal response experiment and growth prediction analysis of microbial contamination of central air conditioning system in Dalian, China[J],SCIENTIFIC REPORTS,2017,7:44190
[18] Gao, Jiaoqi,Feng, Hualiang,Yuan, Wenjie,Li, Yimin,Hou, Shengbo,Zhong, Shijun,Bai, Fengwu.Enhanced fermentative performance under stresses of multiple lignocellulose-derived inhibitors by overexpression of a typical 2-Cys peroxiredoxin from Kluyveromyces marxianus[J],BIOTECHNOLOGY FOR BIOFUELS,2017,10(1):79
[19] Yuan, Wenjie,Guo, Shuguang,Gao, Jiaoqi,Zhong, Mingming,Yan, Gonghong,Wu, Wangmeng,Chao, Yapeng,Jiang, Yu.General Control Nonderepressible 2 (GCN2) Kinase Inhibits Target of Rapamycin Complex 1 in Response to Amino Acid Starvation in Saccharomyces cerevisiae[J],JOURNAL OF BIOLOGICAL CHEMISTRY,2017,292(7):2660-2669
[20] Khatun, M. Mahfuza,Liu, Chen-Guang,Zhao, Xin-Qing,Yuan, Wen-Jie,Bai, Feng-Wu.Consolidated ethanol production from Jerusalem artichoke tubers at elevated temperature by Saccharomyces cerevisiae engineered with inulinase expression through cell surface display[J],JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY,2017,44(2):295-301
[21] 侯胜博,冯华良,高教琪,李益民,袁文杰,白凤武.马克斯克鲁维酵母的木糖和阿拉伯糖发酵[J],生物工程学报,2017,33(6):923-935
[22] 袁文杰.Synergistic efect of thioredoxin and its reductase from Kluyveromyces marxianus on enhanced tolerance to multiple lignocellulose-derived inhibitors[J],Microbial Cell Factories,2017,16:181-194
[23] 吕阳,袁文杰.大连市某场馆集中式空调系统微生物污染实态、热湿响应及生长模拟预测分析[A],2017
[24] 袁文杰.Production of L-alanyl-L-glutamine by recycling E. coli expressing[J],Bioresource Technology,2017,245:1603-1609
[25] 袁文杰,钟世钧.Enhanced fermentative performance under stresses of multiple lignocellulose-derived inhibitorsby overexpression of a typical 2-Cys peroxiredoxin from Kluyveromyces marxianus[J],Biotechnology for Biofuels,2017,10:79-92
[26] 袁文杰.General Control Nonderepressible 2 (GCN2) Kinase Inhibits Target of Rapamycin[J],THE JOURNAL OF BIOLOGICAL CHEMISTRY,2017,292(7):2660-2669
[27] Gao, Jiaoqi,Yuan, Wenjie,Li, Yimin,Bai, Fengwu,Zhong, Shijun,Jiang, Yu.Application of redox potential control to improve ethanol productivity from inulin by consolidated bioprocessing[J],PROCESS BIOCHEMISTRY,2016,51(10):1544-1551
[28] Hu, Kejin,Guo, Shuguang,Yan, Gonghong,Yuan, Wenjie,Zheng, Yin,Jiang, Yu.Ubiquitin regulates TORC1 in yeast Saccharomyces cerevisiae[J],MOLECULAR MICROBIOLOGY,2016,100(2):303-314
[29] Wu, Youduo,Xue, Chuang,Chen, Lijie,Yuan, Wenjie,Bai, Fengwu.Synergistic effect of calcium and zinc on glucose/xylose utilization and butanol tolerance of Clostridium acetobutylicum[J],FEMS MICROBIOLOGY LETTERS,2016,363(5):fnw023
[30] 袁文杰.Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia[J],The Journal of Biological Chemistry,2016,291(22):11689-11697
[31] 袁文杰,白凤武,钟世钧.Application of redox potential control to improve ethanolproductivity from inulin by consolidated bioprocessing[J],Process Biochemistry,2016,51(7):1544-1551
[32] 袁文杰,蒋羽.Ubiquitin regulates TORC1 in yeast Saccharomyces[J],Molecular Microbiology,2016,100(2):303-314
[33] Wu, You-Duo,Xue, Chuang,Chen, Li-Jie,Yuan, Wen-Jie,Bai, Feng-Wu.Improvements of Metabolites Tolerance in Clostridium acetobutylicum by Micronutrient Zinc Supplementation[J],BIOTECHNOLOGY AND BIOPROCESS ENGINEERING,2016,21(1):60-67
[34] Lv, Yang,Wang, Chunyang,Yuan, Wenjie,Wei, Shanshan,Gao, Jiaoqi,Wang, Boyuan,Song, Fangchao.Actual measurement and analysis on microbial contamination in central air conditioning system at a venue in Dalian, China[A],8th International Cold Climate HVAC Conference,2015,146:146-153
[35] Gao, Jiaoqi,Yuan, Wenjie,Kong, Liang,Xiang, Ruijuan,Zhong, Shijun.Efficient ethanol production from inulin by two-stage aerate strategy[J],BIOMASS & BIOENERGY,2015,80:10-16
[36] 陈丽杰,汤晓燕,袁文杰,王晓珊.响应面分析法优化絮凝酵母SPSC01去除Cr(Ⅵ)[J],环境工程学报,2015,9(8):3773-3779
[37] 韩锡铜,高教琪,陈丽杰,袁文杰,白凤武.Kluyveromyces marxianus发酵己糖和戊糖生产乙醇[J],生物加工过程,2015,1:6-11
[38] 李益民,高教琪,袁文杰,相瑞娟,侯胜博.菊粉酶基因的异源表达、分离纯化及酶学性质[J],生物工程学报,2015,31(5):670-681
[39] 袁文杰,钟世钧.Efficient ethanol productions from inulin by two-stage aerate strategy[J],Biomass and Bioenergy,2015,8:10-15
[40] 相瑞娟,尹思静,侯胜博,袁文杰.菊芋秸秆的稀酸水解及乙醇发酵[J],现代化工,2015,35(5):81-84
[41] 李勇昊,张晓月,程诚,熊亮,袁文杰,赵心清,白凤武.菊芋全植株生产燃料乙醇的工艺探讨[J],生物产业技术,2014,6:23-29
[42] 高教琪,袁文杰,陈丽杰,白凤武.菊芋CBP乙醇发酵过程关键因素的研究[A],2014,1-2
[43] 汤晓燕,陈丽杰,袁文杰.金属硫蛋白应用于重金属吸附的研究进展[J],现代化工,2014,34(6):32-36,38
[44] 高教琪,韩锡铜,孔亮,袁文杰,王娜,白凤武.马克斯克鲁维酵母在工业生物技术中的应用[J],中国生物工程杂志,2014,34(2):109-117
[45] Lv Yang,Fu Bai-lin,Yuan Wen-jie,Hu Wen-ju.Study on Thermal Response of Fungal Microorganisms in Air Conditioning System[J],JOURNAL OF PURE AND APPLIED MICROBIOLOGY,2013,7(,SI):639-646
[46] Lv, Yang,Fu, Bailin,Yuan, Wenjie,Xie, An,Huang, Jinmu.Research on Fungal Microorganisms Growth Under Various Thermal Conditions[A],8th International Symposium on Heating, Ventilation, and AirConditioning (ISHVAC),2013,261(VOL. 1):487-496
[47] Yuan, Wen-Jie,Li, Nan-Nan,Zhao, Xin-Qing,Chen, Li-Jie,Kong, Liang,Bai, Feng-Wu.Engineering an industrial Saccharomyces cerevisiae strain with the inulinase gene for more efficient ethanol production from Jerusalem artichoke tubers[J],ENGINEERING IN LIFE SCIENCES,2013,13(5):472-478
[48] Yuan, WenJie,Zhao, Xinqing,Chen, Lijie,Bai, Fengwu.Improved ethanol production in Jerusalem artichoke tubers by overexpression of inulinase gene in Kluyveromyces marxianus[J],BIOTECHNOLOGY AND BIOPROCESS ENGINEERING,2013,18(4):721-727
[49] 孜力汗,刘晨光,王娜,袁文杰,白凤武.多种通气策略下的高浓度乙醇生产[J],中国生物工程杂志,2013,33(6):86-92
[50] 高教琪,袁文杰,陈丽杰,韩锡铜,白凤武.通气量和菊粉浓度对克鲁维酵母乙醇发酵的影响[J],生物工程学报,2013,29(3):325-332
[51] 汪立群,Alan K.Chang,袁文杰,白凤武.一种新的DyP-type过氧化物酶在大肠杆菌中的重组表达、纯化及鉴定[J],生物工程学报,2013,29(6):772-784
[52] 袁文杰,陈丽杰,孔亮,孜力汗,任剑刚,白凤武.rDNA介导的菊粉酶基因整合载体构建及在K.marxianus中应用[J],大连理工大学学报,2013,53(2):176-182
[53] 吕阳,袁文杰.Research on Fungal Microorganisms Growth Under Various Thermal Conditions[A],2013,487-496
[54] 吕阳,袁文杰,陈滨.空调系统真菌类微生物繁殖特性研究[J],微生物前沿,2013,2:78-82
[55] 高教琪,袁文杰,陈丽杰,白凤武.菊芋在生物工业中的应用[J],现代化工,2012,32(11):18-21,23
[56] 陈丽杰,商光来,袁文杰,吴又多,白凤武.利用核糖体工程选育丙酮丁醇菌提高丁醇产量[J],生物工程学报,2012,28(9):1048-1058
[57] 王娜,袁文杰,韩锡铜,白凤武,徐永平.纤维素降解产物对 Kluyveromyces marxianus 1727共发酵葡萄糖和木糖的影响[J],生物加工过程,2012,10(5):17-22
[58] 王娜,袁文杰,白凤武,李淑英.酵母菌木糖转运蛋白研究进展[J],中国农业科技导报,2012,14(4):24-30
[59] 王娜,刘晨光,袁文杰,葛旭萌,白凤武.氧化还原电位控制下自絮凝酵母高浓度乙醇发酵[J],化工学报,2012,63(4):1168-1174
[60] 杨梅,袁文杰,凤丽华.菊芋生料联合生物加工发酵生产燃料乙醇[J],安徽农业科学,2012,40(9):5438-5441
[61] 杨梅,袁文杰.搅拌桨对菊芋联合生物加工发酵生产燃料乙醇的影响[J],吉林化工学院学报,2012,29(1):71-75
[62] 袁文杰,陈丽杰,白凤武.燃料乙醇生产研究进展[J],生物过程,2012,2:81-88
[63] 陈丽杰,袁文杰.Effects of carbon sources, oxygenation and ethanol on the production of inulinase by Kluyveromyces marxianus YX01[J],Journal of Bioscience and Biotechnology,2012,1(2):155-161
[64] Yuan, W. J.,Chang, B. L.,Ren, J. G.,Liu, J. P.,Bai, F. W.,Li, Y. Y..Consolidated bioprocessing strategy for ethanol production from Jerusalem artichoke tubers by Kluyveromyces marxianus under high gravity conditions[J],JOURNAL OF APPLIED MICROBIOLOGY,2012,112(1):38-44
[65] 袁文杰,常宝垒,任剑刚,白凤武.菊芋生产燃料乙醇工艺路线探讨[J],可再生能源,2011,29(4):139-143
[66] 李楠楠,袁文杰,王娜,辛程勋,葛旭萌,白凤武.菊粉酶基因在酿酒酵母中的表达及乙醇发酵[J],生物工程学报,2011,27(7):1032-1039
[67] 袁文杰,常宝磊,任剑刚,刘建平,白凤武,Y.Y.Li.Consolidated bioprocessing strategy for ethanol production from Jerusalem artichoke tubers by Kluyveromyces marxianus under high gravity conditions[J],Journal Applied Microbiology,2011,112(1):38-44
[68] 孜力汗,张春明,任剑刚,袁文杰,陈丽杰.废糟液全循环对自絮凝酵母糖酵解途径关键酶、胁迫相关代谢物及胞内组分的影响[J],生物工程学报,2010,26(7):1019-1024
[69] Zhao, Xin-Qing,Li, Wen-Jun,Jiao, Wen-Ce,Li, Yan,Yuan, Wen-Jie,Zhang, Yu-Qin,Klenk, Hans-Peter,Suh, Joo-Won,Bai, Feng-Wu.Streptomyces xinghaiensis sp nov., isolated from marine sediment[J],INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY,2009,59(Pt 11):2870-2874
[70] 常宝磊,袁文杰,赵心清,任剑刚,白凤武.自絮凝颗粒酵母发酵菊芋汁生产乙醇[J],过程工程学报,2009,9(4):796-800
[71] Zhao, Xin-Qing,Jiao, Wen-Ce,Jiang, Bo,Yuan, Wen-Jie,Yang, Tian-Hong,Hao, Shuang.Screening and identification of actinobacteria from marine sediments: Investigation of potential producers for antimicrobial agents and type I polyketides[J],WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,2009,25(5):859-866
[72] 赵心清,袁文杰,白凤武.Streptomyces xinghaiensis sp. nov., a new marine actinomycete derived from a marine sediment sample[J],International Journal of System and Evolutionary Microbiology,2009,59(1):2870-2874
[73] 袁文杰,孜力汗,白凤武.高效液相色谱法测定克鲁维酵母菊芋发酵液中的乙醇、糖和有机酸类成分[J],分析化学,2009,37(6):850-854
[74] Zhao, X. Q.,Xue, C.,Ge, X. M.,Yuan, W. J.,Wang, J. Y.,Bai, F. W..Impact of zinc supplementation on the improvement of ethanol tolerance and yield of self-flocculating yeast in continuous ethanol fermentation[J],JOURNAL OF BIOTECHNOLOGY,2009,139(1):55-60
[75] Yuan, W. J.,Zhao, X. Q.,Ge, X. M.,Bai, F. W..Ethanol fermentation with Kluyveromyces marxianus from Jerusalem artichoke grown in salina and irrigated with a mixture of seawater and freshwater[J],JOURNAL OF APPLIED MICROBIOLOGY,2008,105(6):2076-2083
[76] 袁文杰,任剑刚,赵心清,白凤武.一步法发酵菊芋生产乙醇[J],生物工程学报,2008,24(11):1931-1936
[77] 袁文杰,赵心清,白凤武.一步法发酵菊芋产乙醇菌种的筛选及产酶条件、酶学性质的研究[J],生物加工过程,2008,6(6):25-29
[78] 薛闯,赵心清,葛旭萌,袁文杰,白凤武.锌离子对自絮凝酵母乙醇耐性和絮凝颗粒大小的影响[J],化工学报,2008,59(10):2582-2588
[79] Chang, Baolei,Yuan, Wenjie,Zhao, Xinqing,Bai, Fengwu.Ethanol production from Jerusalem artichoke juice using self-flocculating yeast[J],JOURNAL OF BIOTECHNOLOGY,2008,136:S272-S272
[80] Xue, Chuang,Zhao, Xinqing,Ge, Xumeng,Yuan, Wenjie,Bai, Fengwu.Modulation of floc size distribution and ethanol tolerance of the self-flocculating yeast by metal ion supplementation[J],JOURNAL OF BIOTECHNOLOGY,2008,136:S418-S418
[81] Yuan, Wenjie,Bai, Fengwu.Optimization of medium and process parameters for the production of inulinase from Kluyveromyces marxianus Y1[J],JOURNAL OF BIOTECHNOLOGY,2008,136:S317-S318
[82] Xue, Chuang,Zhao, Xin-Qing,Yuan, Wen-Jie,Bai, Feng-Wu.Improving ethanol tolerance of a self-flocculating yeast by optimization of medium composition[J],WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,2008,24(10):2257-2261
[83] 赵心清,矫文策,袁文杰,杨天虹,方玲玲.大连地区海泥样品中分离的五株海洋放线菌的研究[J],氨基酸和生物资源,2008,30(3):1-4,10
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