修志龙
近期热点
资料介绍
个人简历
个人简介Personal Profile1987年毕业于清华大学化工系,1990年硕士毕业留大连理工大学工作。1997年晋升副教授,2002年晋升教授。主要从事生物催化转化与生物分离方面的研究工作,承担了20余项科研项目,包括5项国家自然科学基金、5项“863”计划项目、1项“十五”科技攻关项目、3项“973”子课题等。在国内外学术期刊上共发表398篇论文(SCI收录200多篇),获授权中国发明专利53项、国际专利4项、美国专利1项,获辽宁省技术发明二等奖1项、自然科学三等奖2项, 主编、主译、参编国内外教材和专著10部。2003年评为辽宁省骨干青年教师,2005年教育部新世纪优秀人才基金获得者,2006年获得大连市优秀专家称号,2007年获宝钢教育基金优秀教师奖,2007年辽宁省百万人才工程百人层次人选,2009年辽宁省教学名师。连续三年(2014、2015、2016年)入选中国高被引学者榜单。教育部高等学校生物技术与生物工程专业教学指导委员会委员、辽宁省高校生物工程专业教学指导委员会主任委员、《过程工程学报》、《Engineering in Life Science》等6本学术杂志的编委。曾担任化工学院生物工程系副系主任、环境与生命学院党总支书记兼副院长、生命学院院长(2010-2015年)等党政职务。 教育经历1979.9 1982.8 山东省海阳一中 无1998.9 2000.7 大连理工大学 生物化工 博士1987.9 1990.7 大连理工大学 生物化工 硕士1982.9 1987.7 清华大学 化学工程 学士工作经历2010.3 至今 大连理工大学生命科学与技术学院 教授2002.10 2010.3 大连理工大学环境与生命学院 教授1997.10 2002.10 大连理工大学化工学院 副教授1992.12 1997.10 大连理工大学化工学院 讲师1990.3 1992.12 大连理工大学化工学院 助教专利 一种分离提纯发酵液中乙偶姻的方法 新鲜烟叶中多种产物的联产方法 一种改变通气条件调控产物的多细胞体系及发酵方法 一种利用烟叶残渣制备生物菌肥的方法 一种发酵生产乳酸的微生物混合菌群及发酵方法 一种砂轮用生物质基疏水填料的制备方法 著作成果 代谢工程的途径分析与优化 生物化学 成功的科研写作 生物工程与技术导论 多级生物加工系统优化原理与技术,第五章 1, 3-丙二醇生物合成过程及其优化与控制 Bioprocessing of renewable resources to commodity bioproducts 科研项目 基于生长和代谢特征的底物流加发酵生产1,3-丙二醇的控制方法, 国家自然科学基金项目, 2018/07/20-2030/03/31, 进行 微生物发酵甘油年产一万吨1,3-丙二醇, 企事业单位委托科技项目, 2018/06/22-2021/06/30, 进行 抗生素废酸水处理技术, 企事业单位委托科技项目, 2016/12/30-2018/06/30, 完成 海洋微生物菌群的特性及其工业应用, 其他课题, 2016/11/28, 进行 三种青霉素酰化酶的盐析萃取技术, 自选课题, 2016/07/08-2016/12/30, 进行 聚乙二醇洛塞那肽工艺优化及作用机制研究, 自选课题, 2016/07/09-2017/07/19, 完成 学术荣誉 教育部\研究领域
""生物催化与转化/生物分离工程/工业微生物组技术""""近期论文
[1]Dai, Jian-Ying,Yang, Yu,Dong, Yue-Sheng,Xiu, Zhi-Long.Solid-state Co-cultivation of Bacillus subtilis, Bacillus mucilaginosus, and Paecilomyces lilacinus Using Tobacco Waste Residue[J],APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,2020,190(3):1092-1105 [2]Yang Xiaozhe,Hu Wenzhong,Xiu Zhilong,Jiang Aili,Yang Xiangyan,Sarengaowa,Ji Yaru,Guan Yuge,Feng Ke.Microbial dynamics and volatilome profiles during the fermentation of Chinese northeast sauerkraut by Leuconostoc mesenteroides ORC 2 and Lactobacillus plantarum HBUAS 51041 under different salt concentrations[J],Food research international (Ottawa, Ont.),2020,130:108926 [3]Hou, Mengyang,Hu, Wenzhong,Xiu, Zhilong,Shi, Yusheng,Hao, Kexin,Cao, Duo,Guan, Yuge,Yin, Hanlin.Efficient enrichment of total flavonoids from Pteris ensiformis Burm. extracts by macroporous adsorption resins and in vitro evaluation of antioxidant and antiproliferative activities[J],JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICALAND LIFE SCIENCES,2020,1138:121960 [4]Hou, Mengyang,Sun, Jiao,Hu, Wenzhong,Wang, Aosheng,Xiu, Zhilong,Shi, Yusheng,Hao, Kexin,Sun, Xingsheng,Cao, Duo,Lu, Ruishan.Ultrasound-Assisted Extraction of Total Flavonoids from Pteris cretica L.: Process Optimization, HPLC Analysis, and Evaluation of Antioxidant Activity[J],ANTIOXIDANTS,2019,8(10) [5]Yuan, Jinlong,Xie, Jun,Liu, Chongyang,Teo, Kok Lay,Huang, Ming,Fan, Houming,Feng, Enmin,Xiu, Zhilong.Robust optimization for a nonlinear switched time-delay system with noisy output measurements using hybrid optimization algorithm[J],JOURNAL OF THE FRANKLIN INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS,2019,356(16):9730-9762 [6]Pan, Duo-Tao,Wang, Xu-Dong,Shi, Hong-Yan,Yuan, De-Cheng,Xiu, Zhi-Long.Ensemble optimization of microbial conversion of glycerol into 1, 3-propanediol by Klebsiella pneumoniae[J],JOURNAL OF BIOTECHNOLOGY,2019,301:68-78 [7]Dong, Yue-Sheng,Yang, Fan,Liu, Wen-Cai,Wang, Xu-Dong,Xing, Yan,Xiu, Zhi-Long.Separation and purification of wortmannilactone analogues by three-liquid-phase salting-out extraction coupled with column chromatography[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,224:397-404 [8]Li, Zhen,Yan, Ling,Zhou, Jinjie,Wang, Xiaoli,Sun, Yaqin,Xiu, Zhi-Long.Two-step salting-out extraction of 1,3-propanediol, butyric acid and acetic acid from fermentation broths[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,209:246-253 [9]Yuan Yuyu,Qu Kunli,Tan Demeng,Li Xiaoyu,Wang Lili,Cong Cong,Xiu Zhilong,Xu Yongping.Isolation and characterization of a bacteriophage and its potential to disrupt multi-drug resistant Pseudomonas aeruginosa biofilms[J],Microbial pathogenesis,2019,128:329-336 [10]Dai Jianying,Wang Zhuangfei,Xiu Zhi-Long.High production of optically pure (3R)-acetoin by a newly isolated marine strain of Bacillus subtilis CGMCC 13141[J],Bioprocess and biosystems engineering,2019,42(3):475-483 [11]Pan, Duo-Tao,Wang, Xu-Dong,Shi, Hong-Yan,Yuan, De-Cheng,Xiu, Zhi-Long.Dynamic flux balance analysis for microbial conversion of glycerol into 1,3-propanediol by Klebsiella pneumoniae[J],BIOPROCESS AND BIOSYSTEMS ENGINEERING,2018,41(12):1793-1805 [12]Wang, Xu-Dong,Wei, Ning-Ning,Wang, Shu-Chang,Yuan, Heng-Li,Zhang, Feng-Ying,Xiu, Zhi-Long.Kinetic Optimization and Scale-Up of Site-Specific Thiol-PEGylation of Loxenatide from Laboratory to Pilot Scale[J],INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,2018,57(44):14915-14925 [13]Sun, Yaqin,Zhang, Shuangshuang,Zhang, Xingxing,Zheng, Yafeng,Xiu, Zhilong.Ionic liquid-based sugaring-out and salting-out extraction of succinic acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,204:133-140 [14]Zhou, Jin-Jie,Shen, Jun-Tao,Wang, Xiao-Li,Sun, Ya-Qin,Xiu, Zhi-Long.Stability and oscillatory behavior of microbial consortium in continuous conversion of crude glycerol to 1,3-propanediol[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(19):8291-8305 [15]Dou, Shaohua,Chi, Naiyu,Zhou, Xinshang,Zhang, Qingfang,Pang, Fei,Xiu, Zhilong.Molecular cloning, expression, and biochemical characterization of a novel cold-active alpha-amylase from Bacillus sp dsh19-1[J],EXTREMOPHILES,2018,22(5):739-749 [16]Wang, Xudong,Wang, Shuchang,Pan, Duotao,Qin, Kairong,Yuan, Hengli,Zhang, Fengying,Sun, Yundong,Xiu, Zhilong.Combined optimization of N-terminal site-specific PEGylation of recombinant hirudin using response surface methodology and kinetic analysis[J],ENGINEERING IN LIFE SCIENCES,2018,18(8):611-621 [17]Dai, Jianying,Wang, Hui,Li, Yan,Xiu, Zhi-Long.Imidazolium ionic liquids-based salting-out extraction of 2,3-butanediol from fermentation broths[J],PROCESS BIOCHEMISTRY,2018,71:175-181 [18]Sun, Ya-Qin,Shen, Jun-Tao,Yan, Ling,Zhou, Jin-Jie,Jiang, Li-Li,Chen, Yang,Yuan, Jin-Long,Feng, Enmin,Xiu, Zhi-Long.Advances in bioconversion of glycerol to 1,3-propanediol: Prospects and challenges[J],PROCESS BIOCHEMISTRY,2018,71:134-146 [19]Zhang, Bowei,Xiu, Zhilong,Ma, Baiping,Yu, Liyan,Dong, Yuesheng,Sun, Wenlong,Yu, Na,Sun, Jin,Yu, Xiaoxia,Li, Xia,Xing, Yan,Yan, Dong,Ding, Qianzhi.Anti-diabetic effect of baicalein is associated with the modulation of gut microbiota in streptozotocin and high-fat-diet induced diabetic rats[J],JOURNAL OF FUNCTIONAL FOODS,2018,46:256-267 [20]Yan, Ling,Sun, Ya-Qin,Wang, Xu-Dong,Fu, Hong-Xin,Mu, Ying,Xiu, Zhi-Long.Partition behavior of monocarboxylic acids in salting-out extraction systems of monohydric alcohols and dipotassium phosphate[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,199:351-358 [21]孜力汗,贾凌云,杨君,修志龙,包永明,袁文杰,牟英,唐颖.通过科研与教学的结合建设生物工程专业校内实习实训基地[J],化工高等教育,2018,35(3):75-81 [22]胡春燕,王旭东,秦超,董悦生,修志龙.克拉维酸钾一步结晶工艺优化[J],高校化学工程学报,2018,32(4):910-917 [23]Dong, Zhenyu,Tan, Bing,Zhang, Yuduo,Yuan, Jinlong,Feng, Enmin,Yin, Hongchao,Xiu, Zhilong.Strong stability of an optimal control hybrid system in fed-batch fermentation[J],INTERNATIONAL JOURNAL OF BIOMATHEMATICS,2018,11(4) [24]Zhao Shan,Yang Fan,Liu Yang,Sun Dongsheng,Xiu Zhilong,Ma Xiaojun,Zhang Ying,Sun Guangwei.Study of chemical characteristics, gelation properties and biological application of calcium pectate prepared using apple or citrus pectin.[J],International journal of biological macromolecules,2018,109:180-187 [25]Xing, Yan,Chen, Chaonan,Sun, Wenlong,Zhang, Bowei,Sang, Yuanbin,Xiu, Zhilong,Dong, Yuesheng.An environment-friendly approach to isolate and purify glucan from spent cells of recombinant Pichia pastoris and the bioactivity characterization of the purified glucan[J],ENGINEERING IN LIFE SCIENCES,2018,18(4):227-235 [26]李敬达,余承洁,王仁军,付常振,修志龙,刘庆平.慢病毒介导CD36基因沉默细胞株的构建及其对caveolin-1蛋白表达的影响[J],生物工程学报,2018,34(01):110-121 [27]Zhao, Shan,Zhang, Ying,Liu, Yang,Yang, Fan,Xiu, Zhilong,Ma, Xiaojun,Sun, Guangwei.Preparation and optimization of calcium pectate beads for cell encapsulation[J],JOURNAL OF APPLIED POLYMER SCIENCE,2018,135(2) [28]杨晓哲,胡文忠,姜爱丽,修志龙.鲜切莴苣生理生化变化及其保鲜技术的研究进展[J],食品与发酵工业,2018,44(2):278-283 [29]鄢凌,傅宏鑫,王旭东,孙亚琴,戴建英,修志龙.生物基有机酸提取分离技术研究进展[J],过程工程学报,2018,18(1):1-10 [30]郑伟龙,Jingda Li,Xudong Wang,Yanping Yuan,张嘉宁,修志龙.Effects of Antarctic krill docosahexaenoic acid on MCF-7 cell migration and invasion induced by the interaction of CD95 and caveolin-1[J],Life Science,2018,192(2):270-277 [31]Zheng, Weilong,Li, Jingda,Wang, Xudong,Yuan, Yanping,Zhang, Jianing,Xiu, Zhilong.Effects of Antarctic krill docosahexaenoic acid on MCF-7 cell migration and invasion induced by the interaction of CD95 with caveolin-1[J],LIFE SCIENCES,2018,192:270-277 [32]Sun Wenlong,Zhang Bowei,Yu Xiaoxia,Zhuang Chunlin,Li Xia,Sun Jin,Xing Yan,Xiu Zhilong,Dong Yuesheng.Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice.[J],Phytomedicine : international journal of phytotherapy and phytopharmacology,2018,38:24-34 [33]Liu, Wen-Cai,Dong, Yue-Sheng,Ren, Yi-Xin,Hao, Ai-Yu,Yu, Sun,Shi, Xuan,Zhang, Xue-Qiang,Xing, Yan,Xiu, Zhi-Long,Cui, Yu.The activities of wortmannilactones against helminth electron transport chain enzymes, structure-activity relationships, and the effect on Trichinella spiralis infected mice.[J],The Journal of antibiotics,2018,71(8):731-740 [34]Jiang, Lili,Dai, Jianying,Sun, Yaqin,Xiu, Zhilong.The effects of ionic liquid 1-ethyl-3-methylimidazolium trifluoromethanesulfonate on the production of 1,3-propanediol from crude glycerol by microbial consortium.[J],Bioprocess and biosystems engineering,2018,41(8):1079-1088 [35]Zhu, Xi,Kliemann, Wolfgang,Li, Chunfa,Feng, Enmin,Xiu, Zhilong.Global behavior analysis for stochastic system of 1,3-PD continuous fermentation[J],COMMUNICATIONS IN NONLINEAR SCIENCE AND NUMERICAL SIMULATION,2017,53:228-248 [36]Wang, Xudong,Lv, Li,Qin, Kairong,Yuan, Hengli,Zhang, Fengying,Chen, Guohui,Xiu, Zhilong.Effects of linear and branched polyethylene glycol on PEGylation of recombinant hirudin: Reaction kinetics and in vitro and in vivo bioactivities[J],PROCESS BIOCHEMISTRY,2017,63:154-162 [37]Zhang, Bo-wei,Xing, Yan,Wen, Chen,Yu, Xiao-xia,Sun, Wen-long,Xiu, Zhi-long,Dong, Yue-sheng.Pentacyclic triterpenes as alpha-glucosidase and alpha-amylase inhibitors: Structure-activity relationships and the synergism with acarbose[J],BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2017,27(22):5065-5070 [38]余承洁,李敬达,修志龙,刘庆平.ox-LDL经由LOX-1受体对PPARγ-LXRα-ABCA1通路激活的作用研究[J],中国动脉硬化杂志,2017,25(10):978-984 [39]Sun, Wenlong,Sun, Jin,Zhang, Bowei,Xing, Yan,Yu, Xiaoxia,Li, Xia,Xiu, Zhilong,Dong, Yuesheng.Baicalein improves insulin resistance via regulating SOCS3 and enhances the effect of acarbose on diabetes prevention[J],JOURNAL OF FUNCTIONAL FOODS,2017,37:339-353 [40]Zhang, Bo-wei,Li, Xia,Sun, Wen-long,Xing, Yan,Xiu, Zhi-long,Zhuang, Chun-lin,Dong, Yue-sheng.Dietary Flavonoids and Acarbose Synergistically Inhibit alpha-Glucosidase and Lower Postprandial Blood Glucose[J],JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2017,65(38):8319-8330 [41]沈俊涛,修志龙.工业微生物的噬菌体感染与防治策略[J],生物工程学报,2017,33(12):1901-1912 [42]Dai, Jianying,Guan, Wentian,Ma, Linhui,Xiu, Zhilong.Salting-out extraction of acetoin from fermentation broth using ethyl acetate and K2HPO4[J],SEPARATION AND PURIFICATION TECHNOLOGY,2017,184:275-279 [43]张超蕾,周瑾洁,姜莉莉,王晓丽,朱甲名,权春善,修志龙.微生物组学及其应用研究进展[J],微生物学杂志,2017,37(4):74-81 [44]Zhou, Jin-Jie,Shen, Jun-Tao,Jiang, Li-Li,Sun, Ya-Qin,Mu, Ying,Xiu, Zhi-Long.Selection and characterization of an anaerobic microbial consortium with high adaptation to crude glycerol for 1,3-propanediol production[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2017,101(15):5985-5996 [45]Jiang Li-Li,Zhou Jin-Jie,Quan Chun-Shan,Xiu Zhi-Long.Advances in industrial microbiome based on microbial consortium for biorefinery.[J],Bioresources and bioprocessing,2017,4(1):11 [46]Zhang, Bo-wei,Sang, Yuan-bin,Sun, Wen-long,Yu, He-shui,Ma, Bai-ping,Xiu, Zhi-long,Dong, Yue-sheng.Combination of flavonoids from Oroxylum indicum seed extracts and acarbose improves the inhibition of postprandial blood glucose: In vivo and in vitro study[J],BIOMEDICINE & PHARMACOTHERAPY,2017,91:890-898 [47]杨琦,蒋志刚,冯恩民,尹洪超,修志龙.以函数为参量的间歇发酵非线性动力系统及其辨识[J],运筹学学报,2017,21(2):46-56 [48]Fu, Hongxin,Wang, Xudong,Sun, Yaqin,Yan, Ling,Shen, Juntao,Wang, Jufang,Yang, Shang-Tian,Xiu, Zhilong.Effects of salting-out and salting-out extraction on the separation of butyric acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2017,180:44-50 [49]Jiang, LiLi,Liu, HuiFang,Mu, Ying,Sun, YaQin,Xiu, ZhiLong.High tolerance to glycerol and high production of 1,3-propanediol in batch fermentations by microbial consortium from marine sludge[J],ENGINEERING IN LIFE SCIENCES,2017,17(6):635-644 [50]Yuan, Jinlong,Zhang, Yuduo,Ye, Jianxiong,Xie, Jun,Teo, Kok Lay,Zhu, Xi,Feng, Enmin,Yin, Hongchao,Xiu, Zhilong.Robust parameter identification using parallel global optimization for a batch nonlinear enzyme-catalytic time-delayed process presenting metabolic discontinuities[J],APPLIED MATHEMATICAL MODELLING,2017,46:554-571 [51]Li, Jingda,Xiu, Zhilong,Wang, Renjun,Yu, Chengjie,Chi, Yan,Qin, Jianzhong,Fu, Changzhen,Matsuura, Eiji,Liu, Qingping.The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPAR gamma[J],LIFE SCIENCES,2017,177:27-40 [52]Li, Na,Sun, Guangwei,Wang, Shujun,Wang, Yu,Xiu, Zhilong,Sun, Dongsheng,Guo, Xin,Zhang, Ying,Ma, Xiaojun.Engineering islet for improved performance by optimized reaggregation in alginate gel beads[J],BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY,2017,64(3):400-405 [53]窦少华,周新尚,迟乃玉,修志龙.海洋低温α-淀粉酶菌株Bacillus thuringiensis dsh19-1发酵条件研究[J],中国酿造,2017,36(4):36-39 [54]Wang, Xudong,Li, Xueqin,Zhao, Jun,Lv, Li,Qin, Kairong,Yuan, Hengli,Xiu, Zhilong.In situ PEGylation of recombinant hirudin on an anion exchange chromatography column[J],PROCESS BIOCHEMISTRY,2017,55:162-171 [55]Shen, Juntao,Lv, Li,Wang, Xudong,Xiu, Zhilong,Chen, Guoqiang.Comparative analysis of CRISPR-Cas systems in Klebsiella genomes[J],JOURNAL OF BASIC MICROBIOLOGY,2017,57(4):325-336 [56]胡春燕,秦超,王旭东,董悦生,修志龙,李树有,冯涛,王启斌.克拉维酸在乙酸乙酯中的稳定性[J],高校化学工程学报,2017,31(2):270-275 [57]Dai, Jian-Ying,Ma, Lin-Hui,Wang, Zhuang-Fei,Guan, Wen-Tian,Xiu, Zhi-Long.Sugaring-out extraction of acetoin from fermentation broth by coupling with fermentation[J],BIOPROCESS AND BIOSYSTEMS ENGINEERING,2017,40(3):423-429 [58]Sun, Wenlong,Sang, Yuanbin,Zhang, Bowei,Yu, Xiaoxia,Xu, Qinmin,Xiu, Zhilong,Dong, Yuesheng.Synergistic effects of acarbose and an Oroxylum indicum seed extract in streptozotocin and high-fat-diet induced prediabetic mice[J],BIOMEDICINE & PHARMACOTHERAPY,2017,87:160-170 [59]Fu, Hongxin,Yu, Le,Lin, Meng,Wang, Jufang,Xiu, Zhilong,Yang, Shang-Tian.Metabolic engineering of Clostridium tyrobutyricum for enhanced butyric acid production from glucose and xylose[J],METABOLIC ENGINEERING,2017,40:50-58 [60]Zheng, Weilong,Wang, Xudong,Cao, Wenjing,Yang, Bowen,Mu, Ying,Dong, Yuesheng,Xiu, Zhilong.E-configuration structures of EPA and DHA derived from Euphausia superba and their significant inhibitive effects on growth of human cancer cell lines in vitro[J],PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS,2017,117:47-53 [61]王路,刘涛,陈洋,孙亚琴,修志龙.基于傅里叶变换近红外光谱实时分析1,3-丙二醇发酵过程生物量的在线监测方法[J],生物工程学报,2017,33(1):68-78 [62]Sun, Wenlong,Xiu, Zhilong,Zhang, Bowei,Zheng, Haizhou,Zhuang, Chunlin,Li, Xia,Lu, Xinhua,Quan, Chunshan,Dong, Yuesheng,Zheng, Zhihui.Trivaric acid, a new inhibitor of PTP1b with potent beneficial effect on diabetes[J],LIFE SCIENCES,2017,169:52-64 [63]修志龙.The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ[J],LIfe Science,2017,177(1):27-40 [64]董悦生,修志龙.Pentacyclic triterpenes as α-glucosidase and α-amylase inhibitors: Structure-activity relationships and the synergism with acarbose[J],Bioorganic & Medicinal Chemistry Letters,2017,27:5065-5070 [65]董悦生,修志龙.Dietary Flavonoids and Acarbose Synergistically Inhibit ?-Glucosidase and Lower Postprandial Blood Glucose[J],Journal of Agricultural Food and Chemistry,2017,65:8319-8330 [66]董悦生,修志龙.E-configuration structures of EPA and DHA derived 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