伍会健
近期热点
资料介绍
个人简历
个人简介辽宁省“蛋白质修饰与疾病发生”重点实验室主任,辽宁省“分子生物学”创新团队负责人,大连市“蛋白质修饰与肿瘤分子生物学”重点实验室主任,大连理工大学创新团队负责人。先后获得辽宁省优秀科技工作者、“兴辽英才计划”创新领军人才、辽宁省“百千万人才工程”百人层次、辽宁省高校优秀人才支持计划、辽宁省第七批优秀专家、第三届大连市归国留学人员创业英才标兵、首届大连市优秀科技工作者等荣誉称号。长期担任Cell Death and Disease、Molular Cancer、中国生物化学与分子生物学报等国内外期刊审稿人。主要从事肿瘤分子生物学领域的教学、科研工作,在研究过程中,注重新的、有效的技术平台的建立和科学理论的提出,取得以下成果:1.肿瘤组织与正常组织的细胞具有不同的节律特征,寻找二者之间的差异,不仅可以探讨肿瘤发生、发展的机制,更为肿瘤的时间治疗提供理论依据。2.蛋白质的化学修饰是基因表达调控的重要一环。我们鉴定出多个蛋白质的多种修饰,并阐明调控蛋白质活性及功能的“分子开关”机制。 本人在Nature、及其旗下期刊Oncogene、Cell Death Dis、Sci Rep、Oncogenesis;分子生物学类著名期刊Can Lett、Mol Cancer、J Biol Chem、Cell Mol Life Sci、Mol Biol Cel、Biol Cell等杂志发表论文50余篇。论文被国际著名杂志Cell、Cancer Cell、NAT STRUCT MOL BIOL等他引达1000余次。作为第一完成人先后获得包括 “辽宁自然科学二等奖”、“辽宁医学科技奖一等奖”、“大连市科技进步一等奖”等多项奖励;作为第三完成人先后获得“国家自然科学二等奖”、“中华医学科技奖一等奖”、“高校自然科学一等奖”等。 共培养出博士后4人,毕业博士生14人,硕士生17人;目前在读博士生9人,硕士生8人。 教育经历2000.4 2003.3 九州大学理学部 分子生物学 博士1997.4 2000.3 九州大学理学部 分子生物学 硕士1984.7 1988.9 辽宁大学生物系 生物学 学士1981.9 1984.7 辽师附属高中 无工作经历2005.12 至今 大连理工大学2003.10 2005.11 北京大学医学部 博士后2003.4 2003.9 九州大学理学部 博士研究员1988.8 1997.3 大连市环保局 工程师、主任科员专利 一种蛇毒浮肿因子抑制蛋白的制备及其应用 一种乳腺癌抑癌蛋白的鉴定及其应用 著作成果 诺贝尔奖中的生命科学(下) 诺贝尔奖中的生命科学(上) 癌与DNA的秘密 细胞与分子生物学实验指南 分子生物学 科研项目 TCF21的SUMO化修饰在乳腺癌相关雌激素信号通路中的调控作用, 国家自然科学基金项目, 2016/08/17, 进行 分子生物学, 省、市、自治区科技项目, 2015/07/16-2017/12/29, 完成 乳腺癌中SIP蛋白的作用机理研究, 省、市、自治区科技项目, 2008/01/01, 完成 抗肿瘤生物工程药物P-DREE-M基因的研究和开发, 省、市、自治区科技项目, 2006/01/01, 完成 细颗粒物PM对人体健康的危害及对策研究, 其他课题, 2014/12/02, 进行 SUMO化修饰蛋白的功能研究, 2006/12/01-2008/12/31, 完成 科研奖励 辽宁省自然科学奖 大连市科技进步一等奖 辽宁省科学技术奖 大连市科技进步奖 辽宁省医学科技奖 国家自然科学二等奖 其他奖励 “兴辽英才计划”创新领军人才 (2018年) 辽宁省第七批优秀专家 (2018年) 辽宁省优秀科技工作者 (2014年) 首届“大连市优秀科技工作者”称号 (2013年) 大连市归国留学人员创业英才标兵 (2011年) 辽宁省高等学校优秀人才支持计划 (2010年)研究领域
蛋白质化学修饰与细胞的信号转导基因转录调控与肿瘤""近期论文
[1]Sun Dongsheng,Liu Yang,Wang Huihui,Deng Fei,Zhang Ying,Zhao Shan,Ma Xiaojun,Wu Huijian,Sun Guangwei.Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.[J],International journal of biological macromolecules,2018,109:1154-1163 [2]Chen Huan,Wang Miao,Wu Huijian,Xu Zhaowei,Li Xiahui,Yang Yangyang,Li Bowen,Li Yanan,Xia Kangkai,Wang Jian,Li Shujing.α-catenin SUMOylation increases IκBα stability and inhibits breast cancer progression[J],Oncogenesis,2018,7(3):28 [3]Jia Zhaojun,Wu Huijian,Wang Miao,Li Shujing,Li Xiahui,Bai Xiao-Yan,Xu Zhaowei,Yang Yangyang,Li Bowen,Li Yanan.U-box ubiquitin ligase PPIL2 suppresses breast cancer invasion and metastasis by altering cell morphology and promoting SNAI1 ubiquitination and degradation.[J],Cell death & disease,2018,9(2):63 [4]Xu, Zhaowei,Wu, Huijian,Yang, Yangyang,Li, Bowen,Li, Yanan,Xia, Kangkai,Yang, Yuxi,Li, Xiahui,Wang, Miao,Li, Shujing.Checkpoint suppressor 1 suppresses transcriptional activity of ERalpha and breast cancer cell proliferation via deacetylase SIRT1.[J],Cell death & disease,2018,9(5):559 [5]Wang, Miao,Yang, Yuxi,Xu, Jian,Bai, Wen,Ren, Xueli,Wu, Huijian.CircRNAs as biomarkers of cancer: a meta-analysis.[J],BMC cancer,2018,18(1):303 [6]Bai, Xiao-Yan,Chen, Huan,Wu, Huijian,Li, Shujing,Wang, Miao,Li, Xiahui,Yang, Yangyang,Xu, Zhaowei,Li, Bowen,Li, Yanan,Xia, Kangkai.Kruppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses human breast cancer invasion[J],CANCER LETTERS,2018,412(412):224-235 [7]Chen, Huan,Wang, Miao,Wu, Huijian,Xu, Zhaowei,Li, Xiahui,Yang, Yangyang,Li, Bowen,Li, Yanan,Xia, Kangkai,Wang, Jian,Li, Shujing.alpha-catenin SUMOylation increases IkappaBalpha stability and inhibits breast cancer progression.[J],Oncogenesis,2018,7(3) [8]Wang, Miao,Chen, Huan,Wu, Huijian,Li, Shujing,Xu, Zhaowei,Li, Xiahui,Yang, Yangyang,Li, Bowen,Li, Yanan,Guo, Jing.SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling[J],ONCOTARGET,2017,8(52):89692-89706 [9]郭静,曲鑫建,伍会健.肿瘤免疫疗法中免疫检查点的研究进展[J],生理科学进展,2017,48(4):287-293 [10]Sun Dongsheng,Liu Yang,Wu Hao,Ren Ying,Ma Xiaojun,Wu Huijian,Sun Guangwei.Effects of gelling bath on the physical properties of alginate gel beads and the biological characteristics of entrapped HepG2 cells.[J],Biotechnology and applied biochemistry,2017,65(2):263-273 [11]李霞辉,李淑晶,伍会健.近日节律对乳腺癌他莫昔芬耐药的影响[J],生命的化学,2017,37(3):313-318 [12]孙静静,王淼,伍会健.TRIM在肿瘤发生发展中的作用[J],中国细胞生物学学报,2017,39(1):106-113 [13]陈欢,王淼,伍会健.上皮-间质转化在肿瘤侵袭、转移及化疗耐药中的研究进展[J],中国细胞生物学学报,2017,39(7):978-983 [14]伍会健.Krüppel-like factor 9 Down-Regulates Matrix Metalloproteinase 9 Transcription and[J],Cancer Letters,2017,412:224-235 [15]苏启明,曲鑫建,伍会健.ELF5 在正常乳腺发育和乳腺肿瘤发生中的作用[J],生命科学研究,2017,21(3):262-267 [16]Li, Shujing,Wang, Miao,Qu, Xinjian,Xu, Zhaowei,Yang, Yangyang,Su, Qiming,Wu, Huijian.SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination[J],ONCOTARGET,2016,7(31):50507-50519 [17]Jiang, Xiao,Zhang, Mei,Bai, Xiao-Yan,Li, Shujing,Wu, Huijian.Association between 17q25.3-rs6465657 polymorphism and prostate cancer susceptibility: a meta-analysis based on 19 studies[J],ONCOTARGETS AND THERAPY,2016,9:4491-4503 [18]Ao, Xiang,Li, Shujing,Xu, Zhaowei,Yang, Yangyang,Chen, Min,Jiang, Xiao,Wu, Huijian.Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha[J],ONCOTARGET,2016,7(18):26220-26234 [19]李亚楠,白晓彦,伍会健.上皮间质转化抑制剂及其在抗肿瘤治疗中的应用[J],中国生物化学与分子生物学报,2016,32(11):1185-1191 [20]伍会健.TRIM在肿瘤发生发展中的作用[J],中国细胞生物学学报,2016,39(1):106-113 [21]伍会健.DEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the progression of cell cycle S phase[J],Science Foundation in China,2016,24(1):43-43 [22]伍会健.生物节律蛋白对乳腺癌发生发展的调控机制[A],2015年中国中西医结合学会时间生物医学专业委员会学术研讨暨换届会议,2015,74-74 [23]Bi, H.,Yang, Y.,Wu, H.,Li, S.,Qu, X.,Wang, M.,Bai, X.,Xu, Z.,Ao, X.,Jia, Z.,Jiang, X..DEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the progression of cell cycle S phase[J],CELL DEATH & DISEASE,2015,6(9):e1891 [24]Bai, Xiao-Yan,Qu, Xinjian,Jiang, Xiao,Xu, Zhaowei,Yang, Yangyang,Su, Qiming,Wang, Miao,Wu, Huijian.Association between Dietary Vitamin C Intake and Risk of Prostate Cancer: A Meta-analysis Involving 103,658 Subjects[J],JOURNAL OF CANCER,2015,6(9):913-921 [25]Li, Shen,Lv, Guojun,Wu, Huijian,Ma, Xiaojun,Zhang, Ying,Chen, Li,Li, Na,Xie, Hongguo,Guo, Xin,Zhao, Shan,Yu, Weiting,Lv, Yan.The relationship between the inflammatory response and cell adhesion on alginate-chitosan-alginate microcapsules after transplantation[J],JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2015,103(7):2333-2343 [26]Ao, Xiang,Liu, Ying,Bai, Xiao-Yan,Qu, Xinjian,Xu, Zhaowei,Hu, Gaolei,Chen, Min,Wu, Huijian.Association between EHBP1 rs721048(A > G) polymorphism and prostate cancer susceptibility: a meta-analysis of 17 studies involving 150,678 subjects[J],ONCOTARGETS AND THERAPY,2015,8:1671-1680 [27]姜潇,白晓彦,伍会健.PPARs在非酒精性脂肪性肝病发病机制中的作用[J],生理科学进展,2015,46(3):220-224 [28]Bai, Xiao-Yan,Li, Shujing,Wang, Miao,Qu, Xinjian,Hu, Gaolei,Xu, Zhaowei,Chen, Min,He, Guo-Wei,Wu, Huijian.Association of Monocyte Chemoattractant Protein-1 (MCP-1)-2518A > G Polymorphism with Susceptibility to Coronary Artery Disease: A Meta-Analysis[J],ANNALS OF HUMAN GENETICS,2015,79(3):173-187 [29]Ma, Cai-Xia,Zhou, Chun-Yan,Zou, Yunzeng,Nemer, Mona,Zhang, Shan-Feng,Bai, Xiaowen,Wu, Huijian,Zang, Ming-Xi,Song, Yang-Liu,Xiao, Liyun,Xue, Li-Xiang,Li, Wen-Juan,Laforest, Brigitte,Komati, Hiba,Wang, Wei-Ping,Jia, Zhu-Qing.EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner[J],CELLULAR AND MOLECULAR LIFE SCIENCES,2015,72(10):2005-2022 [30]Liu, Ying,Ao, Xiang,Jia, Zhaojun,Bai, Xiao-Yan,Xu, Zhaowei,Hu, Gaolei,Jiang, Xiao,Chen, Min,Wu, Huijian.FOXK2 Transcription Factor Suppresses ER alpha-positive Breast Cancer Cell Growth Through Down-Regulating the Stability of ER alpha via mechanism involving BRCA1/BARD1[J],SCIENTIFIC REPORTS,2015,5:8796 [31]Zhao, F.,Wang, M.,Li, S.,Bai, X.,Bi, H.,Liu, Y.,Ao, X.,Jia, Z.,Wu, H..DACH1 inhibits SNAI1-mediated epithelial-mesenchymal transition and represses breast carcinoma metastasis[J],ONCOGENESIS,2015,4(3):e143 [32]Cui, Xiaoneng,Zhao, Jianzhang,Lou, Zhangrong,Li, Shujing,Wu, Huijian,Han, Ke-li.Switching of the Triplet Excited State of Rhodamine/Naphthaleneimide Dyads: An Experimental and Theoretical Study[J],JOURNAL OF ORGANIC CHEMISTRY,2015,80(1):568-581 [33]张梅,王淼,伍会健.SUMO化修饰系统及其在肿瘤发展中的作用[J],中国细胞生物学学报,2015,37(10):1458-1464 [34]伍会健.GPS2的SUMO化修饰对乳腺癌发生发展的调控机理[A],2015 [35]赵建章,伍会健.Maximizing the Thiol-Activated Photodynamic and Fluorescence Imaging Functionalities of Theranostic Reagents by Modularization of the Bodipy-based Dyad Triplet Photosensitizers[J],J. Mater. Chem. B,2015,3(47) [36]伍会健.DEC1 regulates breast cancer cell proliferation by stabilizing cyclinE protein and delays the progression of cell cycle S phase[A],2015 [37]伍会健.核心节律蛋白CLOCK对乳腺癌发生发展的调控机理[A],2015 [38]Zhao, Jianzhang,Huang, Ling,Cui, Xiaoneng,Li, Shujing,Wu, Huijian.Maximizing the thiol-activated photodynamic and fluorescence imaging functionalities of theranostic reagents by modularization of Bodipy-based dyad triplet photosensitizers[J],JOURNAL OF MATERIALS CHEMISTRY B,2015,3(47):9194-9211 [39]王淼,李淑晶,伍会健.跨校区网络同步教学课程模式探索 细胞生物学课程改革[J],中国细胞生物学学报,2015,37(5):715-719 [40]陈敏,李淑晶,伍会健.泛素化与SUMO化对DNA损伤应答的调控作用简[J],生命的化学,2015,35(6):801-806 [41]杨杨杨,李淑晶,伍会健.F-box蛋白家族在肿瘤发生中的作用[J],中国细胞生物学学报,2015,37(8):1180-1186 [42]许兆伟,赵锋,伍会健.ERα辅调节因子在乳腺癌中的双重调控作用[J],中国细胞生物学学报,2014,10:1437-1442 [43]Bi, Hailian,Li, Shujing,Wang, Miao,Jia, Zhaojun,Chang, Alan K.,Pang, Pengsha,Wu, Huijian.SUMOylation of GPS2 protein regulates its transcription-suppressing function[J],MOLECULAR BIOLOGY OF THE CELL,2014,25(16):2499-2508 [44]Xiao, Liyun,Chang, Alan K.,Zang, Ming-Xi,Bi, Hailian,Li, Shujing,Wang, Miao,Xing, Xinrong,Wu, Huijian.Induction of the CLOCK Gene by E2-ER alpha Signaling Promotes the Proliferation of Breast Cancer Cells[J],PLOS ONE,2014,9(5):e95878 [45]伍会健.The relationship between the inflammatory response and cell adhesion[J],J Biomed Mater Res A,2014,14(1):1-11 [46]伍会健.Switching of the Triplet Excited State of Rhodamine/Naphthaleneimide Dyads: An Experimental and Theoretical Study[J],J. Org. Chem.,2014,80(1):568-581 [47]伍会健.Induction of the CLOCK Gene by E2-ERa Signaling Promotes the Proliferation of Breast Cancer Cells[J],PLoS One,2014,9(5):1-13 [48]王岛,Alan K Chang,伍会健.Hedgehog信号通路及其抑制剂在癌症中的研究进展[J],生命的化学,2014,34(1):98-103 [49]李珅,董杰,伍会健.抗体介导的慢性排斥反应中内皮细胞基因的变化及分子机制[J],中国细胞生物学学报,2014,36(1):123-127 [50]白晓彦,王淼,伍会健.一氧化氮相关的内皮功能障碍与高血压[J],生命的化学,2014,34(6):744-748 [51]胡高磊,刘英,伍会健.NEDD化修饰系统及其在肿瘤发展中的作用[J],中国生物化学与分子生物学报,2014,30(9):843-847 [52]许兆伟,赵锋,伍会健.ERalpha辅调节因子在乳腺癌中的双重调控作用[J],中国细胞生物学学报,2014,36(10):1437-1442 [53]伍会健.EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner[J],Cell. Mol. Life Sci.,2014,12(14):1-18 [54]陈艺轩,伍会健.雄激素受体翻译后修饰的研究进展[J],生理科学进展,2013,44(6):442-446 [55]徐飞鸿,毕海连,伍会健.昼夜节律与细胞周期[J],中国生物化学与分子生物学报,2013,11:1010-1016 [56]Li, S.,Wu, H.,Wang, M.,Ao, X.,Chang, A. K.,Yang, C.,Zhao, F.,Bi, H.,Liu, Y.,Xiao, L..CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-alpha[J],ONCOGENE,2013,32(41):4883-4891 [57]陈艺轩,伍会健.RNF111的SUMO修饰及其相关功能的研究[A],第四届泛环渤海生物化学与分子生物学会2013年学术交流会,2013,43-43 [58]贾兆君,伍会健.PPIL2对HDAC2的SUMO化修饰及调控[A],第四届泛环渤海生物化学与分子生物学会2013年学术交流会,2013,45-45 [59]徐飞鸿,伍会健.SUMO化修饰对DEC2相关功能影响的研究[A],第四届泛环渤海生物化学与分子生物学会2013年学术交流会,2013,47-47 [60]Li, Shujing,Ao, Xiang,Wu, Huijian.The role of circadian rhythm in breast cancer[J],CHINESE JOURNAL OF CANCER RESEARCH,2013,25(4):442-450 [61]Pan, Hongming,Niu, Wenquan,He, Lan,Wang, Bin,Cao, Jun,Zhao, Feng,Liu, Ying,Li, Shen,Wu, Huijian.Contributory Role of Five Common Polymorphisms of RAGE and APE1 Genes in Lung Cancer among Han Chinese[J],PLOS ONE,2013,8(7):e69018 [62]Wang, Miao,Zhao, Feng,Li, Shujing,Chang, Alan K.,Jia, Zhaojun,Chen, Yixuan,Xu, Feihong,Pan, Hongming,Wu, Huijian.AIB1 Cooperates with ER alpha to Promote Epithelial Mesenchymal Transition in Breast Cancer through SNAI1 Activation[J],PLOS ONE,2013,8(6):e65556 [63]Yang, Chunhua,Li, Shen,Wu, Huijian,Li, Shujing,Wang, Miao,Chang, Alan K.,Liu, Ying,Zhao, Feng,Xiao, Liyun,Han, Lin,Wang, Dao.PTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mechanism involving Fbw7 alpha[J],MOLECULAR CANCER,2013,12(1):21 [64]韩琳,伍会健.SENPs对肿瘤发展的分子调控机理[J],生理科学进展,2013,44(1):55-58 [65]肖利云,贾兆君,伍会健.昼夜节律钟调控代谢的研究进展[J],中国细胞生物学学报,2013,35(10):1533-1539 [66]徐飞鸿,毕海连,伍会健.时钟节律与细胞周期[J],中国生物化学与分子生物学报,2013,29(11):1010-1016 [67]伍会健.CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-α.[J],Oncogene.,2013,32(10):4883-4891 [68]伍会健.抗体介导的慢性排斥反应中内皮细胞基因的变化及分子机制[J],中国细胞生物学学报,2013,36(1):123-127 [69]贾兆君,伍会健.DSB修复过程中的组蛋白修饰作用[J],中国细胞生物学学报,2013,35(6):863-869 [70]伍会健.AIB1 Cooperates with ERa to Promote Epithelial Mesenchymal Transition in Breast Cancer through SNAI1 Activation.[J],Plos one.,2013,8(6):65556-65556 [71]Xing, Xinrong,Wu, Huijian,Bi, Hailian,Chang, Alan K.,Zang, Ming-Xi,Wang, Miao,Ao, Xiang,Li, Shen,Pan, Hongming,Guo, Qianping.SUMOylation of AhR modulates its activity and stability through inhibiting its ubiquitination[J],JOURNAL OF CELLULAR PHYSIOLOGY,2012,227(12):3812-3819 [72]Chang, Alan K.,Wu, Huijian.The role of AIB1 in breast cancer[J],ONCOLOGY LETTERS,2012,4(4):588-594 [73]杨春华,伍会健.PTEN以磷酸酶非依赖性形式调控AIB1转录活性[A],第三届泛环渤海(七省二市)生物化学与分子生物学会2012年学术交流会,2012,10-10 [74]韩琳,伍会健.SUMO修饰调控GPS2的转录抑制功能[A],第三届泛环渤海(七省二市)生物化学与分子生物学会2012年学术交流会,2012,12-12 [75]赵锋,韩琳,伍会健.雌激素受体α的翻译后修饰与乳腺癌[J],生理科学进展,2012,43(3):226-230 [76]Li, Shujing,Chang, Alan K.,Xiao, Liyun,Zhang, Yuanyuan,Wu, Huijian,Yang, Chunhua,Hong, Yongde,Bi, Hailian,Zhao, Feng,Liu, Ying,Ao, Xiang,Pang, Pengsha,Xing, Xinrong.The transcriptional activity of co-activator AIB1 is regulated by the SUMO E3 Ligase PIAS1[J],BIOLOGY OF THE CELL,2012,104(5):287-296 [77]张园园,肖利云,伍会健.转录辅调节因子在剪接过程中的作用[J],现代生物医学进展,2012,12(7):1374-1377 [78]潘洪明,赵锋,伍会健.泛素化和SUMO化对DEC1的拮抗调控作用[J],中国细胞生物学学报,2012,34(5):506-510 [79]伍会健.Steroid Receptor Co-activator-3 promotes breast cancer cell invasion and metastasis through SNAI1 expression[A],遗传学为人类造福——全球华人遗传学大会论文集,2012 [80]伍会健.DEC1 Up-regulates the Stability of Cyclin E by inhibiting its ubiquitination[A],遗传学为人类造福——全球华人遗传学大会论文集,2012 [81]伍会健.CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-α[J],Oncogene.,2012,19(10):1-9 [82]刘英,王岛,伍会健.JunD的结构功能特征及其在肿瘤发展中的作用[J],中国生物化学与分子生物学报,2012,28(7):603-608 [83]赵锋,韩琳,伍会健.雌激素受体alpha的翻译后修饰与乳腺癌[J],生理科学进展,2012,43(3):226-230 [84]Hong, Yongde,Wu, Huijian,Xing, Xinrong,Li, Shujing,Bi, Hailian,Yang, Chunhua,Zhao, Feng,Liu, Ying,Ao, Xiang,Chang, Alan K..SUMOylation of DEC1 Protein Regulates Its Transcriptional Activity and Enhances Its Stability[J],PLOS ONE,2011,6(8):e23046 [85]杨春华,刘英,伍会健.β-Trcp与肿瘤关系的研究[J],中国细胞生物学学报,2011,07:796-801 [86]毕海连,洪永德,伍会健.SUMO化修饰与DNA损伤修复[J],生理科学进展,2011,42(2):141-144 [87]杨春华,刘英,伍会健.beta-Trcp与肿瘤关系的研究[J],中国细胞生物学学报,2011,33(7):796-801 [88]毕海连,伍会健.细胞周期与时钟节律的相关性研究[A],2010,88-88 [89]刘英,伍会健.雄激素受体AR的研究进展[A],2010,85-85 [90]庞朋沙,伍会健.GPS2在基因转录调控中的机理研究[A],2010,86-86 [91]洪永德,伍会健.SUMO化修饰机制的研究进展[A],2010,87-87 [92]庞朋沙,伍会健.乳腺癌治疗靶标的研究进展[A],中国遗传学会北方遗传资源的保护与利用研讨会,2010,Vol.33:1 [93]刘英,伍会健.AhR的信号通路及功能研究[A],中国遗传学会北方遗传资源的保护与利用研讨会,2010,Vol.33:1 [94]庞朋沙,过倩萍,伍会健.细胞内AhR信号转导通路的机制研究[J],现代生物医学进展,2010,10(13):2567-2570 [95]李淑晶,毕海连,伍会健.泛素连接酶APC/C和SCF复合物与肿瘤的关系[J],北京大学学报(医学版),2010,42(2):243-封3 [96]伍会健.核受体ERa通路的研究进展[A],东北三省及内蒙古生物化学与分子生物学会,2010 [97]伍会健.时钟蛋白DEC1的研究进展[A],东北三省及内蒙古生物化学与分子生物学会,2010 [98]敖翔,李淑晶,伍会健.周期节律与肿瘤关系的分子机理[J],中国生物化学与分子生物学报,2010,26(11):998-1002 [99]洪永德,罗福文,伍会健.SUMO与乳腺癌[J],现代生物医学进展,2009,9(20):3976-3979 [100]肖利云,伍会健.PTEN对雌激素受体转录活性的调节[A],东北三省及内蒙古地区遗传学研究进展学术研讨会,2009,Vol.32:1 [101]洪永德,伍会健.转录辅激活因子AIB1调控前体-mRNA剪接的研究[A],东北三省及内蒙古地区遗传学研究进展学术研讨会,2009,Vol.32:1 [102]杨春华,伍会健.节律蛋白在乳腺癌中作用机制的研究[A],东北三省及内蒙古地区遗传学研究进展学术研讨会,2009,Vol.32:1 [103]杨春华,洪永德,伍会健.SUMO对NF-κB信号通路的调控作用[J],生理科学进展,2009,40(2):154-157 [104]刘文栋,伍会健.PIAS蛋白家族的功能[J],现代生物医学进展,2009,9(2):397-400 [105]伍会健.Serum Inhibitor for the Trimeresurus flavoviridis Venom Phospholipase A2: Purification, Characterization and cDNA Cloning[J],生理通讯,2009,28(2):76-76 [106]过倩萍,邢欣荣,伍会健.蛋白质修饰对Wnt信号通路的调控[J],中国生物化学与分子生物学报,2009,25(2):110-115 [107]刘文栋,庞朋沙,伍会健.蛋白质多聚SUMO化修饰及其功能[J],中国生物化学与分子生物学报,2009,25(11):977-982 [108]杨春华,洪永德,伍会健.SUMO对NF-kappaB信号通路的调控作用[J],生理科学进展,2009,40(2):154-157 [109]伍会健.Snake Serum Albumin as an Inhibitor of Venom Zinc Proteases:[J],生理通讯,2009,28(2):77-77 [110]程智逵,过倩萍,伍会健.组蛋白精氨酸甲基化修饰对基因转录的调控[J],生物化学与生物物理进展,2008,35(11):1225-1230 [111]邢欣荣,刘宇博,程智逵,伍会健.组蛋白修饰酶对基因转录的调控[J],生理科学进展,2008,39(4):314-318 [112]李淑晶,刘文栋,伍会健.二恶英对雌激素受体的干扰作用[J],生命科学,2008,20(5):764-767 [113]洪永德,肖利云,伍会健.转录辅激活因子SRC-3调控前体-mRNA剪接的相关研究[A],东北三省生物化学与分子生物学学会2008年学术交流会,2008,2 [114]杨春华,李淑晶,伍会健.PTEN对ERα转录活性的调节[A],东北三省生物化学与分子生物学学会2008年学术交流会,2008,1 [115]刘文栋,程智逵,伍会健.PIAS-1在炎症相关的NF-κB信号通路中的功能研究[A],东北三省生物化学与分子生物学学会2008年学术交流会,2008,1 [116]姚长敏,邢欣荣,伍会健.环境内分泌干扰物的致癌机理研究[A],东北三省生物化学与分子生物学学会2008年学术交流会,2008,1 [117]过倩萍,伍会健.MAPKAPK-2在乳腺癌中的机制研究[A],东北三省生物化学与分子生物学学会2008年学术交流会,2008,1 [118]肖利云,杨春华,邢欣荣,伍会健.SENP1与前列腺癌[J],中国生物化学与分子生物学报,2008,24(3):209-213 [119]伍会健.转录辅激活因子SRC-3调控前体mRNA剪接的相关研究[A],辽宁省遗传学会,2008 [120]伍会健.CARM-1对CLOCK甲基化的功能研究[A],辽宁省遗传学会,2008 [121]伍会健.SUMO化修饰对CARM-1转录活性的调节[A],辽宁省遗传学会,2008 [122]李淑晶,程智逵,伍会健.SUMO在转录中的抑制作用[J],中国生物化学与分子生物学报,2007,23(7):525-530 相关热点
最新收录
- Sien小慧君 05-22
- 罗杰叔叔(Uncle Roger) 05-22
- 悉尼妹(Sydney Sweeney) 05-22
- 玩具砖家 05-19
- 行走的大大大羊腿 05-19
- 梦飞大大 05-19
- 晏安anan 05-19
- 恰饭DZZ 05-19
- 爱玩具的大成 05-19
- 爱拍照的玉老师 05-19