个人简历

2011年2月获得英国爱丁堡大学博士学位，其间成功合成了具有保护及促进神经细胞生长显著生物活性的倍半萜类天然产物Merrilactone A 和Anislactone A&B，其中Anislactone A&B是国际首次全合成。同年获得默克研究基金资助，加入美国顶级生物医学化学研究所The Scripps Research Institute（斯克利普斯研究所）天然产物全合成大师K. C. Nicolaou教授（美国国家科学院和美国艺术与科学院院士）课题组从事博士后研究，成功合成了Myceliothermophins、Otermycin和Dioporthichalasin等具有抗肿瘤活性的聚酮类天然产物，此研究可望为创新抗癌药物研发提供先导化合物，同时参与了广谱抗菌素CJ-16，264的国际首次全合成。
长期致力于有机合成方法学和复杂天然产物的全合成研究，迄今为止在Angew. Chem. Int. Ed.、J. Am. Chem. Soc.、Chemistry - A European Journal等国际知名杂志上共发表学术论文十多篇。其中，1篇被Angew. Chem. Int. Ed.选为热点论文HOT PAPER，2 篇被Thieme旗下著名评论期刊Synfacts选为亮点重点推介，他引总数400于次，其中单篇他引超过50次的有3篇。为Strategies and Tactics in Organic Synthesis丛书（Elsevier，2013）撰写章节一篇，其研究工作多次被化学领域顶级杂志期刊引用并专题评述，研究成果得到了相关领域学术界的关注并产生了一定的影响力。
所获奖励：
1. Overseas Research Students Awards Scheme (ORSAS), UK, 2007-2010
2. Engineering and Physical Sciences Research’s fellowship, UK, 2007-2010
3. Merck Research Fellowship Awards, US, 2011-2012
教育经历

2007.9 - 2011.2 爱丁堡大学 化学类其他专业 博士

研究领域

1.金属有机手性催化剂的不对称催化性能研究；
2.基于过渡金属催化体系的新型光化学反应研究；
3.功能化MOFs的构筑及其在催化领域中的应用。""

近期论文

1. K. C. Nicolaou,* Akshay A. Shah, Henry Korman, Tabrez Khan, Lei Shi,Wisuttaya Worawalai,and Emmanuel A. Theodorakis Total Synthesis and Structural Revision of Antibiotic CJ-16,264. Angewandte Chemie, International Edition. 2015. 54，9203-9208
2. Nicolaou, K. C.*; Lei Shi, Min Lu, Manas R. Pattanayak, Heraklidia A. Ioannidou,Manjunath Lamani, Total synthesis of Myceliothermophins C and D. Angewandte Chemie, International Edition. 2014. 49，10970-10974
3. Nicolaou, K. C.*; Yu, Ruocheng; Shi, Lei; Cai, Quan; Lu, Min; Heretsch, Philipp, A General Synthetic Approach to Functionalized Dihydrooxepines, Organic Letters, 2013, 15(8), 1994-1997.
4. Micheal Greaney*, Lei Shi, Naim, Total synthesis of (±) Anislactone A and (±) Merrilactone A, Strategies and Tactics in Organic Synthesis, 2013, Vol 9, 105-147.
5. Xuefeng Jiang, Lei Shi, Hui Liu, Akbar H. Khan and Jason S. Chen, Gas extrusion in natural products total synthesis. Org. Biomol. Chem., 2012, 10, 8383-8392 (review).
6. Lei Shi, Karsten Meyer and Michael F. Greaney*, Synthesis of (±) Merrilactone A and (±) Anislactone A. Angewandte Chemie, International Edition. 2010, 49, 9250-9253.
7. Lei Shi, Xingwang Wang, Christian A. Sandoval, Zheng Wang, and Kuiling Ding*, Development of Continuous Flow System for Asymmetric Hydrogenation Using Self-Supported Chiral Catalysts, Chemistry - A European Journal. 2009,15, 9855-9867 (full paper).
8. DING Kuiling*, Wang Zheng, SHI Lei, Self-Supported Chiral Catalysts for Heterogeneous Enantioselective Reactions. Pure Applied Chemistry, 2007, 79, 1531-1540 (review).
9. Lei shi, Xingwang Wang, Mingxing Li, Zhanting Li, Kuiling Ding*, Engineering polymeric chiral catalyst using hydrogen bonding and metal-to-ligand coordination interaction, Angewandte Chemie, International Edition. 2006, 45, 4108-4112.
10. Xingwang Wang, Lei Shi, Mingxing Li, Kuiling Ding*, Heterogenization of Shibasaki's Binol/La Catalyst for Enantioselective Epoxidation of α,β-Unsaturated Ketones with Multitopic Binol Ligands: The Impact of Bridging Spacers, Angewandte Chemie, International Edition. 2005, 44, 6362-6366.
11. Yuxue Liang, Qing Jing, Xin Li, Lei Shi, Kuiling Ding*, Programmed Assembly of Two Different Ligands with Metallic Ions: Generation of Self-Supported Noyori- type Catalysts for Heterogeneous Asymmetric Hydrogenation of Ketones, Journal of the American Chemical Society 2005, 127, 7694-7695.
12. Shi Lei, Wang Zheng, Wang Xingwang, Li Mingxing; Ding Kuiling*, A new method for chiral catalyst immobilization: Self-supporting strategy Chinese Journal of Organic Chemistry, 2006, 26, 1444-1456 (review).
13. LI Ming-Xing*, DAI Hui, SHAO Min, SHI Lei, LIN Kun-Hua, CHENG Zhi-Xuan, WENG Lin-Hong，Synthesis, Crystal Structures, Thermal Analysis and Magnetic Property of Mono- and Binuclear 1,1-Cyclobutanedicarbox-late Copper Complexes, Chinese Journal of Chemistry. 2006, 487.