个人简历

教育经历
2005.3 2010.6 大连理工大学 生物化工 博士
2000.9 2003.6 大连理工大学 化学工程 硕士
1996.9 2000.7 大连理工大学 高分子化 学士
工作经历
2014.12 至今 大连理工大学 副教授
2006.5 2014.12 大连理工大学 讲师
2003.7 2006.5 大连理工大学 助教
团队成员
Research Group
生物转化与分离
主要研究方向：生物质能源和生物基化学品、海洋生物资源高效利用、天然产物生物转化、生物过程与系统工程。课题组共有1名教授，4位副教授。先后完成国家自然科学基金、国家重点科技攻关项目、国家863项目、973子课题、科技部“重大新药创制”专项课题、教育部新世纪优秀人才支持计划和企业委托工程技术开发等30余项课题。
专利
一种混菌发酵甘油生产1,3-丙二醇的方法
一种混菌发酵甘油生产1,3-丙二醇的方法
一种二元醇与有机酸联产和分离的方法
Method for salting-out extraction of acetone and butanol from a fermentation broth
一种二元醇和有机酸联产和分离方法
一种偶联生产生物柴油和1,3-丙二醇的方法
著作成果
生物化学
多级生物加工系统优化原理与技术，第五章 1, 3-丙二醇生物合成过程及其优化与控制
Bioprocessing of renewable resources to commodity bioproducts
非线性发酵动力系统
化工过程分析与综合
生物化学
科研项目
海参加工液中有效成分的盐析萃取技术与关键装备, 省、市、自治区科技项目, 2012/01/01, 完成
生物制造分离过程技术与装备, 国家“863”项目 , 2012/01/01, 完成
1,3-丙二醇与琥珀酸联产代谢调控机制研究, 国务院其他部门, 2012/01/01-2017/03/20, 完成
dha调控子的基因调控与甘油代谢振荡机制研究, 国家自然科学基金项目, 2013/09/25-2016/12/31, 完成
基于生长和代谢特征的底物流加发酵生产1,3-丙二醇的控制方法, 国家自然科学基金项目, 2018/07/20-2030/03/31, 进行
海洋微生物菌群的特性及其工业应用, 其他课题, 2016/11/28, 进行
科研奖励
辽宁省科学技术奖励
辽宁省技术发明二等奖
其他奖励
2017中国化工学会年会优秀论文奖 （2017年）
校教学质量优良奖 （2017年）
大连理工大学2012年度考核优秀 （2013年）
化工与环境生命学部2012年度优秀教师 （2013年）
化工与环境生命学部青年教师讲课竞赛一等奖 （2011年）
大连理工大学青年教师讲课竞赛二等奖 （2010年）

研究领域

生物基化学品转化及代谢调控
多尺度生物系统网络
大宗发酵产品分离提取""

近期论文

[1]Sun, Yaqin,Zhang, Xingxing,Zheng, Yafeng,Yan, Ling,Xiu, Zhilong.Sugaring-out extraction combining crystallization for recovery of succinic acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,209:972-983
[2]Sun, Yaqin,Zheng, Yafeng,Wang, Xiaoli,Zhou, Jinjie,Xiu, Zhilong.Fermentation performance and mechanism of a novel microbial consortium DUT08 for 1,3-propandiol production from biodiesel-derived crude glycerol under non-strictly anaerobic conditions[J],PROCESS BIOCHEMISTRY,2019,83:27-34
[3]Sun, Yaqin,Xu, Zhenzhen,Zheng, Yafeng,Zhou, Jinjie,Xiu, Zhilong.Efficient production of lactic acid from sugarcane molasses by a newly microbial consortium CEE-DL15[J],PROCESS BIOCHEMISTRY,2019,81:132-138
[4]Li, Zhen,Yan, Ling,Zhou, Jinjie,Wang, Xiaoli,Sun, Yaqin,Xiu, Zhi-Long.Two-step salting-out extraction of 1,3-propanediol, butyric acid and acetic acid from fermentation broths[J],SEPARATION AND PURIFICATION TECHNOLOGY,2019,209:246-253
[5]Sun, Yaqin,Zhang, Shuangshuang,Zhang, Xingxing,Zheng, Yafeng,Xiu, Zhilong.Ionic liquid-based sugaring-out and salting-out extraction of succinic acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,204:133-140
[6]Zhou, Jin-Jie,Shen, Jun-Tao,Wang, Xiao-Li,Sun, Ya-Qin,Xiu, Zhi-Long.Stability and oscillatory behavior of microbial consortium in continuous conversion of crude glycerol to 1,3-propanediol[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(19):8291-8305
[7]Sun, Ya-Qin,Shen, Jun-Tao,Yan, Ling,Zhou, Jin-Jie,Jiang, Li-Li,Chen, Yang,Yuan, Jin-Long,Feng, Enmin,Xiu, Zhi-Long.Advances in bioconversion of glycerol to 1,3-propanediol: Prospects and challenges[J],PROCESS BIOCHEMISTRY,2018,71:134-146
[8]Yan, Ling,Sun, Ya-Qin,Wang, Xu-Dong,Fu, Hong-Xin,Mu, Ying,Xiu, Zhi-Long.Partition behavior of monocarboxylic acids in salting-out extraction systems of monohydric alcohols and dipotassium phosphate[J],SEPARATION AND PURIFICATION TECHNOLOGY,2018,199:351-358
[9]鄢凌,傅宏鑫,王旭东,孙亚琴,戴建英,修志龙.生物基有机酸提取分离技术研究进展[J],过程工程学报,2018,18(1):1-10
[10]Jiang, Lili,Dai, Jianying,Sun, Yaqin,Xiu, Zhilong.The effects of ionic liquid 1-ethyl-3-methylimidazolium trifluoromethanesulfonate on the production of 1,3-propanediol from crude glycerol by microbial consortium.[J],Bioprocess and biosystems engineering,2018,41(8):1079-1088
[11]Zhou, Jin-Jie,Shen, Jun-Tao,Jiang, Li-Li,Sun, Ya-Qin,Mu, Ying,Xiu, Zhi-Long.Selection and characterization of an anaerobic microbial consortium with high adaptation to crude glycerol for 1,3-propanediol production[J],APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2017,101(15):5985-5996
[12]Fu, Hongxin,Wang, Xudong,Sun, Yaqin,Yan, Ling,Shen, Juntao,Wang, Jufang,Yang, Shang-Tian,Xiu, Zhilong.Effects of salting-out and salting-out extraction on the separation of butyric acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2017,180:44-50
[13]Jiang, LiLi,Liu, HuiFang,Mu, Ying,Sun, YaQin,Xiu, ZhiLong.High tolerance to glycerol and high production of 1,3-propanediol in batch fermentations by microbial consortium from marine sludge[J],ENGINEERING IN LIFE SCIENCES,2017,17(6):635-644
[14]王路,刘涛,陈洋,孙亚琴,修志龙.基于傅里叶变换近红外光谱实时分析1,3-丙二醇发酵过程生物量的在线监测方法[J],生物工程学报,2017,33(1):68-78
[15]周瑾洁,王旭东,孙亚琴,修志龙.生物基化学品的微生物电合成研究进展[J],化工进展,2016,35(10):3005-3015
[16]Shen, Juntao,Zhou, Jinjie,Fu, Hongxin,Mu, Ying,Sun, Yaqin,Xu, Yongping,Xiu, Zhilong.A Klebsiella pneumoniae bacteriophage and its effect on 1,3-propanediol fermentation[J],PROCESS BIOCHEMISTRY,2016,51(10):1323-1330
[17]姜莉莉,周瑾洁,王旭东,孙亚琴,修志龙.微生物菌群发酵生产化学品的研究进展[J],生物工程学报,2016,32(11):1496-1506
[18]Yan, Ling,Sun, Ya-Qin,Xiu, Zhi-Long.Sugaring-out extraction coupled with fermentation of lactic acid[J],SEPARATION AND PURIFICATION TECHNOLOGY,2016,161:152-158
[19]牟英,孙亚琴,徐永平,修志龙.A novel Klebsiella pneumoniae bacteriophage and its effect on 1, 3-propanediol fermentation[J],Process Biochemistry,2016,51(7):1323-1330
[20]孙亚琴.Conversion of glucose and gluconate to ethanol in mineral salts medium using recombinant Escherichia coli strains[J],Fermentation Technology,2016,5(3):1-5
[21]Fu, Hongxin,Dai, Jianying,Sun, Yaqin,Zhang, Daijia,Xiu, Zhilong.Partition behavior of hydrophilic diols in an ethanol/ammonium sulfate salting-out extraction system[J],ENGINEERING IN LIFE SCIENCES,2015,15(8):797-803
[22]Chen, Deling,Yang, Xiangchun,Cao, Wenjing,Guo, Yuxi,Sun, Yaqin,Xiu, Zhilong.Three-liquid-phase salting-out extraction of effective components from waste liquor of processing sea cucumber[J],FOOD AND BIOPRODUCTS PROCESSING,2015,96:99-105
[23]修志龙,戴建英,孙亚琴.盐/糖析萃取技术在生物基化学品分离中的应用[A],2015年中国化工学会年会,2015,1
[24]Fu, Hongxin,Sun, Yaqin,Teng, Hu,Zhang, Daijia,Xiu, Zhilong.Salting-out extraction of carboxylic acids[J],SEPARATION AND PURIFICATION TECHNOLOGY,2015,139:36-42
[25]杨向春,陈德玲,秦超,孙亚琴,张代佳,修志龙.海参加工液的高值化综合利用[A],全国第九届海洋生物技术与创新药物学术会议,2014,1
[26]Sun, Yaqin,Yan, Ling,Fu, Hongxin,Xiu, Zhilong.Salting-out extraction and crystallization of succinic acid from fermentation broths[J],PROCESS BIOCHEMISTRY,2014,49(3):506-511
[27]Dai, Jian-Ying,Sun, Ya-Qin,Xiu, Zhi-Long.Separation of bio- based chemicals from fermentation broths by salting- out extraction[J],ENGINEERING IN LIFE SCIENCES,2014,14(2):108-117
[28]Li, Zhi-Gang,Sun, Ya-Qin,Zheng, Wei-Long,Teng, Hu,Xiu, Zhi-Long.A novel and environment-friendly bioprocess of 1,3-propanediol fermentation integrated with aqueous two-phase extraction by ethanol/sodium carbonate system[J],BIOCHEMICAL ENGINEERING JOURNAL,2013,80:68-75
[29]戴建英,刘春娇,孙亚琴,修志龙.盐析萃取生物基化学品的研究进展[J],生物工程学报,2013,29(10):1441-1449
[30]南南,曹放,沈俊涛,绳傲楠,孙亚琴,牟英,修志龙.一株产1,3-丙二醇的克雷伯氏菌的噬菌体生物学特性[J],微生物学报,2013,53(9):943-949
[31]Sun, Yaqin,Yan, Ling,Fu, Hongxin,Xiu, Zhilong.Selection and optimization of a salting-out extraction system for recovery of biobutanol from fermentation broth[J],ENGINEERING IN LIFE SCIENCES,2013,13(5):464-471
[32]Song, Zhiyuan,Sun, Yaqin,Wei, Bochao,Xiu, Zhilong.Two-step salting-out extraction of 1,3-propanediol and lactic acid from the fermentation broth of Klebsiella pneumoniae on biodiesel-derived crude glycerol[J],ENGINEERING IN LIFE SCIENCES,2013,13(5):487-495
[33]Fu, Hongxin,Sun, Yaqin,Xiu, Zhilong.Continuous countercurrent salting-out extraction of 1,3-propanediol from fermentation broth in a packed column[J],PROCESS BIOCHEMISTRY,2013,48(9):1381-1386
[34]陈德玲,杨向春,曹文静,郭禹熙,孙亚琴,修志龙.海参加工液中有效成分的盐析萃取[J],过程工程学报,2013,13(2):297-301
[35]Sun Yaqin,Ye Jianxiong,Mu Xiaojia,Teng Hu,Feng Enmin,Zeng Anping,Xiu Zhilong.Nonlinear Mathematical Simulation and Analysis of Dha Regulon for Glycerol Metabolism in Klebsiella pneumoniae[J],CHINESE JOURNAL OF CHEMICAL ENGINEERING,2012,20(5):958-970
[36]魏搏超,宋志远,孙亚琴,修志龙.发酵液中乳酸的盐析萃取[J],过程工程学报,2012,12(1):44-48
[37]姜芹,孙亚琴,滕虎,修志龙,刘春朝.纤维素燃料乙醇技术经济分析[J],过程工程学报,2012,12(1):97-104
[38]Sun, Yaqin,Teng, Hu,Xiu, Zhilong.Nonlinear Enzyme-catalytic Kinetics of Glycerol Dissimilation to 1,3-Propanediol by Klebsiella pneumoniae[J],JOURNAL OF BIOTECHNOLOGY,2010,150:S527-S527
[39]修志龙,郭峰,梁志霞,滕虎,孙亚琴.第二代生物柴油及其生物炼制关键技术[A],中国化工学会2010年年会暨第二届石油补充与替代能源开发利用技术论坛,2010,58-63
[40]修志龙,郭峰,梁志霞,滕虎,孙亚琴.第二代生物柴油及其生物炼制关键技术[J],化工进展,2010,29(z1):58-63
[41]Sun, Li-Hui,Song, Zhi-Yuan,Sun, Ya-Qin,Xiu, Zhi-Long.Dynamic behavior of glycerol-glucose co-fermentation for 1,3-propanediol production by Klebsiella pneumoniae DSM 2026 under micro-aerobic conditions[J],WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,2010,26(8):1401-1407
[42]戴建英,孙亚琴,孙丽慧,李丹,董悦生,修志龙.生物基化学品2,3-丁二醇的研究进展[J],过程工程学报,2010,10(1):200-208
[43]Sun, Yaqin,Mu, Xiaojia,Li, Zheng,Teng, Hu,Xiu, ZhiLong.Robustness and nonlinear dynamic analysis for trp operon and optimization of tryptophan production[A],4th International Conference on Bioinformatics and BiomedicalEngineering (iCBBE),2010
[44]牟晓佳,滕虎,孙亚琴,修志龙.甘油发酵生产1,3-丙二醇工艺的技术经济性分析[J],过程工程学报,2009,9(5):947-952
[45]Ye, J.,Feng, E.,Wang, L.,Xiu, Z.,Sun, Y..Modeling and robustness analysis of biochemical networks of glycerol metabolism by Klebsiella pneumoniae[J],Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering,2009,4 LNICST(PART 1):446-457
[46]刘国兴,王元好,孙丽慧,戴建英,孙亚琴,董悦生,修志龙.盾叶薯蓣糖化液发酵生产2,3-丁二醇[J],过程工程学报,2009,9(1):95-100
[47]张江红,江波,李志刚,孙丽慧,孙亚琴,戴建英,修志龙.2,3-丁二醇发酵液的双水相萃取[J],过程工程学报,2008,8(5):897-900
[48]Sun, Lihui,Song, Zhiyuan,Sun, Yaqin,Xiu, Zhilong.Dynamic behavior of glycerol-glucose co-fermentation for 1,3-propanediol production by Klebsiella pneumoniae under microaerobic conditions[J],JOURNAL OF BIOTECHNOLOGY,2008,136:S411-S411
[49]Sun, Yaqin,Mu, Xiaojia,Li, Zheng,Xiu, ZhiLong.Robustness and nonlinear dynamic analysis for Escherichia coli trp operon by an integrated model considering genetic regulation and product excretion[J],JOURNAL OF BIOTECHNOLOGY,2008,136:S517-S517
[50]孙亚琴,牟晓佳,滕虎,修志龙.甘油生物歧化过程基因调控杂合非线性模型的建立与分析[A],第五届全国化学工程与生物化工年会,2008,48-49
[51]Zhang, Qingrui,Teng, Hu,Sun, Yaqin,Xiu, Zhilong,Zeng, Anping.Metabolic flux and robustness analysis of glycerol metabolism in Klebsiella pneumoniae[J],BIOPROCESS AND BIOSYSTEMS ENGINEERING,2008,31(2):127-135
[52]Sun, Ya Qin,Qi, Wen Tao,Teng, Hu,Xiu, Zhi Long,Zeng, An Ping.Mathematical modeling of glycerol fermentation by Klebsiella pneumoniae: Concerning enzyme-catalytic reductive pathway and transport of glycerol and 1,3-propanediol across cell membrane[J],BIOCHEMICAL ENGINEERING JOURNAL,2008,38(1):22-32
[53]修志龙,李晓晖,李世荣,孙亚琴.谈研究论文写作[J],大连理工大学第十四次本科教育教学研讨会论文集,2008,14(1):123-131
[54]刘海军,张代佳,徐友海,孙亚琴,吕继萍,牟英,修志龙.微生物发酵法中试生产1,3-丙二醇[J],现代化工,2007,27(2):56-58,60
[55]高素军,张代佳,孙亚琴,修志龙.Separation of 1,3-propanediol from glycerol-based fermentations of Klebsiella pneumoniae by alcohol precipitation and dilution crystallization[J],Front. Chem. Eng,2007,1(2):1-6
[56]Xiu, Zhi-Long,Chen, Xi,Sun, Ya-Qin,Zhang, Dai-Jia.Stoichiometric analysis and experimental investigation of glycerol-glucose co-fermentation in Klebsiella pneumoniae under microaerobic conditions[J],BIOCHEMICAL ENGINEERING JOURNAL,2007,33(1):42-52
[57]张青瑞,滕虎,孙亚琴,修志龙.Metabolic Flux Analysis of Bioconversion of Glycerol into 1,3-Propandiol by Klebsiella pneumoniae[A],Bioinformatics and Biomedical Engineering, ICBBE 2007,2007,1269-1272
[58]马成伟,孙亚琴,修志龙.葡萄糖和木糖双底物生物转化生产2,3-丁二醇和氢气的代谢计量分析[J],生物加工过程,2006,4(3):44-50
[59]马成伟,杜彤,孙亚琴,修志龙.生物转化法生产2,3-丁二醇的研究[J],精细与专用化学品,2006,14(15):15-18
[60]张代佳,高素军,孙亚琴,修志龙.超滤-醇沉法从发酵液中提取1,3-丙二醇[J],过程工程学报,2006,6(3):454-457
[61]魏关锋,孙亚琴,贺高红,姚平经,罗行,罗采尔.用改进的遗传算法进行多流股换热器网络综合[J],大连理工大学学报,2004,44(2):218-223
[62]Ling Yan,Yaqin Sun.Sugaring-out extraction coupled with fermentation of lactic acid[J],Separation and Purification Technology,2016,161:152-158