李晓宇
近期热点
资料介绍
个人简历
个人简介Personal Profile李晓宇,女,1980年2月生。1998.9~2002.7大连理工大学化工学院高分子化学专业学习,获学士学位; 2002.9~2008.3大连理工大学环境与生命学院生物科学与工程系学习,获博士学位;2008.3~2015.12,大连理工大学生命科学与技术学院,讲师;2016.1~至今,大连理工大学生命科学与技术学院,副教授;2011.3~2012.3 美国康奈尔大学访问学者。现任辽宁省食品安全源头保障创新团队岗位专家。长期从事饲用抗生素替代品及养殖业废弃物无害化处理与资源化利用研究。近5年来,申请人作为负责人承担国家“十三五”重点研发计划1项、国家自然科学基金青年基金1项、中国博士后科学基金1项、辽宁省农业领域青年科技创新人才项目1项、科技援疆项目1项,作为项目骨干参与国家海洋公益项目1项、国家“十二五”农村领域国家科技计划(863计划)1项、国家自然科学基金重大国际合作项目1项、国家自然科学基金面上项目2项,大连市科技计划项目1项,发表学术论文40余篇(SCI英文论文26篇,其中第一作者8篇,通讯作者3篇),申请国家发明专利12项,6项已获授权。先后获辽宁省科技进步二等奖2项,大连市科技进步一等奖1项。 教育经历1995.9 1998.7 大连经济技术开发区第一中学 理科2002.9 2008.3 大连理工大学 生物化工 博士1998.9 2002.7 大连理工大学 高分子化工 学士工作经历2008.3 至今 大连理工大学专利 一类含2-氨基嘧啶的萘酰亚胺化合物,其制备方法及应用 一种具有抗虫功能的生物有机肥及其制备方法 防治刺参腐皮综合症的噬菌体及其应用 金花茶叶提取物的应用、美白护肤组合物及其制备方法 复合微生物海藻肥的制备方法 抗黄海希瓦氏菌卵黄抗体及其制备方法 科研项目 适于死畜禽及屠宰废弃物处理多功能微生物制剂产品研制, 国家科技部 , 2016/01/01, 进行 特异性卵黄抗体防治口臭的研究, 国务院其他部门, 2010/01/01, 进行 用于防治奶牛乳腺炎的特异性卵黄抗体中试与示范, 国际合作项目, 2014/01/01, 进行 刺参、海水鱼重要病原特异性卵黄抗体产品研发, 省、市、自治区科技项目, 2014/11/01, 进行 卵黄抗体(IgY)对早期断奶仔猪免疫应激的调节作用研究, 国家自然科学基金项目, 2010/09/25-2013/12/31, 完成 INFEWS:U.S.-China:乙醇厂生产动物饲料--完全转化玉米和农业副产物支持生物燃料和饲料生产, 国家自然科学基金项目, 2018/08/09, 进行科研奖励 大连市科技进步一等奖 辽宁省科技进步二等奖 辽宁省科学技术研究成果奖 八师石河子市科技进步二等奖 大连市科技进步一等奖 辽宁省科技进步二等奖 其他奖励 2013年度优秀硕士学位论文指导教师 (2016年) 2013年度校优秀班主任 (2014年) 获2012年度“考核优秀”荣誉称号 (2013年) 2010年校教学质量优良奖 (2011年) 2009年学院青年教师讲课竞赛 (2009年)研究领域
养殖废弃物及病死畜禽尸体无害化处理与资源化利用卵黄免疫球蛋白(IgY)替代抗生素的研究裂解性噬菌体技术控制动物细菌性疾病微切变-助剂互作技术高效利用天然活性物质的研发""近期论文
[1]Li Jingbo,Wang Xitao,Cong Cong,Wan Leibing,Xu Yongping,Li Xiaoyu,Hou Fuqin,Wu Yanyan,Wang Lili.Inoculation of cattle manure with microbial agents increases efficiency and promotes maturity in composting[J],3 Biotech,2020,10(3):128 [2]Wan, Leibing,Wang, Xitao,Cong, Cong,Li, Jingbo,Xu, Yongping,Li, Xiaoyu,Hou, Fuqin,Wu, Yanyan,Wang, Lili.Effect of inoculating microorganisms in chicken manure composting with maize straw[J],BIORESOURCE TECHNOLOGY,2020,301:122730 [3]王丽丽,李晓宇,徐永平.In vitro non-specific immunostimulatory effect of alginate oligosaccarides with different molecular weights and compositions on sea cucumber (Apostichopus japonicus) coelomocytes[J],Aquaculture,2014,434(11):434-441 [4]Yuan Yuyu,Qu Kunli,Tan Demeng,Li Xiaoyu,Wang Lili,Cong Cong,Xiu Zhilong,Xu Yongping.Isolation and characterization of a bacteriophage and its potential to disrupt multi-drug resistant Pseudomonas aeruginosa biofilms[J],Microbial pathogenesis,2019,128:329-336 [5]Bao Pengyun,Li Xiaoyu,Xu Yongping.An Evaluation on the Ratio of Plant to Animal Protein in the Diet of Juvenile Sea Cucumber (Apostichopus japonicus): Growth, Nutrient Digestibility and Nonspecific Immunity[J],JOURNAL OF OCEAN UNIVERSITY OF CHINA,2018,17(6):1479-1486 [6]Wang, Xiaoli,Xu, Fanxing,Zhang, Henghui,Peng, Liang,Zhen, Yuhong,Wang, Lili,Xu, Yongping,He, Dongye,Li, Xiaoyu.Orthogonal test design for optimization of the extraction of essential oil from Asarum heterotropoides var. Mandshuricum and evaluation of its antibacterial activity against periodontal pathogens[J],3 BIOTECH,2018,8(11):473 [7]包鹏云,丛玉婷,李晓宇,徐永平.动植物蛋白比恒定的饲料中发酵豆粕对刺参生产性能、消化酶和非特异性免疫的影响[J],饲料工业,2018,39(8):42-47 [8]He, Dongye,Li, Xiaoyu,Sai, Xuan,Wang, Lili,Li, Shuying,Xu, Yongping.Camellia nitidissima CW Chi: a review of botany, chemistry, and pharmacology[J],PHYTOCHEMISTRY REVIEWS,2018,17(2,SI):327-349 [9]于小娟,徐永平,王丽丽,张美霞,李晓宇.CpG-ODN作为动物疫苗佐剂的研究进展[J],黑龙江畜牧兽医,2018,05:88-92 [10]He, Dongye,Sai, Xuan,Wang, Ning,Li, Xiaoyu,Wang, Lili,Xu, Yongping.Camellia euphlebia exerts its antidepressant-like effect via modulation of the hypothalamic-pituitary-adrenal axis and brain monoaminergic systems[J],METABOLIC BRAIN DISEASE,2018,33(1):301-312 [11]Zhang, Henghui,Xu, Yongping,Zhang, Zhijun,You, Jiansong,Yang, Yanyong,Li, Xiaoyu.Protective immunity of a Multivalent Vaccine Candidate against piglet diarrhea caused by enterotoxigenic Escherichia coli (ETEC) in a pig model[J],VACCINE,2018,36(5):723-728 [12]李晓宇,徐永平.An evaluation on the ratio of plant to animal protein in the diet of juvenile sea cucumber (Apostichopus japomicus): growth, nutrient digestibility and nonspecific immunity[J],Journal of Ocean University of China,2018,17(6):1479-1486 [13]王丽丽,李晓宇,徐永平.金黄色葡萄球菌致奶牛乳腺炎的噬菌体防控研究[A],2018 [14]徐永平,王丽丽,李晓宇.Complete genome sequence and analysis of novel lytic Vibrio parahaemolyticus bacteriophage Vp_R1. [A],2018,79-79 [15]徐永平,王丽丽,李晓宇.The safety of bacteriophage in food applications[A],2018,90-90 [16]徐永平,王丽丽,李晓宇.Reviewing and thinking on the achievements of bacteriophage research in China during the 1950s[A],2018,91-91 [17]王丽丽,李晓宇,徐永平.Characterization of endolysin LysD2 combat multidrug-resistant gram-negative and gram-positive pathogens[A],2018,112-112 [18]王丽丽,李晓宇,徐永平.Efficacy and safety of a bovine-associated Staphylococcus aureus phage cocktail in mice of mastitis[A],2018,119-119 [19]He, Dongye,Zhang, Ping,Sai, Xuan,Li, Xiaoyu,Wang, Lili,Xu, Yongping.Camellia euphlebia flower extract inhibits oleic acid-induced lipid accumulation via reduction of lipogenesis in HepG2 cells[J],EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE,2018,17:1-8 [20]付丽娜,徐永平,李晓宇,渠坤丽,张楠,王佳宁,王丽丽.噬菌体控制致病性大肠杆菌的研究进展[J],畜牧与兽医,2017,49(12):140-144 [21]He, Dongye,Zhang, Ping,Sai, Xuan,Li, Xiaoyu,Wang, Lili,Xu, Yongping.Hypolipidemic Activity of Camellia euphlebia Flower Extract in High-fat-fed Mice[J],PLANT FOODS FOR HUMAN NUTRITION,2017,72(4):372-379 [22]渠坤丽,丛聪,王丽丽,李晓宇,袁玉玉,张美霞,徐永平.用噬菌体破解细菌生物被膜的研究进展[J],中国抗生素杂志,2017,42(10):849-857 [23]付丽娜,王丽丽,李晓宇,赵红,袁玉玉,丛聪,渠坤丽,徐永平.噬菌体对三大耐药菌的防控作用研究进展[J],中国抗生素杂志,2017,42(10):836-841 [24]袁玉玉,丛聪,王丽丽,李晓宇,渠坤丽,耿慧君,赵红,徐永平.噬菌体与抗菌剂联合应用研究进展[J],中国抗生素杂志,2017,42(10):842-848 [25]王佳宁,徐永平,李晓宇,陈岩,张楠,周通,曲芳京,贾藏藏,王丽丽.畜禽粪便抗生素残留及其对环境的影响[J],畜牧与兽医,2017,49(10):140-144 [26]Pu, Hongyu,Li, Xiaoyu,Du, Qingbo,Cui, Hao,Xu, Yongping.Research Progress in the Application of Chinese Herbal Medicines in Aquaculture: A Review[J],ENGINEERING,2017,3(5):731-737 [27]赵红,徐永平,李晓宇,付丽娜,袁玉玉,渠坤丽,王丽丽.应用噬菌体防治食源性致病菌的研究进展[J],中国抗生素杂志,2017,42(9):737-741 [28]丛聪,袁玉玉,渠坤丽,耿慧君,王丽丽,李晓宇,徐永平.关于噬菌体实用保藏方法的研究进展[J],中国抗生素杂志,2017,42(9):742-748 [29]张美霞,耿慧君,王丽丽,李晓宇,徐永平.哈维弧菌对水产动物的致病性及其噬菌体防控研究进展[J],中国抗生素杂志,2017,42(9):717-723,前插1-前插2 [30]耿慧君,张美霞,徐永平,王丽丽,袁玉玉,丛聪,李晓宇.噬菌体在奶牛乳腺炎防控中的应用[J],中国抗生素杂志,2017,42(9):724-730 [31]任宏宇,李振,徐永平,王丽丽,袁玉玉,李晓宇.应用噬菌体保障即食食品安全的研究进展[J],中国抗生素杂志,2017,42(9):731-736 [32]马超,丛聪,王丽丽,李晓宇,徐永平.噬菌体控制植物细菌性疾病的研究进展[J],中国抗生素杂志,2017,42(9):749-754 [33]Wang, Lili,Qu, Kunli,Li, Xiaoyu,Cao, Zhenhui,Wang, Xitao,Li, Zhen,Song, Yaxiong,Xu, Yongping.Use of Bacteriophages to Control Escherichia coli O157:H7 in Domestic Ruminants, Meat Products, and Fruits and Vegetables[J],FOODBORNE PATHOGENS AND DISEASE,2017,14(9):483-493 [34]周通,徐永平,王丽丽,陈岩,张楠,王佳宁,贾藏藏,曲芳京,李晓宇.地衣芽胞杆菌在植物病害生物防治中的应用[J],生物资源,2017,39(2):85-92 [35]渠坤丽,徐永平,李振,张建成,宋亚雄,付丽娜,王丽丽,李晓宇.提高噬菌体裂解酶抗菌活性的研究进展[J],微生物学杂志,2017,37(1):88-93 [36]王晓丽,续繁星,张恒慧,李晓宇.胡萝卜苹果复合酒发酵工艺的初步研究[J],中国酿造,2017,35(12):180-183 [37]张楠,陈岩,王丽丽,李晓宇,王佳宁,周通,曲芳京,徐永平.多粘类芽胞杆菌对植物土传病害的防控及促生长作用研究进展[J],微生物学杂志,2017,37(5):91-97 [38]李晓宇,王丽丽,徐永平.抗黄海希瓦氏特异性卵黄抗体对刺参被动免疫保护效果及机理研究[A],2017,123-123 [39]李晓宇,王丽丽,徐永平.抗哈维弧菌特异性卵黄抗体对红鳍东方鲀的被动保护效果研究[A],2017,130-130 [40]徐永平,王丽丽,李晓宇.特异性卵黄抗体作为抗生素替代品的研究与应用[A],2017,137-137 [41]He, Dongye,Wang, Lili,Wang, Liping,Li, Xiaoyu,Xu, Yongping.Spectroscopic studies on the interactions between novel bisnaphthalimide derivatives and calf thymus DNA[J],JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,2017,166:333-340 [42]王熙涛,李淑英,王丽丽,李晓宇,徐永平.刺参海带饲料原料褐藻胶降解菌的分离与鉴定[J],微生物学杂志,2016,36(6):61-67 [43]李晶泉,徐永平,王熙涛,李媛,王丽丽,李晓宇.抗金黄色葡萄球菌单链抗体(scFv)的原核表达及蛋白纯化[J],生物技术通报,2016,32(11):194-201 [44]Wang, Xitao,Wang, Lili,Li, Xiaoyu,Xu, Yongping.Response surface methodology based optimization for degradation of align in Laminaria japonica feedstuff via fermentation by Bacillus in Apostichopus japonicas farming[J],ELECTRONIC JOURNAL OF BIOTECHNOLOGY,2016,22:1-8 [45]Li, Xiaoyu,Wang, Ni,Xu, Yongping,Yao, Ying,Wang, Xitao,Zhen, Yuhong,Thacker, Philip A.,Wang, Lili,Shi, Ming,Zhao, Junjun,Zong, Ying.Chicken egg yolk antibodies (IgY) modulate the intestinal mucosal immune response in a mouse model of Salmonella typhimurium infection[J],INTERNATIONAL IMMUNOPHARMACOLOGY,2016,36:305-314 [46]Wang, Chao,Song, Xinbo,Han, Zhuo,Li, Xiaoyu,Xu, Yongping,Xiao, Yi.Monitoring Nitric Oxide in Subcellular Compartments by Hybrid Probe Based on Rhodamine Spirolactam and SNAP-tag[J],ACS CHEMICAL BIOLOGY,2016,11(7):2033-2040 [47]Li, Jingquan,Xu, Yongping,Wang, Xitao,Li, Yuan,Wang, Lili,Li, Xiaoyu.Construction and characterization of a highly reactive chicken-derived single-chain variable fragment (scFv) antibody against Staphylococcus aureus developed with the T7 phage display system[J],INTERNATIONAL IMMUNOPHARMACOLOGY,2016,35:149-154 [48]李媛,徐永平,王丽丽,姚营,靖凯霖,李晓宇.药效营养品IgY在动物饲料与疾病防治中的应用[J],黑龙江畜牧兽医,2016,09:190-193+287 [49]贺栋业,张萍,罗新星,李晓宇,王丽丽,李淑英,徐永平.抗抑郁药用植物研究进展[J],现代生物医学进展,2016,16(13):2552-2558 [50]靖凯霖,徐永平,李媛,姚营,王丽丽,张美霞,尹婷慧,李晓宇.卵黄抗体在水产养殖病害防治及水产品保鲜中的应用研究进展[J],水产科学,2016,35(2):185-190 [51]宋亚雄,王丽丽,李晓宇,张建城,李振,张楠,李淑英,徐永平.噬菌体在畜禽细菌性疾病控制中应用研究进展[J],动物医学进展,2016,37(3):91-94 [52]徐永平,王丽丽,李晓宇.卵黄抗体防治水产养殖病害及在水产品保鲜中的应用[J],水产科学,2016,35(2):185-190 [53]贺栋业,李晓宇,王丽丽,张萍,李淑英,徐永平.金花茶化学成分及药理作用研究进展[J],中国实验方剂学杂志,2016,22(3):231-234 [54]徐永平,王丽丽,李晓宇.抗西瓜蔓枯病优势菌的筛选及其生物有机肥的制备[A],第四届环渤海微生物会议,2016 [55]李晓宇,徐永平,王丽丽.Preparation and characterization of specific egg yolk immunoglobulin against Edwardsiella tarda in turbot (Scophthalmus maximus)[A],The XXV world’s poultry congress,2016,520-520 [56]徐永平,李晓宇,王丽丽.The resource utilization of chicken manure in livestock breeding industry[A],2016,519-519 [57]徐永平,李晓宇,王丽丽.Safe disposal of dead animal carcass by co- composting with animal waste and their utilization as a new source of bio-organic fertilizer[A],2016,519-519 [58]王丽丽,李晓宇,徐永平.The preparation of a rice blast -resisting biological organic fertilizer from swine manur[A],2016,520-520 [59]Li, Xiaoyu,Jing, Kailin,Wang, Xitao,Li, Yuan,Zhang, Meixia,Li, Zhen,Xu, Le,Wang, Lili,Xu, Yongping.Protective effects of chicken egg yolk antibody (IgY) against experimental Vibrio splendidus infection in the sea cucumber (Apostichopus japonicus)[J],FISH & SHELLFISH IMMUNOLOGY,2016,48:105-111 [60]张恒慧,续繁星,李晓宇,任晓莉,王晓丽,徐永平.高密度双菌型复合微生态制剂发酵条件的研究[J],食品研究与开发,2015,36(23):153-157 [61]Li, Jianguang,Xu, Yongping,Jin, Liji,Li, Xiaoyu.Effects of a probiotic mixture (Bacillus subtilis YB-1 and Bacillus cereus YB-2) on disease resistance and non-specific immunity of sea cucumber, Apostichopus japonicus (Selenka)[J],AQUACULTURE RESEARCH,2015,46(12):3008-3019 [62]王佳宁,徐永平,龚改林,张楠,王丽丽,李晓宇.貂粪堆肥专用复合菌剂的制备及效果评估[A],第十八次全国环境微生物学学术研讨会,2015,149-150 [63]张楠,徐永平,王丽丽,李晓宇,王佳宁,续彦龙.抗小麦纹枯病优势菌的筛选及其生物有机肥的制备[A],第十八次全国环境微生物学学术研讨会,2015,148-149 [64]李晓宇,包永明,李宁,谢健.改革生物化学实验教学提高学生综合素质[J],实验科学与技术,2015,13(5):100-101,104 [65]付丽娜,徐永平,王丽丽,李晓宇,于小娟,张楠.一种新型致病性大肠杆菌的分离方法[A],中国食品科学技术学会第十二届年会暨第八届中美食品业高层论坛论文集中国食品科学技术学会,2015,51-52 [66]张美霞,徐永平,李晓宇,李媛,靖凯霖,徐乐,尹婷慧.抗红鳍东方鲀\ 相关热点
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