个人简历

个人简介
Personal Profile
李娜，2016年1月博士毕业于中国科学院大连化学物理研究所生物化工专业，2017年4月至2019年12月先后在美国南达科他大学的生物医学工程系和美国芝加哥大学的生物科学部从事博士后工作。2020年1月开始就职于大连理工大学电子信息与电气工程学部生物医学工程学院。主要从事基于干细胞分化的血管组织工程构建和血管生物力学的研究工作。作为主要参与人参与国家自然基金项目2项，美国心脏协会基金项目1项以及美国南达科他州项目1项。目前在Cardiovascular Research, Journal of Materials Chemistry B, Materials Science and Engineering C等国际期刊发表SCI论文12篇，其中第一作者文章9篇。申报国家发明专利2项，其中1项已经获批。参与编写两本专著，已由科学出版社出版。
教育经历
2011.9 2016.1 中国科学院大学 生物化工 博士
2007.9 2009.6 吉林大学 药物分析学 硕士
2003.9 2007.7 吉林大学 药学 学士
2000.9 2003.6 吉林市磐石市第一中学 无
工作经历
2020.1 至今 大连理工大学 副教授
2019.3 2019.12 美国芝加哥大学 博士后
2017.4 2019.3 美国南达科他大学 博士后
2011.10 2015.11 中国科学院大连化物所 助理研究员
2009.11 2011.10 中国科学院大连化物所 研究实习员

研究领域

血管生物力学
血管组织工程""

近期论文

1) Sanyour H, Li N(co-first author), Rickel A, Torres HM, Anderson RH, Miles MR, Childs JD, Francis KR, Tao JN, Hong ZK. Statin mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration, Journal of Physiology-London, 2020, doi.org/10.1113/JP279528.
2) Li N, Rickel A, Sanyour H, Hong ZK. Vessel Graft Fabricated by the On-site Differentiation of Human Mesenchymal Stem Cells Toward Vascular Cells on Vascular Extracellular Matrix Scaffold under Mechanical Stimulations in Bioreactor, Journal of Materials Chemistry B, 2019,7: 2703-2713.
3) Sanyour H, Li N(co-first author), Rickel A, Childs JD, Kinser CN, Hong ZK. Membrane Cholesterol and Substrate Stiffness Coordinate to Induce the Remodeling of Cytoskeleton and Alteration in Biomechanics of Vascular Smooth Muscle Cell, Cardiovascular Research, 2019, 115:1369-1380.
4) Li N, Xue FX, Zhang H, Sanyour H, Rickel A, Uttecht A, Fanta B, Hu JL, Hong ZK. Fabrication and Characterization of Pectin Hydrogel Nanofiber Scaffolds for Differentiation of Mesenchymal Stem Cells into Vascular Cells, ACS Biomaterials Science & Engineering, 2019, 5: 6511-6519.
5) Li N, Sanyour H, Remund T, Kelly P, Hong ZK. Vascular Extracellular Matrix and Fibroblasts-coculture Directed Differentiation of Human Mesenchymal Stem Cells toward Smooth Muscle-like Cells for Vascular Tissue Engineering, Materials Science and Engineering C, 2018, 93:61-69.
6) Li N, Sui ZG, Liu Y, Wang DD, Ge GB, Yang L. A Fast Screening Model for Drug Permeability Assessment Based on Native Small Intestinal Extracellular Matrix, RSC Advances, 2018, 8:34514-34524.
7) Wang DD, Liu Y, Li N, Zhang Y, Jin Q, Hao DC, Piao HL, Dai ZR, Ge GB, Yang L. Induction of CYP1A1 Increases Gefitinib-induced Oxidative Stress and Apoptosis in A549 Cells, Toxicology in Vitro, 2017, 44: 36-43.
8) Wang DD, Jin Q, Hou J, Feng L, Li N, Li SY, Zhou Q, Zou LW, Ge GB, Wang JG, Yang L, Highly Sensitive and Selective Detection of Human Carboxylesterase 1 Activity by Liquid Chromatography with Fluorescence Detection, Journal of Chromatography B, 2016, 1008: 212-218.
9) Li N, Wang DD, Ge GB, Wang XL, Liu Y, Yang L. Ginsenoside Metabolites Inhibit P-Glycoprotein in Vitro and in Situ Using Three Absorption Models, Planta Medica,2014,4:290-296.
10) Li N, Wang DD, Sui ZG, Qi XY, Ji LY, Wang XL, Yang L. Development of An Improved 3D in Vitro Intestinal Mucosa Model for Drug Absorption Evaluation, Tissue Engineering, 2013, 9: 708-719.
11) Sui ZG, Li N, Liu ZQ, Yan J, Liu ZY, Metabolite Profiling of Aconitine in Stomach after Oral Administration by Liquid Chromatography/electrospray Ionization/multiple-stage Tandem Mass Spectrometry, Xenobiotica, 2013,43: 628-635.
12）Li N, Tsao R, Sui ZG, Ma JW, Liu ZQ, Liu ZY. Intestinal Transport of Pure Diester-type Alkaloids from an Aconite Extract across the Caco-2 Cell Monolayer Model, Planta Medica, 2012, 7: 692-697.