韩璐璐
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个人简介Personal Profile韩璐璐,“兴辽人才”计划青年拔尖人才,“星海优青”计划入选者。主持国家自然科学基金(面上)、自然科学基金青年基金、中国博士后科学基金特别资助、中国博士后科学基金等项目,作为项目骨干参加“十三五”国家重点研发计划项目1项。在Biomaterials (IF 10.273)、Chemistry of Materials (IF 10.159)、ACS Applied Materials & Interfaces (IF 8.456)、Acta Biomaterialia (IF 6.638)、Biomacromolecules (IF 5.667)等期刊上发表SCI论文30余篇,总被引用近700次。申请国际PCT专利1项、授权中国发明专利多项。现为Frontiers in Bioengineering and Biotechnology杂志(IF=5.122)编委,曾获中、韩生物材料学会“青年科学家奖”。截至2019年底,指导硕士研究生13名,已毕业硕士5名,其中优秀毕业生4名,优秀率达80%。指导博士研究生3名,共获2项国家奖学金。欢迎具有生物工程、生物化工、材料、化工、生物等背景的硕士和博士研究生报考。教育经历2009.9 2012.7 辽宁省辽阳市辽化高中 理科2002.9 2006.7 湖南大学 高分子材料 学士2006.9 2012.3 浙江大学 材料学 博士工作经历2014.7 至今 大连理工大学生命 科学学院与技术 讲师2012.8 2014.7 大连理工大学生命 科学学院与技术 博士后专利 利用多酚类化合物在材料表面实现血小板图案化的方法 环糊精修饰磁性纳米吸附剂的制备方法及其在血液透析吸附系统中的应用 科研项目 毛细流道束仿生粘性识别表面及其循坏肿瘤细胞在线捕获性能研究, 国家自然科学基金项目, 2017/08/17, 进行 仿红细胞的体内隐形磷脂/聚电解质复合靶向癌症载体, 国务院其他部门, 2014/07/07, 进行 补体相容的磷脂/聚电解质复合生物活性仿膜, 国务院其他部门, 2013/09/01-2014/06/18, 完成 补体相容的磷脂/聚电解质复合生物活性仿生膜, 国家自然科学基金项目, 2013/09/25-2016/12/31, 完成 治疗肝衰竭肾衰竭血液净化新技术及新产品, 省、市、自治区科技项目, 2018/01/01, 进行 高性能吸附剂关键技术研发及产业化, 国家科技部 , 2016/07/28, 进行 其他奖励 2019 Igem 国际遗传工程大赛 国际金奖 (2019年) 第五届辽宁省“互联网+大学生创新创业大赛 优秀创新创业导师 (2019年) 优秀班主任 (2017年) 中、韩生物材料学会“青年科学家奖” (2016年) 校生物制药工程研究论文比赛优秀指导教师 (2016年)研究领域
1. 血液中循环癌细胞的识别及检测主要研究新型生物材料对血液中扩散癌细胞的抓捕及检测。2. 去除血液毒素的生物医用材料研究新型生物材料去除血液中蛋白结合的疏水毒素,解决临床上此类毒素难以去除的问题。3. 血液相容性医用材料设计血液相容的抗凝血或抗补体激活的生物材料表面,解决血液接触材料引起的凝血、炎症反应等一系列问题。"研究领域 1. Capture and detection of circulating tumor cellsConstruction of new biomaterials or biotechnology for capture and detection of circulating tumor cells.2. Biomedical materials for removal of blood toxinsDesign and synthesize polymer materials for removal of blood hydrophobic toxins bound to plasma proteins.3. Hemocompatible biomaterialsDesign of anticoagulant or anti-complement activated biomaterial surfaces."近期论文
[1]Zang, Berlin,Ren, Jun,Li, Da,Huang, Chundong,Ma, Ha,Peng, Qiang,Ji, Fangling,Han, Lulu,Jia, Lingyun.Freezing-assisted synthesis of covalent C-C inked bivalent and bispecific nanobodies[J],ORGANIC & BIOMOLECULAR CHEMISTRY,2019,17(2):257-263 [2]Xu, Li,Wang, Rou,Cao, Hanyu,Xu, Ting,Han, Lulu,Huang, Chundong,Jia, Lingyun.A facile method to oriented immobilization of His-tagged BirA on Co3+ -NTA agarose beads[J],ENZYME AND MICROBIAL TECHNOLOGY,2019,120:36-42 [3]Yang, Liwei,Sun, He,Jiang, Wenning,Xu, Ting,Song, Bing,Peng, Ruilian,Han, Lulu,Jia, Lingyun.A Chemical Method for Specific Capture of Circulating Tumor Cells Using Label-Free Polyphenol-Functionalized Films[J],CHEMISTRY OF MATERIALS,2018,30(13):4372-4382 [4]Yang, Liwei,Han, Lulu,Jia, Lingyun.Galloyl groups-regulated fibrinogen conformation: Understanding antiplatelet adhesion on tannic acid coating[J],ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,2018,255 [5]Li Jingyu,Han Lulu,Liu Shuxin,He Sai,Cao Yaming,Xie Jian,Jia Lingyun.Removal of indoxyl sulfate by water-soluble poly-cyclodextrins in dialysis.[J],Colloids and surfaces. B, Biointerfaces,2018,164:406-413 [6]韩璐璐,贾凌云.Galloyl groups-regulated fibrinogen conformation: Understanding antiplatelet adhesion on tannic acid coating[A],ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,2018,255:495-495 [7]Han, Lulu,Liu, Qi,Yang, Liwei,Ye, Tong,He, Zhien,Jia, Lingyun.Facile Oriented Immobilization of Histidine-Tagged Proteins on Nonfouling Cobalt Polyphenolic Self-Assembly Surfaces[J],ACS BIOMATERIALS SCIENCE & ENGINEERING,2017,3(12):3328-3337 [8]Yang, Liwei,Han, Lulu,Jia, Lingyun.Novel platelet-repellent polyphenolic surfaces and their micropattern for platelet adhesion detection[J],ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,2017,253 [9]Yang, Liwei,Han, Lulu,Jia, Lingyun.A Novel Platelet-Repellent Polyphenolic Surface and Its Micropattern for Platelet Adhesion Detection[J],ACS APPLIED MATERIALS & INTERFACES,2016,8(40):26570-26577 [10]韩璐璐,韦厚良,贾凌云.自组装石墨烯凝胶对血液中胆红素的去除[A],2016,1-1 [11]杨立为,韩璐璐,贾凌云.基于单宁酸自组装膜循环肿瘤细胞高效捕捉与无损释放[A],2016,1-1 [12]Han, Lulu,Chu, Simin,Wei, Houliang,Ren, Jun,Xu, Li,Jia, Lingyun.Functionalized Magnetic Fe3O4-beta-Cyclodextran Nanoparticles for Efficient Removal of Bilirubin[J],JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2016,16(6):5537-5545 [13]贾凌云,韩璐璐.Functionalized Magnetic Fe3O4-beta-Cyclodextran Nanoparticals for Efficient Removal of Bilirubin[J],JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2016,6(16):5537-5545 [14]贾凌云,韩璐璐.Coating process and stability of metal-polyphenol film[J],Colloids and Surfaces A: Physicochemical and Engineering Aspects,2016,484(484):197-205 [15]Yang, Liwei,Han, Lulu,Ren, Jun,Wei, Houliang,Jia, Lingyun.Coating process and stability of metal-polyphenol film[J],COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2015,484:197-205 [16]Wei, Houliang,Han, Lulu,Tang, Yongchao,Ren, Jun,Zhao, Zongbin,Jia, Lingyun.Highly flexible heparin-modified chitosan/graphene oxide hybrid hydrogel as a super bilirubin adsorbent with excellent hemocompatibility[J],JOURNAL OF MATERIALS CHEMISTRY B,2015,3(8):1646-1654 [17]Wei, Houliang,Han, Lulu,Ren, Jun,Jia, Lingyun.Anticoagulant Surface Coating Using Composite Polysaccharides with Embedded Heparin-Releasing Mesoporous Silica[J],ACS APPLIED MATERIALS & INTERFACES,2013,5(23):12571-12578 [18]Wei, Houliang,Ren, Jun,Han, Bo,Xu, Li,Han, Lulu,Jia, Lingyun.Stability of polydopamine and poly(DOPA) melanin-like films on the surface of polymer membranes under strongly acidic and alkaline conditions[J],COLLOIDS AND SURFACES B-BIOINTERFACES,2013,110:22-28 相关热点
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