个人简历

学历 \r
2019-2012 澳门科技大学 / 中药学 / 博士学位 \r
2006- 2009 南京医科大学 / 药理学(国家重点学科) / 医学硕士学位 \r
2001- 2006 武汉科技大学 / 临床医学 / 医学学士学位 \r
2002- 2006 武汉科技大学 / 英语 / 文学学士学位 (第二学位)\r
教学经验 \r
2019.7- 现职 澳门科技大学 / 中医药学院 / 副教授 \r
2012.9- 2019.6 澳门科技大学 / 中医药学院 / 助理教授\r
2009.4- 2009.7 上海药明康德新药开发有限公司 / 研发生物学部 / 研究员\r
教学科目 病理学；药理学；西医外科学总论；中西医结合研究进展；\r
食品毒理学

研究领域

""1. 腎病\r
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2.糖尿病\r
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3.中藥藥理學\r
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4.活細胞及組織固相色譜技術""""

近期论文

期刊文章(*通讯作者，#共同第一作者):\r
68).. Tingting Zhao, Junling Gu, Huixia Zhang, Zhe Wang, Wenqian Zhang, Yong-Hua Zhao,YingZheng,WeiZhang,HuaZhou,GuilinZhang,QingminSun,EnchaoZhou*, Zhilong Liu*, Youhua Xu*. Sodium Butyrate Modulated Mitochondria Function in High-Insulin induced HepG2 Cells Dysfunction. Oxidative Medicine and Cellular Longevity.2020;2020:1904609.(https://doi.org/10.1155/2020/1904609) [SCI impact factor 2019: 5.076, ranked the 56th in 195 journals (top 28.72%) of categoryCELLBIOLOGY]. \r
67). WeiHuang*,ChenlinGao,LupingZhou,JunlingGu,huiwenxu,QinWan,YangLong, Li Chai, Youhua Xu*, Yong Xu*. Short-chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43-mediated Inhibition of oxidative stress and NF- κ B Signaling.OxidativeMedicineandCellularLongevity.2020(inpress) [SCI impact factor 2019: 5.076, ranked the 56th in 195 journals (top 28.72%) of categoryCELLBIOLOGY].\r
66). Tingting Zhao, Zhe Wang, Zhilong Liu, Youhua Xu*. Pivotal Role Of The Interaction Between Herbal Medicines And Gut Microbiota On Disease Treatment. Current Drug Target. Current Drug Targets. 2020 Mar 24. doi: 10.2174/1389450121666200324151530.[Inpress] [SCI impact factor 2019: 2.632, ranked the 144th in 270 journals (top 53.33%) of categoryPHARMACOLOGY&PHARMACY].\r
65). Xie L, Zhai R, Chen T, Gao C, Xue R, Wang N, Wang J*, Xu Y, Gui D*. Panax notoginseng ameliorates podocyte EMT by targeting the Wnt/β-catenin signaling pathway in STZ-induced diabetic rats. Drug Design Development and Therapy. 2020Feb5;14:527-538. [SCI impact factor 2019: 3.216, ranked the 99th in 270 journals (top 36.67%) of categoryPHARMACOLOGY&PHARMACY]. \r
64). Xue R, Zhai R, Xie L, Zheng Z, Jian G, Chen T,Su J, Gao C, Wang N, Yang X*, Xu Y*, Gui D*. Xuesaitong protects podocytes from apoptosis in diabetic rats through modulating PTEN-PDK1-Akt-mTOR pathway. Journal of Diabetes Research. 2020 Jan21;2020:9309768. [SCI impact factor 2019: 2.965, ranked the 72nd in 138 journals (top 52.17%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL]. \r
63). Xia ZY, Luo C, Liu BW, Bian XQ, Li Y, Pang AM, Xu YH, Tan HM*, Zhao YH*. Shengui Sansheng Pulvis maintains blood-brain barrier integrity by vasoactive intestinal peptideafterischemicstroke.Phytomedicine.2020Feb;67:153158. [SCI impact factor 2019: 4.268, ranked the 2nd in 28 journals (top 7.14%) of categoryINTEGRATIVE&COMPLEMENTARYMEDICINE]. 62). Gao C, Rao M, Huang W, Wan Q, Yan P, Long Y, Guo M, Xu YH*, Xu Y*. Resistant starch ameliorated insulin resistant in patients of type 2 diabetes with obesity: a systematic review and meta-analysis. Lipids in Health and Disease. 2019 Nov 24;18(1):205. [SCI impact factor 2019: 2.906, ranked the 47th in 89 journals (top 52.81%) of categoryNUTRITION&DIETETICS].\r
61). Junling Gu, Man Guo, Yong Xu*, Youhua Xu. Diabetic kidney disease:recent advances in treatment. Chinese Journal of Diabetes Mellitus. 2019;11(10):645-648. [InChinese] 顾峻菱，郭曼，徐勇*，徐友华。糖尿病肾脏疾病治疗策略研究进展。中华糖 尿病杂志。2019;11(10):645-648.\r
60). Junling Gu, Wei Huang, Wenqian Zhang, Tingting Zhao, Chenlin Gao, Wenjun Gan, Mingyue Rao, Qing Chen, Man Guo, Yong Xu*, You-Hua Xu*. Sodium butyrate alleviates high-glucose-induced renal glomerular endothelial cells damage via inhibitingpyroptosis.InternationalImmunopharmacology.2019Oct;75:105832. [SCI impact factor 2019: 3.943, ranked the 63rd in 270 journals (top 23.33%) of categoryPHARMACOLOGY&PHARMACY]. \r
59). WenqianZhang,TingtingZhao,DingkunGui,ChenlinGao,Junling Gu,WenjunGan, Wei Huang, Yong Xu, Hua Zhou, Weini Chen, Zhilong Liu*, Youhua Xu*. Sodium ButyrateImproves Liver Glycogen Metabolism in Type 2 Diabetes Mellitus. Journal ofAgriculturalandFoodChemistry.2019Jul10;67(27):7694-7705. [SCI impact factor 2019: 4.192, ranked the 4th in 58 journals (top 6.90%) of categoryAGRICULTURE,MULTIDISPLINARY]. \r
58). Chenlin Gao,Chen Jiao,Fang Fan, Yang Long, Shi Tang, Jiang Chunxia, Jiying Wang, Youhua Xu*, and Yong Xu*. RIPK2-mediated autophagy and negatively-regulated ROS-NLRP3 inflammasome signaling in GMCs stimulated with high glucose. MediatorsofInflammation.2019;2019:6207563. [SCI impact factor 2019: 3.758, ranked the 63rd in 158 journals (top 39.87%) of\r
categoryIMMUNOLOGY].\r
57. Wenjun Gan, Chenlin Gao, Wenqian Zhang, Junling Gu, Tingting Zhao, Hengli Guo, Hua Zhou, Yong Xu, Lili Yu, Lifang Li, Dingkun Gui**, Youhua Xu*. Kuwanon G promoted Acetylcholine production in advanced glycation end products-induced HT22cells.ExperimentalandTherapeuticMedicine.2019.(Inpress) [SCI impact factor 2019: 1.785, ranked the 105th in 138 journals (top 76.09%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL]. 56). Wenqian Zhang, Tingting Zhao, Yonghua Zhao, Dingkun Gui, Youhua Xu*. AdvancedGlycationEndProductsin ChineseMedicineMediatedAging Diseases:A Review.CurrentVascularPharmacology.2020;18:322-333. [SCI impact factor 2019: 2.672, ranked the 32nd in 65 journals (top 49.23%) of categoryPERIPHERALVASCULARDISEASE].\r
55).. Tang D, Cao DM, Tan LF, Xu YH, Duan TT, Zhu Q*, Wang SM*. Simultaneous determination of 8 bioactive isoflavonoids in Astragali Radix by UHPLC equipped with core-shell column. China Journal of Chinese Materia Medica. 2019 Apr;44(7):1410-1415.[InChinese] 汤丹，曹东敏，谭兰芳，徐友华，段婷婷，朱荃*，王淑美*。基于核壳色谱技 术的黄芪中 8 种异黄酮活性成分的快速定量分析。 中 国 中 药 杂 志 。 2019 Apr;44(7):1410-1415.\r
54).. Zhai RN, Jian GH, Chen T, Xie L, Xue R, Gao CT, Wang NS*, Xu YH*, Gui DK*. Astragalus membranaceus and Panax notoginseng, the novel renoprotective compound, synergistically protect against podocyte injury in streptozotocin-induced diabetic rats. Journal of Diabetes Research. 2019 Apr 16;2019:1602892. [SCI impact factor 2019: 2.965, ranked the 72nd in 138 journals (top 52.17%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL].\r
53). Zheng ZG, Xu YH, Liu F, Zhao TT, Wang RX, Huang PY, Wang RS, Yang AP, Zhu Q*. Screening bioactive components of Glycyrrhiza uralensis Fisch. with isolated perfusedlungextractionandHPLCESI-MSnanalysis.JournalofPharmaceuticaland BiomedicalAnalysis.2019;169:127-132. [SCI impact factor 2019: 3.209, ranked the 26th in 86 journals (top 30.23%) of categoryCHEMISTRY,ANALYTICAL].\r
52). Zhu TT, Wang HL, Zhong X, Huang W, Deng X, Guo HL, Xiong JF, Xu YH*, Fan JM*. Rg1 attenuates High Glucose-induced Endothelial Barrier Dysfunction in the HUVECs by protecting the endothelial glycocalyx. Experimental and Therapeutic Medicine.2019;17:3727-3733. [SCI impact factor 2019: 1.785, ranked the 105th in 138 journals (top 76.09%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL].\r
51). Tang D*, Zhu JX, Nie H, He B, Xu YH, Zhu Q*. Simple and efficient approach for enrichment of major isoflavonoids from Astragalus membranaceus with macroporous resins and their nephroprotective activities. Industrial Crops and Products.2018;125:276-283. [SCI impact factor 2018: 4.191, ranked the 3rd in 89 journals (top 3.37%) of categoryAGRONOMY]. \r
50). XuYH*,GaoCL, GuoHL, Zhang WQ, Huang W,Tang SS, Gan WJ,XuY,ZhouH, Zhu Q. Sodium Butyrate Supplementation Ameliorates Diabetic Inflammation in db/db Mice.JournalofEndocrinology.2018;238(3):231-244. [SCI impact factor 2018: 4.381, ranked the 31st in 145 journals (top 21.38%) of categoryENDOCRINOLOGY&METABOLISM].\r
49). DengX,HuangW,PengJ,ZhuTT,SunXL,ZhouXY ,YangH,XiongJF,HeHQ,XuYH*, He YZ*. Irisin alleviates advanced glycation end products-induced inflammation\r
and endothelial dysfunction via inhibiting ROS-NLRP3 inflammasome signaling. Inflammation.2018;41(1):260-275. [SCI impact factor 2018: 2.939, ranked the 92nd in 158 journals (top 58.23%) of categoryIMMUNOLOGY]. \r
48. TangD,ShenYB,WangZH,HeB,XuYH,NieH*,ZhuQ*.RapidAnalysisandGuided Isolation of Astragalus Isoflavonoids by UHPLC-DAD-MSn and Their Cellular AntioxidantDefenseonHigh GlucoseInducedMesangialCellsDysfunction.Journal ofAgriculturalandFoodChemistry.2018;66(5):1105-1113. [SCI impact factor 2018: 3.571, ranked the 3rd in 57 journals (top 5.26%) of categoryAGRICULTURE,MULTIDISPLINARY]. \r
47.Zhou LP , Huang W, Xu YH, Gao CL, Zhang T, Guo M, Liu Y, Ding JY , Qin LD, Xu ZH, YangL,XuY*.SweettastereceptorsmediatedROS-NLRP3inflammasomesignaling activation: implications for diabetic nephropathy. Journal of Diabetes Research. 2018;2018:7078214. [SCI impact factor 2018: 3.040, ranked the 62nd in 136 journals (top 45.59%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL].\r
46.Huang W, Xu Y, Xu YH, Zhou LP, Gao CL. Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro. Diabetes. 2018, 67(Supplement 1):92-OR. (doi: 10.2337/db18-92-OR)[ConferenceAbstract] [SCI impact factor 2018: 7.199, ranked the 11th in 145 journals (top 7.59%) of categoryENDOCRINOLOGY&METABOLISM]. \r
45). Zhou LP, Huang W, Xu Y*, Xu YH, Long Y, Gao CL. Role of sweet taste receptors in the activation of NLRP3 inflammasome signaling in diabetic kidney disease. ChineseJournalofEndocrinologyandMetabolism.2018;34(7):587-593.[InChinese] 周路平，黄炜，徐勇*，徐友华，龙洋，高陈林。甜味受体在糖尿病肾脏疾病 ROS-NLRP3 炎 症 信 号 活 化 中 的 作 用 研 究 。 中 华 内 分 泌 代 谢 杂 志 。 2018;34(7):587-593.\r
44). Huang W, Zhou LP, Xu Y*, Xu YH, Long Y, Gao CL. Effects of short-chain fatty acids onoxidativestressandinflammationinglomerularmesangialcellsinducedbyhigh glucose. Chinese Journal of Endocrinology and Metabolism. 2018,34(3): 239-245. [InChinese]\r
黄炜，周路平，徐勇，徐友华，龙洋，高陈林。短链脂肪酸对高糖诱导的肾系 膜细胞氧化应激-炎症的影响。 中 华 内 分 泌 代 谢 杂 志 。 2018,34(3):239-245. \r
43). Tang SS,XuYH*. Study progressof Chinese Medicines on treating diabetes and its underlying influence on gut microbiota. Lishizhen Medicine and Mareria Medica Research.2018;29(6):1434-1437.[InChinese] 唐珊珊，徐友华*。中药治疗糖尿病及对肠道菌群影响的研究进展。 时 珍 国 医 国 药 。2018;29(6):1434-1437. \r
42). Tang SS, Xu YH*. Research Progress of Traditional Chinese Medicine in Treating Autoimmune Diseases through Modulating Neutrophil Activity. New Chinese Medicine.2018;50(5):184-189.[InChinese] 唐珊珊，徐友华*。中药通过调节中性粒细胞活性治疗自身免疫性疾病的研究 进展。 新 中 医 。2018;50(5):184-189.\r
41). Huang W, Zhou LP , Guo HL, Xu YH*, Xu Y*. The Role of Short-Chain Fatty Acids in Kidney Injury Induced by Gut-derived Inflammatory Response. Metabolism. 2017;68:20-30. [SCI impact factor 2017: 5.963, ranked the 19th in 142 journals (13.38%) of categoryENDOCRINOLOGY&METABOLISM].\r
40). Xu YH*, Zhou H, Zhu Q. The Impact of Microbiota-Gut-Brain Axis on Diabetic Cognition Impairment. Frontiers in Aging Neuroscience. 2017;9:106. doi: 10.3389/fnagi.2017.00106.eCollection2017. [SCI impactfactor 2017: 3.582, ranked the 14th in 53 journals (26.42%) of category GERIATRICS&GERONTOLOGY].\r
39). Huang W, Guo HL, Deng X, Zhu TT, Xiong JF, Xu YH*, Xu Y*. Short-chain fatty acids inhibit oxidative stress and inflammation in mesangial cells induced by high glucose and lipopolysaccharide. Experimental and Clinical Endocrinology & Diabetes.2017;125:98-105. [SCI impact factor 2017: 1.623, ranked the 120th in 142 journals (84.51%) of categoryNDOCRINOLOGY&METABOLISM]. \r
38). Li YH, Huang W, Xu YH, Zhou LP , Liang YL, Gao CL, Yang L, Xu Y*. CYLD deubiquitinase negatively regulates high glucose-induced NF-kB inflammatory signalinginmesangialcells.BioMedResearchInternational.2017;2017:3982906. [SCI impact factor 2017: 2.583, ranked the 66th in 161 journals (40.99%) of categoryBIOTECHNOLOGY&APPLIEDMICROBIOLOGY].\r
37). Huang W, Zhou LP, Xu Y*, Xu YH*, Gao CL. The role and mechanism of GPR43-beta-arrestin-2 mediated by short-chain fatty acids in regulating inflammatory signaling of diabetic nephropathy. Diabetes-Metabolism Research andReviews.2017;33(SupplementS1):e2948.[ConferenceAbstract] [SCI impact factor 2017: 3.904, ranked the 39th in 142 journals (27.46%) of categoryENDOCRINOLOGY&METABOLISM]. \r
36). Guo HL, Xu YH*. Role of Advanced Glycation End Products in the Progression of Diabetes Mellitus. Global Journal of Obesity, Diabetes and Metabolic Syndrome. 2017;4(1):024-035.\r
35). GuoHL,XuYH*,HuangW,ZhouH,ZhengZg,ZhaoYh,HeB,ZhuTt,TangSs,ZhuQ. Kuwanon G preserves LPS-induced disruption of gut epithelial barrier in vitro. Molecules.2016;21:1597.doi:10.3390/molecules21111597. [SCI impactfactor 2016: 2.861, ranked the 17th in 59 journals (28.81%) of category CHEMISTRY,ORGANIC]. \r
34). Huang W, Xu Y*, Xu YH*. Short-chain fatty acids inhibit oxidative stress and inflammation in mesangial cells induced by high glucose and lipopolysaccharide. Diabetes-Metabolism Research and Reviews. 2016;32(Suppl.2):5-6. [Conference Abstract] [SCIimpactfactor2016:3.263,rankedthe61st in138journals(44.20%)ofcategory ENDOCRINOLOGY&METABOLISM].\r
33). Zhang Q, Zhao YH*, Xu YH, Chen ZW, Liu NW, Ke CC, Liu BW, Wu WK. Sodium ferulate and n-butylidenephthalate combined with bone marrow stromal cells (BMSCs) improve the therapeutic effects of angiogenesis and neurogenesis after ratfocalcerebralischemia.JournalofTranslationalMedicine.2016;14:223. [SCI impact factor 2016: 3.786, ranked the 30th in 128 journals (23.44%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL]. \r
32). ZhaoYH*,ZhangQ,ChenZW,LiuNW,KeCC,XuYH,WuWK.Simvastatincombined with bone marrow stromal cells treatment activates astrocytes to ameliorate neurological function after ischemic stroke in rats. Turkish Journal of Biology. 2016;40:519-528. [SCI impactfactor 2016: 1.038, ranked the 58th in 85 journals (68.24%) of category BIOLOGY]. \r
31). Xu YH*, Xiong JF, Zhao YH, He B, Zheng ZG, Chu GJ, Zhu Q*. Calycosin re-balances advanced glycation end products-induced glucose uptake dysfunction of hepatocyteinvitro.AmericanJournalofChineseMedicine.2015;43(6):1191-1210.\r
[SCI impact factor 2015: 2.959, ranked the 3rd in 24 journals (12.50%) of category INTEGRATIVE&COMPLEMENTARYMEDICINE]. \r
30).XuYH*,XiongJF,WangSS,TangD,WangRS,ZhuQ.CalycosinenteredHUVECsand ameliorated AGEs-promoted cell apoptosis via the Bcl-2 pathway. Journal of NaturalMedicines.2014;68(1):163-72. [SCI impactfactor 2014: 1.593, ranked the 40th in 59 journals (67.80%) of category CHEMISTRY,MEDICINAL]. \r
29). Xu YH*, Lin J, Wang SS, Xiong JF, Zhu Q. Combined estrogen replacement therapy onmetaboliccontrolinpostmenopausalwomenwithdiabetesmellitus.Kaohsiung JournalofMedicalSciences.2014;30(7):350-61. [SCI impact factor 2014: 0.803, ranked the 107th in 123 journals (86.99%) of categoryMEDICINE,RESEARCH&EXPERIMENTAL].\r
28). Xiong JF, Xu YH*, Zhu Q. Anti-Inflammation effects of Radix Astragali Plays an ImportantRoleinAmelioratingType2DiabetesMellitus.GlobalJournalofObesity, DiabetesandMetabolicSyndrome.2014;1(1):030-034. \r
27). Lin J, Zuo GY*, Xu YH*, Xiong JF, Zheng ZG, Wang SS, Zhu Q. Estrogen Reduces Advanced Glycation End Products Induced HUVEC Inflammation Via NF-kappa B Pathway.LatinAmericanJournalofPharmacy.2014;33(1):93-100. [SCI impact factor 2014: 0.372, ranked the 247th in 255 journals (96.86%) of categoryPHARMACOLOGY&PHARMACY]. \r
26). Zhao YH*, Lai W, Xu YH, Li LM, Chen ZW, Wu WK. Exogenous and endogenous therapeutic effects of combination Sodium Ferulate and bone marrow stromal cells (BMSCs) treatment enhance neurogenesis after rat focal cerebral ischemia. MetabolicBrainDisease.2013;28(4):655-66. [SCI impact factor 2013: 2.398, ranked the 72th in 124 journals (58.06%) of categoryENDOCRINOLOGY&METABOLISM]. \r
25). Wu AG, Duan TT, Tang D, Xu YH, Feng L, Zheng ZG, Zhu JX, Wang RS, Zhu Q*. Determination of Nitric Oxide-Derived Nitrite and Nitrate in Biological Samples by HPLCCoupledtoNitriteOxidation.Chromatographia.2013;76:1649-1655. [SCI impactfactor 2013: 1.370, ranked the 49th in 76 journals (64.47%) of category CHEMISTRY,ANALYTICAL]. \r
24). Tang D*, Zhu JX, Wu AG, Xu YH, Duan TT, Zheng ZG, Wang RS, Li D, Zhu Q*. Pre-column incubation followed by fast liquid chromatography analysis for rapid screening ofnaturalmethylglyoxal scavengersdirectlyfromherbal medicines:case study of Polygonum cuspidatum. Journal of Chromatography A. 2013;1286:102-110. [SCI impact factor 2013: 4.258, ranked the 6th in 76 journals (7.89%) of category CHEMISTRY,ANALYTICAL]. \r
23). Zheng ZG, Duan TT, He B, Tang D, Jia XB, Wang RS, Zhu JX, Xu YH, Zhu Q*, Feng L. Macrophage biospecific extraction and HPLC-ESI-MSn analysis for screening immunological active components in Smilacis Glabrae Rhizoma. Journal of PharmaceuticalandBiomedicalAnalysis.2013;77:44-48. [SCI impactfactor2013:2.829, rankedthe22nd in 76journals(28.95%)ofcategory CHEMISTRY,ANALYTICAL]. \r
22). Wan R, Guo R, Chen C, Jin L, Zhu C, Zhang QC, Xu YH, Li SN*. Urocortin increased LPS-induced endothelial permeability by regulating the cadherin-catenin complex via corticotrophin-releasing hormone receptor 2. Journal of Cellular Physiology. 2013;228(6):1295-1303. [SCI impactfactor 2013: 3.874, ranked the 14th in 81 journals (17.28%) of category PHYSIOLOGY].\r
21). Zhao YH*, Guan Y, Xu YH, Li Y, Wu WK. Sodium Ferulate combined with bone marrow stromal cell treatment ameliorating rat brain ischemic injury after stroke. BrainResearch.2012;1450:157-165. [SCI impact factor 2012: 2.879, ranked the 126th in 252 journals (50.00%) of categoryNEUROSCIENCES]. \r
20). Feng L, Xu YH, Wang SS, Au-Yeung W, Zheng ZG, Wang RS, Zhu Q*, Xiang P. Preventative effects of 4,4’-diphenylmethane-bis(methyl) carbamate isolated from cortex mori on human umbilical vein endothelial cell dysfunction induced by advancedglycationendproducts.PhytotherapyResearch.2012;26(3):412-419. [SCI impact factor 2012: 2.068, ranked the 145th in 261 journals (55.56%) of categoryPHARMACOLOGY&PHARMACY]. \r
19). Qin WY, He B, Bei Y, Wang RS, Feng L, Xu YH, Zhu JX, Zheng ZG, Zhu Q, Nie H*. Protective Effects of Danggui Buxue Tang on a Human Umbilical Vein Endothelialcell Damage Induced by Advanced Glycation End Products. Pharmacology&Pharmacy.2012;3(2):224-233. \r
18). Feng L, Xu YH, Wang SS, Au-Yeung W, Zheng ZG, Zhu Q*, Xiang P. Competitive binding between 4,4’-diphenylmethane-bis(methyl) carbamate and RAGE ligand MG-H1 on human umbilical vein endothelial cell by cell membrane chromatography. Journal of Chromatography B, Analytical Technologies in the BiomedicalandLifeSciences.2012;881-882:55-62. [SCI impactfactor 2012: 2.487, ranked the 29th in 75 journals (38.67%) of category CHEMISTRY,ANALYTICAL]. \r
17). Au-Yeung W, Feng L, Xu YH, Wang SS, Wang RS, Zhu Q*, Xiang P. Comparision of anti-non smallcell lung cancercompound corosolicacidin Prunella vulgarisL.from different regions. China Journal of Traditional Chinese Medicine and Pharmacy. 2012;(6):1571-1574.[InChinese] 欧阳慧，封亮，徐友华，王珊珊，王汝上，朱荃*，项平。不同产地夏枯草抗 非小细胞肺癌成分科罗索酸的差异比较。 中 华 中 医 药 杂 志 。 2012;(6):1571-1574. \r
16). Wang SS, Xu YH, Feng L, Zhu Q*, He B. A PKC-beta inhibitor prompts the HUVECs apoptosis-induced by advanced glycation end products. Pharmazie. 2011;66(11):881-887. [SCI impact factor 2011: 1.006, ranked the 94th in 154 journals (61.04%) of categoryCHEMISTRY,MULTIDISCIPLINARY]. \r
15). XuYH,FengL,WangSS,ZhuQ*,LinJ,LouCH,XiangP,HeB,ZhengZG,TangD,Zuo GY. Phytoestrogen calycosin-7-O-β-D-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage. Journal of Cellular Biochemistry. 2011;112(10):2953-2965. [SCI impact factor 2011: 2.868, ranked the 142th in 290 journals (48.97%) of categoryBIOCHEMISTRY&MOLECULARBIOLOGY]. \r
14). Xu YH, Feng L, Wang SS, Zhu Q*, Zheng ZG, Xiang P, He B, Tang D. Calycosin protects HUVECs from advanced glycation end products-induced macrophage infiltration.JournalofEthnopharmacolog.2011;137(1):359-70. [SCI impact factor 2011: 3.014, ranked the 4th in 22 journals (18.18%) of category INTEGRATIVE&COMPLEMENTARYMEDICINE]. \r
13). Jin L, Zhang QC, Guo R, Wang LN, Wang JJ, Wan R, Zhang RJ, Xu YH, Li SN*. Different effects of corticotropin-releasing factor and urocortin 2 on apoptosis of prostate cancer cells in vitro. Journal of Molecular Endocrinology. 2011;47(2):219-227. [SCI impact factor 2011: 3.485, ranked the 40th in 122 journals (32.79%) of categoryENDOCRINOLOGY&METABOLISM]. \r
12). FengL,Au-YeungW,XuYH,WangSS,ZhuQ*,XiangP.OleanolicacidfromPrunella\r
Vulgaris L. induces SPC-A-1 cell line apoptosis via regulation of Bax, Bad and Bcl-2 expression.AsianPacificJournalofCancerPrevention.2011;12(2):403-408. [SCI impact factor 2011: 0.659, ranked the 175th in 196 journals (89.29%) of categoryONCOLOGY]. \r
11). Xu YH, Wang SS, Feng L, Zhu Q*, Xiang P, He B. Blockade of PKC-beta protects HUVECfromadvancedglycationendproductsinduced inflammation.International Immunopharmacology.2010;10(12):1552-1559. [SCI impact factor 2010: 2.325, ranked the 128th in 252 journals (50.79%) of categoryPHARMACOLOGY&PHARMACY]. \r
10). Zhao YH*, Xu YH, Guan Y, Xiang P. Effects of Yinian Jiangya Decoction containing serum on cytokines secretion of vascular endothelium of spontaneously hypertensiverats.ChineseJournalofIntegrativeMedicine.2010;16(4):344-347. [SCI impactfactor 2010: 0.578, ranked the 18th in 21 journals (85.71%) of category INTEGRATIVE&COMPLEMENTARYMEDICINE]. \r
9). Zhang RJ#, Xu YH#, Fu H, Wang JJ, Jin L, Li SN*. Urocortin induced expression of COX-2 and ICAM-1 via corticotrophin-releasing factor type 2 receptor in rat aortic endothelialcells.BritishJournalofPharmacology.2009;158(3):819-829. [SCI impactfactor 2009: 5.204, ranked the 19th in 237 journals (8.02%) of category PHARMACOLOGY&PHARMACY]. \r
8). Xu YH#, Zhang RJ#, Chen J, Zhang QC, Wang JJ, Hu J, Guan XW, Jin L, Fu H, Gui B, GuoYY,LiSN*.Urocortinpromotesthedevelopmentofvasculitisina ratmodelof thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors. BritishJournalofPharmacology.2009;157(8):1368-1379. [SCI impactfactor 2009: 5.204, ranked the 19th in 237 journals (8.02%) of category PHARMACOLOGY&PHARMACY].\r
7). Chen JD, Tao J, Zhang RJ, Xu YH, Soong TW, Li SN*. Urocortin inhibits mesenteric arterial remodeling in spontaneously hypertensive rats. Peptides. 2009;30(6):1117-1123. [SCI impact factor 2009: 2.705, ranked the 93th in 237 journals (39.24%) of categoryPHARMACOLOGY&PHARMACY]. \r
6). Xu YH, Li SN*. Blockade of ICAM-1: a novel way of vasculitis treatment. BiochemicalandBiophysicalResearchCommunications.2009;381(4):459-461. [SCI impact factor 2009: 2.548, ranked the 146th in 283 journals (51.59%) of categoryBIOCHEMISTRY&MOLECULARBIOLOGY]. \r
5). Guan XW, Zhang RJ, Xu YH, Li SN*. Cocaine withdrawal enhances long-term potentiationinrathippocampusviachangingtheactivityofcorticotropin-releasing factorreceptorsubtype2.Neuroscience.2009;161(3):665-670. [SCI impact factor 2009: 3.292, ranked the 90th in 231 journals (38.96%) of categoryNEUROSCIENCES].\r
4). Wu YQ, Zhang RJ, Zhou CH, Xu YH, Guan XW, Hu J, Xu YY, Li SN*. Enhanced expression of vascular cell adhesion molecule-1 by corticotrophin-releasing hormone contributes to progression of atherosclerosis in LDL receptor-deficient mice.Atherosclerosis.2009;203(2):360-370. [SCI impactfactor 2009: 4.522, ranked the 10th in 61 journals (16.39%) of category PERIPHERALVASCULARDISEASE]. \r
3). Wang JJ, Zhang RJ, Xu YH, Zhou HY , Wang B, Li SN*. Genistein inhibits the development of atherosclerosis via inhibiting NF-kappaB and VCAM-1 expression in LDLR knockout mice. Canadian Journal of Physiology and Pharmacology. 2008;86(11):777-784. [SCI impactfactor 2008: 1.763, ranked the 45th in 74 journals (60.81%) of category PHYSIOLOGY].\r
2). WangJJ,XuYH,XuYY ,ZhuHY ,ZhangRJ, ZhangGX,LiSN*.Urocortin’sinhibitionof tumor growth and angiogenesis in hepatocellular carcinoma via corticotrophin-releasing factor receptor 2. Cancer Investigation. 2008;26(4):359-368. [SCI impact factor 2008: 1.976, ranked the 102th in 143 journals (71.33%) of categoryONCOLOGY].\r
1). Wu YQ, Hu J, Zhang RJ, Zhou CH, Xu YH, Guan XW, Li SN*. Enhanced intracellular calcium induced by urocortin is involved in degranulation of rat lung mast cells. CellularPhysiologyandBiochemistry.2008;21(1-3):173-182. [SCI impactfactor 2008: 3.246, ranked the 24th in 74 journals (32.43%) of category PHYSIOLOGY].
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