个人简历

潘胡丹，现为澳门科技大学中药质量研究国家重点实验室助理教授。于 2012 年、
2014 年获得北京中医药大学中医七年制专业（中西医结合方向）学士及硕士学位。2017
年获得澳门科技大学中西医结合专业博士学位。担任世界中医药协会中医药免疫专业委
员会理事，澳门国际风湿病合作联盟理事，粤港澳大湾区风湿免疫医师联盟第一届成员。
主要从事中医治疗风湿病的临床和基础研究，在中医药免疫领域发表文章 20 余篇，总
影响因子（IF）逾 110; 包括 Microbiome, Annals of the Rheumatic Diseases,
Pharmacology & Therapeutics, Phytomedicine 和 Engineering 等国际著名学术期刊。
获国际专利 3 项。在国际知名期刊 Pharmacological research、Engineering、
Phytomedicine 担任编委/青年编委。
学历
2014–2017 澳门科技大学/中西医结合/博士学位
2007–2014 北京中医药大学/中医七年制专业（中西医结合方向）/本科、硕士学位
工作履历
2019-至今 澳门科技大学中药质量研究国家重点实验室 助理教授
2017–2019 澳门科技大学中药质量研究国家重点实验室 博士后
教学科目：中医内科学、中医外科学

研究领域

中西医结合临床、临床免疫、抗关节炎创新药物"专利
1. Methods of identifying a gene associated with a disease or pathological condition of the
disease. Liu L

近期论文

学术成果
1.HDPan#,RJGuo#,YMJu#,QWang#,JieZhu,YingXie,YFZheng,TLi,ZQLiu,LLLu,FLi,B Tong, L Xiao,X Xu, Elaine LHLeung, RZ Li, HM Yang, J Wang, H Zhou, HJ Jia*, Liang Liu*. Asinglebacteriumrestoresthemicrobiomedysbiosistoprotectbonesfromdestruction inaratmodelofrheumatoidarthritis.Microbiome.2019Jul17;7(1):107.
2. Pan HD, Yao XJ, Wang WY, Lau HY, Liu L*. Network pharmacological approach for elucidating the mechanisms of traditional Chinese medicine in treating COVID-19 patients.PharmacolRes.2020Jun20;159:105043.
3. XX Fan#, HD Pan#, Y Li, RJ Guo, Elaine Leung*, L Liu*. Novel therapeutic strategy for
cancer and autoimmune conditions: Modulating cell metabolism and redox capacity. PharmacolTher.2018Nov;191:148-161.
4.HD Pan#, Y Xiao#, WY Wang, RT Ren, Elaine LH Leung*, L Liu*.Traditional Chinese Medicine as a Treatment for Rheumatoid Arthritis: From Empirical Practice to Evidence-basedTherapy.Engineering.doi:org/10.1016/j.eng.2019.01.018.
5. Pan H#, Guo R#, Zhu J#, Wang Q#, Ju Y, Xie Y , Zheng Y, Wang Z, Li T, Liu Z, Lu L, Li F, Tong B, Xiao L, Xu X, Li R, Yuan Z, Yang H, Wang J, Kristiansen K, Jia H*, Liu L*. A gene catalogueoftheSprague-Dawleyratgutmetagenome.Gigascience.2018May1;7(5).
6. Pan, H., Li, R., Li, T., Wang, J., Liu, L*. Whether Probiotic Supplementation Benefits Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis. Engineering, 115-121,doi:10.1016/j.eng.2017.01.006.
7. HD Pan#, YF Zheng, ZQ Liu, ZW Yuan, RT Ren, H Zhou, Y Xie*, L Liu*. Deciphering the
pharmacological mechanism of Guan-Jie-Kang in treating rat adjuvant-induced arthritis usingomicsanalysis.FrontMed.2019May14.doi:10.1007/s11684-018-0676-2.
8. ZouB,ZhangY,LiT,LiuJ,DengW,TanY,YangQ, DingZ,LiaoK,XuJ,PanH,LiX*,LiuL*.
A mutation of cysteine 46 in IKK-β promotes mPGES-1 and caveolin-1 expression to exacerbate osteoclast differentiation and osteolysis. Biochem Pharmacol. 2020 Feb;172:113762.
9.Hu F, Jiang X, Guo C, Li Y, Chen S, Zhang W, Du Y, Wang P, Zheng X, Fang X, Li X, Song J, XieY,HuangF,XueJ,BaiM,JiaY,LiuX,RenL,ZhangX,GuoJ,PanH,SuY,YiH,YeH,Zuo D,Li J,WuH, Wang Y,Li R, Liu L*, Wang XY*, Li Z*. Scavenger receptor-A is a biomarker andeffectorofrheumatoidarthritis:Alarge-scalemulticenterstudy.NatCommun.2020 Apr20;11(1):1911.
10. Zhang N, Zhang H, Law BYK, Dias IRSR, Qiu CL, Zeng W,PanHD, Chen JY,Bai YF,Lv J, Qu LQ,ChenX,HuangQ,ZhangW,YangLJ,YuL,HanY,HuangGX,WangHM,SunXL,Zhang Y, He HQ, Dan Luo W, Xiao Y, Zhou J, Xu T, Huang QC, Wu M, Huang ZS, Liu W, Wong VKW*, Liu L*. Sirtuin 5 deficiency increases disease severity in rats with adjuvant-inducedarthritis.CellMolImmunol.2020Feb25.
11. Wong VKW, Qiu C, Xu SW, Law BYK, Zeng W, Wang H, Michelangeli F, Dias IRSR, Qu YQ, Chan TW, Han Y, Zhang N, Mok SWF, Chen X, Yu L, Pan H, Hamdoun S, Efferth T, Yu WJ, Zhang W, Li Z, Xie Y , Luo R, Jiang Q, Liu L*. Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients andexperimentalarthritisinrats.BrJPharmacol.2019Aug;176(16):2922-2944.
12. WangJ#,WangC#,LiangY,PanH,JiangZ,LiZ,LiY,XiaL,LiuW,ZhangX,LiuZ,JiangM, LiuJ,ZhouH,LiuL*.SerumIgGN-glycansactasnovelserumbiomarkersofankylosing spondylitis.AnnRheumDis.2018Nov15.pii:annrheumdis-2018-213815.doi: 10.1136/annrheumdis-2018-213815.
13. Li RZ, FanXX, Duan FG,Jiang ZB,PanHD, Luo LX, ZhouYL, Li Y,YaoXJ,Leung EL*, Liu L*. Proscillaridin A induces apoptosis and suppresses non-small-cell lung cancer tumor growthviacalcium-inducedDR4upregulation.CellDeathDis.2018Jun13:9(6):696.
14.RYHuang,HDPan,JQWu,HZhou,ZGLi,PQiu,YYZhou,XMChen,ZXXie,YXiao,QC Huang*,LLiu*.Comparisonofcombinationtherapywithmethotrexateandsinomenine orleflunomideforactiverheumatoidarthritis:arandomizedcontrolledclinicaltrial. Phytomedicine.2019Apr;57:403-410.
15.HDPan,XLQi,LWang,JYHe,JLLiu,YBZhang,YTian,XWDuan,HYYang,YPBai*. WhetherFire-needleTherapyBenefitsPlaquePsoriasis： AMulticenter,Randomized,and ControlledTrial.ChinJIntegrMed.2019Apr;25(4):259-263.
16. Su X, Li T, Liu Z, Huang Q, Liao K, Ren R, Lu L, Qi X, Wang M, Chen J, Zhou H, Leung EL, PanHD,LiuJ,WangH,HuangL, LiuL*.LicochalconeAactivatesKeap1-Nrf2signalingto suppressesarthritisviaphosphorylationofp62atserine349.FreeRadic Biol Med.2017 Dec9.pii:S0891-5849(17)31236-4.doi:10.1016/j.freeradbiomed.2017.12.004.
17. LiY#,LeungEL#,PanHD,YaoXJ,HuangQC,WuM,XuT,WangYW,CaiJ,LiRZ,LiuWand Liu L*. Identification of Potential Genetic Causal Variants for Rheumatoid Arthritis by Whole-ExomeSequencing.Oncotarget.2017
18. WangMF#,LiRZ#,LiY,ChengXQ, YangJ,ChenW,FanXX,PanHD,YaoXJ,RT,XQ, LiuL*, Leung EL* & Tang YJ*. J Thorac Dis. Clinical statistics analysis on the characteristics of pneumoconiosisofChineseminerpopulation.2016,8(8):2203-2211.
19. Wang MF, Li RZ, Li Y, Cheng XQ, Yang J, Chen W, Fan XX, Pan HD, Yao XJ, Ren T, Qian X, Liu L, Leung EL* , Tang YJ * . Clinical statistics analysis on the characteristics of pneumoconiosisofChineseminerpopulation.JThoracDis.2016Aug;8(8):2203-11.
20. SuX,HuangQ,ChenJ,WangM,PanH,WangR,ZhouH,ZhouZ,LiuJ,YangF,LiT,LiuL*. Calycosin suppresses expression of pro-in flammatory cytokines via the activation of p62/Nrf2-linked heme oxygenase 1 in rheumatoid arthritis synovial fibroblasts. PharmacolRes.vol.113,PartA,pp.695–704,2016.
21. Wang R, Zhang CY,Bai LP,PanHD, ShuLM, KongAN, Leung EL, Liu L*, Li T*. Flavonoids
derived from liquorice suppress murine macrophage activation by up-regulating heme oxygenase-1 independent of Nrf2 activation. Int Immunopharmacol. 2015 Oct;28(2):917-24.
1.Council Member of the Chinese Medicine and ImmunologyAssociation, World Federation ofChinaImmunologySociety,2018-Present(B06218110151)
2. Council Member of the 1th Board of Specialty Committee of Chinese Medicine Healthcare ProductsofWorldFederationofChinaImmunologySociety,2015-Present
3. 粤港澳大湾区风湿免疫医师联盟第一届成员
4. Council member of the First Council for Macau International Collaboration Alliance for RheumatologyResearch.