个人简历

罗培博士现任澳门中药质量研究国家重点实验室和澳门科技大学药物与健康应用 研究院副教授。先后就读于华西医科大学药学院（获药学－学士学位）和四川大学华西药 学院药理学 5年直博（获药理学－理学博士学位）。2008年 11月-2011年 8月于香港浸会 大学中医药学院教学部从事博士后研究工作。期间一直从事中西药心血药药理评价、配伍 作用和分子细胞水平作用机制研究，已在包括 Mitochondrion, Oxidative Medicine and Cellular Longevity, Talanta, Pharmacological Research, PLoS One, Journal of Pharmacology and Experimental Therapeutics, Journal of Ethnopharmacology, Phytomedicine 等发表多篇学术论 文，其中 SCI 收录论文超过 30 篇，，并获得 4 项已授权国际专利及中国发明专利。近年 来课题组的研究主要集中研究人参，黄芪等心血管活性成分，从线粒体动态，代谢及 DNA 多靶点干预心血管疾病的创新作用机理研究。目前罗博士的研究主要获得澳门科技 发展基金和澳门基金会的资助。
学历 2003年 7月，四川大学药学学士学位 2008年 7月，四川大学药理学博士学位（5年直博）
教学经验
2017.6 – 今 澳门科技大学中药质量研究国家重点实验室 副教授
2011.9 – 2017.6 澳门科技大学中药质量研究国家重点实验室 助理教授
2008.10 – 2011.8 香港浸会大学中医药学院 博士后研究员
2003.10 –2004.12 成都地奥集团公司新药研究所 研究助理
授课科目：药理与毒理学， 临床药理学，中药药理实验方法学

研究领域

心血管药理与线粒体，中药药理学"研究项目(as PI):
1) 2012~2015年 Application of living-cell imaging technique in research of cardiomyocyte mitochondrial dynamics and mechanistic study of anti-ischemia heart disease effects of protopanaxatrioltype Ginsenosides （基于活细胞可视化技术线粒体动态变化的评价及原人参三醇型人参皂苷治疗缺 血性心脏病作用机制的研究）. At Macau University of Science and Technology. Science & Technology Development Fund (FDCT) of Macao SAR （澳门科学技术发展基金）

近期论文

1)Zuo YH, Han QB, Dong GT, Yue RQ, Ren XC, Liu JX, Liu L, Luo P*, Zhou H*. Panax ginseng Polysaccharide Protected H9c2 Cardiomyocyte From Hypoxia/Reoxygenation Injury Through Regulating Mitochondrial Metabolism and RISK Pathway. Frontiers in Physiology. 2018, Jun 15;9:699.
2) Zhang C, Zhang K, Huang F, Feng W, Chen J, Zhang H, Wang J, Luo P, Huang H. Exosomes, the message transporters in vascular calcification. Journal of cellular and molecular medicine. 2018.Review.
3) He L, Zhang Z, Liu Y, Chen D, Yuan M, Dong G, Luo P*, Yan Z*. Rapid discrimination of raw and sulfur-fumigated Smilax glabra based on chemical profiles by UHPLC-QTOFMS/MS coupled with multivariate statistical analysis. Food Research International. 2018, Jun;108:226-236.
4) Li Y, Ren X, Lio C, Sun W, Lai K, Liu Y, Zhang Z, Liang J, Zhou H, Liu L, Huang H, Ren J*, Luo P*, A chlorogenic acid-phospholipid complex ameliorates post-myocardial infarction inflammatory response mediated by mitochondrial reactive oxygen species in SAMP8 mice. Pharmacological Research. 2018, Apr;130:110-122.
5) Xuecong Ren, Li Chen, Jing Xie, Zhifeng Zhang, Gengting Dong, Jie Liang, Liang Liu, 2, Hua Zhou*, Pei Luo*. Resveratrol Ameliorates Mitochondrial Elongation via Drp1/Parkin/PINK1 Signaling in Senescent-like Cardiomyocytes. Oxidative Medicine and Cellular Longevity, 2017.
6) Zhou H, Liu JX, Luo JF, Cheng CS, Leung EL, Li Y, Su XH, Liu ZQ, Chen TB, Duan FG, Dong Y, Zuo YH, Li C, Lio CK, Li T, Luo P, Xie Y, Yao XJ, Wang PX, Liu L*. Suppressing mPGES-1 expression by sinomenine ameliorates inflammation and arthritis. Biochemical Pharmacology. 2017 Oct 15; 142:133-144.
7) Jin Gao, Ming Chen, Xuecong Ren, Xiaobo Zhou, Qiang Shang, WQ Lu, Pei Luo*, ZH Jiang*. Synthesis and cardiomyocyte protection activity of crocetin diamide derivatives. Fitoterapia. 2017 Sep; 121:106-111.
8) QianLong Wan, Jing Xie, XingDe Lia, Tao WJ, LiSheng Ding, Jian Liang, Pei Luo*, Lin-Sen Qing*. An efficient direct competitive nano-ELISA for residual BSA determination in vaccines. Analytical and Bioanalytical Chemistry. 2017 Jul;409(19):4607-4614.
9) QianLong Wan, Jing Xie, XingDe Lia, LiSheng Ding, Jian Liang, Pei Luo*, Lin-Sen Qing*. Development of a nano-SiO2 based enzyme-linked ligand binding assay for the determination of ibuprofen in human urine. Talanta. Volume 167, 15 May 2017, Pages 617622.
10) Huang BM, Xiao SY, Chen TB, Xie Y, Luo P, Liu L, Zhou H*. Purity assessment of ginsenoside Rg1 using quantitative 1H nuclear magnetic resonance. Journal of Pharmaceutical and Biomedical Analysis. 2017 May 30; 139:193-204.
11) Zhifeng Zhang, Yuan Liu, Xuecong Ren, Hua Zhou, KaishunWang, Hao Zhang, and Pei Luo*. Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations. Mediators of Inflammation. Volume 2016, Article ID 7961940, 11 pages
12) Jing Xie, Jie Li, Jian Liang, Pei Luo*, Lin-Sen Qing*, Li-Sheng Ding. Determination of Contents of Catechins in Oolong Teas by Quantitative Analysis of Multi-components Via a Single Marker (QAMS) Method. Food Analytical Methods. 2016, DOI 10.1007/s12161016-0592-5
13) Jianxin Liu, Jinshan Tang, Yihan Zuo, Yang Yu, Pei Luo, Xinsheng Yao,Yan Dong, Peixun Wang, Liang Liu*, Hua Zhou*. Stauntoside B inhibits macrophage activation by inhibiting NF-kappa B andERK MAPK signaling. Pharmacological Research. (2016) 303– 315
14) LUO Pei, DONG Gengting, LIU Liang, ZHOU Hua*. The Long-Term Consumption of Ginseng Extract Reduces the Susceptibility of Intermediate-Aged Hearts to Acute Ischemia Reperfusion Injury. PLoS One. 2015 Dec 9; 10(12):e0144733. doi: 10.1371/journal.pone.0144733.
15) DONG Gengting, CHEN Tingbo, REN Xuecong, ZHANG Zhifeng, HUANG Weixue,
LIU Liang, LUO Pei*, ZHOU Hua*. Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2. Mitochondrion. 2015 Nov 24; 26:7-18.
16)ZHANG Zhifeng, HE Lili, LU Luyang, LIU Yuan, DONG Gengting, MIAO Janhua*, LUO Pei*. Characterization and quantification of the chemical compositions of Scutellariae Barbatae herba and differentiation from its substitute by combining UHPLC–PDA–QTOF– MS/MS with UHPLC–MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 2015 May 10; 109:62-6. doi: 10.1016/j.jpba.2015.02.025.
17) ZHANG ZhiFeng, LIU Yuan, LU Luyang, LUO Pei*. Hepatoprotective activity of Gentiana veitchiorum Hemsl. against carbon tetrachloride induced hepatotoxicity in mice. Chinese Journal of Natural Medicines. 2014, 12(7):0001-0007.
18) LUO Pei, HOU Shaozhen, DONG Gengting, CHEN Tingbo, LIU Liang, ZHOU Hua*. Effectiveness of Panax ginseng on Acute Myocardial Ischemia Reperfusion Injury Was Abolished by Flutamide via Endogenous Testosterone-Mediated Akt Pathway. EvidenceBased Complementary and Alternative Medicine, vol. 2013, Article ID 817826, 9 pages, 2013. doi:10.1155/2013/817826.
19) ZHANG Zhifeng, LU Luyang, LUO Pei, Qing Linsen , LIU Yuan. Two new ursolic acid sapo-nins from Morina nepalensis var. alba Hand-Mazz. Natural Product Research. 2013. DOI: 10.1080/14786419.2013.824441
20) LUO Pei†, WONG Yuanfong†, GE Lin, ZHANG Zhifeng, LIU Yuan, LIU Liang, ZHOU Hua. Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-kappaB activation. Journal of Pharmacology and Experimental Therapeutics. 335, 735-742, 2010.
21) ZHOU Hua, HOU Shaozhen, LUO Pei, ZEN Bao, WANG Jingrong, WONG Yuanfong, JIANG Zhihong, LIU Liang. Ginseng protects rodent hearts from acute myocardial ischemia reperfusion injury through GR/ER-activated RISK pathway in an endothelial NOSdependent mechanism. Journal of Ethnopharmacology. 135, 287-298, 2011.
22) YI Xiaoqin, LI Ting, WANG Jingrong, Wong V.-K., LUO Pei, Wong Y.-F., JIANG Zhihong, LIU Liang, ZHOU Hua. Total ginsenosides increase coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signaling. Phytomedicine. 17, 1006-1015, 2010.
23)ZHANG Zhifeng, LUO Pei, LI Jie, ZHANG Hao*. Comparison of the antiinflammatory activities of three medicinal plants known as \