个人简历

方富贵,女,1973年11月28日生,安徽省潜山县人，教授，博士，硕士生导师，安徽省教坛新秀，安徽农业大学教学名师，动物学会细胞与分子显微技术学分会理事。中国畜牧兽医学会高级会员，中国畜牧兽医学会动物解剖学及组织胚胎学分会常务理事，长期从事动物生殖调控机理与技术、组织学与胚胎学的科研与教学工作，主持安徽省教学研究项目、精品资源共享课程各1项，国家自然科学基金面上项目1项，安徽省自然基金2项，安徽省教育厅自然科研重点项目1项，并参与国家科技部、省科技攻关等多项科研课题，获国家授权专利15项，发表学术论文50余篇，其中SCI收录25篇，参与鉴定科研成果6项，科技成果转化1项。参编教材5部、其中副主编教材1部。参与的科研项目曾获安徽省科技进步一等奖、三等奖,并担当“theriogenology”“JournalofEndocrinologyBMCGenomics杂志的审稿人。
教研工作经历：

国2001.09-2002.07安徽农业大学助教
2002.08－2007.07安徽农业大学讲师
2007.08－2013.12安徽农业大学副教授
2014.01-至今安徽农业大学教授

研究领域

动物生殖调控机理与技术；动物生理生化

近期论文

１.SuS,ZhouX,ZhangX,FangF（correspondingauthor）.Effectofgonadotropin-releasinghormonevaccinationonTlymphocytechangesinmalerats.JournalofReproductiveImmunology120(2017)1–7
２.GaoX,YeJ,YangC,ZhangK,LiX,LuoL,DingJ,LiY,CaoH,LingY,ZhangX,LiuY,FangF（correspondingauthor）,ZhangY.ScreeningandevaluatingoflongnoncodingRNAsinthepubertyofgoats.BMCGenomics.2017Feb14;18(1):164.doi:10.1186/s12864-017-3578-9.
３.YangC,YeJ,LiX,GaoX,ZhangK,LuoL,DingJ,ZhangY,LiY,CaoH,LingY,ZhangX,LiuY,FangF（correspondingauthor）.DNAMethylationPatternsintheHypothalamusofFemalePubertalGoats.PLoSOne.2016Oct27;11(10):e0165327.doi:10.1371/journal.pone.0165327.eCollection2016
４.GaoX,ZhangK,SongM,LiX,LuoL,TianY,ZhangY,LiY,ZhangX,LingY,FangF（correspondingauthor）,LiuY..RoleofNesfatin-1intheReproductiveAxisofMaleRat。Sci.Rep.6,32877;doi:10.1038/srep32877(2016).SciRep.2016Sep7;6:32877.doi:10.1038/srep32877.
５.长链非编码RNA与生殖.高宵宵，杨宸，方富贵（correspondingauthor）.家畜生态学报，2016年2月，37（2）：8－11
６.DNA甲基化与雌性动物初情期的关系.杨宸，高宵宵，方富贵（correspondingauthor）.家畜生态学报，2016年6月,37(6):79-84
７.JiangS,ZhouW,ZhangX,WangD,ZhuH,HongM,GongY,YeJ,FangF（correspondingauthor）.Developmentalexpressionanddistributionofnesfatin-1/NUCB2inthecaninedigestivesystem.ActaHistochem.2016Mar;118(2):90-6.
８.CuiP,YangC,ZhangK,GaoX,LuoL,TianY,SongM,LiuY,ZhangY,LiY,ZhangX,SuS,FangF（correspondingauthor）,DingJ.EffectofestrogenontheexpressionofGnRHandkisspeptininthehypothalamusofratsduringpuberty.Theriogenology.2015，84：1556－1564
9.ShipingSu,XiaoxiaSun1,XiuhongZhou,FuiguiFang（correspondingauthor）andYunshengLi.EffectsofGnRHimmunizationonthereproductiveaxisandthymulin.JournalofEndocrinology(2015)226,93–102.
10.宋敏，田园，方富贵（correspondingauthor）..Nesfatin-1与生殖.生理科学进展，2014,45（6）：439-441
11.田园，宋敏，方富贵（correspondingauthor）.动物初情期表观遗传调控的研究进展.家畜生态学报.2015,36(4):6-9
12.LiuY,TianY,ZhaoX,JiangS,LiF,ZhangY,ZhangX,LiY,ZhouJ,FangF（correspondingauthor）.ImmunizationofdogswithrecombinantgonadotropinreleasinghormoneI(GnRH-I)suppressesthedevelopmentofreproductivefunction.Theriogenology.2015,83:314-319.
13.ShudongJIANG,MeizhenHONG,ShipingSU,MinSONG,YuanTIAN,PeiCUI,ShuangSONG,YaoyaoWANG,FubaoLI,FuguiFANG（correspondingauthor）.EffectofactiveimmunizationagainstGnRH-Ionthereproductivefunctionincat.AnimalScienceJournal.2015Aug;86(8):747-54
14.WenHua,LeiLuo,YuanTian,MinSong,YajieLiu,PeiCui,ShuangSong,ShudongJiang,FubaoLi,FuguiFang（correspondingauthor）.AnalysisoftheserumconcentrationsofkisspeptinandneurokininBinthegeeseduringreproductivecycleandtheirlocalisationintheovary.AnimalreproductionScience.2014,151(1-2):78-84
15.YaLiu,FuguiFang（correspondingauthor）ShudongJiang,YuanTian,Leiluo,MinSong,ShipingSu,YongPu,JieZhou,XiaorongZhang.ReducedConcentrationofAndrostenoneandUp-regulationof3β-hydroxysteroiddehydrogenaseand17β-hydroxysteroiddehydrogenasemRNAlevelsbyActiveImmunizationagainstGonadotropinReleasingHormoneI.ItalianJournalofAnimalScience.2014,13(4):741-745
16.FuguiFang,ShipingSu(equalcontributionauthor),YaLiu,YunhaiZhang,YongPu,XijieZhao,YunshengLi,HongguoCao,JuhuaWang,JieZhou,XiaorongZhang（correspondingauthor）.ImmunizationagainstrecombinantGnRH-Ialtersultrastructureofgonadotropincellinanexperimentalboarmodel.ReproductiveBiologyandEndocrinology,2013,11:63.17.LiY,LiuY,SuS,PuY,ZhangX,FangF,YunshengLi,YaLiu(equalcontributionauthor),ShipingSu(equalcontributionauthor),YongPu,XiaorongZhang,FuguiFang（correspondingauthor）.ImmunizationagainstrecombinantGnRH-Ialterstesticularstructureinanexperimentalboarmodel.Zygote.2015Feb;23(1):125-35
18.SuS,FangF(equalcontributionauthor),LiuY,LiY,RenC,ZhangY*,ZhangX*.ThecompensatoryexpressionofreproductivehormonereceptorsinthethymusofthemaleratfollowingactiveimmunizationagainstGnRH.Generalandcomparativeendocrinology,GenCompEndocrinol.2013,185:57-66.
19.FangF,LiuY,ZhaoX,LiY,ZhangY,ZhangX.TheassociationbetweentesticularghrelinreceptormRNAandserumtestosteronelevelsinimmunocastratedboars.Anim.Reprod.Sci.2012,135(1-4):62-67
20.FuguiFang,XiuhongZhou,FubaoLi,ZhizhongZhang,ShudongJiang.ThehistologicalstructureoftheliverandpancreasanddistributionofglucagonofpancreasintheSiberiantiger(Pantheratigrisaltaica).JournalofAnimalandVeterinaryAdvances.2012,11(16):2885-2889
21.赵熙杰，方富贵（correspondingauthor）.GnRH主动免疫对动物生殖的研究进展.黑龙江动物繁殖.2012,20(6):1-4
22.方富贵，罗英霞，杨静，蒋书东，李福宝.血管活性肠肽及其基因在小鼠卵巢中的定位.中国兽医学报.2012,32(5):783-787.
23.方富贵，杨静，罗英霞，王然，安好峰，李福宝.生长素在不同生理时期小鼠子宫的表达.解剖学杂志，2012,35(2):165-167.
24.蒋书东，戴书俊，方富贵（correspondingauthor），李福宝.黑麂肝、小肠和大肠的组织学结构及Ghrelin的分布.动物学杂志，2012，47(1):36-43.
25.YunhaiZhang,YunshengLi,ZhizhongZhang,ZubingCao,ShudongJiang,JingYang,XiaorongZhang,FuguiFang(correspondingauthor).ThehistologicalstructureandlocationofsubstancePinthedigestivetractoftheSiberiantiger(Pantheratigrisaltaica).JournalofAnimalandVeterinaryAdvances.2012,11(6):735-741.
26.方富贵，杨静，罗英霞，王然，安好峰，李福宝.不同生理时期小鼠卵巢的Ghrelin定位研究.中国农业大学学报.2012,17(1):105-109
27.FangF,WangL,ZhangY,LiY,SuS,ZhangX.RoleofGhrelinonEstrogenandProgesteroneSecretionintheAdultRatOvaryDuringEstrousCycle.SystBiolReprodMed.2011Dec6.2012,58(2):116-9
28.方富贵,张运海,刘亚,苏时萍,蒲勇,李运生,陶勇,章孝荣.重组GnRH主动免疫对公猪体重及生长激素和IGF-I的影响.中国免疫学杂志,2011,27（9）：809-813
29.WangL,FangF(equalcontributionauthor),LiY,ZhangY,PuY,ZhangX.RoleofghrelinontestosteronesecretionandthemRNAexpressionofandrogenreceptorsinadultrattestis.SystemsBiologyinReproductiveMedicine.SystBiolReprodMed.Jun.;57(3):119-123.Epub2011Jan42011Jun;57(3):119-2330.FuguiFang,YaLiu,YongPu,LinWang,SuoluWang,XiaorongZhang.ImmunogenicityofrecombinantMaltose-bindingprotein(MBP)–gonadotropinreleasinghormoneI(GnRH-I).SystemsBiologyinReproductiveMedicine.SystBiolReprodMed.2010Dec;56(6):478-86.Epub2010Sep17.IF=1.847
31.FuguiFang,HaidongLi,YaLiu,YunhaiZhang,YongTao,YunshengLi,HongguoCao,SuoluWang,LinWang,XiaorongZhang.ActiveimmunizationwithrecombinantGnRHfusionproteininboars
reducesbothtesticulardevelopmentandmRNAexpressionlevelsofGnRHreceptorinpituitary.Anim.Reprod.Sci.(2010),119(3-4):275-281
32.方富贵,王琳,王索路,蒲勇,章孝荣,李运生,张运海,陶勇,刘亚,曹鸿国.免疫去势和未去势猪睾丸上生长激素释放肽的定位及其基因表达.解剖学杂志,2010,33(1):29-32.
33.方富贵,王琳,蒲勇,王索路,蒋书东,李运生,任春环，章孝荣.去势对公猪生殖轴上Ghrelin和功能性Ghrelin受体mRNA的影响.西北农林科技大学学报（自然科学版）.2010,38(3):17-22.
34.方富贵,章孝荣.GnRH-I疫苗免疫效果的影响因素、商业化困境与免疫机理的研究进展.畜牧与兽医杂志.2009,28(4):29-31
35.方富贵,蒲勇,王索路,王琳,章孝荣,陶勇,张运海,刘亚,李运生.重组GnRH主动免疫公猪的效果及对垂体GnRH受体、FSHβ和LHβ基因表达的影响.中国免疫学杂志,2009,25(9):824-827
36.方富贵,蒋书东,李梅清,李福宝.鹅下丘脑—垂体—卵巢轴上ghrelin的免疫组化定位.中国兽医杂志,2009,45(5):28-29
37.蒲勇,方富贵,章孝荣.GnRH免疫公猪的研究进展.畜牧与兽医.2009,41(10):90-92.
38.方富贵,章孝荣.GnRH-I疫苗的功能及其应用的研究进展.黑龙江动物繁殖.2009,17(3):6-9
39.FANGFu-gui,YANGYa-ping,LIUYa,ZHANGYun-hai,TAOYong,WANGSuo-lu,PUYong,ZHANGXiao-rong.ImmunizationofMaleMicewithaNewRecombinantGnRHFusionProteinReducestheTesticularFunction.AgriculturalSciencesinChina.2009,8(3):380-385