个人简介
姓名:张明珠,籍贯:望江,于 2010 年考入安庆师范学 院生物科学专业,2014 年考入安徽大学生命科学学院,从事天 然产物食用菌多糖免疫调节活性研究, 并于2016年通过硕博连读转安徽大学化学与化工学院,师从田玉鹏教授。目前工作于安庆师范大学生命科学学院,任专任教师,从事教学科研工作,研究的方向功能小分子探针的生物学应用。教育经历 2010/9-2014/6 安庆师范学院 生物科学 学士 2014/9-2019/6 安徽大学 微生物学转无机化学 硕博连读
研究领域
小分子荧光探针的生物学功能应用
近期论文
1.Mingzhu zhang, et al, Real-time noninvasive monitoring cell mortality using a two-photon emissive probe based on quaternary ammonium. J. Mater. Chem. B, 2018, 6, 4417-4421. 2. Mingzhu zhang, et al, Ultra-bright intercellular lipids pseudo di-BODIPY probe with low molecular weight, high quantum yield and large two-photon action cross-sections. Sens. Actuators B-Chem. 2018, 261, 161–168. 3. Mingzhu zhang, et al, Immunomodulating activity of the polysaccharide TLH-3 from Tricholomalobayense in RAW264.7 macrophages. Int. J. Biol. Macromol. 2018, 107, 2679–2685. 4. Xiaohe Tian, Qiong Zhang, Mingzhu Zhang, et al. Probe for simultaneous membrane and nucleus labeling in living cells and in vivo bioimaging using a two-photon absorption water-soluble Zn(II) terpyridine complex with a reduced p-conjugation system. Chem Sci. 2017, 8(1), 142–149. 5. Xiao Sun, Mingzhu Zhang, et al, A polyethyleneimine-driven self-assembled nanoplatform for fluorescence and MR dual-mode imaging guided cancer chemotherapy. Chemical Engineering Journal 2018, 350, 69–78. 6.Dandan Liu, Mingzhu Zhang, et al. A Series of Zn(II) Terpyridine-Based Nitrate Complexes as Two-Photon Fluorescent Probe for Identifying Apoptotic and Living Cells via Subcellular Immigration. Inorg. Chem. 2018, 57 (13), 7676–7683. 7. Shuyi Chen, Mingzhu Zhang,et al. Rational design of two-photon absorbing dicyanomethylene-4H-chromene derivatives and their application in bioimaging. Dyes and Pigments, 2018, 148, 429-436. 8. Qiong Zhang, Mingzhu Zhang, et al. A series of two-photon absorption organotin (IV) cyano carboxylate derivatives for targeting nuclear and visualization of anticancer activities. Journal of Inorganic Biochemistry 2019, 192,1–6. 9. Yingzhong Zhu, Mingzhu Zhang, et al. NF-κB hijacking theranostic Pt(ІІ) complex: a new avenue in cancer therapy. Theranostics 2019, 9 (8), 2158-2166.