个人简介

研究经历 2017/09-至今，澳门科技大学，中药质量研究国家重点实验室 2016/12-2017/06，华盛顿大学神经内科系，Acting instructor, 导师： Nicholas Poolos 2015/11-2016/12，华盛顿大学药理系博士后，导师：William Catterall 院士 2012/08-2015/10，华盛顿大学生理系博士后，导师：Bertil Hille 院士 2014/02-2014/05，中科院生物物理所访问学者，合作者：徐涛院士 2010/3-2012/06，夏威夷大学女王医学中心博士后，导师：AndreaFleig 教授 ReinholdPenner 教授 2008/11-2009.11，夏威夷大学女王医学中心研究生，导师：AndreaFleig 教授 ReinholdPenner 教授 2005/06–2006/09，中山大学生命科学院，助研，导师：周文良 教育经历 2006/09–2009/12 中山大学 生命科学院 生理学博士 导师：周文良 2003/09–2005/06 中山大学 生命科学院 生理学硕士 导师：周文良 1999/09–2003/06 山西大学 生命科学院 学士

近期论文

发表刊物 1.Yu H, Yuan C, Westenbroek RE, Catterall WA. The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac CaV1.2 calcium channels. J Gen Physiol. 2018 Jun 4;150(6):883-889. 2. Traynor-Kaplan A, Kruse M, Dickson EJ, Dai G, Vivas O, Yu H, Whittington D, Hille B. Fatty-acyl chain profiles of cellular phosphoinositides. Biochim Biophys Acta. 2017 Feb 9;1862(5):513-522. 3. Yang L, Dai DF, Yuan C, Westenbroek RE, Yu H, West N, de la Iglesia HO, Catterall WA. Loss of β-adrenergicstimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failure. Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7976-E7985.4. Yu H*, Benitez SG*, Jung SR, Farias Altamirano LE, Kruse M, Seo JB, Koh D, Muñoz EM, Hille B. GABAergic signaling in the rat pineal gland. J Pineal Res. 2016 Aug;61(1):69-81. (* equal contribution) 5. Dai G, Yu H, Kruse M, Traynor-Kaplan A and Hille B. Osmoregulatory inositol transporter SMIT1 modulates electrical activity by adjusting PI(4,5)P2 levels. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3290-96. Xu X, Ali S, Li Y, Yu H, Zhang M, Lu J, Xu T. 2-Aminoethoxydiphenyl Borate Potentiates CRAC Current by Directly Dilating the Pore of Open Orai1. Sci Rep. 2016 Jul 4;6:29304. 7. Yu H, Dickson EJ, Jung SR, Koh DS, Hille B. High membrane permeability for melatonin. J Gen Physiol 2016 Jan;147(1):63-76 8. Yu H, Seo JB, Jung SR, Koh DS, Hille B. Noradrenaline upregulates T-type calcium channels in rat pinealocytes. J Physiol. 2015 Feb 15;593(4):887-9049. Zhang Z, Faouzi M, Huang J, Geerts D, Yu H, Fleig A, Penner R. N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation. Oncotarget. 2014 Sep 15;5(17):7625-34.10. Zhang Z*, Yu H*, Huang J, Faouzi M, Schmitz C, Penner R, Fleig A. The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels. J Biol Chem. 2014 Feb 21;289(8):5217-27. (* equal contribution)11. Yu H*, Zhang Z*, Lis A, Penner R, Fleig A. TRPM7 is regulated by halides through its kinase domain. Cell Mol Life Sci. 2013 Aug;70(15):2757-71. (* equal contribution) 12. Yu H, Chen S, Yang Z, Pan A, Zhang G, Shan J, Tang X, Zhou W. Trimethyltin chloride induced chloride secretion across rat distal colon. Cell Biol Int 2009 Dec 16;34(1): 99-108. 13. Yang Z*, Yu H*, Pan A, Du J, Ruan Y, Ko W, Chan H, Zhou W. Cellular mechanisms underlying the laxative effect of flavonol naringenin on rat constipation model. PLoS One 2008 Oct 3;3(10):e3348. (* equal contribution) 14. Yang Z, Pan A, Ruan Y, Yu H, Wu Z, Xiang H, Zhou W. Cellular mechanism of adrenalin stimulated chloride secretion via beta-adrenoceptor in T84 cells. Cell Biol Int 2008 Jun;32(6):679-87. Epub 2008 Feb