个人简介

Academic QualificationsBSc, MSc, China Pharmaceutical UniversityMSc, PhD (Hon), University of MacauGuest Researcher, Austrian Institute of TechnologyTeachingGraduate CoursesIntroduction to Research in Medical Administration (CMED710)Research Methodology (CMED729)Across the Gap between Science and Industry (CMED725）Advanced topics in Medicinal Administration (CMED825)

研究领域

Complex systems analysisMedical data miningPharmaceutical innovation management

近期论文

Journals (* corresponding author)1.D.Y. Zhang, Y. Zhang, Y. Gao, X.Y. Chai, R.B. Pi, G. Chan*, Y.J. Hu*, Translating traditional herbal formulas into modern drugs: a network-based analysis of Xiaoyao decoction, Chinese Medicine, 15(1): 1-11, 2020.2.S.Y. Hu, H.L. Zuo, J. Qi, Y.J. Hu*, Yu Boyang*, Analysis of effects of Schisandra in the treatment of myocardial infarction based on three-mode gene ontology network, Frontiers in Pharmacology, 10: 232, 2019.3.G.Y. Li, Y. Zhou, D.M.Y. Sze, C. Liu, Q.R. Zhang, Z.H. Wang, H. Yu, G. Chan, Z.D. Wu, S.B. Su*, Y.J. Hu*, Active ingredients and action mechanisms of Yi Guan Jian Decoction in chronic hepatitis B patients with liver fibrosis, Evidence-Based Complementary and Alternative Medicine, 2408126, 2019.4.Z.H. Wang, H.H. Lin, K.G. Linghu, R.Y. Huang, G.Y. Li, H.L. Zuo, H. Yu, G. Chan, Y.J. Hu*, Novel compound-target interactions prediction for the herbal formula Hua-Yu-Qiang-Shen-Tong-Bi-Fang, Chemical and Pharmaceutical Bulletin, 67(8): 778-785, 2019.5.F.B. Xia, F.G. Xu, H.X. Su, C.W. He, Y.J. Hu*, J.B. Wan*, Quantification of phospholipid fatty acids by chemical isotope labeling coupled with atmospheric pressure gas chromatography quadrupole-time-of-flight mass spectrometry (APGC/Q-TOF MS), Analytica Chimica Acta, 1082: 86-97, 2019.6.Q.R. Zhang, Z.F. Zhong, W. Sang, W. Xiong, H.X. Tao, G.D. Zhao, Z.X. Li, Q.S. Ma, K.W.T. Anfernee, Y.J. Hu*, H. Yu*, Y.T. Wang, Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: combined computational predictions and experimental investigations, Journal of Ethnopharmacology, 228: 200-209, 2019.7.H.L. Zuo, F.Q. Yang*, Y.J. Hu*, Investigation of possible herb-drug interactions for the treatment of cardiovascular diseases, Seminars in Thrombosis and Hemostasis, 45(05): 548-551, 2019.8.J.W. Qv, J.H. Lu, Y.J. Hu*, Research and development of anti-Parkinson’s drugs: an analysis from the perspective of technology flows measured by patent citations. Expert Opinion on Therapeutic Patents, 29(2): 127-135, 2019.9.Z.F. Zhong, Q.R. Zhang, H.X. Tao, W. Sang, L. Cui, W.N. Qiang, W.S. Cheang, Y.J. Hu*, H. Yu*, Y.T. Wang, Anti-inflammatory activities of Sigesbeckia glabrescens Makino: combined in vitro and in silico investigations, Chinese Medicine, 14: 35, 2019.10.R. Jiang, Y.Y. Sun, C.O.L. Ung, X.Y. Dong, X.J. Kong, Y.J. Hu*, R. Shao*, Research and development of mAb drugs in China: a look from policy perspectives, Human Vaccines & Immunotherapeutics, 15(11): 2695-2705,2019.11.J.Z. Yan, H. H Lin, D. Zhao, Y.J. Hu*, R. Shao*, China’s new policy for healthcare cost-control based on global budget: a survey of 110 clinicians in hospitals, BMC Health Services Research, 19(1): 84, 2019.12.S. Li, Y.J. Hu, Network pharmacology: An approach to the analysis of complex systems underlying traditional Chinese medicine, World Journal of Traditional Chinese Medicine, 4(4): 135, 2018.13.H.L. Zuo, Q.R. Zhang, S.B. Su, Q.L. Chen, F.Q. Yang*, Y.J. Hu*, A network pharmacology-based approach to analyse potential targets of traditional herbal formulas: An example of Yu Ping Feng decoction, Scientific Reports, 8: 11418, 2018.14.H.H. Lin, D.F. Ouyang, Y.J. Hu*, Intelligent Classifier: A Tool to Impel Drug Technology Transfer from Academia to Industry, Journal of Pharmaceutical Innovation, 1-8, 2018.15.K.M. Liu, H.H. Lin, R.B. Pi, S.H. Mak, Y.F. Han, Y.J. Hu*, Research and development of anti-Alzheimer’s disease drugs: an update from the perspective of technology flows, Expert Opinion on Therapeutic Patents, 28(4): 341-350, 2018.16.X.J. Kong, Q.R. Zhang, Y.F. Lai, H. Hu, X. Chen, Y.J. Hu*, Global patent landscape of programmed cell death 1: implications of the rapid expansion. Expert Opinion on Therapeutic Patents, 28(1): 69-80, 2018.17.H.H. Lin, L.L. Zhang, Y. Ru, J.J. Lu*, Y.J. Hu*, Network analysis of drug-target interactions: A study on FDA-approved New Molecular Entities between 2000 to 2015, Scientific Reports, 7: 12230, 2017.18.X.J. Kong, J.B. Wan, H. Hu, S.B. Su, Y.J. Hu*, Evolving patterns in a collaboration network of global R&D on monoclonal antibodies, MAbs, 9(7): 1041-1051, 2017.19.Q.R. Zhang, H. Yu, J. Qi, D.S. Tang, X.J. Chen, J.B. Wan, P. Li, H. Hu, Y.T. Wang, Y.J. Hu*, Natural formulas and the nature of formulas: Exploring potential therapeutic targets based on traditional Chinese herbal formulas, Plos One, 12(2): 1-14, 2017.20.Q.R. Zhang, X.J. Kong, H.Y. Xu, Y.T. Wang, Y.J. Hu*, Progress of studies on traditional Chinese medicine-based on complex network analysis, World Journal of Traditional Chinese Medicine, 3: 1-10, 2017.21.J.Y. Ni, J.R. Zhao, C.O.L Ung, Y.J. Hu*, H. Hu, Y.T. Wang, Obstacles and opportunities in Chinese pharmaceutical innovation, Globalization and Health, 13(1): 1-9, 2017.22.J.L. Deng, K.W. Sitou, Y.P. Zhang, R.Yan, Y.J. Hu*, Analyzing the Chinese landscape in anti-diabetic drug research: leading knowledge production institutions and thematic communities, Chinese Medicine, 11: 13, 2016.23.J.Y. Ni, J. B. Wan, X.J. Kong, Y. Cai, F.Q. Yang, Y.T. Wang, Y.J. Hu*, Pharmaceutical technology licensing: An analysis in the field of cardiovascular disease, Journal of Pharmaceutical Innovation, 11(1): 34-45, 2016.24.M. Zhang, X.J. Kong, J. Zheng, J.B. Wan, Y.T. Wang, Y.J. Hu*, R. Shao, Research and development of antibiotics: insights from patents and citation network, Expert Opinion on Therapeutic Patents, 26: 617-627, 2016.25.F. Ding, Q.R. Zhang, C.O.L. Ung, Y.T. Wang, Y.F. Han, Y.J. Hu*, J. Qi, An analysis of chemical ingredients network of Chinese herbal formulae for the treatment of coronary heart disease, Plos One, 10(2): e0116441, 2015.26.X.J. Kong, Y.J. Hu*, Z.F. Cai, F.Q. Yang, Q.R. Zhang, Dendritic-cell-based technology landscape: Insights from patents and citation networks, Human Vaccines & Immunotherapeutics, 11(3):682-688, 2015.27.X.J. Kong, W.X. Zhou, J.B. Wan, Q.R. Zhang, J.Y. Ni, Y.J. Hu*, An integrative thrombosis network: Visualization and topological analysis. Evidence-Based Complementary and Alternative Medicine, 2: 265303, 2015.28.H. You., M. Barber, T. Scherngell, J.Y. Ni, Y.J. Hu*, China’s landscape in oncology drug research: Perspectives from research collaboration networks. Chinese Journal of Cancer Research, 27(2):138-147, 2015.29.Y.J. Hu, T. Scherngell, L. Qiu, Y.T. Wang, R&D internationalisation patterns in the global pharmaceutical industry: Evidence from a network analytic perspective. Technology Analysis & Strategic Management, 27(5):532-549, 2015.30.J.Y. Ni, R. Shao, C.O.L. Ung, Y.T. Wang, Y.J Hu*, Y. Cai, Valuation of pharmaceutical patents: A comprehensive analytical framework based on technological, commercial, and legal factors. Journal of Pharmaceutical Innovation, 10(3):281-285, 2015.31.X.M. Geng, X.J. Kong, H. Hu, J.Y. Chen, F.Q. Yang, H.Y. Liang, X. Chen, Y.J. Hu*, Research and development of therapeutic mAbs: An analysis based on pipeline projects, Human Vaccines & Immunotherapeutics, 11(12):2769-2776, 2015.32.J.C. Xu, X. J. Kong, L. Qiu, X. M. Geng, Y.J. Hu*, Y.T. Wang, Research and development of anti-Alzheimer’s drugs: An analysis based on technology flows measured by patent citations, Expert Opinion on Therapeutic Patents, 7: 1-10, 2014.33.T. Scherngell, M. Borowiecki, Y.J. Hu*, Effects of knowledge capital on total factor productivity in China: a spatial econometric perspective, China Economic Review, 29: 82-94, 2014.34.Y.J. Hu*, T. Scherngell, S. N. Man, Y.T. Wang, Is the United States still dominant in the global pharmaceutical innovation network? Plos One, 8(11), e77247, 2013.35.Y. Guo, Y.J. Hu*, Y.T. Wang, Patent indicators: A window on pharmaceutical market value, Expert Opinion on Therapeutic Patents, 6: 1-6, 2013.36.J.Y. Ni, J.C. Xu, Y.J. Hu*, L. Su, Y.T. Wang, Cross-regional pharmaceutical technology transfer in China: Patterns and proposed investment strategies, Therapeutic Innovation & Regulatory Science, 8: 1-10, 2013.37.J.J. Lu, W. Pan, Y.J. Hu*, Y.T. Wang*, Multi-target drugs: The trend of drug research and development, Plos One, 7(6): 1-6, 2012. (ESI Highly Cited Paper)38.T. Scherngell and Y.J. Hu, Collaborative knowledge production in China: Regional evidence from a gravity model approach, Regional Studies, 45: 755-772, 2011.39.Y.J. Hu, Y. Bian, Y.T. Wang, Opening the “black box” of pharmaceutical patent value: An empirical analysis, Drug Information Journal, 42(6): 561-568, 2008.40.Y.J. Hu, C. O. L. Ung, Y. Bian, Y.T. Wang, The Chinese pharmaceutical market: Dynamics and a proposed investment strategy, Journal of Medical Marketing, 7(1): 18-24, 2007. (Best Paper Award)41.Y.J. Hu, F. Geng, Y. Bian, Y.T. Wang, The Chinese pharmaceutical market: Perspectives of the health consumer, Journal of Medical Marketing, 7(4): 295-300, 2007.42.Y.J. Hu, Y. Bian, Y.T. Wang, Secrets of blockbuster drugs: Data mining for oppositions against patents, Drug Information Journal, 41(3): 425, 2007.Book Chapters1.Y.T. Wang, Y.J. Hu, A.W.K. Chan, Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017.2.H.H Lin, P.P Li, X.J. Kong, J. Cai, S.B. Su, Y.J. Hu*, An analysis of evolutionary conservation based on genomic orthology and protein-protein interaction networks, in Biotechnology in Hong Kong III, United States-China Intellectual Property Institute, Hong Kong, 2017.3.K.W. Sitou, J.B. Wan, M.S.H. Mak, Y.F. Han, Y.J. Hu*, Monitoring drug research on clinical neurology in china: an analysis of institutional leaders and community themes, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 3.4.H.W. Kuok, X.J. Kong, Y.J. Hu*, Y.T. Wang*, China’s landscape of discovering mirnas in cancer, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 4.5.X.J. Kong, H Lu, Q.R. Zhang, H.L. Zuo, Y.J. Hu*, A.W. Chan*, Global landscape of research and development on antibiotics, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 5.6.X.J. Kong, H.Y. Liang, Q.W. Yuan, Y.J. Hu*, Entry inhibitors for aids therapy: a review of research and development projects, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 6.7.T.H. Yin, X.J. Kong, Y.T. Wang, X. Chen, Y.J. Hu*, R. Shao*, Collaboration networks for R&D of monoclonal antibodies: an analysis based on pipeline projects, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 7.8.H.H. Lin, S.Q. Tian, M.S.H. Mak, Y.F. Han, Y.J. Hu*, An analysis of technology flows of antidepressants based on patent citation network, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 9.9.J.Y. Ni, R. Shao, C.O.L. Ung, Y.T. Wang, Y.J. Hu*, Y. Cai, Pharmaceutical patent valuation based on empirical models, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 10.10.J.Y. Ni, Y.J. Hu*, J.B. Wan, T. Scherngell, F. Kwan, Cross-regional pharmaceutical technology transfer in china: an empirical study based on spatial interaction model, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 11.11.M. Wan, J.R. Zhao, B.Y. Zhang, D.N. Yao, Y.J. Hu*, Changing pharmaceutical registration rules in china: latest updates and potential impacts, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 12.12.P.P. Li, H.H. Lin, Y.J. Hu*, Pharmaceutical innovation network: global patterns and the role of China. Innovation Value Chain of Chinese Pharmaceuticals, in Innovation Value Chain of Chinese Pharmaceuticals, United States-China Intellectual Property Institute, New York, 2017, Chapter 13.13.H.W. Kuok, X.J. Kong, Y.J. Hu*, Y.T. Wang, Discovering mirnas in cancer: China’s landscape and the role of Hong Kong, in Biotechnology in Hong Kong, United States-China Intellectual Property Institute, Hong Kong, 2015, Chapter 2.14.Y.Y. Yu, J.J. Liu, L. Qiu, W. Pan, Y.J. Hu, Y.T. Wang, Situation and Outlook on the Market and Intellectual Properties of Anti-cancer Chinese Medicines, in Technologies and Progresses of Advanced Research on Anti-cancer Chinese Medicines, People’s Medical Publishing House, Beijing, 2013.15.Y.T. Wang, Y. Bian, L. Li, Y.J. Hu, The Development of Macao’s Healthcare, in Annual Report on Economy and Society of Macao–Blue Book of Macao 2010, Social Sciences Academic Press, Beijing, 2010.16.Y.J. Hu, R. Shao, R.L. Song, Y. Bian, L.W. Shi, Y.T. Wang, A Study on the Industrial Policy Law of Chinese Pharmaceutical Industry, in Chinese Medical Sciences Collection Series A- Progress in Medicinal Administration Research, University of Macau Publisher, Macau, 2005.