个人简介

高丽萍，女，1962年3月出生，1982年安徽师范大学本科毕业。学士。现为安徽农业大学生命科学学院植物生理教研室主任，教授，硕士生导师。长期从事植物生理学教学管理工作，先后讲授植物生理学、植物生物学、细胞工程学、天然产物开发与研究等课程。参加国家973计划前期研究专项、国家自然科学基金课题，主持安徽省自然科学基金、安徽省教育厅自然科学基金等科研工作。在国内外学术刊物和国际性学术会议上发表有关论文30余篇。获安徽省科学技术二等奖和安徽省自然科学三等奖。目前正开展茶树次生代谢的研究。主要教学经历与成果：长期从事植物生理学、细胞工程学、天然产物化学的教学工作。主持2006年安徽省高等学校省级教学研究“学分制条件下植物生理学精品课程建设”课题主持2007年安徽省高等学校精品课程“植物生理学精品课程”课题；副主编《植物生理学》（ISBN978-7-81117-268-3）中国农业大学出版社；高丽萍、蔡永萍、张玉琼、王云生、张云华、魏晓飞、高俊山,以课程改革和课程网络平台建设为核心全面提升“植物生理学”教学质量,获安徽农业大学2012年校级教学成果二等奖；王云生、高丽萍、蔡永萍、张玉琼、张云华、魏晓飞、高俊山,“植物生理学”网络课程，获安徽农业大学2011年多媒体教育软件一等奖、安徽省教育厅多媒体教育软件评奖二等奖高丽萍、蔡永萍、张玉琼、王云生、张云华、魏晓飞、高俊山,以课程改革和课程网络平台建设为核心全面提升“植物生理学”教学质量,获安徽省教学成果二等奖；获2014年省级教学名师。

研究领域

植物次生代谢

长期从事植物生理学、细胞工程学、天然产物化学的科学研究；近期重点开展植物黄酮类化合物生物合成途径及其调控的分子机制

近期论文

（1）YAJUN LIU,LIPING GAO,TAO XIA*,LEI ZHAO. Investigation of the Site-Specific Accumulation of Catechins in the Tea Plant (Camellia sinensis) via Vanillin-HCl Staining. J of Agric Food Chem(SCI), 2009 （2）Dongqing Yang, Yajun Liu, Meilian Sun, Lei Zhao, Yunsheng Wang, Xiaotian Chen, Chaoling Wei, Liping Gao*, Tao Xia*.Differential gene expression in tea (Camellia sinensis) calli with different morphologies and catechin contents, J of Plant Physiology (SCI)，2012 （3）YunSheng Wang, LiPing Gao, ZhengRong Wang, YaJun Liu, MeiLian Sun, DongQing Yang, ChaoLing Wei, Yu Shan, Tao Xia*, Light-induced expression of genes involved in phenylpropanoid biosynthetic pathways in callus of tea (Camellia sinensis), Scientia Horticulturae (SCI)，2012 （4）XianLin Zhang, YaJun Liu, KeJun Gao，Lei Zhao, Li Liu,YunSheng Wang, MeiLian Sun, LiPing Gao*,Tao Xia*,Characterisation of anthocyanidin reductase from Shuchazao green tea，J Sci Food Agric (SCI)，2012 （5）YunSheng Wang, LiPing Gao, Yu Shan, YaJun Liu, YanWei Tian, Tao Xia*. Influence of shade on flavonoid biosynthesis in tea (Camellia sinensis)，Scientia Horticulturae（SCI），2012 （6）Ya-jun Liu, Liping Gao†, Li Liu , Qin Yang , Zhongwei Lu , Zhiyin Nie , Yunsheng Wang and Tao Xia*，Purification and Characterization of a Novel Galloyltransferase Involved in Catechin Galloylation in the Tea Plant 【Camellia sinensis】. J of Biological Chemistry (SCI), 2012 （7）Lei Zhao, Liping Gao, Hongxue Wang, Xiaotian Chen, Yunsheng Wang, Hua Yang, Chaoling Wei, XiaoChun Wan, Xia T*, The R2R3-MYB, bHLH, WD40 and related transcription factors in flavonoid biosynthesis. Functional & Integrative Genomics(SCI), 2012 （8）Xiaolan Jiang, Yajun Liu, Weiwei Li, Lei Zhao, Fei Meng, Yunsheng Wang, Huarong Tan, Hua Yang, Chaoling Wei, Xiaochun Wan, Liping Gao*,Tao Xia*, Tissue-Specific, Development-Dependent Phenolic Compounds Accumulation Profile and Gene Expression Pattern in Tea Plant 【Camellia sinensis】. PLoS ONE(SCI),2013 (9) Zhongwei Lu, Yajun Liu, Lei Zhao,Xiaolan Jiang, Mingzhuo Li, Yunsheng Wang,Yujiao Xu, Liping Gao*,Tao Xia*. Effect of low-intensity white light mediated de-etiolation on the biosynthesis of polyphenols in tea seedlings, Plant Physiology and Biochemistry(SCI),2014 (10) Yun-Sheng Wang,Yu-Jiao Xu, Li-Ping Gao, Oliver Yu, Xin-Zhen Wang, Xiu-Juan He, Xiao-Lan Jiang,Ya-Jun Liu and Tao Xia*, Functional analysis of Flavonoid 3’,5’-hydroxylase from Tea plant (Camellia sinensis): critical role in the accumulation of catechins, BMC Plant Biology(SCI),2014(11) Yahui Wu, Xiaolan Jiang, Shuxiang Zhang, Xinlong Dai, Yajun Liu, Huarong Tan, Liping Gao*,Tao Xia*, Quanti?cation of ?avonol glycosides in Camellia sinensis by MRM mode of UPLC-QQQ-MS/MS，J of Chromatography B(SCI)，2016(12) Xiaolan Jiang, Yajun Liu†,Yahui Wu ,Huarong Tan, Fei Meng, Yun sheng Wang, Mingzhuo Li, Lei Zhao,Li Liu, Yumei Qian, Liping Gao*,Tao Xia*. Analysis of accumulation patterns and preliminary study on the condensation mechanism of proanthocyanidins in tea plants【Camellia sinensis】, Scientific Reports(SCI),2015（13）Yumei Qian, Xianqian Zhao, Lei Zhao, Lilan Cui, Li Liu, Xiaolan Jiang, Yajun Liu, Liping Gao* , Tao Xia*. Analysis of stereochemistry and biosynthesis of epicatechin in tea plants by chiral phase high performance liquid chromatography, J Chromatography B (SCI),2015（14）Lilan Cui,Shengbo Yao,Xinlong Dai,..Liping Gao*,Tao Xia*.Identification of UDP-glycosyltransferases involved in the biosynthesis of astringent taste compounds in tea, J Exp Bot (SCI),2016（15）Xiaolan Jiang, Hua Hou, Shuxiang Zhang, Yajun Liu, Haiyan Wang,Wei-Wei Deng, Shasha Zhou, Yahui Wu, Fangfang Shen, Liping Gao*,Tao Xia*, Comparison of Phenolic Compound Accumulation Profiles in Eight Evergreen Woody Core Eudicots Indicating the Diverse Ecological Adaptability of Camellia sinensis. Scientia Horticulturae(SCI)，2017（16）Mingzhuo Li, Yanzhi Li, Lili Guo, Niandi Gong, Yongzheng Pang, Wenbo Jiang,Yajun Liu, Xiaolan Jiang, Lei Zhao, Yunsheng Wang, De-Yu Xie*, Liping Gao*,Tao Xia*，Functional characterization of tea (Camellia sinensis) MYB4a transcription factor using an integrative approach，Frontiers in Plant Science(SCI)，2017（17）Xianqian Zhao,Peiqiang Wang,Mingzhuo Li, Yeru Wang, Xiaolan Jiang, Lilan Cui, Yumei Qian, Juhua Zhuang, Liping Gao,*and Tao Xia*. Functional Characterization of a New Tea (Camellia sinensis) Flavonoid Glycosyltransferase，J. Agric. Food Chem. (SCI)，2017(18)Xinlong Dai , Juhua Zhuang, Yingling Wu, Peiqiang Wang, Guifu Zhao, Yajun Liu,Xiaolan Jiang, Liping Gao & Tao Xia. Identification of a Flavonoid Glucosyltransferase Involved in 7-OH Site Glycosylation in Tea plants (Camellia sinensis) . Scientific Reports,2017, DOI:10.1038/s41598-017-06453-z(19)Yingling Wu , Wenzhao Wang, Yanzhi Li, Xinlong Dai , Guoliang Ma, Dawei Xing ,Mengqing Zhu, Liping Gao, Tao Xia, Six phenylalanine ammonia-lyases from Camellia sinensis: Evolution,xpression, and kinetics. Plant Physiology and Biochemistry 118 (2017) 413e421(20)Jinxin Xia, Yajun Liu, Shengbo Yao, Ming Li, Mengqing Zhu, Keyi Huang, Liping Gao , Tao Xia .Characterization and Expression Profiling of Camellia sinensis cinnamate 4-hydroxylase genes in phenylpropanoid pathways. Genes,2017,接受 （21）夏涛，高丽萍.类黄酮及茶儿茶素生物合成途径及其调控研究进展. 中国农业科学,2009 （22）夏涛, 高丽萍, 刘亚军, 王云生, 刘莉, 赵磊, 蒋晓岚, 钱玉梅.茶树酯型儿茶素合成代谢途径研究新进展.中国农业科学，2013 （23）Wang P, Zhang L, Jiang X, et al. Evolutionary and functional characterization of leucoanthocyanidin reductases from Camellia sinensis. Planta. 2018;247(1):139-154. doi:10.1007/s00425-017-2771-z（24）Jiang X, Shi Y, Dai X, et al. Four flavonoid glycosyltransferases present in tea overexpressed in model plants Arabidopsis thaliana and Nicotiana tabacum for functional identification. J Chromatogr B Analyt Technol Biomed Life Sci. 2018;1100-1101:148-157. doi:10.1016/j.jchromb.2018.09.033（25）Wang W, Zhou Y, Wu Y, et al. Insight into Catechins Metabolic Pathways of Camellia sinensis Based on Genome and Transcriptome Analysis. J Agric Food Chem. 2018;66(16):4281-4293. doi:10.1021/acs.jafc.8b00946（26）Dai X, Zhao G, Jiao T, et al. Involvement of Three CsRHM Genes from Camellia sinensis in UDP-Rhamnose Biosynthesis. J Agric Food Chem. 2018;66(27):7139-7149. doi:10.1021/acs.jafc.8b01870（27）Qian Y, Zhang S, Yao S, et al. Effects of vitro sucrose on quality components of tea plants (Camellia sinensis) based on transcriptomic and metabolic analysis. BMC Plant Biol. 2018;18(1):121. Published 2018 Jun 18. doi:10.1186/s12870-018-1335-0（28）Zhuang J, Dai X, Zhu M, et al. Evaluation of astringent taste of green tea through mass spectrometry-based targeted metabolic profiling of polyphenols. Food Chem. 2020;305:125507. doi:10.1016/j.foodchem.2019.125507（29）Wang P, Liu Y, Zhang L, et al. Functional demonstration of plant flavonoid carbocations proposed to be involved in the biosynthesis of proanthocyanidins. Plant J. 2020;101(1):18-36. doi:10.1111/tpj.14515（30）Dai X, Liu Y, Zhuang J, et al. Discovery and characterization of tannase genes in plants: roles in hydrolysis of tannins. New Phytol. 2020;226(4):1104-1116. doi:10.1111/nph.16425（31）Wei C, Yang H, Wang S, et al. Draft genome sequence of Camellia sinensis var. sinensis provides insights into the evolution of the tea genome and tea quality. Proc Natl Acad Sci U S A. 2018;115(18):E4151-E4158. doi:10.1073/pnas.1719622115（32）Wu Y, Xing D, Ma G, Dai X, Gao L, Xia T. A variable loop involved in the substrate selectivity of pinoresinol/lariciresinol reductase from Camellia sinensis. Phytochemistry. 2019;162:1-9. doi:10.1016/j.phytochem.2019.02.003（33）Wang P, Ma G, Zhang L, et al. A Sucrose-Induced MYB (SIMYB) Transcription Factor Promoting Proanthocyanidin Accumulation in the Tea Plant ( Camellia sinensis). J Agric Food Chem. 2019;67(5):1418-1428. doi:10.1021/acs.jafc.8b06207（34）Huang K, Li M, Liu Y, et al. Functional Analysis of 3-Dehydroquinate Dehydratase/Shikimate Dehydrogenases Involved in Shikimate Pathway in Camellia sinensis. Front Plant Sci. 2019;10:1268. Published 2019 Oct 11. doi:10.3389/fpls.2019.01268专利：1. 刘新荣（学），高丽萍，夏涛，利用反式白藜芦醇苷水解制备反式白藜芦醇的方法（ZL 2009 1 0116109）2. 刘亚军（学），高丽萍，夏涛，茶树含不同儿茶素含量及组分的细胞系筛选方法，（ZL 2009 1 0116195.5）3. 张宪林（学），高丽萍，夏涛，茶树中二氢黄烷醇4-还原酶/无色花青素还原酶的快速检测方法（ZL2009 10116179.6）4. 高丽萍，夏涛，聂志银，刘亚军,一种酯型儿茶素水解酶检测方法，（ZL 2011 1 0046144.7）5. 高丽萍, 夏涛，刘莉，刘亚军,一种酯型儿茶素合成酶检测方法，(ZL 2011 1 0046171.4)