研究领域
内在无序蛋白的结构、聚集与功能机制蛋白质的折叠机制酶的结构与功能机制
近期论文
1.Ye K, Tu X*, Zhang X*, Shang Q, Liao S,Yu J, Zhang J, Induced Folding Under Membrane Mimetic and Acidic ConditionsImplies Undiscovered Biological Roles of Prokaryotic Ubiquitin-Like Protein Pup.Protein Pept. Lett. (2016), 23, 756-7622.Yang Y, Zhang X, Yin Q,Fang W, Fang Z, Wang X, Zhang X*, Xiao Y*. Amechanism of glucose tolerance and stimulation of GH1 β-glucosidases. Sci. Rep. (2015), 5:17296; doi:10.1038/srep172963.Fang Z, Zhou P, Chang F, Yin Q, Fang W, Yuan J, Zhang X*, Xiao Y*. Structure-based rational design toenhance the solubility and thermostability of a bacterial laccase Lac15. PLoS One (2014), 7, e1024234.Fang Z, Li J, Wang Q, Fang W, Peng H, ZhangX*, XiaoY*.Anovel esterase from a marine metagenomic library exhibiting salt toleranceability. J. Microbiol. Biotechnol. (2014), 24,771-7805.Zhang X*, Dong Y, Yu J, Tu X. Effectsof environmental factors on MSP21-25 aggregation indicate the rolesof hydrophobic and electrostatic interactions in the aggregation process. Eur.Biophys. J. (2014), 43, 1-96.Yu J, Wang C, Hu Y, Dong Y, Wang Y, Tu X, Peng H*, Zhang X*. Purification, crystallization and preliminarycrystallographic analysis of the marine α-amylase AmyP. Acta Cryst. (2013), F69, 263-2667.Zhang X*, Adda CG, Low A, Zhang J, Zhang W, Sun H, Tu X, Anders RF, Norton RS. Role of the helicalstructure of the N-terminal region of Plasmodiumfalciparum merozoite surface protein 2 in fibril formation and membraneinteraction. Biochemistry (2012), 51, 1380-13878.Zhang X, Perugini M, Yao S, Adda CG, Murphy VJ, Low A,Anders RF., Norton RS. Solution conformation, backbone dynamics and lipidbinding of the intrinsically unstructured malaria surface protein MSP2. J. Mol.Biol. (2008), 379, 105-1219.Zhang X, Xu Y, Zhang J, Wu J, Shi Y. Structural and dynamiccharacterization of the acid-unfolded state of hUBF HMG Box 1 provide clues forthe early events in protein folding. Biochemistry (2005), 44, 8117-812510.Zhang X, Zhang J, Li X, Xu J, Huang H, Chen Q, Wu J, Shi Y.Compact molten globule-like state of hUBF HMG Box1 at extremely low pH,Biochim. Biophys. Acta (2005), 1748, 66-73.
