个人简介

肖亚中，男，博士，二级教授，博士生导师。1984年本科毕业于安徽大学生物系生化微生物专业，获学士学位。1994年在中国科技大学获硕士学位。1997-1998年Hong Kong University of Science & Technology生化系任访问学者。2002年毕业于中国科技大学生物化学与分子生物学专业，获博士学位。2005-2006年在美国Florida International University从事博士后研究。学术获奖：肖亚中，方泽民等，海洋微生物来源优质酶蛋白发现、催化机制及理性改造，安徽省科学技术奖，二等奖肖亚中，洪宇植等，漆酶的优质资源发现与高效表达调控机制研究，安徽省科学技术奖，二等奖

研究领域

基因表达调控的分子机制；生物催化；微生物通讯。研究领域包括基因工程、酶与酶工程等。

近期论文

Li J, Xie YN, Wang R, Fang ZM, Fang W, Zhang XC*, Xiao YZ*. (2018) Mechanism of salt induced activity enhancement of a marine derived laccase, Lac15. European Biophysics Journal 47:225-236Chang F, Zhang XB, Pan Y, Lu YX, Fang W, Fang ZM*, Xiao YZ*. (2017) Light induced expression of β-glucosidase in Escherichia coli with autolysis of cell. BMC Biotechnology 17:74-84He C, Li J, Li W, Xue Y, Fang ZM, Fang W, Zhang XC, Wang XT, Xiao YZ*. (2016) Structures of PspAG97A α-glucoside hydrolase reveal a novel mechanism for chloride induced activation. Journal of Structural Biology 196: 426-36Fang W, Yang Y, Zhang XX, Yin Q, Zhang XC, Wang XT, Fang ZM*, Xiao YZ*. (2016) Improve ethanol tolerance of β-glucosidase Bgl1A by semi-rational engineering for the hydrolysis of soybean isoflavone glycosides. Journal of Biotechnology 227: 64-71Yang Y, Zhang XX, Fang W, FangZM, Wang XT, ZhangXC*, Xiao YZ*. (2015) A mechanism of glucose tolerance and stimulation of GH1 β-glucosidases. Scientific Reports 5:17296Fang W, Song R, Zhang XB, Zhang XC, Fang ZM*, Xiao YZ*. (2014) A novel β-glucosidase from Gongronella sp.W5 with high productivity in the hydrolysis of soybean isoflavone glycosides. Journal of Agricultural and Food Chemistry 62: 11688Fang W, Fang ZM, Zhou P, Chang F, Hong YZ, Zhang XC, Peng H, Xiao YZ*. (2012) Evidence for lignin oxidation by the giant panda fecal microbiome. PLoS ONE10.1371/journal.pone.0050312Ji L, Shen Y, Xu LL, Peng BG, Xiao YZ*, Bao XM*. (2011) Enhanced resistance of Saccharomyces cerevisiae to vanillin by expression of lacA from Trametes sp. AH28-2. Bioresource Technology 102: 8105Fang ZM, Li TL, Wang Q, Zhang XC, Peng H, Fang W, Hong YZ, Ge HH, Xiao YZ*. (2011) A bacterial laccase from marine microbial metagenome exhibiting chloride tolerance and dye decolorization ability. Applied Microbiology and Biotechnology (2011) 89:1103 Wei F, Hong YZ, Xiao YZ*, Liu JJ, Yuan J. (2010) Gongronella sp induces overproduction of laccase in Panus rudis. Journal of Basic Microbiology 50:1