个人简介

EducationPh.D. Department of Vascular Surgery, Shanghai Second Medical University, Shanghai, China (1993-1996)M.S. Surgery, Chongqing Medical University, Chongqing, China (1988-1991)B.S. School of Clinical Medicine, Luzhou Medical College, Luzhou, China (1981-1986)Academic and Professional Experience2017.08-present Adjunct Professor, Faculty of Health Sciences, University of Macau2016.02-present President, Southwest Medical University, Luzhou, China2011.11-2016.02 Dean/Chair Professor, Affiliated Hospital of Luzhou Medical College, China2005.09-2008.10 Dean, Nursing School of Luzhou Medical College, China2002.05-2011.11 Vice President, Affiliated Hospital of Luzhou Medical College, China1999.05-2005.09 Director, Vascular Surgery Department, Affiliated Hospital of Luzhou Medical College, China1994.03-1996.05 Ph.D. candidate researcher, State Key Laboratory of Genetic Engineering in Fudan University

研究领域

Stem cell transplantation for ischemic limbDiabetesAcute pancreatitis and small intestine against ischemia/reperfusion injuryGenomeAtherosclerosis and Thrombosis

近期论文

Representative Publications in recent 5 yearsXiao-lei Sun, Betty Yuen-Kwan Law, Ivo Ricardo de Seabra Rodrigues Dias, Simon Wing Fai Mok, Yan-zheng He*, Vincent Kam-Wai Wong. Pathogenesis of thromboangiitis obliterans: Gene polymorphism and immunoregulation of human vascular endothelial cells. Atherosclerosis 2017 Aug 18. pii: S0021-9150(17)31231-5. doi: 10.1016/j.atherosclerosis.2017.08.009.Yong Liu, Wei-Ming Wang, Xue-Lin Zhang,* Hu-Qiang He, Xiao-Lei Sun, Hong Zeng, Xiong-Fei Xu, Liang Huang, Zhi Zhu, Lei Zhang, Xiang-Yu Zhou, and Yan-Zheng He*. AGE/RAGE promotes thecalcification of human aortic smooth muscle cells via the Wnt/β-catenin axis. Am J Transl Res. 2016 Nov 15;8(11):4644-4656Sun X, Jiao X, Ma Y, Liu Y, Zhang L, He Y*, Chen Y. Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome. Biochem Biophys Res Commun. 2016 Dec 2;481(1-2):63-70.L Song, S Shi, W Jiang, X Liu, Y He*. Protective role of propofol on the kidney during early unilateral ureteral obstruction through inhibition of epithelial-mesenchymal transition. Am J Transl Res 2016;8(2):460-472Li Song, Shi Sen, Yuhong Sun, Jun Zhou, Liqun Mo, Yanzheng He*. Ketamine inhalation ameliorates Ovalbumin-induced murine asthma by suppressing the epithelial-mesenchymal transition. Med Sci Monit, 2016; 22: 2471-2483Liu Y, Liao WJ, Zhu Z, Zeng H, He HQ, Sun XL, Xu XF, Huang L, Wang WM, Zhou XY, He YZ*. Effect of procyanidine on VEGFR-2 expression and transduction pathway in rat endothelial progenitor cells under high glucose conditions. Genet Mol Res. GMR, 2016,15(1)Yong Liu, Lei Zhang, Hong Zeng, Xiao-Lei Sun, Hu-Qiang He, Wei-Ming Wang, Liang Huang, Xue-Lin Zhang, Wen-Jun Liao, Yan-Zheng He*. PDGF-BB activated Rac-1 in regulation of inner and outer nuclear distribution of rat aortic smooth muscle cell β-catenin. Int J Clin Exp Med. 2016;9(11):20801-20813.Zhou X, Liu Z, Cheng X, Zheng Y, Zeng F, He Y*.Socs1 and Socs3 degrades Traf6 via polyubiquitination in LPS-induced acute necrotizing pancreatitis, Cell Death Dis,2015,6:e2012-e2012.Hu-Qiang He,Yong Liu, Hong Zeng, Xiao-Lei Sun, Lei Zhang, Xue-Lin Zhang, Wen-Jun Liao, Xiang-Yu Zhou, Yan-Zheng He*. Advanced glycation endproducts regulate smooth muscle cells calcification in cultured HSMCs. Int J Clin Exp Patho. 2015,8(10):12260-12267.Yong Liu, Fei Xei, Xiong-Fei Xu, Hong Zeng , Hu-Qiang He , Lei Zhang , Ying-Qiang Zheng, Yan-Zheng He*. Experimental study on apoptosis of TNFR1 receptor pro-endothelial progenitor cells activated by highglucose induced oxidative stress. Int J Clin Exp Med. 2015 Nov 15;8(11):19969-81.eCollection 2015.Zhou X, Liu Z, Jang F, Xiang C, Li Y, He Y*.Autocrine Sonic hedgehog attenuates inflammation in cerulein-induced acute pancreatitis in mice via upregulation of IL-10. PLoS One. 2012;7(8):e44121.Zhou X, Yuan P, He Y*. Role of microRNAs in peripheral artery disease. Mol Med Rep.2012 Oct;6(4):695-700.He X, Zheng Y, Liu S, Shi S, Liu Y, He Y, Zhang C, Zhou X.miR-146a protects small intestine against ischemia/reperfusion injury by down-regulating TLR4/TRAF6/NF-κB pathway. J Cell Physiol. 2017 Aug 3. doi: 10.1002/jcp.26124.Wang X, He X, Deng X, He Y, Zhou X.Roles of miR‑4463 in H2O2‑induced oxidative stress in human umbilical vein endothelial cells. Mol Med Rep. 2017 Sep;16(3):3242-3252.Xu JY, Chang NB, Li T, Jiang R, Sun XL, He YZ, Jiang J. Endothelial Cells Inhibit the Angiotensin II Induced Phenotypic Modulation of Rat Vascular Adventitial Fibroblasts. J Cell Biochem. 2017 Feb 20. doi: 10.1002/jcb.25941.He XM, Zheng YQ, Liu SZ, Liu Y, He YZ, Zhou XY. Altered Plasma MicroRNAs as Novel Biomarkers for Arteriosclerosis Obliterans, J Atheroscler Thromb, 2016,23(2):196-206.Zhu J, Xia J, Jiang J, Jiang R, He Y, Lin H.Effects of estrogen deprivation on expression of aquaporins in rat vagina. Menopause. 2015 Aug;22(8):893-8.Sen S, He Y, Koya D, Kanasaki K. Cancer biology in diabetes. J Diabetes Investig. 2014; 5(3):251-64.*Corresponding authors