个人简介

Systematic quality evaluation of Chinese MedicineDrug discovery and developmentMedicinal administrationAcademic QualificationsPostgraduate, Chongqing Medical UniversityBSc, Chengdu University of Chinese MedicineTeachingIntroduction to Research in Chinese Medicinal Science (MCMC103)Introduction to Research in Medical Administration (MCMC110)

研究领域

Systematic quality evaluation of Chinese MedicineDrug discovery and developmentMedicinal administration

近期论文

Book chapters / Monographsa.Advances in Chinese Medicinal Approach to Cancer. Beijing: People’s Medical Publishing House, 2012, ISBN 9787117162272, 7117162279. Chief Editorb.Chromatographic Analysis of Commonly Used Chinese Material Medica, Macao: University of Macau Press, 2009, ISBN 978-99937-970-6-7. Co-Chief Editor.c.Pharmacological Activity-Based Quality Control of Chinese Herbs, Nova Science Publishers, Inc, 2008, ISBN-10: 1-60456-823-2. Co-Chief Editor.d.Chinese Medical Sciences collection Series (A)–Progress in Medicinal Administration Research. Macao: University of Macau Press, 2005, ISBN 99937-26-50-8. Chief Editor.e.Chinese Medical Sciences collection Series (B)–Progress in Traditional Chinese Medical Research. Macao: University of Macau Press, 2005, ISBN 99937-26-51-6. Chief Editor.f.Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 1. Macao: University of Macau Press, 2005, ISBN 99937-26-52-4. Chief Editor.g.Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 2. Macao: University of Macau Press, 2005, ISBN 99937-26-53-2. Chief Editor.h.Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 3. Macao: University of Macau Press, 2005, ISBN 99937-26-54-0. Chief Editor.i.Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 4. Macao: University of Macau Press, 2005, ISBN 99937-26-55-9. Chief Editor.j.Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 5. Macao: University of Macau Press, 2005, ISBN 99937-26-56-7. Chief Editor.k.Chinese Medical Sciences collection Series (C) – Quality Evaluation for Chinese Medicine 6. Macao: University of Macau Press, 2005, ISBN 99937-26-57-5. Chief Editor.l.Chinese Terms in Chinese Medicine and Pharmacy. Beijing: Science Press, 2005, ISBN 7-03-015154-2, Associate Editor.m.Intellectual Property Protection of TCM. Beijing: China Press of TCM, 2003, ISBN 7-80-15641-89, Chief Editor.n.Drug Administration of European Union and Traditional Chinese Medicine. China International Culture Press Limited, 1999, Associate Editor.o.Traditional Chinese Medicine pharmacology and application. Beijing: People’s Medical Publishing House, 1997, ISBN 7-117-03057-7/R.3058, Associate Editor.p.New product development from Traditional Chinese Medicine. Beijing: People’s Medical Publishing House, 1997, ISBN 7-117-02640-5, Chief Editor.International peer-reviewed journals （01/2010-2018/11）1.Xiong W, Zhao GD, Yin XQ, Gang LHK, Chu JMT, Wong GTC, Li HF, Yu H, Wang YT. Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations. Carbohydrate Polymers. 2019; 204:89-96.2.Zhou FY, Wang AQ, Li D, Wang YT, Lin LG. Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway. Toxicology and Applied Pharmacology. 2018; 341:38-50.3.Zhong ZF, Yu HB, Wang SP, Wang YT, Cui L. Anti-cancer effects of Rhizoma Curcumae against doxorubicin-resistant breast cancer cells. Chinese Medicine. 2018; 13.4.Zhao QQ, Miriyala N, Su Y, Chen WJ, Gao XJ, Shao L, Yan R, Li HF, Yao XJ, Cao DS, Wang YT, Ouyang DF. Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System. Molecular Pharmaceutics. 2018; 15:1664-1673.5.Zhang LL, Feng ZL, Su MX, Jiang XM, Chen XP, Wang YT, Li A, Lin LG, Lu JJ. Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells. European Journal of Pharmacology. 2018; 830:17-25.6.Zhang L, Dou XW, Zhang C, Ying GY, Liu CM, Luo JY, Li Q, Li P, Wang YT, Yang MH. Facile preparation of stable PEG-functionalized quantum dots with glycine-enhanced photoluminescence and their application for screening of aflatoxin B-1 in herbs. Sensors and Actuators B-Chemical. 2018; 261:188-195.7.Zhane JM, Fang XB, Li ZY, Chan HF, Lin ZX, Wang YT, Chen MW. Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol. International Journal of Nanomedicine. 2018; 13:939-956.8.Xiong W, Sang W, Linghu KG, Zhong ZF, Cheang WS, Li J, Hu YJ, Yu H, Wang YT. Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine. International Journal of Nanomedicine. 2018; 13:3781-3793.9.Xia FB, Li A, Chai YS, Xiao X, Wan JB, Li P, Wang YT. UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar. Frontiers in Pharmacology. 2018; 9.10.Wei JC, Wei B, Yang W, He CW, Su HX, Wan JB, Li P, Wang YT. Trace determination of carbamate pesticides in medicinal plants by a fluorescent technique. Food and Chemical Toxicology. 2018; 119:430-437.11.Wang SP, Xu YQ, Li CY, Tao HX, Wang AQ, Sun CY, Zhong ZF, Wu X, Li P, Wang YT. Gambogic acid sensitizes breast cancer cells to TRAIL-induced apoptosis by promoting the crosstalk of extrinsic and intrinsic apoptotic signalings. Food and Chemical Toxicology. 2018; 119:334-341.12.Wang AQ, Wang SP, Zhou FY, Li P, Wang YT, Gan LS, Lin LG. Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. Biomedicine & Pharmacotherapy. 2018; 101:334-341.13.Wang AQ, Li D, Wang SP, Zhou FY, Li P, Wang YT, Lin LG. gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction. Journal of Functional Foods. 2018; 40:544-553.14.Tao HX, Xiong W, Zhao GD, Peng Y, Zhong ZF, Xu L, Duan R, Tsim KWK, Yu H, Wang YT. Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach. Food and Chemical Toxicology. 2018; 119:400-406.15.Song QQ, Liu WJ, Chen XJ, Li J, Li P, Yang FQ, Wang YT, Song YL, Tu PF. Serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring, a fit-for-purpose tool for large-scale targeted metabolomics of medicinal bile. Analytica Chimica Acta. 2018; 1037:119-129.16.Shen SN, Liao QW, Huang L, Li D, Zhang QW, Wang YT, Lee SMY, Lin LG. Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice. Journal of Functional Foods. 2018; 47:192-199.17.Sang W, Zhong ZF, Linghu KG, Xiong W, Tse AKW, Cheang WS, Yu H, Wang YT. Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation. Chinese Medicine. 2018; 13.18.Qu LP, Zou WJ, Wang YT, Wang M. European regulation model for herbal medicine: The assessment of the EU monograph and the safety and efficacy evaluation in marketing authorization or registration in Member States. Phytomedicine. 2018; 42:219-225.19.Ma XW, Hu YC, Li X, Zheng XT, Wang YT, Zhang JM, Fu CM, Geng FN. Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation. Frontiers in Pharmacology. 2018; 9.20.Luo WW, Zhao WW, Lu JJ, Wang YT, Chen XP. Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells. Chinese Journal of Natural Medicines. 2018; 16:10-19.21.Luo W, Liu X, Sun W, Lu JJ, Wang YT, Chen XP. Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway. Phytotherapy Research. 2018; 32:2009-2020.22.Liu Y, Song QQ, Liu WJ, Li P, Li J, Zhao YF, Zhang L, Tu PF, Wang YT, Song YL. Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry. Acta Pharmaceutica Sinica B. 2018; 8:645-654.23.Liu WJ, Song QQ, Yan Y, Liu Y, Li P, Wang YT, Tu PF, Song YL, Li J. Integrated approach for confidence-enhanced quantitative analysis of herbal medicines, Cistanche salsa as a case. Journal of Chromatography A. 2018; 1561:56-66.24.Liu JX, Shen SN, Tong Q, Wang YT, Lin LG. Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3. European Journal of Pharmacology. 2018; 834:176-187.25.Li F, Li XM, Sheng DK, Chen SR, Nie X, Liu ZY, Wang DC, Zhao Q, Wang YT, Wang Y, Zhou GC. Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity. Rsc Advances. 2018; 8:9440-9456.26.Li A, Zhang JY, Xiao X, Wang SS, Wan JB, Chai YS, Li P, Wang YT. Hepatorenal protective effects of medicinal herbs in An-Gong-Niu-Huang Wan (AGNH) against cinnabar- and realgar-induced oxidative stress and inflammatory damage in mice. Food and Chemical Toxicology. 2018; 119:445-456.27.Chen SR, Li F, Ding MY, Wang DC, Zhao Q, Wang YT, Zhou GC, Wang Y. Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice. Bioorganic & Medicinal Chemistry. 2018; 26:5053-5061.28.Chen SR, Dai Y, Zhao J, Lin LG, Wang YT, Wang Y. A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F. Frontiers in Pharmacology. 2018; 9.29.Cao JL, Wang SS, Hu H, He CW, Wan JB, Su HX, Wang YT, Li P. Online comprehensive two-dimensional hydrophilic interaction chromatography x reversed-phase liquid chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry for the analysis of phenolic acids in Salvia miltiorrhiza. Journal of Chromatography A. 2018; 1536:216-227.30.Bao JL, Ding RB, Jia XJ, Liang YE, Liu F, Wang K, Zhang C, Li P, Wang YT, Wan JB, He CW. Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches. Journal of Pharmaceutical and Biomedical Analysis. 2018; 154:312-320.31.Zhong ZF, Yu HB, Wang CM, Qiang WA, Wang SP, Zhang JM, Yu H, Cui L, Wu T, Li DQ, Wang YT. Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-kappa B-Independent Mechanism. Frontiers in Pharmacology. 2017; 8.32.Zhong ZF, Yu HB, Wang CM, Qiang WA, Wang SP, Zhang JM, Yu H, Cui L, Wu T, Li DQ, Wang YT. Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-kappa B-Independent Mechanism (vol 8, 648, 2017). Frontiers in Pharmacology. 2017; 8.33.Zhong ZF, Tan W, Tian K, Yu H, Qiang WA, Wang YT. Combined effects of furanodiene and doxorubicin on the migration and invasion of MDA-MB-231 breast cancer cells in vitro. Oncology Reports. 2017; 37:2016-2024.34.Zhao QQ, Zhang WX, Wang RM, Wang YT, Ouyang DF. Research Advances in Molecular Modeling in Cyclodextrins. Current Pharmaceutical Design. 2017; 23:522-531.35.Zhang WX, Zhao QQ, Deng JL, Hu YJ, Wang YT, Ouyang DF. Big data analysis of global advances in pharmaceutics and drug delivery 1980-2014. Drug Discovery Today. 2017; 22:1201-1208.36.Zhang WX, Wang YT, Ouyang DF. Diversity of Pharmacy Faculty Members between UK and US. Indian Journal of Pharmaceutical Education and Research. 2017; 51:20-24.37.Zhang QR, Yu H, Qi J, Tang DS, Chen XJ, Wan JB, Li P, Hu H, Wang YT, Hu YJ. Natural formulas and the nature of formulas: Exploring potential therapeutic targets based on traditional Chinese herbal formulas. Plos One. 2017; 12.38.Zhang JM, Zheng YF, Xie X, Wang L, Su ZR, Wang YT, Leong KW, Chen MW. Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy. Molecular Pharmaceutics. 2017; 14:3644-3659.39.Zhang JM, Wang L, Chan HF, Xie W, Chen S, He CW, Wang YT, Chen MW. Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells. Scientific Reports. 2017; 7.40.Zhang JM, Li JJ, Shi Z, Yang Y, Xie X, Lee SM, Wang YT, Leong KW, Chen MW. pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities. Acta Biomaterialia. 2017; 58:349-364.41.Yao DN, Xi XY, Huang YK, Hu H, Hu YJ, Wang YT, Yao WB. A national survey of clinical pharmacy services in county hospitals in China. Plos One. 2017; 12.42.Yan Y, Song QQ, Chen XJ, Li J, Li P, Wang YT, Liu TX, Song YL, Tu PF. Simultaneous determination of components with wide polarity and content ranges in Cistanche tubulosa using serially coupled reverse phase-hydrophilic interaction chromatography-tandem mass spectrometry. Journal of Chromatography A. 2017; 1501:39-50.43.Xu XH, Zhang LL, Wu GS, Chen X, Li T, Chen XP, Wang YT, Lu JJ. Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian Cancer Cells. Planta Medica. 2017; 83:254-260.44.Xu XH, Liu QY, Li T, Liu JL, Chen X, Huang L, Qiang WA, Chen XP, Wang YT, Lin LG, Lu JJ. Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells. Scientific Reports. 2017; 7.45.Wu X, Wang SP, Li MX, Wang AQ, Zhou YY, Li P, Wang YT. Nanocarriers for TRAIL delivery: driving TRAIL back on track for cancer therapy. Nanoscale. 2017; 9:13879-13904.46.Wu WJ, Yan R, Li T, Li YP, Zhou RN, Wang YT. Pharmacokinetic alterations of rhubarb anthraquinones in experimental colitis induced by dextran sulfate sodium in the rat. Journal of Ethnopharmacology. 2017; 198:600-607.47.Wu MY, Wang SF, Cai CZ, Tan JQ, Li M, Lu JJ, Chen XP, Wang YT, Zheng W, Lu JH. Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity. Oncotarget. 2017; 8:77673-77684.48.Wei JC, Cao JL, Hu H, Yang Q, Yang FQ, Wan JB, Su HX, He CW, Li P, Wang YT. Sensitive and Selective Detection of Oxo-Form Organophosphorus Pesticides Based on CdSe/ZnS Quantum Dots. Molecules. 2017; 22.49.Wang YF, Xu YL, Tang ZH, Li T, Zhang LL, Chen XP, Lu JH, Leung CH, Ma DL, Qiang WA, Wang YT, Lu JJ. Baicalein Induces Beclin 1-and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells. American Journal of Chinese Medicine. 2017; 45:123-136.50.Wang YF, Tang ZH, Li T, Xu XH, Chen XP, Wang Y, Wang YT, Lu JJ. Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal. Molecular Medicine Reports. 2017; 16:8392-8398.51.Wang SP, Wang AQ, Shao M, Lin LG, Li P, Wang YT. Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin. Scientific Reports. 2017; 7.52.Wang SP, Shao M, Zhong ZF, Wang AQ, Cao JL, Lu YC, Wang YT, Zhang JM. Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer. Drug Delivery. 2017; 24:1791-1800.53.Wang CM, Lei CK, Wang RB, Xiao JB, Wang YT. Ten years of exploration, a new journey to start: advancing Chinese Medicine to the next level. Chinese Medicine. 2017; 12.54.Tang ZH, Zhang LL, Chen X, Chen XP, Wang YT, Lu JJ. The effects and mechanisms of two main constituents from Glycyrrhiza uralensis Fisch-induced autophagy in non-small cell lung cancer. Biochemical Pharmacology. 2017; 139:123-123.55.Tan W, Zhong ZF, Wang SP, Liu H, Yu H, Tan R, Hu XD, Pan TR, Wang YT. The Typical Metabolic Modifiers Conferring Improvement in Cancer Resistance. Current Medicinal Chemistry. 2017; 24:3698-3710.56.Sun W, Wang S, Zhao WW, Wu CH, Guo SH, Gao HW, Tao HX, Lu JJ, Wang YT, Chen XP. Chemical constituents and biological research on plants in the genus Curcuma. Critical Reviews in Food Science and Nutrition. 2017; 57:1451-1523.57.Song YL, Song QQ, Liu Y, Li J, Wan JB, Wang YT, Jiang Y, Tu PF. Integrated work-flow for quantitative metabolome profiling of plants, Peucedani Radix as a case. Analytica Chimica Acta. 2017; 953:40-47.58.Song QQ, Zhao YF, Chen XJ, Li J, Li P, Jiang Y, Wang YT, Song YL, Tu PF. New instrumentation for large-scale quantitative analysis of components spanning a wide polarity range by column-switching hydrophilic interaction chromatography-turbulent flow chromatography-reversed phase liquid chromatography-tandem mass spectrometry. Rsc Advances. 2017; 7:31838-31849.59.Song QQ, Liu WJ, Yan Y, Li P, Li J, Tu PF, Wang YT, Song YL. Polarity-extended quantitative analysis of bear bile and its analogues using serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring. Rsc Advances. 2017; 7:52822-52831.60.Niu YM, Li Q, Xie RY, Liu S, Wang RB, Xing PF, Shi YC, Wang YT, Dong L, Wang CM. Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material. Biomaterials. 2017; 139:39-55.61.Nie X, Chen SR, Wang K, Peng YR, Wang YT, Wang DC, Wang Y, Zhou GC. Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-kappa B Signaling Pathway. Scientific Reports. 2017; 7.62.Ni JY, Zhao JR, Ung COL, Hu YJ, Hu H, Wang YT. Obstacles and opportunities in Chinese pharmaceutical innovation. Globalization and Health. 2017; 13.63.Liu LJ, Wang WH, Zhong ZF, Lin S, Lu LH, Wang YT, Ma DL, Leung CH. Inhibition of TLR1/2 dimerization by enantiomers of metal complexes (vol 52, pg 12278, 2016). Chemical Communications. 2017; 53:1325-1325.64.Li YX, Gong XH, Liu MC, Peng C, Li P, Wang YT. A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb. Evidence-Based Complementary and Alternative Medicine. 2017.65.Li YX, Gong XH, Liu MC, Peng C, Li P, Wang YT. Investigation of Liver Injury of Polygonum multiflorum Thunb. in Rats by Metabolomics and Traditional Approaches. Frontiers in Pharmacology. 2017; 8.66.Li Q, Niu YM, Diao HJ, Wang LT, Chen XP, Wang YT, Dong L, Wang CM. In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing. Biomaterials. 2017; 148:54-68.67.Li A, Zhang XX, Shu M, Wu MJ, Wang J, Zhang JY, Wang R, Li P, Wang YT. Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy. Phytomedicine. 2017; 30:28-41.68.Li A, Zhang JY, Zhang XX, Wang J, Wang SS, Xiao X, Wang R, Li P, Wang YT. Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor beta-independent mechanism. Scientific Reports. 2017; 7.69.Jing WH, Gao XJ, Han BL, Wei B, Hu N, Li S, Yan R, Wang YT. Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms. Rsc Advances. 2017; 7:2594-2605.70.Huang LJ, Chen SR, Yuan CM, Gu W, Guo BJ, Wang YT, Wang Y, Hao XJ. C-21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents. Bioorganic & Medicinal Chemistry. 2017; 25:3512-3524.71.Huang L, Feng ZL, Wang YT, Lin LG. Anticancer carbazole alkaloids and coumarins from Clausena plants: A review. Chinese Journal of Natural Medicines. 2017; 15:881-888.72.Guo BJ, Bian ZX, Qiu HC, Wang YT, Wang Y. Biological and clinical implications of herbal medicine and natural products for the treatment of inflammatory bowel disease. Annals of the New York Academy of Sciences. 2017; 1401:37-48.73.Feng ZL, Li D, Liu QY, Liu JX, Huang L, Zhang QW, Wang YT, Lin LG. Anti-inflammatory abietane diterpenoids from the seeds of Podocarpus nagi. Phytochemistry Letters. 2017; 21:260-263.74.Feng HT, Zhao WW, Lu JJ, Wang YT, Chen XP. Hypaconitine inhibits TGF-beta 1-induced epithelial-mesenchymal transition and suppresses adhesion, migration, and invasion of lung cancer A549 cells. Chinese Journal of Natural Medicines. 2017; 15:427-435.75.Feng HT, Lu JJ, Wang YT, Pei LX, Chen XP. Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells. Cell Adhesion & Migration. 2017; 11:464-475.76.Chen X, Wu QS, Meng FC, Tang ZH, Chen XP, Lin LG, Chen P, Qiang WA, Wang YT, Zhang QW, Lu JJ. Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells (vol 23, pg 1555, 2016). Phytomedicine. 2017; 29:E1-E1.77.Chen FQ, Zhang JM, Fang XF, Yu H, Liu YL, Li H, Wang YT, Chen MW. Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of alpha-tocopheryl succinate-based polyphosphoester copolymers. Acta Pharmacologica Sinica. 2017; 38:859-873.78.Cao H, Wang YT, Xiao JB. Dietary Polyphenols and Type 2 Diabetes: Human Study and Clinical Trial. Free Radical Biology and Medicine. 2017; 112:158-158.79.Cao H, Chai TT, Wang X, Morais-Braga MFB, Yang JH, Wong FC, Wang RB, Yao HK, Cao JG, Cornara L, Burlando B, Wang YT, Xiao JB, Coutinho HDM. Phytochemicals from fern species: potential for medicine applications. Phytochemistry Reviews. 2017; 16:379-440.80.Bao JL, Ding RB, Liang YE, Liu F, Wang K, Jia XJ, Zhang C, Chen MW, Li P, Su HX, Wan JB, Wang YT, He CW. Differences in Chemical Component and Anticancer Activity of Green and Ripe Forsythiae Fructus. American Journal of Chinese Medicine. 2017; 45:1513-1536.81.Zou LD, Chen FQ, Bao JL, Wang SP, Wang L, Chen MW, He CW, Wang YT. Preparation, characterization, and anticancer efficacy of evodiamine-loaded PLGA nanoparticles. Drug Delivery. 2016; 23:908-916.82.Zhong ZF, Tan W, Qiang WW, Scofield VL, Tian K, Wang CM, Qiang WA, Wang YT. Furanodiene alters mitochondrial function in doxorubicin-resistant MCF-7 human breast cancer cells in an AMPK-dependent manner. Molecular Biosystems. 2016; 12:1626-1637.83.Zhong ZF, Qiang WW, Tan W, Zhang HT, Wang SP, Wang CM, Qiang WN, Wang YT. Chinese Herbs Interfering with Cancer Reprogramming Metabolism. Evidence-Based Complementary and Alternative Medicine. 2016.84.Zhong ZF, Qiang WA, Wang CM, Tan W, Wang YT. Furanodiene enhances the anti-cancer effects of doxorubicin on ER alpha-negative breast cancer cells in vitro. European Journal of Pharmacology. 2016; 774:10-19.85.Zhang M, Kong XJ, Zheng J, Wan JB, Wang YT, Hu YJ, Shao R. Research and development of antibiotics: insights from patents and citation network. Expert Opinion on Therapeutic Patents. 2016; 26:617-627.86.Zhang LL, Xu YL, Tang ZH, Xu XH, Chen X, Li T, Ding CY, Huang MQ, Chen XP, Wang YT, Yuan XF, Lu JJ. Effects of alisol B 23-acetate on ovarian cancer cells: G1 phase cell cycle arrest, apoptosis, migration and invasion inhibition. Phytomedicine. 2016; 23:800-809.87.Zhang LL, Tian K, Tang ZH, Chen XJ, Bian ZX, Wang YT, Lu JJ. Phytochemistry and Pharmacology of Carthamus tinctorius L. American Journal of Chinese Medicine. 2016; 44:197-226.88.Zhang C, Jia XJ, Bao JL, Chen SH, Wang K, Zhang YL, Li P, Wan JB, Su HX, Wang YT, Mei ZN, He CW. Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways. Bmc Complementary and Alternative Medicine. 2016; 16.89.Yang BR, Hong SJ, Lee SMY, Cong WH, Wan JB, Zhang ZR, Zhang QW, Zhang Y, Wang YT, Lin ZX. Pro-angiogenic activity of notoginsenoside R1 in human umbilical vein endothelial cells in vitro and in a chemical-induced blood vessel loss model of zebrafish in vivo. Chinese Journal of Integrative Medicine. 2016; 22:420-429.90.Xu XH, Li T, Fong CMV, Chen XP, Chen XJ, Wang YT, Huang MQ, Lu JJ. Saponins from Chinese Medicines as Anticancer Agents. Molecules. 2016; 21.91.Xu HB, Song JY, Luo HM, Zhang YJ, Li QS, Zhu YJ, Xu J, Li Y, Song C, Wang B, Sun W, Shen GA, Zhang X, Qian J, Ji AJ, Xu ZC, Luo X, He L, Li CY, Sun C, Yan HX, Cui GH, Li XW, Li XE, Wei JH, Liu JY, Wang YT, Hayward A, Nelson D, Ning Z, Peters RJ, Qi XQ, Chen SL. Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza. Molecular Plant. 2016; 9:949-952.92.Wang SP, Zhang JM, Wang YT, Chen MW. Hyaluronic acid-coated PEI-PLGA nanoparticles mediated co-delivery of doxorubicin and miR-542-3p for triple negative breast cancer therapy. Nanomedicine-Nanotechnology Biology and Medicine. 2016; 12:411-420.93.Wang SP, Xu YQ, Chan HF, Kim HW, Wang YT, Leong KW, Chen MW. Nanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy. Journal of Controlled Release. 2016; 240:454-464.94.Wang CZ, Yu CH, Wen XD, Chen LN, Zhang CF, Calway T, Qiu YP, Wang YW, Zhang ZY, Anderson S, Wang YT, Jia W, Yuan CS. American Ginseng Attenuates Colitis-Associated Colon Carcinogenesis in Mice: Impact on Gut Microbiota and Metabolomics. Cancer Prevention Research. 2016; 9:803-811.95.Wang AQ, Wang SP, Jiang Y, Chen MW, Wang YT, Lin LG. Bio-assay guided identification of hepatoprotective polyphenols from Penthorum chinense Pursh on t-BHP induced oxidative stress injured L02 cells. Food & Function. 2016; 7:2074-2083.96.Ung COL, Chao CK, Hu YJ, Zhao J, Li P, Wang YT, Hu H. Community pharmacists’ understanding, attitudes, practice and perceived barriers related to providing pharmaceutical care: a questionnaire-based survey in Macao. Tropical Journal of Pharmaceutical Research. 2016; 15:847-854.97.Tang ZH, Chen X, Wang ZY, Chai K, Wang YF, Xu XH, Wang XW, Lu JH, Wang YT, Chen XP, Lu JJ. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Scientific Reports. 2016; 6.98.Ren GW, Luo WW, Sun W, Niu YA, Ma DL, Leung CH, Wang YT, Lu JJ, Chen XP. Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. Phytomedicine. 2016; 23:939-947.99.Ni JY, Wan JB, Kong XJ, Cai Y, Yang FQ, Wang YT, Hu YJ. Pharmaceutical Technology Licensing: An Analysis in the Field of Cardiovascular Disease. 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