个人简介

谢中稳，安徽农业大学全职特聘教授。知名专家，博士，博士生导师。主要研究领域：茶叶的有效成份对心血管系统保护的分子机制; 茶叶多酚类化合物对糖和脂代謝调控的分子机制; 茶叶的有效成份对生物鐘系统调控的分子机制。1999年获中国科学院植物研究所植物学专业博士学位。2000年7月至2003 年7月在University of Kentucky, Graduate Center for Toxicology从事博士后研究；2003年7月至2012年12月在University of Kentucky, Graduate Center for Nutritional Sciences从事研究，任研究科学家和资深研究科学家。先后参与国家自然科学基金重大项目和美国NIH R01项目的研究。在Journal of Clinical Investigation (IF:13.765); Nucleic Acids Research (IF:8.808) J Biol Chem (IF：4.651)、Arteriosclerosis, Thrombosis, and Vascular Biology (IF：6.338)、Cardiovascular research (IF：5.94)、 Am J Physiol –Heart and C (IF：3.629)等国际知名杂志发表论文30多篇，总计被引次数近千次，H因子16。

研究领域

茶与健康

近期论文

1. Cheng H, Xu N, Zhao W, Su J, Liang M, Xie Z*, Wu X, Li Q. 2017. (-)-Epicatechin regulates blood lipids and attenuates hepatic steatosis in rats fed high-fat diet. Mol Nutr Food Res. 2017 Jul 21. doi: 10.1002/mnfr.201700303.2. Zhang J.,Pan G.,Chen Y.,Xiang C.,Chen Z.,Xie Z*. and Ling X*.2017 Quantitative detection of transgenic maize event VCO-01981-5 with droplet digital PCR. Food Science 38(12): 246-252.3. Wang J., Qiu B., Liu M., Wang C. Yong W and Xie Z*. 2016 Influence of protein phosphatase 5 on the lipid metabolism in mice. Chinese Journal of comparative Medicine 26(8): 61-664. Xie, Z., Su W.,, Liu S., Zhao G., Esser, K., Schroder EA., Lefta M., Stauss HM.,，Guo Z and Gong M. 2015.Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation.The Journal of clinical investigation 125 (1), 324-336 5. Huang J., Xie Z., Wang Y., Zhang J. and Wan X. Recent advances of anti-hyperglycemia and anti-diabetes actions of tea in animal studies. Current Opinion in Food Science. 2015; 2:78-83 6. Huang J., Wang Y., Xie Z., Zhou Y. and Wan X. The anti-obesity effects of green tea in human intervention and basic molecular studies. European Journal of Clinic Nutrition 2014; 68, 1075-10877. Jiang L., Li W., Wang Y., Zhang X, Yu D., Yin Y., Xie Z., and Yuan Y. 2014, Effects of Cichoric Acid Extract from Echinacea purpurea on Collagen-induced Arthritis in Rats. The American J of Chinese Medicine 42(3): 679-6928. Huang J. , Zhang Y. , Zhou Y. , Zhang Z., Xie Z., Zhang J. , and Wan X. 2013,Green Tea Polyphones Alleviate Obesity in Broiler Chickens through the Regulation of Lipid-Metabolism-Related Genes and Transcription Factor Expression. Journal of Agricultural Food Chemistry 61 (36), 8565–85729. Yu D., Yuan Y., JiangL.,Tai Y., Yang X., Hu F. and Xie Z. 2013,Anti-inflammatory effects of essential oil in Echinacea purpurea L. Pakistan Journal of Pharmaceutical. Science 26(2), 403-40810. Liu S., Xie Z., Daugherty, A., Cassis L., Pwarson K., Gong MC. and GuoZ.. 2013, Mineralocorticoid Receptor Agonists Induce Mouse Aortic Aneurysm Formation and Rupture in the Presence of High Salt. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1568-1579 11. Su W, Xie Z, (co-first authors), Liu S, Calderon LE, Guo Z, Gong MC.2013, Smooth muscle-selective CPI-17 expression increases vascular smooth muscle contraction and blood pressure. American Journal of Physiology-Heart and Circulatory Physiology 305(1): H104-13 12. Kuang L., Kou H., Xie Z.,Zhou Y., Feng X., Wang L. and Wang Z.. 2013, A Non-catalytic Function of Rev1 in Translation DNA Synthesis and Mutagenesis is Mediated by Its Stable Interaction with Rad5. . DNA Repair 12(1):27-3713. Liu S., Xie Z., Zhao Q. (co-first authors), Pang H., Turk J., Calderon L., Su W., Zhao G., Xu H., Gong MC and Guo Z.. 2012, Smooth Muscle-Specific Expression of iPLA β Participates in the Initiation and Early Progression of Vascular Inflammation and Neointima Formation. Journal of Biological Chemistry. 287 (29), 24739-24753 14. Calderon L., Liu S., Su W., Xie Z., Guo Z., Eberhard W. and Gong MC.2012, iPLA2β overexpression in soomth muscle exacerbates Angiotensin II-induced hypertention and vascular remodeling. PloS One 7(2): e31850 15. Su W., Xie Z., (co-first authors), Guo Z., Duncan M., Lutshumba J., Gong MC, 2012 Altered clock gene expression and vascular smooth muscle diurnal contractile variation in type 2 diabetic db/db mice. American Journal of Physiology-Heart and Circulatory Physiology 302(3): H621-33 16. Xie Z., Liu D., Liu S., Turk J., Guo, Z. 2011. Identification of a cAMP-response element in RGS2 promoter as a Key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in VSMC . Journal of Biological Chemistry. 286 (52), 44646-44658 17. Xie Z., Gong MC., Su W., Xie DP., Turk J. and Guo Z. 2010, Group VIA phospholipase A2 beta participates in high glucose induced activation of RhoA/ROCK and PKC/CPI-17 pathway in vascular smooth muscle cells and in herper-contractivity of diabetic animals. Journal of Biological Chemistry 285(12) : 8628-3718. Xie Z., Gong MC., Su W., Turk J. and Guo Z. 2007, Group VIA phospholipase A2 (iPLA2beta) participates in angiotensin II-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth muscle cells. Journal of Biological Chemistry 282(35):25278-8919. Xie Z., Su W., Guo Z., Pang H., Post SR. and Gong, MC. 2006, Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells. Cardiovascular Research 69(2):491-50120. Pang H., Guo Z., Xie Z., Su W. and Gong, MC. 2006, Divergent kinase signing mediates agonist-induced phosphorylation of phosphatase inhibitory proteins PHI and CPI-17 in vascular smooth muscle cells. American Journal of Physiology-cell physiology 290(3):C892-921. Xie Z., Zhang Y., Guliaev AB., Shen H., Huang B., Singer B., and Wang Z. 2005, The p-benzoquinone DNA adducts derived from benzene are highly mutagenic. DNA Repair 4(12):1399-40922. Pang H., Guo Z., Su W., Xie Z., Eto M., Gong MC. 2005, RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells. American Journal of Physiology-Cell Physiology 289 (2):C352-36023. Xie Z., Liu S., Zhang Y., and Wang Z. 2004, Roles of Rad23 protein in yeast nucleotide excision repair. Nucleic Acids Research 32 (20): 5981-9024. Zhao B., Xie Z., (co-first authors), Shen H., and Wang Z., 2004. Role of DNA polymerase  in the bypass of abasic sites in yeast cells. Nucleic Acids Research 32 (13): 3984-9425. Guo D., Xie Z., Shen H., and Wang Z. 2004. A non-catalytic function of Rev1 in response to acetylaminofluorene-dG DNA adducts in yeast: stimulating Pol-catalyzed translesion synthesis. Nucleic Acids Research 32 (3): 1122-3026. Xie Z., Braithwaite E., Guo D., Geacintov N., and Wang Z. 2003. Mutagenesis of Benzoapyrene diolepoxide in yeast: requirement for DNA polymerase  and involvement of DNA polymerase . Biochemistry 42(38): 11253-6227. Zhou H., Xie Z., Ge S. 2003. Microsatellite analysis of genetic diversity and population genetic structure of wild rice (Oryza rufipogon) in China. Theoretical and Applied Genetics 107 (2): 332-3928. Zhang Y., Wu X., Yuan F., Xie Z., and Wang Z. 2001. Highly frequent frame- shift DNA synthesis by human DNA polymerase . Molecular and Cellular Biology 21(23): 7995-8006 29. Xie Z., Lu Y., Ge S., Hong D., and Li F.. 2001. Clonality in wild rice (Oryza. rufipogon) and its implication for conservation managements. American Journal of Botany 88:1058-6830. Xie Z., Ge S., and Hong D., 1999. Preparation of DNA from silica gel dried mini-amount of leaves of Oryza rufipogon for RAPD studies and total DNA bank construction. Acta Botanica Sinica 41 (8): 807-812