个人简介

魏书, 植物学博士，教授, 博士生导师 以色列希伯来大学植物学博士。曾先后在中国农科院郑州果树所和江苏农科院园艺所从事果树花卉的栽培技术和脱病毒技术研究；在以色列希伯来大学攻读植物学博士学位期间，重点研究调节植物挥发性物质的合成和释放的技术；在美国明尼苏达大学和加拿大农业部萨斯卡通研究中心进行博士后的研究期间，分别研究长春花抗癌萜类生物碱的生物合成和拟南芥及油菜的胡萝卜素代谢的调控。

研究领域

植物次生代谢

植物非编码RNA及其调控网络对植物生长发育的作用机理非编码RNA是除了转录因子之外又一类调控生物基因表达的因子。是目前生物学界的研究热点。研究此类分子对植物次生代谢的调控，是魏书教授实验室的一个核心研究内容。植物香味物质生物合成途径的研究和基因工程植物合成和释放的香气物质常常对植物产品的质量有决定性的影响，这些物质也往往成为昆虫识别寄主的信息分子。通过改变植物挥发性物质生物合成和释放，不仅有可能改变植物和相关昆虫的寄主关系而减轻昆虫对植物的危害，还可以定向改变植物的香味香型，增进植物的品质。植物类胡萝卜素生物合成途径中调控因子的研究类胡萝卜素是植物通过类异戊二烯途径合成而呈现红色、橙红色和黄色的一大类色素物质的总称。是植物光吸收复合体的重要组分,并且在保护光合器官、防止光氧化损伤等方面起着重要作用，并具有重要的健康功能。对植物类胡萝卜素生物合成途径的研究已有大量的报道。但对于该途径的调控因子机制了解放非常有限。希望通过对模式之物的研究，进一步揭示植物类胡萝卜素生物合成途径中调控机制，为作物品质的改良提供依据。

近期论文

Liu G-F, …… Wei, S 2017 Metabolic Flux Redirection and transcriptomic reprogramming in the albino tea cultivar ‘Yu-Jin-Xiang’ with an emphasis on catechin production. Scientific Reports, 2017 | 7:45062 | DOI: 10.1038/srep45062. Liu-G-F, …… Wei S. Implementation of CsLIS/NES in linalool biosynthesis involves transcript splicing regulation in Camellia sinensis. Plant Cell Environ. 2017;1–11. Shen J-X, Rana MM, …… Wei S, Differential contribution of jasmine floral volatiles to the aroma of scented green tea. Journal of Food Quality, 2017, Article ID 5849501, doi.org/10.1155/2017/5849501 刘晶晶, ...... 魏书, 烟草NtWRKY40 在植物应答病毒侵染过程中的作用. 生物技术通报, 2016, 32(10):188-198. Yu B, Gruber MY, Wei S, …… Hannoufa A.Global gene expression and secondary metabolite changes in Arabidopsis thaliana ABI4 over-expression lines. Botany 94: 1–20 (2016) dx.doi.org/10.1139/cjb-2016-0043. Yi X-K, …… Wei S. Volatile profiling of two pear genotypes with different potential for white pear aroma improvement. Scientia Horticulturae, 209 (2016) 221–228. Han Z-X, Rana MM …… Wei S, Green tea flavour determinants and their changes over manufacturing processes. Food Chemistry, 212 (2016) 739–748. Rana MM, …… Wei S, Effect of medium supplements on Agrobacterium rhizogenes mediated hairy root induction from the callus tissues of Camellia sinensis var. sinensis. International Journal of Molecular Sciences 2016, 17(7):1132. DOI10.3390/ijms17071132 Shu Wei*, Yu-Zhen Xi, Da-Peng Song, Horace Wei, Margaret Y Gruberc, Ming-Jun Gao, Isobel Parkin, George Kachatourians, Abdelali Hannoufa* (2015) Quantitative and structural analyses of T-DNA tandem repeats in transgenic Arabidopsis SK mutant lines.Plant Cell, Tissue and Organ Culture, DOI 10.1007/s11240-014-0511-7, Ming-Jun Gao, Xiang Li, Jun Huang, Gordon M. Gropp, Branimir Gjetvaj, Donna L. Lindsay, Shu Wei, Cathy Coutu, Zhixiang Chen, Xiao-Chun Wan, Abdelali Hannoufa, Derek J. Lydiate, Margaret Y. Gruber, Z. Jeffrey Chen & Dwayne D. Hegedus (2015) SCARECROW-LIKE15 interacts with HISTONE DEACETYLASE19 and is essential for repressing the seed maturation programme. Nature Communications, 6:7243. D Song, L Feng, MM. Rana, M Gao, S Wei * (2014) Effects of Catechins on Agrobacterium-Mediated Genetic Transformation in Camellia sinensis. Plant Cell, Tissue and Organ Culture, 119(1):27-37. L Feng, M J Gao*, R-Y Hou, X-Y Hu, L Zhang, X-C Wan, S Wei* (2014) Determination of quality constituents in the young leaves of albino tea cultivars. Food Chemistry 155:98-104. W Xiang, Y Xu, F-M Wang, LP Gao, MI. Gruber, M-J Gao, Z Zhang, X-C Wan, S Wei*(2013) In silico analysis and feeding assays of some genes in the early steps of terpenoid biosynthetic pathway in Camellia sinensis. 茶叶, 39(4):191-198. YD Zhu,YS Jin, S Wei, H. Li, and W. Zhang (2012) Functional analysis of the isopentenyltransferase gene MdIPT3a from apple (Malus pumila Mill.). Journal of Horticultural Science & Biotechnology 87 (5): 478–484. Shu Wei, Margaret Y. Gruber, Bianyun Yu, Ming-Jun Gao, George G. Khachatourians, Dwayne D. Hegedus, Isobel A. P. Parkin, Abdelali Hannoufa(2012) Arabidopsis mutant sk156 reveals complex regulation of SPL15 in a miR156-controlled gene network. BMC Plant Biology , 12:169, doi:10.1186/1471-2229-12-169. Huang S, Shu T, Zhang J, Ma W, Wei S, Huang LQ (2102)Functional significance of some particular amino acid residues in Bombyx mori pyridoxal kinase. Comp Biochem Physiol B Biochem Mol Biol. 2012 Feb;161(2):155-60. Ming-Jun Gao, Gordon Gropp, Shu Wei et al., (2012) Combinatorial networks regulating seed development and seed filling. In Embryogenesis ISBN 979-953-307-439-8, ed. by Dr.K.Sato,Croatia, InTech Publisher. 贺志荣，项威，徐燕，高丽萍，夏涛，魏书*(2012) 茶树挥发性萜类物质及其糖苷化合物生物合成的研究进展. 茶叶科学 32（1）：1-8. (*通信作者) Shu Wei*, Abdelali Hannoufa*, Julie Soroka, Ning Xu, Xiang Li, Alireza Zebarjadi, and Margaret Gruber* (2011) Enhanced β-ionone emission in Arabidopsis over-expressing AtCCD1 reduces feeding damage in vivo by the crucifer flea beetle. Environmental Entomology 40(6): 1622-1630 (* Co-corresponding authors). ShuoHao Huang, HaiBin Zeng, JianYun Zhang, Shu Wei, LongQuan Huang (2011) Interconversions of different forms of vitamin B6 in tobacco plants. Phytochemistry 72(17): 2124-2129.doi:10.1016/j.phytochem.2011.07.019. ShuoHao Huang, HaiBin Zeng, JianYun Zhang, Shu Wei, LongQuan Huang (2011) Characterization of enzymes involved in the interconversions of different forms of vitamin B6 in tobacco leaves. Plant Physiology and Biochemistry 49(1): 1299-1305. ShuoHao Huang, Ting Shu, JianYun Zhang, Wang Ma, Shu Wei, LongQuan Huang (2011) Functional significance of some particular amino acid residues in Bombyx mori pyridoxal kinase. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 161(2): 155-160 doi:10.1016/j.cbpb.2011.10.009. Ming-Jun Gao, Xiang Li, Helen Lui, Gordon M. Gropp, Derek D. Lydiate, Shu Wei and Dwayne D. Hegedus (2011) ASIL1 is required for proper timing of seed filling in Arabidopsis. Plant Signaling & Behavior 6(12): 1886-1888. Shu Wei, Bianyun Yu, Margaret Y. Gruber, George G. Khachatourians, Dwayne D. Hegedusa, Abdelali Hannoufa (2010) Enhanced seed carotenoid levels and branching in transgenic Brassica napus expressing the Arabidopsis miR156b gene. Journal of Agricultural and Food Chemistry 58(17): 9572–9578. Shu Wei (2010) Methyl jasmonic acid induced expression pattern of terpenoid indole alkaloid pathway genes in Catharanthus roseus seedlings. Plant Growth Regulation 61(3): 243-251. Shu Wei (2009) Utility of tetracycline inducible promoter system in transgenic Catharanthus roseus hairy roots. International Journal of Plant Sciences 170(7): 829-833. Shu Wei, Xiang Li, Margaret Y. Gruber, Rong Li, Rong Zhou, Alireza Zebarjadi, Abdelali Hannoufa (2009) RNAi-mediated suppression of DET1 alters the levels of carotenoids and sinapate esters in seeds of Brassica napus. Journal of Agricultural and Food Chemistry 57 (12): 5326–5333. Renlin Xu, Shu Wei *(2009) Marker-free Technologies for Transgenic Plant Research. In: Transgenic Plants: New Research edited by Oliver T. Chan, ISBN 978-1-60692-017-6. © 2008 Nova Science Publishers, Inc. New York, USA. Suping Zhou, Shu Wei, Levy Shawn, Braden Boone (2007) Microarray analysis on salt stress affected genes in tomato seedlings. African Journal of Environmental Technology 1 (2): 014-026. Xia Liu, Songwen Wang, Yong Wang, Shu Wei* (2007) Genetic analysis and molecular mapping of a nuclear recessive male-sterile gene【ms91(t)】 in rice. Genome 50(9): 796-801 (*Corresponding author). Shu Wei, Yaniv Semel, Ben-Ami Bravdo, Henryk Czosnek, Oded Shoseyov (2007) Expression and subcellular compartmentation of Aspergillus niger ß-glucosidase in transgenic tobacco result in an increased insecticidal activity on whiteflies (Bemisia tabaci). Plant Science 172:1175–1181. Shu Wei, Ira Marton, Mara Dekel, Dror Shalitin, Efraim Lewinshon, Ben-Ami Bravdo, and Oded Shoseyov, (2004) Manipulating volatile emission in tobacco leaves by expressing Aspergillus niger β-glucosidase in different subcellular compartments. Plant Biotechnology Journal 2: 341–350. Shu Wei, Ben-Ami Bravdo, Oded Shoseyov, (2004) Fluorescent Screening of Transgenic Arabidopsis Seeds without Germination. Plant Physiology 135:709–714. Shu Wei, Haim Reuveny, Ben-Ami Bravdo, and Oded Shoseyov (2004) Hydrolysis of glycosidically bound volatiles from apple leaves (Cv. Anna) by Aspergillus niger b-glucosidase affects the behavior of codling moth (Cydia pomonella L.). Journal of Agricultural and Food Chemistry 52 (20), 6212 -6216.